Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation

American Journal of Physiology - Endocrinology and Metabolism

Volumn 286, Issue 2 49-2, 2004, Pages

  Anno, Takatoshi ^a   Uehara, Shunsuke ^b   Katagiri, Hideki ^c   Ohta, Yasuharu ^a   Ueda, Kohei ^a   Mizuguchi, Hiroyuki ^d   Moriyama, Yoshinori ^b   Oka, Yoshitomo ^c   Tanizawa, Yukio ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Hyperinsulinism hyperammonemia syndrome; Hypoglycemia; Islet of Langerhans

Indexed keywords

2 OXOGLUTARIC ACID; GLUCOSE; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLUTAMINE; INSULIN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CITRIC ACID CYCLE; CONTROLLED STUDY; DEAMINATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HYPERAMMONEMIA; HYPERINSULINISM; HYPERINSULINISM HYPERAMMONEMIA SYNDROME; INSULIN RELEASE; INSULINOMA; MOUSE; NONHUMAN; OXIDATION; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SYNDROME;

EID: 0942298242     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00380.2003     Document Type: Article

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