Rapid identification of small binding motifs with high-throughput phage display: Discovery of peptidic antagonists of IGF-1 function

Chemistry and Biology

Volumn 9, Issue 4, 2002, Pages 495-505

  Deshayes, Kurt ^a   Schaffer, Michelle L ^a   Skelton, Nicholas J ^a   Nakamura, Gerald R ^a   Kadkhodayan, Saloumeh ^b   Sidhu, Sachdev S ^a  

^a Department of Protein Engineering ^*  (United States)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; PEPTIDE; PEPTIDE LIBRARY; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

AMINO ACID SEQUENCE; ARTICLE; BINDING COMPETITION; BINDING SITE; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; SOLUBILITY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CELL SURFACE; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 0036233482     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00129-1     Document Type: Article

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