Switch to anaerobic glucose metabolism with NADH accumulation in the β-cell model of mitochondrial diabetes: Characteristics of βHC9 cells deficient in mitochondrial DNA transcription

Journal of Biological Chemistry

Volumn 277, Issue 44, 2002, Pages 41817-41826

  Noda, Mitsuhiko ^a,b,c,d   Yamashita, Shigeo ^b,d   Takahashi, Noriko ^b,d   Eto, Kazuhiro ^b,d   Shen, Lin Ming ^b,d   Izumi, Kazuo ^b,d   Daniel, Samira ^b,d   Tsubamoto, Yoshiharu ^b,d   Nemoto, Tomomi ^b,d   Iino, Masamitsu ^b,d   Kasai, Haruo ^b,d   Sharp, Geoffrey W G ^b,d   Kadowaki, Takashi ^b,d,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b Cornell University ^*  (United States)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e INSTITUTE FOR ADULT DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOLOGICAL MEMBRANES; CALCIUM; CARBOXYLIC ACIDS; DISEASES; DNA; FLUORESCENCE; GENES; GLUCOSE; INSULIN; METABOLISM; MICROSCOPIC EXAMINATION; MUTAGENESIS; OXIDATION;

ELECTRON TRANSPORT SYSTEMS;

CELLS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM; CELL NUCLEUS DNA; ETHIDIUM BROMIDE; GLIBENCLAMIDE; INSULIN; LACTIC ACID; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANAEROBIC GLYCOLYSIS; ANIMAL CELL; ARTICLE; AUTOFLUORESCENCE; CALCIUM CELL LEVEL; CITRIC ACID CYCLE; CONTROLLED STUDY; DIABETES MELLITUS; DNA TRANSCRIPTION; ELECTRON TRANSPORT; GENE MUTATION; GLUCOSE OXIDATION; GLUCOSE UTILIZATION; INSULIN RELEASE; LASER MICROSCOPY; MEMBRANE POTENTIAL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANAEROBIOSIS; ANIMALS; CALCIUM; CELL COUNT; CELLS, CULTURED; DIABETES MELLITUS; DNA, MITOCHONDRIAL; ETHIDIUM; GLUCOSE; GLYBURIDE; INSULIN; ISLETS OF LANGERHANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; NAD; TRANSCRIPTION, GENETIC;

ANIMALIA; MURINAE;

EID: 0036829678     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207690200     Document Type: Article

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