Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer

Biological Chemistry

Volumn 391, Issue 8, 2010, Pages 881-892

  Maun, Henry R ^a   Kirchhofer, Daniel ^a   Lazarus, Robert A ^a  

^a GENENTECH INC   (United States)

Author keywords

Hedgehog; Hedgehog interacting protein (Hhip); Hepatocyte growth factor (HGF); Met; Metalloprotease; Pseudo active site; Pseudo protease; Serine protease

Indexed keywords

METALLOPROTEINASE; PROTEIN PATCHED 1; SCATTER FACTOR; SONIC HEDGEHOG PROTEIN; TRYPTASE; ZINC;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; BETA CHAIN; CELL PROLIFERATION; CONFERENCE PAPER; DIMERIZATION; ENGINEERING; HUMAN; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SURVIVAL;

ANIMALS; CARRIER PROTEINS; CATALYTIC DOMAIN; DRUG DESIGN; HEDGEHOG PROTEINS; HEPATOCYTE GROWTH FACTOR; HUMANS; LIGANDS; MEMBRANE GLYCOPROTEINS; METALLOPROTEASES; NEOPLASMS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTO-ONCOGENE PROTEINS C-MET; RECEPTORS, CELL SURFACE; RECEPTORS, GROWTH FACTOR; SERINE PROTEASES; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 77955938954     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2010.098     Document Type: Conference Paper

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