-
2
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
Meylan E, Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006 442 : 39 44.
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
3
-
-
8344261590
-
Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed
-
Dinarello CA. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J Endotoxin Res 2004 10 : 201 222.
-
(2004)
J Endotoxin Res
, vol.10
, pp. 201-222
-
-
Dinarello, C.A.1
-
5
-
-
0022235460
-
The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones
-
McKean DJ, Nilson A, Beck BN, Giri J, Mizel SB, Handwerger BS. The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones. J Immunol 1985 135 : 3205 3216.
-
(1985)
J Immunol
, vol.135
, pp. 3205-3216
-
-
McKean, D.J.1
Nilson, A.2
Beck, B.N.3
Giri, J.4
Mizel, S.B.5
Handwerger, B.S.6
-
6
-
-
56149119563
-
Cutting edge: Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
-
Kool M, Petrilli V, De Smedt T, et al. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008 181 : 3755 3759.
-
(2008)
J Immunol
, vol.181
, pp. 3755-3759
-
-
Kool, M.1
Petrilli, V.2
De Smedt, T.3
-
7
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immun 2007 8 : 942 949.
-
(2007)
Nat Immun
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
8
-
-
66949175347
-
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
-
Meng G, Zhang F, Fuss I, Kitani A, Strober W. A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity 2009 30 : 860 874.
-
(2009)
Immunity
, vol.30
, pp. 860-874
-
-
Meng, G.1
Zhang, F.2
Fuss, I.3
Kitani, A.4
Strober, W.5
-
9
-
-
65549154784
-
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
-
Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, Fitzgerald KA. An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe 2009 5 : 487 497.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
Patel, K.4
Hall, B.A.5
Brown, G.D.6
Fitzgerald, K.A.7
-
10
-
-
70349317039
-
Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
-
Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, Sutterwala FS. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J Immunol 2009 183 : 3578 3581.
-
(2009)
J Immunol
, vol.183
, pp. 3578-3581
-
-
Joly, S.1
Ma, N.2
Sadler, J.J.3
Soll, D.R.4
Cassel, S.L.5
Sutterwala, F.S.6
-
11
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009 459 433 436.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
-
12
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza a virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza a virus through recognition of viral RNA. Immunity 2009 30 : 556 565.
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
-
13
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR, et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 2009 30 : 566 575.
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge, J.R.3
-
14
-
-
60549112774
-
Inflammasome recognition of influenza virus is essential for adaptive immune responses
-
Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 2009 206 : 79 87.
-
(2009)
J Exp Med
, vol.206
, pp. 79-87
-
-
Ichinohe, T.1
Lee, H.K.2
Ogura, Y.3
Flavell, R.4
Iwasaki, A.5
-
15
-
-
33745012076
-
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
-
Lara-Tejero M, Sutterwala FS, Ogura Y, Grant EP, Bertin J, Coyle AJ, Flavell RA, Galan JE. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med 2006 203 : 1407 1412.
-
(2006)
J Exp Med
, vol.203
, pp. 1407-1412
-
-
Lara-Tejero, M.1
Sutterwala, F.S.2
Ogura, Y.3
Grant, E.P.4
Bertin, J.5
Coyle, A.J.6
Flavell, R.A.7
Galan, J.E.8
-
16
-
-
0033679111
-
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation
-
Sansonetti PJ, Phalipon A, Arondel J, Thirumalai K, Banerjee S, Akira S, Takeda K, Zychlinsky A. Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity 2000 12 : 581 590.
-
(2000)
Immunity
, vol.12
, pp. 581-590
-
-
Sansonetti, P.J.1
Phalipon, A.2
Arondel, J.3
Thirumalai, K.4
Banerjee, S.5
Akira, S.6
Takeda, K.7
Zychlinsky, A.8
-
17
-
-
1042292574
-
Roles of caspase-1 in Listeria infection in mice
-
Tsuji NM, Tsutsui H, Seki E, Kuida K, Okamura H, Nakanishi K, Flavell RA. Roles of caspase-1 in Listeria infection in mice. Int Immunol 2004 16 : 335 343.
-
(2004)
Int Immunol
, vol.16
, pp. 335-343
-
-
Tsuji, N.M.1
Tsutsui, H.2
Seki, E.3
Kuida, K.4
Okamura, H.5
Nakanishi, K.6
Flavell, R.A.7
-
18
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med 2005 202 : 1043 1049.
-
(2005)
J Exp Med
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
19
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002 10 : 417 426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
20
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 1995 80 : 401 411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
21
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS, Flavell RA. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science (New York, NY) 1995 267 : 2000 2003.
-
(1995)
Science (New York, NY)
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
22
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 24 : 317 327.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
-
23
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 2004 430 : 213 218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
-
24
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009 458 : 509 513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
25
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009 458 : 514 518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
26
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science (New York, NY) 2009 323 : 1057 1060.
-
(2009)
Science (New York, NY)
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
-
27
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immun 2009 10 : 266 272.
-
(2009)
Nat Immun
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
-
28
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 2006 38 : 240 244.
-
(2006)
Nat Genet
, vol.38
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
29
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006 440 : 237 241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
30
-
-
23044452084
-
NACHT-LRR proteins (NLRs) in bacterial infection and immunity
-
Kufer T.A., Fritz J.H., Philpott D.J. NACHT-LRR proteins (NLRs) in bacterial infection and immunity. Trends Microbiol 2005 13 : 381 388.
-
(2005)
Trends Microbiol
, vol.13
, pp. 381-388
-
-
Kufer, T.A.1
Fritz, J.H.2
Philpott, D.J.3
-
31
-
-
52549099416
-
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
-
Lightfield KL, Persson J, Brubaker SW, et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immun 2008 9 : 1171 1178.
-
(2008)
Nat Immun
, vol.9
, pp. 1171-1178
-
-
Lightfield, K.L.1
Persson, J.2
Brubaker, S.W.3
-
32
-
-
4644247731
-
STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: Multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer
-
Leipe DD, Koonin EV, Aravind L. STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer. J Mol Biol 2004 343 : 1 28.
-
(2004)
J Mol Biol
, vol.343
, pp. 1-28
-
-
Leipe, D.D.1
Koonin, E.V.2
Aravind, L.3
-
33
-
-
22144490446
-
The HIN-200 family: More than interferon-inducible genes?
-
Ludlow LE, Johnstone RW, Clarke CJ. The HIN-200 family: more than interferon-inducible genes? Exp Cell Res 2005 308 : 1 17.
-
(2005)
Exp Cell Res
, vol.308
, pp. 1-17
-
-
Ludlow, L.E.1
Johnstone, R.W.2
Clarke, C.J.3
-
34
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006 440 : 228 232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
-
35
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, et al. Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS ONE 2009 4 : e6510.
-
(2009)
PLoS ONE
, vol.4
, pp. 6510
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
-
36
-
-
69549119940
-
Molecular mechanisms involved in inflammasome activation
-
Bryant C., Fitzgerald K.A. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol 2009 19 : 455 464.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 455-464
-
-
Bryant, C.1
Fitzgerald, K.A.2
-
37
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
Suzuki T, Franchi L, Toma C, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 2007 3 : e111.
-
(2007)
PLoS Pathog
, vol.3
, pp. 111
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
-
38
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem 2001 276 : 28309 28313.
-
(2001)
J Biol Chem
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
39
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, et al. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell 2007 25 : 713 724.
-
(2007)
Mol Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
-
40
-
-
33845497181
-
Inflammatory caspases and inflammasomes: Master switches of inflammation
-
Martinon F., Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ 2007 14 : 10 22.
-
(2007)
Cell Death Differ
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
41
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S, Miura M, Jung YK, Zhu H, Li E, Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 1998 92 : 501 509.
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
42
-
-
15644369352
-
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
-
Gu Y, Kuida K, Tsutsui H, et al. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science (New York, NY) 1997 275 : 206 209.
-
(1997)
Science (New York, NY)
, vol.275
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
-
43
-
-
0031004174
-
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
Ghayur T, Banerjee S, Hugunin M, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 1997 386 : 619 623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
-
44
-
-
58149287750
-
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes
-
Lamkanfi M, Kanneganti TD, Van Damme P, et al. Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes. Mol Cell Proteomics 2008 7 : 2350 2363.
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 2350-2363
-
-
Lamkanfi, M.1
Kanneganti, T.D.2
Van Damme, P.3
-
46
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001 29 : 301 305.
-
(2001)
Nat Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
47
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004 20 : 319 325.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
48
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins PN, Lachmann HJ, Aganna E, McDermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 2004 50 : 607 612.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
49
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, et al. Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med 2009 360 : 2416 2425.
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
-
51
-
-
70349402166
-
The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, cross-over pilot study
-
Terkeltaub R, Sundy J, Schumacher HR, et al. The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, cross-over pilot study. Ann Rheum Dis 2009 68 : 1613 1617.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
Sundy, J.2
Schumacher, H.R.3
-
52
-
-
74049105256
-
Pure hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
-
Pascual V, Allantaz F, Patel P, Palucka AK, Chaussabel D, Banchereau J. Pure hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. J Immunol 2009 183 : 5208 5220.
-
(2009)
J Immunol
, vol.183
, pp. 5208-5220
-
-
Pascual, V.1
Allantaz, F.2
Patel, P.3
Palucka, A.K.4
Chaussabel, D.5
Banchereau, J.6
-
53
-
-
47249152715
-
How the study of children with rheumatic diseases identified interferon-alpha and interleukin-1 as novel therapeutic targets
-
Pascual V et al. How the study of children with rheumatic diseases identified interferon-alpha and interleukin-1 as novel therapeutic targets. Immunol Rev 2008 223 : 39 59.
-
(2008)
Immunol Rev
, vol.223
, pp. 39-59
-
-
Pascual, V.1
-
54
-
-
33645119818
-
Beneficial response to anakinra and thalidomide in Schnitzler's syndrome
-
de Koning HD, Bodar EJ, Simon A, van der Hilst JC, Netea MG, van der Meer JW. Beneficial response to anakinra and thalidomide in Schnitzler's syndrome. Ann Rheum Dis 2006 65 : 542 544.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 542-544
-
-
De Koning, H.D.1
Bodar, E.J.2
Simon, A.3
Van Der Hilst, J.C.4
Netea, M.G.5
Van Der Meer, J.W.6
-
56
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2009 11 : 136 140.
-
(2009)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
57
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, Faulenbach M, Vaag A, Volund A, Ehses JA, Seifert B, Mandrup-Poulsen T, Donath MY. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 2007 356 : 1517 1526.
-
(2007)
N Engl J Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
58
-
-
0034679578
-
Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model
-
Monack DM, Hersh D, Ghori N, Bouley D, Zychlinsky A, Falkow S. Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model. J Exp Med 2000 192 : 249 258.
-
(2000)
J Exp Med
, vol.192
, pp. 249-258
-
-
Monack, D.M.1
Hersh, D.2
Ghori, N.3
Bouley, D.4
Zychlinsky, A.5
Falkow, S.6
-
59
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
-
Ray CA, Black RA, Kronheim SR, Greenstreet TA, Sleath PR, Salvesen GS, Pickup DJ. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell 1992 69 : 597 604.
-
(1992)
Cell
, vol.69
, pp. 597-604
-
-
Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
Greenstreet, T.A.4
Sleath, P.R.5
Salvesen, G.S.6
Pickup, D.J.7
-
60
-
-
28844466449
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection
-
Johnston JB, Barrett JW, Nazarian SH, Goodwin M, Ricciuto D, Wang G, McFadden G. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 2005 23 : 587 598.
-
(2005)
Immunity
, vol.23
, pp. 587-598
-
-
Johnston, J.B.1
Barrett, J.W.2
Nazarian, S.H.3
Goodwin, M.4
Ricciuto, D.5
Wang, G.6
McFadden, G.7
-
61
-
-
41849104578
-
Mycobacterium tuberculosis prevents inflammasome activation
-
Master SS, Rampini SK, Davis AS, et al. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host Microbe 2008 3 : 224 232.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 224-232
-
-
Master, S.S.1
Rampini, S.K.2
Davis, A.S.3
-
62
-
-
46649083006
-
Different evolutionary strategies for the origin of caspase-1 inhibitors
-
da Cunha JP, Galante PA, de Souza SJ. Different evolutionary strategies for the origin of caspase-1 inhibitors. J Mol Evol 2008 66 : 591 597.
-
(2008)
J Mol Evol
, vol.66
, pp. 591-597
-
-
Da Cunha, J.P.1
Galante, P.A.2
De Souza, S.J.3
-
63
-
-
37749030247
-
A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins
-
Kersse K., Vanden Berghe T., Lamkanfi M., Vandenabeele P. A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins. Biochem Soc Trans 2007 35 : 1508 1511.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1508-1511
-
-
Kersse, K.1
Vanden Berghe, T.2
Lamkanfi, M.3
Vandenabeele, P.4
-
64
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
Saleh M, Mathison JC, Wolinski MK, et al. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 2006 440 : 1064 1068.
-
(2006)
Nature
, vol.440
, pp. 1064-1068
-
-
Saleh, M.1
Mathison, J.C.2
Wolinski, M.K.3
-
65
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M, Vaillancourt JP, Graham RK, et al. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 2004 429 : 75 9.
-
(2004)
Nature
, vol.429
, pp. 75-9
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
-
66
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production
-
Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc Natl Acad Sci USA 2006 103 : 9982 9987.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
Smith, B.J.6
Kastner, D.L.7
-
67
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
Papin S, Cuenin S, Agostini L, et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ 2007 14 : 1457 1466.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
-
68
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell 2003 11 : 591 604.
-
(2003)
Mol Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
69
-
-
35348934890
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
-
Yu JW, Fernandes-Alnemri T, Datta P, et al. Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. Mol Cell 2007 28 : 214 227.
-
(2007)
Mol Cell
, vol.28
, pp. 214-227
-
-
Yu, J.W.1
Fernandes-Alnemri, T.2
Datta, P.3
-
70
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc Natl Acad Sci USA 2003 100 : 13501 13506.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
71
-
-
29344448820
-
A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis
-
Ferguson PJ, Bing X, Vasef MA, et al. A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis. Bone 2006 38 : 41 7.
-
(2006)
Bone
, vol.38
, pp. 41-7
-
-
Ferguson, P.J.1
Bing, X.2
Vasef, M.A.3
-
72
-
-
33645734214
-
Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease
-
Grosse J, Chitu V, Marquardt A, et al. Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood 2006 107 : 3350 3358.
-
(2006)
Blood
, vol.107
, pp. 3350-3358
-
-
Grosse, J.1
Chitu, V.2
Marquardt, A.3
-
73
-
-
0038682430
-
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation
-
Stehlik C, Krajewska M, Welsh K, Krajewski S, Godzik A, Reed JC. The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation. Biochem J 2003 373 : 101 113.
-
(2003)
Biochem J
, vol.373
, pp. 101-113
-
-
Stehlik, C.1
Krajewska, M.2
Welsh, K.3
Krajewski, S.4
Godzik, A.5
Reed, J.C.6
-
74
-
-
33947219338
-
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC : CCLR interactions
-
Bedoya F, Sandler LL, Harton JA. Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC : CLR interactions. J Immunol 2007 178 : 3837 3845.
-
(2007)
J Immunol
, vol.178
, pp. 3837-3845
-
-
Bedoya, F.1
Sandler, L.L.2
Harton, J.A.3
-
75
-
-
0034194055
-
The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells
-
Young JL, Sukhova GK, Foster D, Kisiel W, Libby P, Schonbeck U. The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells. J Exp Med 2000 191 : 1535 1544.
-
(2000)
J Exp Med
, vol.191
, pp. 1535-1544
-
-
Young, J.L.1
Sukhova, G.K.2
Foster, D.3
Kisiel, W.4
Libby, P.5
Schonbeck, U.6
-
76
-
-
0033568456
-
Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9
-
Annand RR, Dahlen JR, Sprecher CA, et al. Caspase-1 (interleukin-1beta- converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9. Biochem J 1999 342 (Pt 3 655 665.
-
(1999)
Biochem J
, vol.342
, Issue.PART 3
, pp. 655-665
-
-
Annand, R.R.1
Dahlen, J.R.2
Sprecher, C.A.3
-
77
-
-
34548225362
-
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta
-
Greten FR, Arkan MC, Bollrath J, et al. NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 2007 130 : 918 931.
-
(2007)
Cell
, vol.130
, pp. 918-931
-
-
Greten, F.R.1
Arkan, M.C.2
Bollrath, J.3
-
78
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
Bruey JM, Bruey-Sedano N, Luciano F, et al. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell 2007 129 : 45 56.
-
(2007)
Cell
, vol.129
, pp. 45-56
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Luciano, F.3
-
79
-
-
67650421494
-
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
-
Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature 2009 460 : 269 273.
-
(2009)
Nature
, vol.460
, pp. 269-273
-
-
Guarda, G.1
Dostert, C.2
Staehli, F.3
Cabalzar, K.4
Castillo, R.5
Tardivel, A.6
Schneider, P.7
Tschopp, J.8
|