Crystal structure of the HGF β-chain in complex with the Sema domain of the Met receptor

EMBO Journal

Volumn 23, Issue 12, 2004, Pages 2325-2335

  Stamos, Jennifer ^a,b   Lazarus, Robert A ^a   Yao, Xiaoyi ^a,c   Kirchhofer, Daniel ^a   Wiesmann, Christian ^a  

^a GENENTECH INC   (United States)

^b STANFORD UNIVERSITY   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

Hepatocyte growth factor; Ligand receptor complex; Met receptor tyrosine kinase; Sema domain; Serine protease

Indexed keywords

DIMER; HEPATOCYTE GROWTH FACTOR BETA; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SERINE PROTEINASE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BETA CHAIN; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; METASTASIS; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TUMOR GROWTH;

AMINO ACID SEQUENCE; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; HEPATOCYTE GROWTH FACTOR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PLASMON RESONANCE;

EID: 3142595278     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600243     Document Type: Article

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