High throughput screening methodologies classified for major drug target classes according to target signaling pathways

Combinatorial Chemistry and High Throughput Screening

Volumn 13, Issue 6, 2010, Pages 548-561

  Kool, Jeroen ^a   Lingeman, Henk ^a   Niessen, Wilfried ^a   Irth, Hubertus ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Drug target classes; Pure compound and mixture screening; Signalling pathways; Traditional and alternative HTS assays

Indexed keywords

CELL NUCLEUS RECEPTOR; DRUG METABOLIZING ENZYME; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; ION CHANNEL; PROTEIN KINASE; PROTEINASE;

AMINO ACID SEQUENCE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CELL DEATH; DIMERIZATION; DRUG INDUSTRY; DRUG METABOLISM; DRUG TARGETING; HIGH THROUGHPUT SCREENING; LIGAND BINDING; LIQUID CHROMATOGRAPHY; LUMINESCENCE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SENSOR; SIGNAL TRANSDUCTION;

HIGH-THROUGHPUT SCREENING ASSAYS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; SIGNAL TRANSDUCTION;

EID: 77955743175     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620710791515815     Document Type: Review

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