In vitro primary sensitization of hapten-specific T cells by cultured human epidermal Langerhans cells - A screening predictive assay for contact sensitizers

Clinical and Experimental Allergy

Volumn 26, Issue 5, 1996, Pages 563-570

  Krasteva, M ^a   Peguet Navarro, J ^a   Moulon, C ^a   Courtellemont, P ^b   Redziniak, G ^b   Schmitt, D ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b Centre de Recherche PCD   (France)

Author keywords

Alternative test methods; Contact allergens; Contact sensitivity; in vitro primary sensitization; Irritants; Langerhans cell

Indexed keywords

CITRONELLAL; CONTACT ALLERGEN; COUMARIN; DODECYL SULFATE SODIUM; FLUORESCEIN ISOTHIOCYANATE; TRINITROPHENYL;

ADULT; ARTICLE; CONTACT SENSITIZATION; HUMAN; HUMAN CELL; LANGERHANS CELL; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SENSITIZATION; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

COUMARINS; DERMATITIS, CONTACT; DIAZONIUM COMPOUNDS; FLUORESCEIN-5-ISOTHIOCYANATE; HAPTENS; HUMANS; IMMUNIZATION; LANGERHANS CELLS; LYMPHOCYTE ACTIVATION; PHENYLENEDIAMINES; PYRIDINES; SODIUM DODECYL SULFATE; T-LYMPHOCYTES; TERPENES; TRINITROBENZENES;

EID: 0029973034     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1996.tb00577.x     Document Type: Article

References (41)

1. Kripke ML, Munn CG, Jeevan A, Tang JM, Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J Immunol 1990; 145:2833-9.
2. Kligman AM. The identification of contact allergens by human assay. III. The maximization test: a procedure for screening and rating contact sensitizers. J Invest Dermatol 1966; 47:393-409.
3. Magnusson B, Kligman AM. The identification of contact allergens by animal assay. The guinea pig maximization test. J Invest Dermatol 1969; 52:268-76.
4. OECD guideline for testing of chemicals No 406, Skin sensitization, adopted by the Council on 17th July 1992. Organization for Economic Cooperation and Development, Paris.
5. EEC Commission Directive of 31 July 1992 adapting to technical progress for the 17th time, Council Directive 67/ 548/EEC. Official Journal of the European Communities L383A 35, 192: 131-6.
6. Seldin MF, Rich RR. Human immune responses to hapten-conjugated cells. I. Primary and secondary proliferative responses in vitro. J Exp Med 1978; 147:167-178.
7. Charmot D, Mawas C. The in vitro cellular response of human lymphocytes to trinitrophenylated autologous cells: HLA D restriction of proliferation but apparent absence of HLA restriction of cytolysis. Eur J Immunol 1979: 9:723-8.
8. Hauser C, Katz SI. Generation and characterization of T-helper cells by primary in vitro sensitization using Langerhans cells. Immunol Rev 1990; 117:67-72.
9. Moulon C, Péguet-Navarro J, Courtellemont P, Redziniak G, Schmitt D. In vitro primary sensitization and restimulation of hapten-specific T cells by fresh and cultured human epidermal Langerhans' cells. Immunology 1993; 80:373-9.
10. Péguet-Navarro J, Dalbiez-Gauthier C, Dezutter-Dambuyant C, Schmitt D. Dissection of human Langerhans cells' allostimulatory function: the need for an activation step for full development of accessory function. Eur J Immunol 1993; 23:376-81.
11. Shearer GM. Cell mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes. Eur J Immunol 1974; 4: 527-32.
12. Krasteva M, Nicolas JF, Chabeau G et al. Dissociation of allergenic and immunogenic functions in contact sensitivity to para-phenylenediamine. Int Arch Allergy Immunol 1993; 102:200-4.
13. Basketter D, Dooms-Goossens A, Karlberg AT, Lepoittevin JP. The chemistry of contact allergy: why is a molecule allergenic? Contact Dermatitis 1995; 32:65-73.
14. Barbier A, Rizova E, Stampf JL et al. Development of a predictive in vitro test for detection of sensitizing compounds (European Bridge project). In: (Rougier A, Goldberg A, Maibach HI, eds.) Alternative methods in toxicology, vol. 10. In vitro skin toxicology. Irritation, phototoxicity, sensitization. N. York: Mary Ann Liebert, Inc. Publishers, 1994: 341-50.
15. Kimber I. Chemical allergy: Cellular and molecular mechanisms and novel approaches to predictive testing. Toxicol. 1994; 8:987-90.
16. Silberberg-Sinakin I, Gigli I, Baer RL, Thorbecke GJ. Langerhans cells: role in contact hypersensitivity and relationship to lymphoid dendritic cells and to macrophages. Immunol Rev 1980; 53:203-12.
17. Steinman RM. The dendritic cell system and its role in immunogenicity. Ann Rev Immunol 1991; 9:271-8.
18. Schuler G, Steinman RM. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp Med 1985; 161:526-78.
19. Romani N, Lenz A, Glassei H, Stossel H, Stanzl U, Majdic O, Fritsch P, Schuler G. Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and functions. J Invest Dermatol 1989; 93:600-6.
20. Symington FW, Brady W, Linsley PS. Expression and function of B7 on human epidermal Langerhans cells. J Immunol 1993; 150:1286-92.
21. Streilein JW, Grammer SF. In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes. J Immunol 1989; 143:3925-32.
22. Witmer-Pack MD, Oliver W, Valinsky J, Schuler G, Steinman RM. Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J Exp Med 1987; 166: 1484-98.
23. Hauser C, Katz SI. Generation and characterization of T-helper cells by primary in vitro sensitization using Langerhans cell. Immunol Rev 1990; 117:67-71.
24. Macatonia SE, Edwards AJ, Knight SC. Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate. Immunology 1986; 59:509-14.
25. Hauser C, Yokoyama WM, Katz SI. Characterization of primary T helper cell activation and T helper cell lines stimulated by hapten-modified cultured Langerhans cells. J Invest Dermatol 1989; 93:649-55.
26. Marzulli FN, Maibach HI. The use of graded concentrations in studying skin sensitizers: experimental contact sensitization in man. Food Cosm Toxicol 1974; 12:219-27.
27. Goodwin BFJ, Crevel RWR, Johnson AW. A comparison of three guinea pig sensitization procedures for the detection of 19 reported human contact sensitizers. Contact Dermatitis 1981; 7:248-58.
28. Basketter DA, Scholes EW. Comparison of the local lymph node assay with the guinea pig maximization test for the detection of a range of contact allergens. Food Chem Toxicol 1992; 30:65-9.
29. Dupuis G, Benezra C. Allergic contact dermatitis to simple chemicals. New York: Dekker, 1982.
30. Basketter DA, Liden C. Further investigation of the prohapten concept: Reactions to benzene derivatives in man. Contact Dermatitis 1992; 27:90-7.
31. Opdyke DLJ. Monographs on fragrance raw materials. Food Cosm Toxicol 1975; 13:681-923.
32. Opdyke DLJ. Monographs on fragrance raw materials. Food Cosm Toxicol 1974; 13:517-93.
33. Steltenkamp KJ, Booman KA, Dorsky J, King TO, Rothenstein AS, Schwoeppe EA, Sedlac RI, Smith THF, Thompson GR. Hydroxycitronellal: A survey of consumer patch test sensitization. Food Cosm Toxicol 1980; 18:407-12.
34. Ford RA, Api AM, Suskind RR. Allergic contact sensitization potential of hydroxycitronellal in humans. Food Chem Toxicol 1988; 26:921-26.
35. Widmer J, Eisner P, Burg G. Skin irritant reactivity following experimental cumulative irritant contact dermatitis. Contact Dermatitis 1994; 30:35-42.
36. Brand CU, Hunziker Th, Schaffner Th, Limat A, Gerber HA, Braathen LR. Activated immunocompetent cells in human skin lymph derived from irritant contact dermatitis: an immunomorphological study. Br J Dermatol 1994; 132: 39-45.
37. Basketter DA, Scholes EW, Kimber I. The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test. Food Chem Toxicol 1994; 32:543-7.
38. De Silva O, Perez MJ, Dossou KG. The ex-vivo local lymph node assay (LLNA). In: Rougier A, Goldberg A, Maibach HI, eds. Alternative methods in toxicology, vol. 10. In vitro skin toxicology. Irritation, phototoxicity, sensitization. N. York: Mary Ann Liebert, Inc. publishers, 1994: 373-81.
39. Montelius J, Wahlquist H, Boman A, Fernstrôm P, Grabergs L, Wahlberg JE. Experience with the murine local lymph node assay: Inability to discriminate between allergens and irritants. Acta Derm Venereol 1994; 74:22-7.
40. Cumberbatch M, Scott RC, Basketter DA, Scholes EW, Hilton J, Dearman RJ, Kimber I. Influence of sodium dodecyl sulfate on 2,4-dinitrochlorbenzene-induced lymph node activation. Toxicology 1993; 77:181-91.
41. Cumberbatch M, Kimber I. Tumour necrosis factor-α is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization. Immunology 1995; 84:31-5.