Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion

Journal of Biological Chemistry

Volumn 282, Issue 43, 2007, Pages 31592-31600

  Joseph, Jamie W ^a   Odegaard, Matthew L ^a   Ronnebaum, Sarah M ^a   Burgess, Shawn C ^b   Muehlbauer, Jeffrey ^a   Sherry, A Dean ^b   Newgard, Christopher B ^a,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Duke Independence Park Facility   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION (PROCESS); FATTY ACIDS; GLUCOSE; INSULIN; RNA; SYNTHESIS (CHEMICAL); VIRUSES;

GLUCOSE CARBONS; HYDROXYCITRATE (HC); INSULINOMA CELLS;

ENZYME KINETICS;

ADENOSINE TRIPHOSPHATE CITRATE LYASE; CERULENIN; FATTY ACID SYNTHASE; GLUCOSE; HYDROXYCITRIC ACID; MALONYL COENZYME A; MESSENGER RNA; OXALOACETIC ACID; PYRUVIC ACID; SMALL INTERFERING RNA; SODIUM CHLORIDE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REPRESSION; INSULIN RELEASE; INSULINOMA; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ADENOVIRIDAE; ANIMALS; ATP CITRATE (PRO-S)-LYASE; CARBON ISOTOPES; CELL LINE, TUMOR; FATTY ACID SYNTHETASE COMPLEX; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; MALE; PANCREATIC NEOPLASMS; PYRUVIC ACID; RATS; RATS, WISTAR; RNA, MESSENGER; RNA, SMALL INTERFERING; SODIUM CHLORIDE;

ADENOVIRIDAE; RATTUS;

EID: 35748952524     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706080200     Document Type: Article

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