Redox control of exocytosis: Regulatory role of NADPH, thioredoxin, and glutaredoxin

Diabetes

Volumn 54, Issue 7, 2005, Pages 2132-2142

  Ivarsson, Rosita ^a   Quintens, Roel ^b   Dejonghe, Sandra ^c   Tsukamoto, Katsura ^b   In't Veld, Peter ^c   Renström, Erik ^a   Schuit, Frans C ^b  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; GLUTAREDOXIN; INSULIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SNARE PROTEIN; THIOREDOXIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; ELECTRON MICROSCOPY; EXOCYTOSIS; GENE EXPRESSION; HORMONE RELEASE; INSULIN RELEASE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PANCREAS ISLET BETA CELL; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; EXOCYTOSIS; GLUCOSE; HOMEOSTASIS; INSULIN; ISLETS OF LANGERHANS; NADP; OXIDOREDUCTASES; RATS; RNA, MESSENGER; THIOREDOXIN;

EID: 21344456969     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.54.7.2132     Document Type: Article

References (44)

1. Newgard CB, McGarry JD: Metabolic coupling factors in pancreatic beta-cell signal transduction. Annu Rev Biochem 64:689-719, 1995
2. Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M: The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction. J Nutr 130 (Suppl. 2S):299S-304S, 2000
3. Schuit FC, Huypens P, Heimberg H, Pipeleers DG: Glucose sensing in pancreatic β-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus. Diabetes 50:1-11, 2001
4. Ashcroft FM, Harrison DE, Ashcroft SJ: Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 312:446-448, 1984
5. Henquin JC: Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 49:1751-1760, 2000
6. Ammon HP, Abdel-hamid M: Potentiation of the insulin-releasing capacity of tolbutamide by thiols: studies on the isolated perfused pancreas. Naunyn Schmiedebergs Arch Pharmacol 317:262-267, 1981
7. Van De Winkel M, Pipeleers D: Autofluorescence-activated cell sorting of pancreatic islet cells: purification of insulin-containing B-cells according to glucose-induced changes in cellular redox state. Biochem Biophys Res Commun 114:835-842, 1983
8. Kiekens R, In't Veld P, Mahler T, Schuit F, Van De WM, Pipeleers D: Differences in glucose recognition by individual rat pancreatic B cells are associated with intercellular differences in glucose-induced biosynthetic activity. J Clin Invest 89:117-125, 1992
9. Pralong WF, Bartley C, Wollheim CB: Single islet beta-cell stimulation by nutrients: relationship between pyridine nucleotides, cytosolic Ca2+ and secretion. EMBO J 9:53-60, 1990
10. Bennett BD, Jetton TL, Ying G, Magnuson MA, Piston DW: Quantitative g subcellular imaging of glucose metabolism within intact pancreatic islets. J Biol Chem 271:3647-3651, 1996
11. Malaisse WJ, Hutton JC, Kawazu S, Sener A: The stimulus-secretion coupling of glucose-induced insulin release: metabolic effects of menadione in isolated islets. Eur J Biochem 87:121-130, 1978
12. Trus MD, Hintz CS, Weinstein JB, Williams AD, Pagliara AS, Matschinsky FM: A comparison of the effects of glucose and acetylcholine on insulin release and intermediary metabolism in rat pancreatic islets. J Biol Chem 254:3921-3929, 1979
13. Trus M, Warner H, Matschinsky F: Effects of glucose on insulin release and on intermediary metabolism of isolated perifused pancreatic islets from fed and fasted rats. Diabetes 29:1-14, 1980
14. Heimberg H, De Vos A, Vandercammen A, Van Schaftingen E, Pipeleers D, Schuit F: Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport. EMBO J 12:2873-2879, 1993
15. Farfari S, Schulz V, Corkey B, Prentki M: Glucose-regulated anaplerosis and cataplerosis in pancreatic β-cells: possible implication of a pyruvate/ citrate shuttle in insulin secretion. Diabetes 49:718-726, 2000
16. Flamez D, Berger V, Kruhoffer M, Orntoft T, Pipeleers D, Schuit FC: Critical role for cataplerosis via citrate in glucose-regulated insulin release. Diabetes 51:2018-2024, 2002
17. Lu D, Mulder H, Zhao P, Burgess SC, Jensen MV, Kamzolova S, Newgard CB, Sherry AD: 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc Natl Acad Sci U S A 99:2708-2713, 2002
18. Dukes ID, McIntyre MS, Mertz RJ, Philipson LH, Roe MW, Spencer B, Worley JF 3rd: Dependence on NADH produced during glycolysis for beta-cell glucose signaling. J Biol Chem 269:10979-10982, 1994
19. Eto K, Tsubamoto Y, Terauchi Y, Sugiyama T, Kishimoto T, Takahashi N, Yamauchi N, Kubota N, Murayama S, Aizawa T, Akanuma Y, Aizawa S, Kasai H, Yazaki Y, Kadowa M T: Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion. Science 283:981-985, 1999
20. Holmgren A: Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal 2:811-820, 2000
21. Pipeleers DG, in't Veld PA, Van De WM, Maes E, Schuit FC, Gepts W: A new in vitro model for the study of pancreatic A and B cells. Endocrinology 117:806-816, 1985
22. Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y: Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 36:1139-1145, 1993
23. Eliasson L, Ma X, Renstrom E, Barg S, Berggren PO, Galvanovskis J, Gromada J, Jing X, Lundquist I, Salehi A, Sewing S, Rorsman P: SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells. J Gen Physiol 121:181-197, 2003
24. Renstrom E, Eliasson L, Bokvist K, Rorsman P: Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization. J Physiol 494 (Pt 1):41-52, 1996
25. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acid Res 29:e45, 2001
26. Padilla CA, Martinez-Galisteo E, Lopez-Barea J, Holmgren A, Barcena JA: Immunolocalization of thioredoxin and glutaredoxin in mammalian hypophysis. Mol Cell Endocrinol 85:1-12, 1992
27. Lang T, Bruns D, Wenzel D, Riedel D, Holroyd P, Thiele C, Jahn R: SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis. EMBO J 20:2202-2213, 2001
28. Heimberg H, De Vos A, Pipeleers D, Thorens B, Schuit F: Differences in glucose transporter gene expression between rat pancreatic alpha- and beta-cells are correlated to differences in glucose transport but not in glucose utilization. J Biol Chem 270:8971-8975, 1995
29. Detimary P, Dejonghe S, Ling Z, Pipeleers D, Schuit F, Henquin JC: The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets. J Biol Chem 273:33905-33908, 1998
30. Tucker SJ, Ashcroft FM: A touching case of channel regulation: the ATP-sensitive K+ channel. Curr Opin Neurobiol 8:316-320, 1998
31. Fernandes AP, Holmgren A: Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid Redox Signal 6:63-74, 2004
32. Holmgren A: Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione. Proc Natl Acad Sci U S A 73:2275-2279, 1976
33. Lundstrom-Ljung J, Holmgren A: Glutaredoxin accelerates glutathione-dependent folding of reduced ribonuclease A together with protein disulfide-isomerase. J Biol Chem 270:7822-7828, 1995
34. Daily D, Vlamis-Gardikas A, Offen D, Mittelman L, Melamed E, Holmgren A, Barzilai A: Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by activating NF-kappa B via Ref-1. J Biol Chem 276:1335-1344, 2001
35. Song JJ, Lee YJ: Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1. Biochem J 373:845-853, 2003
36. Eisen A, Kiehart DP, Wieland SJ, Reynolds GT: Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs. J Cell Biol 99:1647-1654, 1984
37. Gerst JE: SNARE regulators: matchmakers and matchbreakers. Biochim Biophys Acta 1641:99-110, 2003
38. Shalev A, Pise-Masison CA, Radonovich M, Hoffmann SC, Hirshberg B, Brady JN, Harlan DM: Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway. Endocrinology 143:3695-3698, 2002
39. Minn AH, Hafele C, Shalev A: Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces {beta}-cell apoptosis. Endocrinology 146:2397-2405, 2005
40. Hughes SJ, Faehling M, Thorneley CW, Proks P, Ashcroft FM, Smith PA: Electrophysiological and metabolic characterization of single β-cells and islets from diabetic GK rats. Diabetes 47:73-81, 1998
41. Ward WK, Bolgiano DC, McKnight B, Halter JB, Porte D Jr: Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 74:1318-1328, 1984
42. Maechler P, Wollheim CB: Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402:685-689, 1999
43. MacDonald MJ, Fahien LA: Glutamate is not a messenger in insulin secretion. J Biol Chem 275:34025-34027, 2000
44. Lowry OH: Amplification by enzymatic cycling. Mol Cell Biochem 32:135-146, 1980