Online magnetic bead dynamic protein-affinity selection coupled to LC-MS for the screening of pharmacologically active compounds

Analytical Chemistry

Volumn 81, Issue 11, 2009, Pages 4263-4270

  Jonker, N ^a   Kretschmer, A ^a   Kool, J ^a   Fernandez, A ^a   Kloos, D ^a   Krabbe, J G ^a   Lingeman, H ^a   Irth, H ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY BEADS; AFFINITY SELECTION; ANALYSIS TIME; ANALYTE; BOUND LIGANDS; DETECTION LIMITS; DYNAMIC PROTEINS; INACTIVE COMPOUNDS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC BEADS; MAGNETIC TRAPPING; PHARMACEUTICAL COMPOUNDS; PHARMACOLOGICALLY ACTIVE COMPOUNDS; PROOF OF PRINCIPLES; PROTEIN-LIGAND COMPLEXES; RECEPTOR LIGANDS; SELECTIVE ISOLATION; STANDARD DEVIATION; TARGET PROTEINS; TRAPPING DEVICES;

CHROMATOGRAPHIC ANALYSIS; COBALT; COMPLEXATION; ELECTROMAGNETIC FIELD EFFECTS; LIGANDS; LIQUID CHROMATOGRAPHY; MAGNETIC FIELDS; MASS SPECTROMETRY; METAL REFINING; MIXTURES;

COBALT COMPOUNDS;

COBALT; COUMESTROL; DICLOFENAC; DIETHYLSTILBESTROL; EPIBATIDINE; EQUOL; ESTRADIOL; NICOTINE; NORETHISTERONE; POLYHISTIDINE TAG; SULFADIMETHOXINE; TESTOSTERONE; TRIMETHOPRIM; WARFARIN;

ARTICLE; DRUG PROTEIN BINDING; DRUG SCREENING; ESTROGEN ACTIVITY; INCUBATION TIME; LIGAND BINDING; LIQUID CHROMATOGRAPHY; MAGNETIC FIELD; MAGNETIC SEPARATION; NONHUMAN; ONLINE ANALYSIS; ONLINE MAGNETIC BEAD DYNAMIC PROTEIN AFFINITY SELECTION COUPLED MASS SPECTROMETRY; PARAMAGNETIC AFFINITY BEAD; PARTICLE SIZE; SIGNAL DETECTION;

CHROMATOGRAPHY, LIQUID; COBALT; EQUIPMENT DESIGN; ESTROGEN RECEPTOR ALPHA; HISTIDINE; HUMANS; LIGANDS; MAGNETICS; MASS SPECTROMETRY; PROTEIN BINDING; PROTEINS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION;

EID: 66349119841     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9000755     Document Type: Article

References (30)

1. Inglese, J.; Johnson, R. L.; Simeonov, A.; Xia, M. H.; Zheng, W.; Austin, C. P.; Auld, D. S. Nat. Chem. Biol. 2007, 3, 466-479.
2. Li, Z. Y.; Mehdi, S.; Patel, I.; Kawooya, J.; Judkins, M.; Zhang, W. H.; Diener, K.; Lozada, A.; Dunnington, D. J. Biomol. Screening 2000, 5, 31-37.
3. Parker, G. J.; Law, T. L.; Lenoch, F. J.; Bolger, R. E. J. Biomol. Screening 2000, 5, 77-88.
4. Yan, B.; Fang, L. L.; Irving, M.; Zhang, S.; Boldi, A. M.; Woolard, F.; Johnson, C. R.; Kshirsagar, T.; Figliozzi, G. M.; Krueger, C. A.; Collins, N. J. Comb. Chem. 2003, 5, 547-559.
5. Van Breemen, R. B.; Huang, C. R.; Nikolic, D.; Woodbury, C. P.; Zhao, Y. Z.; Venton, D. L. Anal. Chem. 1997, 69, 2159-2164.
6. Hage, D. S. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2002, 768, 3-30.
7. Ng, W.; Dai, J. R.; Slon-Usakiewicz, J. J.; Redden, P. R.; Pasternak, A.; Reid, N. J. Biomol. Screening 2007, 12, 167-174.
8. Ferrance, J. P. J. Chromatogr., A 2007, 1165, 86-92.
9. Schlosser, G.; Vekey, K.; Malorni, A.; Pocsfalvi, G. Rapid Commun. Mass Spectrom. 2005, 19, 3307-3314.
10. Choi, Y.; van Breemen, R. B. Comb. Chem. High Throughput Screening 2008, 11, 1-6.
11. Hu, F.; Zhang, H.; Lin, H.; Deng, C.; Zhang, X. J. Am. Soc. Mass Spectrom. 2008, 19, 865-873.
12. Marszałł, M. P.; Moaddel, R.; Kole, S.; Gandhari, M.; Bernier, M.; Wainer, I. W. Anal. Chem. 2008, 80, 7571-7575.
13. Moaddel, R.; Marszall, M. P.; Bighi, F.; Yang, Q.; Duan, X.; Wainer, I. W. Anal. Chem. 2007, 79, 5414-5417.
14. Luckarift, H. R.; Johnson, G. R.; Spain, J. C. J. Chromatogr., B 2006, 843, 310-316.
15. Moaddel, R.; Lu, L. L.; Baynham, M.; Wainer, I. W. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2002, 768, 41-53.
16. Moaddel, R.; Price, G. B.; Juteau, J. M.; Leffak, M.; Wainer, I. W. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2005, 820, 197-203.
17. Yao, N.; Chen, H. M.; Lin, H. Q.; Deng, C. H.; Zhang, X. M. J. Chromatogr., A 2008, 1185, 93-101.
18. Baumann, S.; Ceglarek, U.; Fiedler, G. M.; Lembcke, J.; Leichtle, A.; Thiery, J. Clin. Chem. 2005, 51, 973-980.
19. Zhang, R. Q.; Hirakawa, K.; Seto, D.; Soh, N.; Nakano, K.; Masadome, T.; Nagata, K.; Sakamoto, K.; Imato, T. Talanta 2005, 68, 231-238.
20. Kourilov, V.; Steinitz, M. Anal. Biochem. 2002, 311, 166-170.
21. Hayes, M. A.; Polson, N. A.; Phayre, A. N.; Garcia, A. A. Anal. Chem. 2001, 73, 5896-5902.
22. Odabas, S.; Sayar, F.; Güven, G.; Yanikkaya-Demirel, G.; Piskin, E. J. Chromatogr., B 2007, 861, 74-80.
23. Girault, S.; Chassaing, G.; Blais, J. C.; Brunot, A.; Bolbach, G. Anal. Chem. 1996, 68, 2122-2126.
24. Wang, J. H.; Hansen, E. H.; Miro, M. Anal. Chim. Acta 2003, 499, 139-147.
25. Verpoorte, E. Lab Chip 2003, 3, 60N-68N.
26. Jonker, N.; Kool, J.; Krabbe, J. G.; Retra, K.; Lingeman, H.; Irth, H. J. Chromatogr., A 2008, 1205, 71-77.
27. Eiler, S.; Gangloff, M.; Duclaud, S.; Moras, D.; Ruff, M. Protein Expression Purif. 2001, 22, 165-173.
28. Kozeny, J. Wien. Akad. Wiss. 1927, 136, 271.
29. Carman, P. C. J. Soc. Chem. Ind., London, Trans. Commun. 1938, 57, 225.
30. De Smet, J.; Gzil, P.; Vervoort, N.; Verelst, H.; Baron, G. V.; Desmet, G. J. Chromatogr., A 2005, 1073, 43-51.