Structural and functional basis of the serine protease-like hepatocyte growth factor β-chain in met binding and signaling

Journal of Biological Chemistry

Volumn 279, Issue 38, 2004, Pages 39915-39924

  Kirchhofer, Daniel ^a   Yao, Xiaoyi ^a,c   Peek, Mark ^a   Eigenbrot, Charles ^a   Lipari, Michael T ^a   Billeci, Karen L ^a   Maun, Henry R ^a,b   Moran, Paul ^a   Santell, Lydia ^a   Wiesmann, Christian ^a   Lazarus, Robert A ^a  

^a GENENTECH INC   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CRYSTAL STRUCTURE; MUTAGENESIS; SUBSTRATES; TISSUE; TUMORS;

ACTIVATION DOMAIN; HEPATOCYTE GROWTH FACTOR (HGF); PROTEOLYTIC CLEAVAGES; TYROSIN KINASE;

ENZYMES;

ARGININE; ASPARTIC ACID; ENZYME PRECURSOR; GLUTAMINE; GLYCINE; MUTANT PROTEIN; PROLINE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SERINE PROTEINASE; TYROSINE; VALINE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; ASSAY; BETA CHAIN; CELL MIGRATION; CRYSTAL STRUCTURE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PURIFICATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRYSTALLOGRAPHY; DIMERIZATION; HEPATOCYTE GROWTH FACTOR; HUMANS; INSECTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MET; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION;

EID: 4544338194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404795200     Document Type: Article

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