The structure of vanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance

Molecular Cell

Volumn 2, Issue 1, 1998, Pages 75-84

  Bussiere, Dirksen E ^a   Pratt, Steven D ^a   Katz, Leonard ^a   Severin, Jean M ^a   Holzman, Thomas ^a   Park, Chang H ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 ((1 AMINOETHYL)PHOSPHINYL) 2 METHYLPROPIONIC ACID; 3-((1-AMINOETHYL)PHOSPHINYL)-2-METHYLPROPIONIC ACID; ALANINE; ALANYLALANINE; BACTERIAL PROTEIN; CARBOXYPEPTIDASE; CARBOXYPEPTIDASE TRANSPEPTIDASE; COPPER; CUPRIC CHLORIDE; DIPEPTIDASE; DIPEPTIDE; ENZYME INHIBITOR; ORGANOPHOSPHORUS COMPOUND; PROPIONIC ACID DERIVATIVE; PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSACTIVATOR PROTEIN; VANCOMYCIN; VANX DIPEPTIDASE; ZINC D ALA D ALA CARBOXYPEPTIDASE; ZINC D-ALA-D-ALA CARBOXYPEPTIDASE;

AMINO ACID SEQUENCE; ANIMAL; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; ENTEROCOCCUS FAECIUM; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; TRANSPOSON; X RAY CRYSTALLOGRAPHY;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CARBOXYPEPTIDASES; COPPER; CRYSTALLOGRAPHY, X-RAY; DIPEPTIDASES; DIPEPTIDES; DNA TRANSPOSABLE ELEMENTS; DRUG RESISTANCE, MICROBIAL; ENTEROCOCCUS FAECIUM; ENZYME INHIBITORS; HEDGEHOG PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ORGANOPHOSPHORUS COMPOUNDS; PROPIONIC ACIDS; PROTEIN CONFORMATION; PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATORS; VANCOMYCIN;

EID: 0032111312     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80115-X     Document Type: Article

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