Printing chemical libraries on microarrays for fluid phase nanoliter reactions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 15, 2003, Pages 8721-8726

  Gosalia, Dhaval N ^a,b   Diamond, Scott L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Caspase; Drug discovery; Glycerol; Microfluidics; Thrombin

Indexed keywords

CASPASE; CASPASE 2; CASPASE 4; CASPASE 6; CHYMOTRYPSIN; GLYCEROL; PROTEINASE; THROMBIN; UNCLASSIFIED DRUG;

AEROSOL; ARTICLE; COMBINATORIAL LIBRARY; CONTAMINATION; DNA MICROARRAY; ENZYME SUBSTRATE COMPLEX; HYDROPHOBICITY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSMOLARITY; PRIORITY JOURNAL; SURFACE PROPERTY;

ANIMALS; BIOPHYSICS; CATTLE; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; PROTEIN ARRAY ANALYSIS;

EID: 0041806643     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1530261100     Document Type: Article

References (27)

1. MacBeath, G. & Schreiber, S. L. (2000) Science 289, 1760-1763.
2. Zhu, H., Klemic, J. F., Chang, S., Bertone, P., Casamayor, A., Klemic, K. G., Smith, D., Gerstein, M., Reed, M. A. & Snyder, M. (2000) Nat. Genet. 26, 283-289.
3. Zhu, H. & Snyder, M. (2001) Curr. Opin. Chem. Biol. 5, 40-45.
4. Zhu, H., Bilgin, M., Bangham, R., Hall, D., Casamayor, A., Bertone, P., Lan, N, Jansen, R., Bidlingmaier, S., Houfek, T., et al. (2001) Science 293, 2101-2105.
5. Kuruvilla, F. G., Shamji, A. F., Sternson, S. M., Hergenrother, P. J. & Schreiber, S. L. (2002) Nature 416, 653-657.
6. Houseman, B. T., Huh, J. H., Kron, S. J. & Mrksich, M. (2002) Nat. Biotechnol. 20, 270-274.
7. Arenkov, P., Kukhtin, A., Gemmell, A., Voloshchuk, S., Chupeeva, V. & Mirzabekov, A. (2000) Anal. Biochem. 278, 123-131.
8. Wolcke, J. & Ullman, D. (2001) Drug Discovery Today 6, 637-646.
9. Hertzberg, R. P. & Pope, A. J. (2000) Curr. Opin. Chem. Biol. 4, 445-451.
10. Morita, T., Kato, H., Iwanaga, S., Takada, K., Kimura, T. & Sakakibara, S. (1977) J. Biochem. 82, 1495-1498.
11. Jones, L. J., Upson, R. H., Haugland, R. P., Panchuk-Voloshina, N., Zhou, M. & Haugland, R. P. (1997) Anal. Biochem. 251, 144-152.
12. Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D. & Wong, W. W. (1997) J. Biol. Chem. 272, 9677-9682.
13. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M, Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., et al. (1997) J. Biol. Chem. 272, 17907-17911.
14. Bezeaud, A. & Guillin, M.-C. (1988) J. Biol. Chem. 263, 3576-3581.
15. Zhang, J. H., Chung, T. D. Y. & Oldenburg, K. R. (1999) J. Biomol. Screen. 4, 67-73.
16. Patel, H. V., Fernandes, P. S. & Vyas, K. A. (1990) Indian J. Chem. 29, 1044-1050.
17. Klibanov, A. M. (1997) Trends Biotechnol. 15, 97-101.
18. Zaks, A. & Klibanov, A. M. (1988) J. Biol. Chem. 263, 8017-8021.
19. Xavier, K. A., Shick, K. A., Smith-Gill, S. J. & Willson, R. C. (1997) Biophys. J. 73, 2116-2125.
20. Rariy, R. V. & Klibanov, A. M. (1997) Proc. Natl. Acad. Sci. USA 94, 13520-13523.
21. Pal, P. K. & Gertler, M. M. (1983) Thromb. Res. 29, 175-185.
22. Knubovets, T., Osterhout, J. J., Connolly, P. J. & Klibanov, A. M. (1999) Proc. Natl. Acad. Sci. USA 96, 1262-1267.
23. Burova, T. V., Grinberg, N. V., Grinberg, V. Y., Rariy, R. V. & Klibanov, A. M. (2000) Biochim. Biophys. Acta 1478, 309-317.
24. Backes, B. J., Harris, J. L., Leonetti, F., Craik, C. S. & Ellman, J. A. (2000) Nat. Biotechnol. 18, 187-193.
25. Harris, J. L., Backes, B. J., Leonetti, F., Mahrus, S., Ellman, J. A. & Craik, C. S. (2000) Proc. Natl. Acad. Sci. USA 97, 7754-7759.
26. Salisbury, C. M., Maly, D. J. & Ellman, J. A. (2002) J. Am. Chem. Soc. 124, 14868-14870.
27. Lopez-Otin, C. & Overall, C. M. (2002) Nat. Rev. Mol. Cell Biol. 3, 509-519.