Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader

Journal of Biomolecular Screening

Volumn 9, Issue 5, 2004, Pages 417-426

  Hodder, Peter ^a   Mull, Rebecca ^a   Cassaday, Jason ^a   Berry, Kurtis ^a   Strulovici, Berta ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

1536 well format; Chinese hamster ovary (CHO); FLIPR (fluorometric imaging plate reader); GPCR (G protein coupled receptor); HTS (high throughput screening); Intracellular calcium; mAchR1 receptor (muscarinic acetylcholine receptor subtype 1)

Indexed keywords

ARECOLINE; ATROPINE; CALCIUM; CARBACHOL; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR 1; CHOLINERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; IPRATROPIUM BROMIDE; MUSCARINIC AGENT; MUSCARINIC RECEPTOR BLOCKING AGENT; OXOTREMORINE; PILOCARPINE; PIRENZEPINE; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC RECEPTOR;

ANIMAL CELL; ARTICLE; ASSAY; AUTOMATION; BIOTECHNOLOGY; CALCIUM CELL LEVEL; CALCULATION; COMPUTER; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; FLUOROMETRIC IMAGING PLATE READER; FLUOROMETRY; IC 50; IMAGING SYSTEM; INSTRUMENT; MAMMAL CELL; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ELECTRONICS; FLUORESCENCE; METABOLISM; RAT;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

ANIMALS; CALCIUM; CARBACHOL; FLUORESCENCE; GTP-BINDING PROTEINS; MINIATURIZATION; RATS; RECEPTORS, MUSCARINIC;

EID: 13844286793     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057104264038     Document Type: Article

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