Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

Journal of Biological Chemistry

Volumn 282, Issue 20, 2007, Pages 14708-14718

  James, Andrew M ^a   Sharpley, Mark S ^a   Manas, Abdul Rahman B ^c   Frerman, Frank E ^b   Hirst, Judy ^a   Smith, Robin A J ^c   Murphy, Michael P ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; MITOCHONDRIA; OXIDOREDUCTASES; PHOSPHOLIPID BILAYERS; REACTIVE OXYGEN; TRIPHENYLPHOSPHONIUM CATION; UBIQUINONE MOIETY;

BINDING SITES; COMPLEXATION; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR MODELING; OXIDATIVE STRESS; PERMITTIVITY;

PHOSPHOLIPIDS;

ANTIOXIDANT; ELECTRON TRANSFERRING FLAVOPROTEIN; PHOSPHOLIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE; 10 (6' UBIQUINONYL)DECYLTRIPHENYLPHOSPHONIUM BROMIDE; 10-(6'-UBIQUINONYL)DECYLTRIPHENYLPHOSPHONIUM BROMIDE; DRUG DERIVATIVE; ORGANOPHOSPHORUS COMPOUND; THIOBUTYLTRIPHENYLPHOSPHONIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVE SITE; LIPID BILAYER; MITOCHONDRION; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REDUCTION KINETICS; STEREOSPECIFICITY; ANIMAL; CATTLE; CHEMISTRY; ENZYMOLOGY; HEART MITOCHONDRION; METABOLISM; OXIDATION REDUCTION REACTION;

ANIMALS; ANTIOXIDANTS; CATTLE; ELECTRON TRANSPORT COMPLEX I; LIPID BILAYERS; MITOCHONDRIA, HEART; ORGANOPHOSPHORUS COMPOUNDS; OXIDATION-REDUCTION; PHOSPHOLIPIDS; UBIQUINONE;

EID: 34447558681     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611463200     Document Type: Article

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