Overexpression of a Modified Human Malonyl-CoA Decarboxylase Blocks the Glucose-induced Increase in Malonyl-CoA Level but Has No Impact on Insulin Secretion in INS-1-derived (832/13) β-Cells

Journal of Biological Chemistry

Volumn 276, Issue 9, 2001, Pages 6479-6484

  Mulder, Hindrik ^a   Lu, Danhong ^a   Finley IV, John ^c   An, Jie ^a   Cohen, Jonathan ^a,b   Antinozzi, Peter A ^a   McGarry, J Denis ^a   Newgard, Christopher B ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; ENZYMES; FATTY ACIDS; GLUCOSE; INSULIN;

EXOCYTOSIS;

CELLS;

CARBON 14; CARBOXYLYASE; COMPLEMENTARY DNA; FATTY ACID; GLUCOSE; INSULIN; MALONYL COENZYME A; PALMITIC ACID; DIAZOXIDE; MALONYL COENZYME A DECARBOXYLASE; MALONYL-COA DECARBOXYLASE; TRIACSIN C; TRIAZENE DERIVATIVE;

ADENOVIRUS; ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; FATTY ACID OXIDATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INSULIN RELEASE; ISOTOPE LABELING; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; VIRUS RECOMBINANT; BIOSYNTHESIS; CELL LINE; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PANCREAS ISLET; PHYSIOLOGY; SECRETION;

ADENOVIRIDAE; ANSER SP.;

ADENOVIRIDAE; CARBOXY-LYASES; CELL LINE; DIAZOXIDE; FATTY ACIDS; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALONYL COENZYME A; OXIDATION-REDUCTION; TRIAZENES;

EID: 0035794185     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010364200     Document Type: Article

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