Read-across to rank skin sensitization potential: Subcategories for the Michael acceptor domain

Contact Dermatitis

Volumn 60, Issue 1, 2009, Pages 21-31

  Schultz, Terry Wayne ^a,b   Rogers, Kathryn ^a   Aptula, Aynur Osman ^c  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OECD   (France)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

Categories; Glutathione reactivity; LLNA; Michael acceptors; Skin sensitization; Subcategories

Indexed keywords

2 AMINOPHENOL; 2 METHOXY 4 METHYL PHENOL; 2 NITRO 4 PHENYLENEDIAMINE; 3 AMINOPHENOL; 5 METHYLEUGENOL; 6 METHYLCOUMARIN; 6 METHYLISOEUGENOL; ACRYLIC ACID 2 HYDROXYETHYL ESTER; ACRYLIC ACID DERIVATIVE; ACRYLIC ACID ETHYL ESTER; BENZOQUINONE; CARBONYL DERIVATIVE; CINNAMALDEHYDE; CINNAMYL ALCOHOL; COUMARIN; DIAMINE DERIVATIVE; DIHYDROEUGENOL; DODECYL GALLATE; ESTRAGOLE; ETHYLENE GLYCOL DIMETHYACRYLATE; GLUTATHIONE; HYDROQUINONE; ISOEUGENOL; ISOPROPYL ISOEUGENOL; MALEIC ACID DIETHYL ESTER; PHENOL DERIVATIVE; PHENYLENEDIAMINE; RESORCINOL; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; COMPUTER MODEL; LYMPH NODE; MICHAEL ADDITION; PROTEIN BINDING; SKIN SENSITIZATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CATALYTIC DOMAIN; DERMATITIS, ALLERGIC CONTACT; DERMATITIS, IRRITANT; DISEASE MODELS, ANIMAL; GLUTATHIONE; GUINEA PIGS; HUMANS; IMMUNIZATION; IRRITANTS; LOCAL LYMPH NODE ASSAY; MICE; MODELS, CHEMICAL; PROTEIN BINDING; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SKIN IRRITANCY TESTS; TOXICITY TESTS;

EID: 58149293575     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2008.01473.x     Document Type: Article

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