HTPS flow cytometry: A novel platform for automated high throughput drug discovery and characterization

Journal of Biomolecular Screening

Volumn 6, Issue 2, 2001, Pages 83-90

  Edwards, Bruce S ^a   Kuckuck, Frederick W ^a   Prossnitz, Erick R ^a   Ransom, John T ^b   Sklar, Larry A ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b Axiom Biotechnologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FORMYLPEPTIDE; LIGAND;

ACCURACY; ARTICLE; ASSAY; AUTOMATION; BONE MARROW CELL; CONTROLLED STUDY; DRUG RESEARCH; DRUG SCREENING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR OCCUPANCY; VALIDATION PROCESS;

AUTOMATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FLOW CYTOMETRY; HUMANS; PEPTIDES; TIME FACTORS; U937 CELLS;

EID: 0035028041     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1089/108705701750160246     Document Type: Article

References (12)

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5. Sheath fluid control to permit stable flow in rapid mix flow cytometry
6. High Throughput Pharmacology System, HTPS® 100. Instrument for automated quantitative analysis of a ligand-receptor interaction based on ligand concentration-dependent functional responses in cells
7. Plug flow cytometry: An automated coupling device for rapid sequential flow cytometric sample analysis
8. Flow cytometry systems for drug discovery and development
9. Undifferentiated U937 cells transfected with chemoattractant receptors: A model system to investigate chemotactic mechanisms and receptor structure/function relationships
10. Cytometric approaches to the study of receptors