-
1
-
-
0027167547
-
The human glutamate dehydrogenase gene family: Gene organization and structural characterization
-
Michaelidis TM, Tzimagiorgis G, Moschonas NK, Papamatheakis J (1993) The human glutamate dehydrogenase gene family: gene organization and structural characterization. Genomics 16:150-160
-
(1993)
Genomics
, vol.16
, pp. 150-160
-
-
Michaelidis, T.M.1
Tzimagiorgis, G.2
Moschonas, N.K.3
Papamatheakis, J.4
-
2
-
-
0027333040
-
L-glutamate dehydrogenases: Distribution, properties and mechanism
-
Hudson RC, Daniel RM (1993) L-glutamate dehydrogenases: distribution, properties and mechanism. Comp Biochem Physiol B 106:767-792
-
(1993)
Comp Biochem Physiol B
, vol.106
, pp. 767-792
-
-
Hudson, R.C.1
Daniel, R.M.2
-
3
-
-
0033779559
-
Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
-
Anderson CM, Swanson RA (2000) Astrocyte glutamate transport: review of properties, regulation, and physiological functions. Glia 32:1-14
-
(2000)
Glia
, vol.32
, pp. 1-14
-
-
Anderson, C.M.1
Swanson, R.A.2
-
4
-
-
0032698449
-
Newer aspects of glutamine/glutamate metabolism: The role of acute pH changes
-
Nissim I (1999) Newer aspects of glutamine/glutamate metabolism: the role of acute pH changes. Am J Physiol 277: F493-F497
-
(1999)
Am J Physiol
, vol.277
-
-
Nissim, I.1
-
5
-
-
0019133275
-
L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase
-
Sener A, Malaisse WJ (1980) L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase. Nature 288:187-189
-
(1980)
Nature
, vol.288
, pp. 187-189
-
-
Sener, A.1
Malaisse, W.J.2
-
6
-
-
0028106823
-
Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release
-
Bryla J, Michalik M, Nelson J, Erecinska M (1994) Regulation of the glutamate dehydrogenase activity in rat islets of Langerhans and its consequence on insulin release. Metabolism 43:1187-1195
-
(1994)
Metabolism
, vol.43
, pp. 1187-1195
-
-
Bryla, J.1
Michalik, M.2
Nelson, J.3
Erecinska, M.4
-
7
-
-
0038422184
-
Regulatory effects of 5′-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets
-
Yang SJ, Huh JW, Kim MJ et al. (2003) Regulatory effects of 5′-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets. Biochimie 85:581-586
-
(2003)
Biochimie
, vol.85
, pp. 581-586
-
-
Yang, S.J.1
Huh, J.W.2
Kim, M.J.3
-
8
-
-
0032493123
-
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene
-
Stanley CA, Lieu YK, Hsu BY et al. (1998) Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. N Engl J Med 338:1352-1357
-
(1998)
N Engl J Med
, vol.338
, pp. 1352-1357
-
-
Stanley, C.A.1
Lieu, Y.K.2
Hsu, B.Y.3
-
9
-
-
0032777882
-
Hyperinsulinism-hyperammonemia syndrome caused by mutant glutamate dehydrogenase accompanied by novel enzyme kinetics
-
Yorifuji T, Muroi J, Uematsu A, Hiramatsu H, Momoi T (1999) Hyperinsulinism-hyperammonemia syndrome caused by mutant glutamate dehydrogenase accompanied by novel enzyme kinetics. Hum Genet 104:476-479
-
(1999)
Hum Genet
, vol.104
, pp. 476-479
-
-
Yorifuji, T.1
Muroi, J.2
Uematsu, A.3
Hiramatsu, H.4
Momoi, T.5
-
10
-
-
0022272444
-
L-Glutamate dehydrogenase from bovine liver
-
Fisher HF (1985) L-Glutamate dehydrogenase from bovine liver. Methods Enzymol 113:16-27
-
(1985)
Methods Enzymol
, vol.113
, pp. 16-27
-
-
Fisher, H.F.1
-
11
-
-
0035937256
-
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation
-
Smith TJ, Peterson PE, Schmidt T, Fang J, Stanley CA (2001) Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. J Mol Biol 307:707-720
-
(2001)
J Mol Biol
, vol.307
, pp. 707-720
-
-
Smith, T.J.1
Peterson, P.E.2
Schmidt, T.3
Fang, J.4
Stanley, C.A.5
-
12
-
-
0034029974
-
Molecular basis and characterization of the hyperinsulinism/ hyperammonemia syndrome: Predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators
-
Stanley CA, Fang J, Kutyna K et al. (2000) Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators. Diabetes 49:667-673
-
(2000)
Diabetes
, vol.49
, pp. 667-673
-
-
Stanley, C.A.1
Fang, J.2
Kutyna, K.3
-
13
-
-
0033540037
-
Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
-
Maechler P, Wollheim CB (1999) Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402:685-689
-
(1999)
Nature
, vol.402
, pp. 685-689
-
-
Maechler, P.1
Wollheim, C.B.2
-
14
-
-
0034602141
-
Glutamate is not a messenger in insulin secretion
-
MacDonald MJ, Fahien LA (2000) Glutamate is not a messenger in insulin secretion. J Biol Chem 275:34025-34027
-
(2000)
J Biol Chem
, vol.275
, pp. 34025-34027
-
-
MacDonald, M.J.1
Fahien, L.A.2
-
15
-
-
0035965364
-
GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells
-
Rubi B, Ishihara H, Hegardt FG, Wollheim CB, Maechler P (2001) GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells. J Biol Chem 276:36391-36396
-
(2001)
J Biol Chem
, vol.276
, pp. 36391-36396
-
-
Rubi, B.1
Ishihara, H.2
Hegardt, F.G.3
Wollheim, C.B.4
Maechler, P.5
-
16
-
-
0037031896
-
The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related
-
Bertrand G, Ishiyama N, Nenquin M, Ravier MA, Henquin JC (2002) The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related. J Biol Chem 277:32883-32891
-
(2002)
J Biol Chem
, vol.277
, pp. 32883-32891
-
-
Bertrand, G.1
Ishiyama, N.2
Nenquin, M.3
Ravier, M.A.4
Henquin, J.C.5
-
17
-
-
0037032447
-
Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells
-
Hoy M, Maechler P, Efanov AM, Wollheim CB, Berggren PO, Gromada J (2002) Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells. FEBS Lett 531:199-203
-
(2002)
FEBS Lett
, vol.531
, pp. 199-203
-
-
Hoy, M.1
Maechler, P.2
Efanov, A.M.3
Wollheim, C.B.4
Berggren, P.O.5
Gromada, J.6
-
18
-
-
0041802723
-
Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH
-
Liu YJ, Cheng H, Drought H, MacDonald MJ, Sharp GW, Straub SG (2003) Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH. Am J Physiol Endocrinol Metab 285: E380-E389
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Liu, Y.J.1
Cheng, H.2
Drought, H.3
MacDonald, M.J.4
Sharp, G.W.5
Straub, S.G.6
-
19
-
-
0033760442
-
Triggering and amplifying pathways of regulation of insulin secretion by glucose
-
Henquin JC (2000) Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 49: 1751-1760
-
(2000)
Diabetes
, vol.49
, pp. 1751-1760
-
-
Henquin, J.C.1
-
20
-
-
0035856942
-
Mitochondrial function in normal and diabetic beta-cells
-
Maechler P, Wollheim CB (2001) Mitochondrial function in normal and diabetic beta-cells. Nature 414:807-812
-
(2001)
Nature
, vol.414
, pp. 807-812
-
-
Maechler, P.1
Wollheim, C.B.2
-
21
-
-
0032933339
-
The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells
-
Miki T, Nagashima K, Seino S (1999) The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells. J Mol Endocrinol 22:113-123
-
(1999)
J Mol Endocrinol
, vol.22
, pp. 113-123
-
-
Miki, T.1
Nagashima, K.2
Seino, S.3
-
22
-
-
0030894850
-
The pancreatic beta-cell as a fuel sensor: An electrophysiologist's viewpoint
-
Rorsman P (1997) The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint. Diabetologia 40:487-495
-
(1997)
Diabetologia
, vol.40
, pp. 487-495
-
-
Rorsman, P.1
-
23
-
-
0033556082
-
Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
-
Lang J (1999) Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Eur J Biochem 259:3-17
-
(1999)
Eur J Biochem
, vol.259
, pp. 3-17
-
-
Lang, J.1
-
24
-
-
0018975576
-
The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets
-
Malaisse WJ, Sener A, Carpinelli AR et al. (1980) The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets. Mol Cell Endocrinol 20:171-189
-
(1980)
Mol Cell Endocrinol
, vol.20
, pp. 171-189
-
-
Malaisse, W.J.1
Sener, A.2
Carpinelli, A.R.3
-
25
-
-
0021320053
-
Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a nonmetabolizable leucine analogue
-
Panten U, Zielmann S, Langer J, Zunkler BJ, Lenzen S (1984) Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a nonmetabolizable leucine analogue. Biochem J 219:189-196
-
(1984)
Biochem J
, vol.219
, pp. 189-196
-
-
Panten, U.1
Zielmann, S.2
Langer, J.3
Zunkler, B.J.4
Lenzen, S.5
-
26
-
-
0027203345
-
Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport
-
Heimberg H, De Vos A, Vandercammen A, Schaftingen E van, Pipeleers D, Schuit F (1993) Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport. EMBO J 12:2873-2879
-
(1993)
EMBO J
, vol.12
, pp. 2873-2879
-
-
Heimberg, H.1
De Vos, A.2
Vandercammen, A.3
Van Schaftingen, E.4
Pipeleers, D.5
Schuit, F.6
-
27
-
-
77955093164
-
Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid
-
Sener A, Malaisse-Lagae F, Malaisse WJ (1981) Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid. Proc Natl Acad Sci USA 78: 5460-5464
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 5460-5464
-
-
Sener, A.1
Malaisse-Lagae, F.2
Malaisse, W.J.3
-
28
-
-
0032806183
-
Glucose regulation of glutaminolysis and its role in insulin secretion
-
Gao ZY, Li G, Najafi H, Wolf BA, Matschinsky FM (1999) Glucose regulation of glutaminolysis and its role in insulin secretion. Diabetes 48:1535-1542
-
(1999)
Diabetes
, vol.48
, pp. 1535-1542
-
-
Gao, Z.Y.1
Li, G.2
Najafi, H.3
Wolf, B.A.4
Matschinsky, F.M.5
-
29
-
-
0037474212
-
Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets
-
Li C, Najafi H, Daikhin Y et al. (2003) Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets. J Biol Chem 278:2853-2858
-
(2003)
J Biol Chem
, vol.278
, pp. 2853-2858
-
-
Li, C.1
Najafi, H.2
Daikhin, Y.3
-
30
-
-
0036865991
-
Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells
-
Maechler P (2002) Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells. Cell Mol Life Sci 59:1803-1818
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 1803-1818
-
-
Maechler, P.1
-
31
-
-
0038540613
-
Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion
-
Broca C, Brennan L, Petit P, Newsholme P, Maechler P (2003) Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion. FEBS Lett 545:167-172
-
(2003)
FEBS Lett
, vol.545
, pp. 167-172
-
-
Broca, C.1
Brennan, L.2
Petit, P.3
Newsholme, P.4
Maechler, P.5
-
32
-
-
0023695196
-
Regulation of insulin release by factors that also modify glutamate dehydrogenase
-
Fahien LA, MacDonald MJ, Kmiotek EH, Mertz RJ, Fahien CM (1988) Regulation of insulin release by factors that also modify glutamate dehydrogenase. J Biol Chem 263:13610-13614
-
(1988)
J Biol Chem
, vol.263
, pp. 13610-13614
-
-
Fahien, L.A.1
MacDonald, M.J.2
Kmiotek, E.H.3
Mertz, R.J.4
Fahien, C.M.5
-
33
-
-
0020317782
-
The stimulus-secretion coupling of amino acid-induced insulin release. Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets
-
Malaisse-Lagae F, Sener A, Garcia-Morales P, Valverde I, Malaisse WJ (1982) The stimulus-secretion coupling of amino acid-induced insulin release. Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets. J Biol Chem 257:3754-3758
-
(1982)
J Biol Chem
, vol.257
, pp. 3754-3758
-
-
Malaisse-Lagae, F.1
Sener, A.2
Garcia-Morales, P.3
Valverde, I.4
Malaisse, W.J.5
-
34
-
-
1542263385
-
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
-
in press
-
Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB, Maechler P (2003) Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology (in press)
-
(2003)
Endocrinology
-
-
Merglen, A.1
Theander, S.2
Rubi, B.3
Chaffard, G.4
Wollheim, C.B.5
Maechler, P.6
-
35
-
-
0026550830
-
Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
-
Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB (1992) Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130:167-178
-
(1992)
Endocrinology
, vol.130
, pp. 167-178
-
-
Asfari, M.1
Janjic, D.2
Meda, P.3
Li, G.4
Halban, P.A.5
Wollheim, C.B.6
-
36
-
-
0027943837
-
Dynamic pacing of cell metabolism by intracellular Ca2+ transients
-
Pralong WF, Spat A, Wollheim CB (1994) Dynamic pacing of cell metabolism by intracellular Ca2+ transients. J Biol Chem 269:27310-27314
-
(1994)
J Biol Chem
, vol.269
, pp. 27310-27314
-
-
Pralong, W.F.1
Spat, A.2
Wollheim, C.B.3
-
37
-
-
0025884056
-
Efficient selection for high-expression transfectants with a novel eukaryotic vector
-
Niwa H, Yamamura K, Miyazaki J (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-199
-
(1991)
Gene
, vol.108
, pp. 193-199
-
-
Niwa, H.1
Yamamura, K.2
Miyazaki, J.3
-
38
-
-
0030070724
-
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome
-
Miyake S, Makimura M, Kanegae Y (1996) Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci USA 93: 1320-1324
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1320-1324
-
-
Miyake, S.1
Makimura, M.2
Kanegae, Y.3
-
39
-
-
0036311083
-
Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas
-
Maechler P, Gjinovci A, Wollheim CB (2002) Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas. Diabetes 51 [Suppl 1]:S99-S102
-
(2002)
Diabetes
, vol.51
, Issue.1 SUPPL.
-
-
Maechler, P.1
Gjinovci, A.2
Wollheim, C.B.3
-
40
-
-
0033600762
-
Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells
-
Maechler P, Jornot L, Wollheim CB (1999) Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells. J Biol Chem 274:27905-27913
-
(1999)
J Biol Chem
, vol.274
, pp. 27905-27913
-
-
Maechler, P.1
Jornot, L.2
Wollheim, C.B.3
-
41
-
-
0035662149
-
An osmotic-sensitive taurine pool is localized in rat pancreatic islet cells containing glucagon and somatostatin
-
Bustamante J, Lobo MV, Alonso FJ et al. (2001) An osmotic-sensitive taurine pool is localized in rat pancreatic islet cells containing glucagon and somatostatin. Am J Physiol Endocrinol Metab 281:E1275-E1285
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Bustamante, J.1
Lobo, M.V.2
Alonso, F.J.3
-
42
-
-
0030926003
-
Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells
-
Maechler P, Kennedy ED, Pozzan T, Wollheim CB (1997) Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells. EMBO J 16:3833-3841
-
(1997)
EMBO J
, vol.16
, pp. 3833-3841
-
-
Maechler, P.1
Kennedy, E.D.2
Pozzan, T.3
Wollheim, C.B.4
-
43
-
-
0032488880
-
Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase
-
Maechler P, Wang H, Wollheim CB (1998) Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase. FEBS Lett 422: 328-332
-
(1998)
FEBS Lett
, vol.422
, pp. 328-332
-
-
Maechler, P.1
Wang, H.2
Wollheim, C.B.3
-
44
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
45
-
-
0026581414
-
Islet cell metabolism is reflected by the MTT (tetrazolium) colorimetric assay
-
Janjic D, Wollheim CB (1992) Islet cell metabolism is reflected by the MTT (tetrazolium) colorimetric assay. Diabetologia 35:482-485
-
(1992)
Diabetologia
, vol.35
, pp. 482-485
-
-
Janjic, D.1
Wollheim, C.B.2
-
46
-
-
0030810982
-
Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells
-
Schuit F, De Vos A, Farfari S et al. (1997) Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells. J Biol Chem 272:18572-18579
-
(1997)
J Biol Chem
, vol.272
, pp. 18572-18579
-
-
Schuit, F.1
De Vos, A.2
Farfari, S.3
-
47
-
-
0037022527
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)
-
Lu D, Mulder H, Zhao P et al. (2002) 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc Natl Acad Sci USA 99:2708-2713
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2708-2713
-
-
Lu, D.1
Mulder, H.2
Zhao, P.3
-
48
-
-
0037163021
-
The key role of anaplerosis and cataplerosis for citric acid cycle function
-
Owen OE, Kalhan SC, Hanson RW (2002) The key role of anaplerosis and cataplerosis for citric acid cycle function. J Biol Chem 277:30409-30412
-
(2002)
J Biol Chem
, vol.277
, pp. 30409-30412
-
-
Owen, O.E.1
Kalhan, S.C.2
Hanson, R.W.3
-
49
-
-
0345700770
-
Characterization of vesicular glutamate transporter in pancreatic alpha- and beta-cells and its regulation by glucose
-
Bai L, Zhang X, Ghishan FK (2003) Characterization of vesicular glutamate transporter in pancreatic alpha-and beta-cells and its regulation by glucose. Am J Physiol Gastrointest Liver Physiol 284:G808-G814
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Bai, L.1
Zhang, X.2
Ghishan, F.K.3
-
50
-
-
0041802735
-
Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells
-
Eto K, Yamashita T, Hirose K et al. (2003) Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells. Am J Physiol Endocrinol Metab 285:E262-E271
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Eto, K.1
Yamashita, T.2
Hirose, K.3
-
51
-
-
0022663535
-
2-Ketoglutarate generation in pancreatic B-cell mitochondria regulates insulin secretory action of amino acids and 2-keto acids
-
Lenzen S, Schmidt W, Rustenbeck I, Panten U (1986) 2-ketoglutarate generation in pancreatic B-cell mitochondria regulates insulin secretory action of amino acids and 2-keto acids. Biosci Rep 6:163-169
-
(1986)
Biosci Rep
, vol.6
, pp. 163-169
-
-
Lenzen, S.1
Schmidt, W.2
Rustenbeck, I.3
Panten, U.4
-
52
-
-
0036894314
-
Glutaminolysis and insulin secretion: From bedside to bench and back
-
Kelly A, Li C, Gao Z, Stanley CA, Matschinsky FM (2002) Glutaminolysis and insulin secretion: from bedside to bench and back. Diabetes 51 [Suppl 3]:S421-S426
-
(2002)
Diabetes
, vol.51
, Issue.3 SUPPL.
-
-
Kelly, A.1
Li, C.2
Gao, Z.3
Stanley, C.A.4
Matschinsky, F.M.5
-
53
-
-
0033788473
-
Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells
-
Maechler P, Antinozzi PA, Wollheim CB (2000) Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells. IUBMB Life 50:27-31
-
(2000)
IUBMB Life
, vol.50
, pp. 27-31
-
-
Maechler, P.1
Antinozzi, P.A.2
Wollheim, C.B.3
-
54
-
-
0027975322
-
Insulinotropic action of glutamic acid dimethyl ester
-
Sener A, Conget I, Rasschaert J et al. (1994) Insulinotropic action of glutamic acid dimethyl ester. Am J Physiol 267: E573-E584
-
(1994)
Am J Physiol
, vol.267
-
-
Sener, A.1
Conget, I.2
Rasschaert, J.3
-
55
-
-
0026688668
-
Glutamate production in islets of Langerhans: Properties of phosphate-activated glutaminase
-
Michalik M, Nelson J, Erecinska M (1992) Glutamate production in islets of Langerhans: properties of phosphate-activated glutaminase. Metabolism 41:1319-1326
-
(1992)
Metabolism
, vol.41
, pp. 1319-1326
-
-
Michalik, M.1
Nelson, J.2
Erecinska, M.3
-
56
-
-
0019904523
-
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine
-
Malaisse WJ, Sener A, Malaisse-Lagae F et al. (1982) The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine. J Biol Chem 257:8731-8737
-
(1982)
J Biol Chem
, vol.257
, pp. 8731-8737
-
-
Malaisse, W.J.1
Sener, A.2
Malaisse-Lagae, F.3
-
57
-
-
0021368641
-
Transamination of 3-phenylpyruvate in pancreatic B-cell mitochondria
-
Lenzen S, Rustenbeck I, Panten U (1984) Transamination of 3-phenylpyruvate in pancreatic B-cell mitochondria. J Biol Chem 259:2043-2046
-
(1984)
J Biol Chem
, vol.259
, pp. 2043-2046
-
-
Lenzen, S.1
Rustenbeck, I.2
Panten, U.3
-
58
-
-
0022347742
-
Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria
-
Lenzen S, Schmidt W, Panten U (1985) Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria. J Biol Chem 260:12629-12634
-
(1985)
J Biol Chem
, vol.260
, pp. 12629-12634
-
-
Lenzen, S.1
Schmidt, W.2
Panten, U.3
-
59
-
-
0036263720
-
A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: Metabolism of L-alanine is important to the regulation of insulin secretion
-
Brennan L, Shine A, Hewage C et al. (2002) A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion. Diabetes 51:1714-1721
-
(2002)
Diabetes
, vol.51
, pp. 1714-1721
-
-
Brennan, L.1
Shine, A.2
Hewage, C.3
-
60
-
-
0345548707
-
13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line
-
Brennan L, Corless M, Hewage C et al. (2003) 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line. Diabetologia 46:1512-1521
-
(2003)
Diabetologia
, vol.46
, pp. 1512-1521
-
-
Brennan, L.1
Corless, M.2
Hewage, C.3
-
61
-
-
0036313624
-
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: Identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase
-
Tanizawa Y, Nakai K, Sasaki T et al. (2002) Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase. Diabetes 51:712-717
-
(2002)
Diabetes
, vol.51
, pp. 712-717
-
-
Tanizawa, Y.1
Nakai, K.2
Sasaki, T.3
-
62
-
-
0034843898
-
Glutamine alimentation in catabolic state
-
Boelens PG, Nijveldt RJ, Houdijk AP, Meijer S, Leeuwen PA van (2001) Glutamine alimentation in catabolic state. J Nutr 131 [Suppl]:2569S-2577S
-
(2001)
J Nutr
, vol.131
, Issue.SUPPL.
-
-
Boelens, P.G.1
Nijveldt, R.J.2
Houdijk, A.P.3
Meijer, S.4
Van Leeuwen, P.A.5
-
63
-
-
0026236051
-
Effect of exercise on amino acid concentrations in skeletal muscle and plasma
-
Henriksson J (1991) Effect of exercise on amino acid concentrations in skeletal muscle and plasma. J Exp Biol 160: 149-165
-
(1991)
J Exp Biol
, vol.160
, pp. 149-165
-
-
Henriksson, J.1
-
64
-
-
0033431775
-
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells
-
Ishihara H, Wang H, Drewes LR, Wollheim CB (1999) Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells. J Clin Invest 104:1621-1629
-
(1999)
J Clin Invest
, vol.104
, pp. 1621-1629
-
-
Ishihara, H.1
Wang, H.2
Drewes, L.R.3
Wollheim, C.B.4
-
65
-
-
0037221769
-
Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release
-
Otonkoski T, Kaminen N, Ustinov J, Lapatto R, Meissner T, Mayatepek E, Kere J, Sipila I (2003) Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release. Diabetes 52:199-204
-
(2003)
Diabetes
, vol.52
, pp. 199-204
-
-
Otonkoski, T.1
Kaminen, N.2
Ustinov, J.3
Lapatto, R.4
Meissner, T.5
Mayatepek, E.6
Kere, J.7
Sipila, I.8
|