Differential role of presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts

Journal of Neuroscience Research

Volumn 84, Issue 4, 2006, Pages 891-902

  Behbahani, Homira ^a   Shabalina, Irina G ^b   Wiehager, Birgitta ^a   Concha, Hérnan ^c   Hultenby, Kjell ^c   Petrovic, Natasa ^b   Nedergaard, Jan ^b   Winblad, Bengt ^a   Cowburn, Richard F ^a   Ankarcrona, Maria ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

secretase; Mitochondrial membrane potential; Presenilin; Respiratory rate

Indexed keywords

GAMMA SECRETASE INHIBITOR; L 685458; PRESENILIN 1; PRESENILIN 2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; BREATHING RATE; CONTROLLED STUDY; DRUG MECHANISM; FIBROBLAST; FLOW CYTOMETRY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; ANIMALS; BENZIMIDAZOLES; CARBOCYANINES; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO; ENZYME INHIBITORS; FIBROBLASTS; FLOW CYTOMETRY; IONOPHORES; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIAL MEMBRANES; OLIGOMYCINS; OXYGEN CONSUMPTION; PRESENILIN-1; PRESENILIN-2;

EID: 33748553081     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20990     Document Type: Article

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