Non-animal sensitization testing: State-of-the-art

Critical Reviews in Toxicology

Volumn 40, Issue 5, 2010, Pages 389-404

  Vandebriel, Rob J ^a   Loveren, Henk Van ^a,b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

3D reconstructed epidermal model; Alternative testing; Gene expression profiling; Integrated testing; Oxidative stress response; Peptide reactivity; QSAR; Sensitization; Signaling pathway

Indexed keywords

ANTIOXIDANT;

ASTHMA; CELL TYPE; COCULTURE; COMPUTER MODEL; CONTACT ALLERGY; DENDRITIC CELL; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIZATION; EXPERIMENTAL MODEL; GENETIC ANALYSIS; GENOMICS; HUMAN; IN VIVO STUDY; KERATINOCYTE; MEDICAL SOCIETY; NONHUMAN; OXIDATIVE STRESS; PARAMETER; PATCH TEST; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TOXICOLOGY;

ANIMAL TESTING ALTERNATIVES; ARTEMISININS; COSMETICS; EUROPEAN UNION; PEPTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 77951463627     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408440903524262     Document Type: Review

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