Zinc-dependent structural stability of human sonic hedgehog

Biochemistry

Volumn 38, Issue 45, 1999, Pages 14868-14880

  Day, Eric S ^a   Wen, Dingyi ^a   Garber, Ellen A ^a   Hong, Jin ^b   Avedissian, Lena S ^a   Rayhorn, Paul ^a   Shen, Weihong ^a   Zeng, Chenhui ^a   Bailey, Voilaine R ^a   Reilly, Jennifer O ^c   Roden, Julie A ^a   Moore, Claire B ^a   Williams, Kevin P ^a   Galdes, Alphonse ^a   Whitty, Adrian ^a   Baker, Darren P ^a  

^a BIOGEN   (United States)

^b Ontogency Inc ^*  (United States)

^c Ontogency Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; SONIC HEDGEHOG PROTEIN; ZINC;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHICK EMBRYO; EMBRYO; ENZYME ACTIVITY; GENE MUTATION; HUMAN; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PURIFICATION; PROTEIN STABILITY;

ALKALINE PHOSPHATASE; AMINO ACID SUBSTITUTION; ANIMALS; CHICK EMBRYO; CIRCULAR DICHROISM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEDGEHOG PROTEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C3H; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATORS; ZINC;

ANIMALIA; ERINACEIDAE;

EID: 0033539473     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9910068     Document Type: Article

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