Multiplexing G protein-coupled receptors in microarrays: A radioligand-binding assay

Analytical Biochemistry

Volumn 365, Issue 2, 2007, Pages 266-273

  Posner, Bruce ^a   Hong, Yulong ^b   Benvenuti, Eric ^a   Potchoiba, Michael ^a   Nettleton, Dave ^a   Lui, Li ^b   Ferrie, Ann ^b   Lai, Fang ^b   Fang, Ye ^b   Miret, Juan ^a   Wielis, Chris ^a   Webb, Brian ^b  

^a PFIZER INC   (United States)

^b Corning ^*  (United States)

Author keywords

Adrenergic; GPCR; High throughput screening; Microarrays; Radioligands; Typhoon

Indexed keywords

DRUG PRODUCTS; HURRICANES; LIGANDS; MICROARRAYS; PROTEINS; STORMS;

ADRENERGIC; BIOCHEMICAL CHARACTERIZATION; G PROTEIN COUPLED RECEPTORS; GPCR; HIGH THROUGHPUT SCREENING; HIGH-THROUGHPUT ASSAYS; MEMBRANE PREPARATION; RADIOLIGANDS;

BIOASSAY;

2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 4,4 DIMETHYL 1,3(2H,4H) ISOQUINOLINEDIONE; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; CLONIDINE; G PROTEIN COUPLED RECEPTOR; IODINE 125; LIGAND;

ANIMAL CELL; ARTICLE; ARTIFICIAL MEMBRANE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; EMBRYO; FEMALE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; ISOTOPE LABELING; LIGAND BINDING; MICROARRAY ANALYSIS; MICROTITER PLATE ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RADIOASSAY; RECEPTOR BINDING; SIGNAL NOISE RATIO;

EID: 34247887378     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2007.03.014     Document Type: Article

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