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Volumn 819, Issue 1, 2005, Pages 169-174
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Qualitative assessment of IC50 values of inhibitors of the neuronal nicotinic acetylcholine receptor using a single chromatographic experiment and multivariate cluster analysis
a,b
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Author keywords
Affinity chromatography; Drug discovery; Immobilized receptors; Nicotinic acetylcholine receptor stationary phase
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Indexed keywords
AFFINITY CHROMATOGRAPHY;
DIALYSIS;
DRUG PRODUCTS;
MEMBRANES;
MOLECULAR DYNAMICS;
ULTRAFILTRATION;
DRUG DISCOVERY;
IMMOBILIZED RECEPTORS;
MEMBRANE-BOUND RECEPTORS;
NICOTINIC ACETYCHOLINE RECEPTOR STATIONARY PHASE;
NITROGEN COMPOUNDS;
3 HYDROXY MORPHINAN;
3 METHOXY MORPHINAN;
AMANTADINE;
AMFEBUTAMONE;
AMLODIPINE;
CLOZAPINE;
DEACETYL N NORDILTIAZEM;
DEACETYL O NORDILTIAZEM;
DEACETYLDILTIAZEM;
DEALKYLNORVERAPAMIL;
DEXTROMETHORPHAN;
DEXTRORPHAN;
DILTIAZEM;
DIZOCILPINE;
GALAPAMIL;
KETAMINE;
LAUDANOSINE;
LEVOMETHORPHAN;
MECAMYLAMINE;
MEMANTINE;
METHADONE;
METHAMPHETAMINE;
N NORDILTIAZEM;
N,O DIDEMETHYLDEACETYLDILTIAZEM;
NICARDIPINE;
NICOTINIC RECEPTOR BLOCKING AGENT;
NIFEDIPINE;
NORVERAPAMIL;
PHENCYCLIDINE;
UNCLASSIFIED DRUG;
VERAPAMIL;
NICOTINIC RECEPTOR;
AFFINITY CHROMATOGRAPHY;
ARTICLE;
CLUSTER ANALYSIS;
COHORT ANALYSIS;
DRUG ACTIVITY;
DRUG RECEPTOR BINDING;
IC 50;
LIQUID CHROMATOGRAPHY;
MULTIVARIATE ANALYSIS;
PRIORITY JOURNAL;
QUALITATIVE ANALYSIS;
THERMODYNAMICS;
METHODOLOGY;
CHROMATOGRAPHY, AFFINITY;
CLUSTER ANALYSIS;
INHIBITORY CONCENTRATION 50;
MULTIVARIATE ANALYSIS;
NICOTINIC ANTAGONISTS;
RECEPTORS, NICOTINIC;
THERMODYNAMICS;
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EID: 22844435887
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2005.01.043 Document Type: Article |
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Times cited : (16)
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References (24)
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