-
1
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2: 38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
10644270846
-
Tumor hypoxia: Causative factors, compensatory mechanisms, and cellular response
-
Vaupel P, Harrison L. Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response. Oncologist 2004; 9(5): 4-9.
-
(2004)
Oncologist
, vol.9
, Issue.5
, pp. 4-9
-
-
Vaupel, P.1
Harrison, L.2
-
3
-
-
84966192535
-
The histological structure of some human lung cancers and the possible implications for radiotherapy
-
Thomlinson RH, Gray LH. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955; 9: 539-549
-
(1955)
Br J Cancer
, vol.9
, pp. 539-549
-
-
Thomlinson, R.H.1
Gray, L.H.2
-
4
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 721-732
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
5
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510-5514
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
6
-
-
18444368709
-
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL
-
Hon WC, Wilson MI, Harlos K, et al. Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature 2002; 417: 975-978
-
(2002)
Nature
, vol.417
, pp. 975-978
-
-
Hon, W.C.1
Wilson, M.I.2
Harlos, K.3
-
7
-
-
0035918213
-
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP
-
Yamashita K, Discher DJ, Hu J, Bishopric NH, Webster KA. Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP. J Biol Chem 2001; 276: 12645-12653
-
(2001)
J Biol Chem
, vol.276
, pp. 12645-12653
-
-
Yamashita, K.1
Discher, D.J.2
Hu, J.3
Bishopric, N.H.4
Webster, K.A.5
-
8
-
-
33751169387
-
Hypoxia-inducible factor-1 (HIF-1)
-
Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 2006; 70: 1469-1480
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1469-1480
-
-
Ke, Q.1
Costa, M.2
-
9
-
-
0035105565
-
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
-
Wykoff CC, Beasley N, Watson PH, et al. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol 2001; 158: 1011-1019
-
(2001)
Am J Pathol
, vol.158
, pp. 1011-1019
-
-
Wykoff, C.C.1
Beasley, N.2
Watson, P.H.3
-
10
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wykoff CC, Beasley NJ, Watson PH, et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000; 60: 7075-7083
-
(2000)
Cancer Res
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.2
Watson, P.H.3
-
11
-
-
0035937715
-
Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia
-
Chen C, Pore N, Behrooz A, Ismail-Beigi F, Maity A. Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia. J Biol Chem 2001; 276: 9519-9525
-
(2001)
J Biol Chem
, vol.276
, pp. 9519-9525
-
-
Chen, C.1
Pore, N.2
Behrooz, A.3
Ismail-Beigi, F.4
Maity, A.5
-
12
-
-
41049084437
-
Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc
-
Richardson SM, Knowles R, Tyler J, Mobasheri A, Hoyland JA. Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc. Histochem Cell Biol 2008; 129: 503-511
-
(2008)
Histochem Cell Biol
, vol.129
, pp. 503-511
-
-
Richardson, S.M.1
Knowles, R.2
Tyler, J.3
Mobasheri, A.4
Hoyland, J.A.5
-
13
-
-
67650480092
-
mTOR and HIF- 1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
-
Shackelford DB, Vasquez DS, Corbeil J, et al. mTOR and HIF- 1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome. Proc Natl Acad Sci USA 2009; 106: 11137-11142
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11137-11142
-
-
Shackelford, D.B.1
Vasquez, D.S.2
Corbeil, J.3
-
14
-
-
33644939782
-
Hypoxia-inducible transcription factor- 1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway
-
Luo F, Liu X, Yan N, et al. Hypoxia-inducible transcription factor- 1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway. BMC Cancer 2006; 6: 26.
-
(2006)
BMC Cancer
, vol.6
, pp. 26
-
-
Luo, F.1
Liu, X.2
Yan, N.3
-
15
-
-
35348909046
-
Hypoxia inducible factor-1 independent pathways in tumor angiogenesis
-
Mizukami Y, Kohgo Y, Chung DC. Hypoxia inducible factor-1 independent pathways in tumor angiogenesis. Clin Cancer Res 2007; 13: 5670-5674
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5670-5674
-
-
Mizukami, Y.1
Kohgo, Y.2
Chung, D.C.3
-
16
-
-
34250221735
-
Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-1alpha in human glioma in vitro and in vivo
-
Said HM, Hagemann C, Staab A, et al. Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-1alpha in human glioma in vitro and in vivo. Radiother Oncol 2007; 83: 398-405.
-
(2007)
Radiother Oncol
, vol.83
, pp. 398-405
-
-
Said, H.M.1
Hagemann, C.2
Staab, A.3
-
17
-
-
0030069889
-
Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
-
Overgaard J, Horsman MR. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 1996; 6: 10-21.
-
(1996)
Semin Radiat Oncol
, vol.6
, pp. 10-21
-
-
Overgaard, J.1
Horsman, M.R.2
-
20
-
-
34547666796
-
A review of the interaction among dietary antioxidants and reactive oxygen species
-
Seifried HE, Anderson DE, Fisher EI, Milner JA. A review of the interaction among dietary antioxidants and reactive oxygen species. J Nutr Biochem 2007; 18: 567-579
-
(2007)
J Nutr Biochem
, vol.18
, pp. 567-579
-
-
Seifried, H.E.1
Anderson, D.E.2
Fisher, E.I.3
Milner, J.A.4
-
21
-
-
0347419309
-
Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro
-
Koch S, Mayer F, Honecker F, Schittenhelm M, Bokemeyer C. Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro. Br J Cancer 2003; 89: 2133-2139
-
(2003)
Br J Cancer
, vol.89
, pp. 2133-2139
-
-
Koch, S.1
Mayer, F.2
Honecker, F.3
Schittenhelm, M.4
Bokemeyer, C.5
-
22
-
-
33749556704
-
Chronic hypoxia promotes hypoxia-inducible factor-1alpha-dependent resistance to etoposide and vincristine in neuroblastoma cells
-
Hussein D, Estlin EJ, Dive C, Makin GW. Chronic hypoxia promotes hypoxia-inducible factor-1alpha-dependent resistance to etoposide and vincristine in neuroblastoma cells. Mol Cancer Ther 2006; 5: 2241-2250
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2241-2250
-
-
Hussein, D.1
Estlin, E.J.2
Dive, C.3
Makin, G.W.4
-
23
-
-
0028061116
-
Hypoxia-induced resistance to doxorubicin and methotrexate in human melanoma cell lines in vitro
-
Sanna K, Rofstad EK. Hypoxia-induced resistance to doxorubicin and methotrexate in human melanoma cell lines in vitro. Int J Cancer 1994; 58: 258-262
-
(1994)
Int J Cancer
, vol.58
, pp. 258-262
-
-
Sanna, K.1
Rofstad, E.K.2
-
24
-
-
33748458071
-
Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene
-
Song X, Liu X, Chi W, et al. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene. Cancer Chemother Pharmacol 2006; 58: 776-784
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 776-784
-
-
Song, X.1
Liu, X.2
Chi, W.3
-
26
-
-
0034743861
-
Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
-
Vaupel P, Kelleher DK, Hockel M. Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001; 28: 29-35.
-
(2001)
Semin Oncol
, vol.28
, pp. 29-35
-
-
Vaupel, P.1
Kelleher, D.K.2
Hockel, M.3
-
28
-
-
0026022660
-
Pathophysiological approaches to identifying tumor hypoxia in patients
-
Mueller-Klieser W, Schlenger KH, Walenta S, et al. Pathophysiological approaches to identifying tumor hypoxia in patients. Radiother Oncol 1991; 20 (1): 21-28
-
(1991)
Radiother Oncol
, vol.20
, Issue.1
, pp. 21-28
-
-
Mueller-Klieser, W.1
Schlenger, K.H.2
Walenta, S.3
-
30
-
-
16244399521
-
Tumor oxygenation status as a prognostic marker
-
Menon C, Fraker DL. Tumor oxygenation status as a prognostic marker. Cancer Lett 2005; 221: 225-235
-
(2005)
Cancer Lett
, vol.221
, pp. 225-235
-
-
Menon, C.1
Fraker, D.L.2
-
31
-
-
8544273661
-
Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker
-
Nozue M, Lee I, Yuan F, et al. Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker. J Surg Oncol 1997; 66: 30-38
-
(1997)
J Surg Oncol
, vol.66
, pp. 30-38
-
-
Nozue, M.1
Lee, I.2
Yuan, F.3
-
33
-
-
1842412515
-
Biochemical and molecular consequences of massive mitochondrial gene loss in different tissues of a mutant strain of Drosophila subobscura
-
Beziat F, Touraille S, Debise R, et al. Biochemical and molecular consequences of massive mitochondrial gene loss in different tissues of a mutant strain of Drosophila subobscura. J Biol Chem 1997; 272: 22583-22590
-
(1997)
J Biol Chem
, vol.272
, pp. 22583-22590
-
-
Beziat, F.1
Touraille, S.2
Debise, R.3
-
34
-
-
67650763249
-
Evaluation of a compartmental model for estimating tumor hypoxia via FMISO dynamic PET imaging
-
Wang W, Georgi JC, Nehmeh SA, et al. Evaluation of a compartmental model for estimating tumor hypoxia via FMISO dynamic PET imaging. Phys Med Biol 2009; 54: 3083-3099
-
(2009)
Phys Med Biol
, vol.54
, pp. 3083-3099
-
-
Wang, W.1
Georgi, J.C.2
Nehmeh, S.A.3
-
35
-
-
50449109986
-
11C-NMSP/ 18F-FDG microPET to monitor neural stem cell transplantation in a rat model of traumatic brain injury
-
Zhang H, Zheng X, Yang X, et al. 11C-NMSP/ 18F-FDG microPET to monitor neural stem cell transplantation in a rat model of traumatic brain injury. Eur J Nucl Med Mol Imaging 2008; 35: 1699-1708
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1699-1708
-
-
Zhang, H.1
Zheng, X.2
Yang, X.3
-
36
-
-
0019942798
-
Clinical experience with nitroimidazoles as radiosensitizers
-
Dische S, Saunders MI, Anderson P, Stratford MR, Minchinton A. Clinical experience with nitroimidazoles as radiosensitizers. Int J Radiat Oncol Biol Phys 1982; 8: 335-338
-
(1982)
Int J Radiat Oncol Biol Phys
, vol.8
, pp. 335-338
-
-
Dische, S.1
Saunders, M.I.2
Anderson, P.3
Stratford, M.R.4
Minchinton, A.5
-
38
-
-
0026009654
-
Reduction of fluoromisonidazole, a new imaging agent for hypoxia
-
Prekeges JL, Rasey JS, Grunbaum Z, Krohn KH. Reduction of fluoromisonidazole, a new imaging agent for hypoxia. Biochem Pharmacol 1991; 42: 2387-2395
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 2387-2395
-
-
Prekeges, J.L.1
Rasey, J.S.2
Grunbaum, Z.3
Krohn, K.H.4
-
39
-
-
15844368087
-
Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy
-
Eschmann SM, Paulsen F, Reimold M, et al. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med 2005; 46: 253-260
-
(2005)
J Nucl Med
, vol.46
, pp. 253-260
-
-
Eschmann, S.M.1
Paulsen, F.2
Reimold, M.3
-
41
-
-
0032768840
-
Comparison of the distribution of fluorine-18 fluoromisonidazole, deoxyglucose and methionine in tumour tissue
-
Kubota K, Tada M, Yamada S, et al. Comparison of the distribution of fluorine-18 fluoromisonidazole, deoxyglucose and methionine in tumour tissue. Eur J Nucl Med 1999; 26: 750-757
-
(1999)
Eur J Nucl Med
, vol.26
, pp. 750-757
-
-
Kubota, K.1
Tada, M.2
Yamada, S.3
-
43
-
-
33748185692
-
Imaging hypoxia after oxygenation-modification: Comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors
-
Troost EG, Laverman P, Kaanders JH, et al. Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors. Radiother Oncol 2006; 80: 157-164
-
(2006)
Radiother Oncol
, vol.80
, pp. 157-164
-
-
Troost, E.G.1
Laverman, P.2
Kaanders, J.H.3
-
44
-
-
11244287240
-
Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry
-
Dubois L, Landuyt W, Haustermans K, et al. Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry. Br J Cancer 2004; 91: 1947-1954.
-
(2004)
Br J Cancer
, vol.91
, pp. 1947-1954
-
-
Dubois, L.1
Landuyt, W.2
Haustermans, K.3
-
45
-
-
52449099235
-
Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts
-
Troost EG, Laverman P, Philippens ME, et al. Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts. Eur J Nucl Med Mol Imaging 2008; 35: 1803-1811
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1803-1811
-
-
Troost, E.G.1
Laverman, P.2
Philippens, M.E.3
-
46
-
-
69549138474
-
Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events
-
Lehmann S, Stiehl DP, Honer M, et al. Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proc Natl Acad Sci USA 2009; 106: 14004-14009
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14004-14009
-
-
Lehmann, S.1
Stiehl, D.P.2
Honer, M.3
-
47
-
-
0030249455
-
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: A pretherapy study of 37 patients
-
Rasey JS, Koh WJ, Evans ML, et al. Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients. Int J Radiat Oncol Biol Phys 1996; 36: 417-428
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.36
, pp. 417-428
-
-
Rasey, J.S.1
Koh, W.J.2
Evans, M.L.3
-
49
-
-
34547984111
-
pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: Validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?
-
Gagel B, Piroth M, Pinkawa M, et al. pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia? BMC Cancer 2007; 7: 113.
-
(2007)
BMC Cancer
, vol.7
, pp. 113
-
-
Gagel, B.1
Piroth, M.2
Pinkawa, M.3
-
50
-
-
24044503731
-
Assessing regional hypoxia in human renal tumours using 18F-fluoromisonidazole positron emission tomography
-
Lawrentschuk N, Poon AM, Foo SS, et al. Assessing regional hypoxia in human renal tumours using 18F-fluoromisonidazole positron emission tomography. BJU Int 2005; 96: 540-546
-
(2005)
BJU Int
, vol.96
, pp. 540-546
-
-
Lawrentschuk, N.1
Poon, A.M.2
Foo, S.S.3
-
51
-
-
0038642530
-
Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours
-
Bentzen L, Keiding S, Nordsmark M, et al. Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours. Radiother Oncol 2003; 67: 339-344
-
(2003)
Radiother Oncol
, vol.67
, pp. 339-344
-
-
Bentzen, L.1
Keiding, S.2
Nordsmark, M.3
-
52
-
-
33645969631
-
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies
-
Cher LM, Murone C, Lawrentschuk N, et al. Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies. J Nucl Med 2006; 47: 410-418
-
(2006)
J Nucl Med
, vol.47
, pp. 410-418
-
-
Cher, L.M.1
Murone, C.2
Lawrentschuk, N.3
-
53
-
-
34547883821
-
Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET
-
Cherk MH, Foo SS, Poon AM, et al. Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET. J Nucl Med 2006; 47: 1921-1926
-
(2006)
J Nucl Med
, vol.47
, pp. 1921-1926
-
-
Cherk, M.H.1
Foo, S.S.2
Poon, A.M.3
-
54
-
-
33748045490
-
Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients
-
Thorwarth D, Eschmann SM, Holzner F, Paulsen F, Alber M. Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients. Radiother Oncol 2006; 80: 151-156
-
(2006)
Radiother Oncol
, vol.80
, pp. 151-156
-
-
Thorwarth, D.1
Eschmann, S.M.2
Holzner, F.3
Paulsen, F.4
Alber, M.5
-
55
-
-
11144353536
-
Hypoxia and glucose metabolism in malignant tumors: Evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging
-
Rajendran JG, Mankoff DA, O'Sullivan F, et al. Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging. Clin Cancer Res 2004; 10: 2245-2252
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2245-2252
-
-
Rajendran, J.G.1
Mankoff, D.A.2
O'Sullivan, F.3
-
56
-
-
33749344131
-
Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer
-
Rajendran JG, Schwartz DL, O'Sullivan J, et al. Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer. Clin Cancer Res 2006; 12: 5435-5441
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5435-5441
-
-
Rajendran, J.G.1
Schwartz, D.L.2
O'Sullivan, J.3
-
57
-
-
28544444512
-
Utility of FMISO PET in advanced head and neck cancer treated with chemoradiation incorporating a hypoxia-targeting chemotherapy agent
-
Hicks RJ, Rischin D, Fisher R, Binns D, Scott AM, Peters LJ. Utility of FMISO PET in advanced head and neck cancer treated with chemoradiation incorporating a hypoxia-targeting chemotherapy agent. Eur J Nucl Med Mol Imaging 2005; 32: 1384-1391
-
(2005)
Eur J Nucl Med Mol Imaging
, vol.32
, pp. 1384-1391
-
-
Hicks, R.J.1
Rischin, D.2
Fisher, R.3
Binns, D.4
Scott, A.M.5
Peters, L.J.6
-
58
-
-
33646241326
-
[18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography in response evaluation after chemo-/radiotherapy of non-small-cell lung cancer: A feasibility study
-
Gagel B, Reinartz P, Demirel C, et al. [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography in response evaluation after chemo-/radiotherapy of non-small-cell lung cancer: a feasibility study. BMC Cancer 2006; 6: 51.
-
(2006)
BMC Cancer
, vol.6
, pp. 51
-
-
Gagel, B.1
Reinartz, P.2
Demirel, C.3
-
59
-
-
58149287834
-
Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage
-
Busk M, Horsman MR, Jakobsen S, Bussink J, van der Kogel A, Overgaard J. Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage. Eur J Nucl Med Mol Imaging 2008; 35: 2294-2303
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 2294-2303
-
-
Busk, M.1
Horsman, M.R.2
Jakobsen, S.3
Bussink, J.4
Van Der Kogel, A.5
Overgaard, J.6
-
60
-
-
15044349250
-
Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside
-
Piert M, Machulla HJ, Picchio M, et al. Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside. J Nucl Med 2005; 46: 106-113
-
(2005)
J Nucl Med
, vol.46
, pp. 106-113
-
-
Piert, M.1
Machulla, H.J.2
Picchio, M.3
-
62
-
-
34548485457
-
Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: A pilot study
-
Souvatzoglou M, Grosu AL, Roper B, et al. Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: a pilot study. Eur J Nucl Med Mol Imaging 2007; 34: 1566-1575
-
(2007)
Eur J Nucl Med Mol Imaging
, vol.34
, pp. 1566-1575
-
-
Souvatzoglou, M.1
Grosu, A.L.2
Roper, B.3
-
63
-
-
34249313652
-
Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA-first small animal PET results
-
Reischl G, Dorow DS, Cullinane C, et al. Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA-first small animal PET results. J Pharm Pharm Sci 2007; 10: 203-211
-
(2007)
J Pharm Pharm Sci
, vol.10
, pp. 203-211
-
-
Reischl, G.1
Dorow, D.S.2
Cullinane, C.3
-
64
-
-
34250326197
-
Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine
-
Beck R, Roper B, Carlsen JM, et al. Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine. J Nucl Med 2007; 48: 973-980
-
(2007)
J Nucl Med
, vol.48
, pp. 973-980
-
-
Beck, R.1
Roper, B.2
Carlsen, J.M.3
-
65
-
-
34548511596
-
Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer
-
Grosu AL, Souvatzoglou M, Roper B, et al. Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer. Int J Radiat Oncol Biol Phys 2007; 69: 541-551
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, pp. 541-551
-
-
Grosu, A.L.1
Souvatzoglou, M.2
Roper, B.3
-
66
-
-
70350532485
-
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]- fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA)
-
Postema EJ, McEwan AJ, Riauka TA, et al. Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2- nitroimidazole ( 18F-FAZA). Eur J Nucl Med Mol Imaging 2009; 36: 1565-1573
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 1565-1573
-
-
Postema, E.J.1
McEwan, A.J.2
Riauka, T.A.3
-
67
-
-
0026585518
-
Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: Preliminary report of a clinical study
-
Parliament MB, Chapman JD, Urtasun RC, et al. Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical study. Br J Cancer 1992; 65: 90-95
-
(1992)
Br J Cancer
, vol.65
, pp. 90-95
-
-
Parliament, M.B.1
Chapman, J.D.2
Urtasun, R.C.3
-
68
-
-
0025870484
-
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2- nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia
-
Mannan RH, Somayaji VV, Lee J, Mercer JR, Chapman JD, Wiebe LI. Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia. J Nucl Med 1991; 32:1764-1770
-
(1991)
J Nucl Med
, vol.32
, pp. 1764-1770
-
-
Mannan, R.H.1
Somayaji, V.V.2
Lee, J.3
Mercer, J.R.4
Chapman, J.D.5
Wiebe, L.I.6
-
69
-
-
0034741791
-
Dosimetry estimations for 123I-IAZA in healthy volunteers
-
Stypinski D, McQuarrie SA, Wiebe LI, Tam YK, Mercer JR, McEwan AJ. Dosimetry estimations for 123I-IAZA in healthy volunteers. J Nucl Med 2001; 42: 1418-1423
-
(2001)
J Nucl Med
, vol.42
, pp. 1418-1423
-
-
Stypinski, D.1
McQuarrie, S.A.2
Wiebe, L.I.3
Tam, Y.K.4
Mercer, J.R.5
McEwan, A.J.6
-
70
-
-
22144477893
-
[131I] Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: Radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice
-
Kumar P, McQuarrie SA, Zhou A, McEwan AJ, Wiebe LI. [131I] Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice. Nucl Med Biol 2005; 32: 647-653
-
(2005)
Nucl Med Biol
, vol.32
, pp. 647-653
-
-
Kumar, P.1
McQuarrie, S.A.2
Zhou, A.3
McEwan, A.J.4
Wiebe, L.I.5
-
71
-
-
0028917959
-
Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia
-
Yang DJ, Wallace S, Cherif A, et al. Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia. Radiology 1995; 194: 795-800.
-
(1995)
Radiology
, vol.194
, pp. 795-800
-
-
Yang, D.J.1
Wallace, S.2
Cherif, A.3
-
72
-
-
0036882163
-
18FFluoroerythronitroimidazole radiation dosimetry in cancer studies
-
Tolvanen T, Lehtio K, Kulmala J, et al. 18FFluoroerythronitroimidazole radiation dosimetry in cancer studies. J Nucl Med 2002; 43: 1674-1680
-
(2002)
J Nucl Med
, vol.43
, pp. 1674-1680
-
-
Tolvanen, T.1
Lehtio, K.2
Kulmala, J.3
-
73
-
-
0034843378
-
Pharmacokinetics of [18F]FETNIM: A potential marker for PET
-
Gronroos T, Eskola O, Lehtio K, et al. Pharmacokinetics of [18F]FETNIM: a potential marker for PET. J Nucl Med 2001; 42: 1397-1404
-
(2001)
J Nucl Med
, vol.42
, pp. 1397-1404
-
-
Gronroos, T.1
Eskola, O.2
Lehtio, K.3
-
74
-
-
11144357375
-
Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma
-
Gronroos T, Bentzen L, Marjamaki P, et al. Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma. Eur J Nucl Med Mol Imaging 2004; 31: 513-520
-
(2004)
Eur J Nucl Med Mol Imaging
, vol.31
, pp. 513-520
-
-
Gronroos, T.1
Bentzen, L.2
Marjamaki, P.3
-
75
-
-
0038207686
-
Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio
-
Lehtio K, Oikonen V, Nyman S, et al. Quantifying tumour hypoxia with fluorine-18 fluoroerythronitroimidazole ([18F]FETNIM) and PET using the tumour to plasma ratio. Eur J Nucl Med Mol Imaging 2003; 30: 101-108
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 101-108
-
-
Lehtio, K.1
Oikonen, V.2
Nyman, S.3
-
76
-
-
3042518844
-
Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-andneck cancer
-
Lehtio K, Eskola O, Viljanen T, et al. Imaging perfusion and hypoxia with PET to predict radiotherapy response in head-andneck cancer. Int J Radiat Oncol Biol Phys 2004; 59: 971-982
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.59
, pp. 971-982
-
-
Lehtio, K.1
Eskola, O.2
Viljanen, T.3
-
77
-
-
0030608674
-
Synthesis of [18F]fluoroetanidazole: A potential new tracer for imaging hypoxia
-
Tewson TJ. Synthesis of [18F]fluoroetanidazole: a potential new tracer for imaging hypoxia. Nucl Med Biol 1997; 24: 755-760
-
(1997)
Nucl Med Biol
, vol.24
, pp. 755-760
-
-
Tewson, T.J.1
-
78
-
-
0032587188
-
Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia
-
Rasey JS, Hofstrand PD, Chin LK, Tewson TJ. Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia. J Nucl Med 1999; 40: 1072-1079
-
(1999)
J Nucl Med
, vol.40
, pp. 1072-1079
-
-
Rasey, J.S.1
Hofstrand, P.D.2
Chin, L.K.3
Tewson, T.J.4
-
79
-
-
0028784382
-
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
-
Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer 1995; 72: 875-882
-
(1995)
Br J Cancer
, vol.72
, pp. 875-882
-
-
Evans, S.M.1
Joiner, B.2
Jenkins, W.T.3
Laughlin, K.M.4
Lord, E.M.5
Koch, C.J.6
-
80
-
-
52449098342
-
Measurements of hypoxia ([(18)F]-FMISO, [(18)F]-EF5) with positron emission tomography (PET) and perfusion using PET ([(15)O]-H(2)O) and power Doppler ultrasonography in feline fibrosarcomas*
-
Allemann K, Wyss MT, Wergin M, et al. Measurements of hypoxia ([(18)F]-FMISO, [(18)F]-EF5) with positron emission tomography (PET) and perfusion using PET ([(15)O]-H(2)O) and power Doppler ultrasonography in feline fibrosarcomas*. Vet Comp Oncol 2005; 3: 211-221
-
(2005)
Vet Comp Oncol
, vol.3
, pp. 211-221
-
-
Allemann, K.1
Wyss, M.T.2
Wergin, M.3
-
82
-
-
0033954168
-
Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1
-
Evans SM, Kachur AV, Shiue CY, et al. Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1. J Nucl Med 2000; 41: 327-336
-
(2000)
J Nucl Med
, vol.41
, pp. 327-336
-
-
Evans, S.M.1
Kachur, A.V.2
Shiue, C.Y.3
-
83
-
-
0034745413
-
Synthesis of [18F]-labeled EF3 [2-(2-nitroimidazol-1-yl)-N-(3,3,3- trifluoropropyl)-acetamide], a marker for PET detection of hypoxia
-
Josse O, Labar D, Georges B, Gregoire V, Marchand-Brynaert J. Synthesis of [18F]-labeled EF3 [2-(2-nitroimidazol-1-yl)-N-(3,3,3-trifluoropropyl)- acetamide], a marker for PET detection of hypoxia. Bioorg Med Chem 2001; 9: 665-675
-
(2001)
Bioorg Med Chem
, vol.9
, pp. 665-675
-
-
Josse, O.1
Labar, D.2
Georges, B.3
Gregoire, V.4
Marchand-Brynaert, J.5
-
84
-
-
4544242405
-
Preclinical validation of the hypoxia tracer 2-(2-nitroimidazol-1-yl)- N-(3,3,3-[(18)F]trifluoropropyl)acetamide, [(18)F]EF3
-
Mahy P, De Bast M, Leveque PH, et al. Preclinical validation of the hypoxia tracer 2-(2-nitroimidazol-1-yl)- N-(3,3,3-[(18)F]trifluoropropyl) acetamide, [(18)F]EF3. Eur J Nucl Med Mol Imaging 2004; 31: 1263-1272
-
(2004)
Eur J Nucl Med Mol Imaging
, vol.31
, pp. 1263-1272
-
-
Mahy, P.1
De Bast, M.2
Leveque, P.H.3
-
85
-
-
33646399189
-
Detection of tumour hypoxia: Comparison between EF5 adducts and [18F]EF3 uptake on an individual mouse tumour basis
-
Mahy P, De Bast M, Gillart J, Labar D, Gregoire V. Detection of tumour hypoxia: comparison between EF5 adducts and [18F]EF3 uptake on an individual mouse tumour basis. Eur J Nucl Med Mol Imaging 2006; 33: 553-556
-
(2006)
Eur J Nucl Med Mol Imaging
, vol.33
, pp. 553-556
-
-
Mahy, P.1
De Bast, M.2
Gillart, J.3
Labar, D.4
Gregoire, V.5
-
86
-
-
56849085305
-
Comparative pharmacokinetics, biodistribution, metabolism and hypoxiadependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models
-
Mahy P, De Bast M, de Groot T, et al. Comparative pharmacokinetics, biodistribution, metabolism and hypoxiadependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models. Radiother Oncol 2008; 89: 353-360
-
(2008)
Radiother Oncol
, vol.89
, pp. 353-360
-
-
Mahy, P.1
De Bast, M.2
De Groot, T.3
-
87
-
-
58849135714
-
[18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model
-
Dubois L, Landuyt W, Cloetens L, et al. [18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model. Eur J Nucl Med Mol Imaging 2009; 36: 209-218
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 209-218
-
-
Dubois, L.1
Landuyt, W.2
Cloetens, L.3
-
88
-
-
34548155736
-
Determination of tumour hypoxia with the PET tracer [18F]EF3: Improvement of the tumour-to-background ratio in a mouse tumour model
-
Christian N, Bol A, De Bast M, et al. Determination of tumour hypoxia with the PET tracer [18F]EF3: improvement of the tumour-to-background ratio in a mouse tumour model. Eur J Nucl Med Mol Imaging 2007; 34: 1348-1354
-
(2007)
Eur J Nucl Med Mol Imaging
, vol.34
, pp. 1348-1354
-
-
Christian, N.1
Bol, A.2
De Bast, M.3
-
89
-
-
0035503276
-
[18F]-EF5, a marker for PET detection of hypoxia: Synthesis of precursor and a new fluorination procedure
-
Dolbier WR, Jr., Li AR, Koch CJ, Shiue CY, Kachur AV. [18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure. Appl Radiat Isot 2001; 54: 73-80.
-
(2001)
Appl Radiat Isot
, vol.54
, pp. 73-80
-
-
Dolbier Jr., W.R.1
Li, A.R.2
Koch, C.J.3
Shiue, C.Y.4
Kachur, A.V.5
-
90
-
-
0038797936
-
Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5
-
Ziemer LS, Evans SM, Kachur AV, et al. Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5. Eur J Nucl Med Mol Imaging 2003; 30: 259-266
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 259-266
-
-
Ziemer, L.S.1
Evans, S.M.2
Kachur, A.V.3
-
91
-
-
34249951502
-
Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography
-
Yapp DT, Woo J, Kartono A, et al. Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography. BJU Int 2007; 99: 1154-1160
-
(2007)
BJU Int
, vol.99
, pp. 1154-1160
-
-
Yapp, D.T.1
Woo, J.2
Kartono, A.3
-
92
-
-
45049087914
-
Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: A phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism
-
Mahy P, Geets X, Lonneux M, et al. Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism. Eur J Nucl Med Mol Imaging 2008; 35: 1282-1289
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1282-1289
-
-
Mahy, P.1
Geets, X.2
Lonneux, M.3
-
93
-
-
57149111715
-
18F-EF5: A new PET tracer for imaging hypoxia in head and neck cancer
-
Komar G, Seppanen M, Eskola O, et al. 18F-EF5: a new PET tracer for imaging hypoxia in head and neck cancer. J Nucl Med 2008; 49: 1944-1951
-
(2008)
J Nucl Med
, vol.49
, pp. 1944-1951
-
-
Komar, G.1
Seppanen, M.2
Eskola, O.3
-
94
-
-
0030811565
-
Copper-62-ATSM: A new hypoxia imaging agent with high membrane permeability and low redox potential
-
Fujibayashi Y, Taniuchi H, Yonekura Y, Ohtani H, Konishi J, Yokoyama A. Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential. J Nucl Med 1997; 38: 1155-1160
-
(1997)
J Nucl Med
, vol.38
, pp. 1155-1160
-
-
Fujibayashi, Y.1
Taniuchi, H.2
Yonekura, Y.3
Ohtani, H.4
Konishi, J.5
Yokoyama, A.6
-
95
-
-
0035708693
-
Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cudiacetyl- Bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells
-
Obata A, Yoshimi E, Waki A, et al. Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cudiacetyl- bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells. Ann Nucl Med 2001; 15: 499-504.
-
(2001)
Ann Nucl Med
, vol.15
, pp. 499-504
-
-
Obata, A.1
Yoshimi, E.2
Waki, A.3
-
96
-
-
43049165789
-
[(64)Cu]diacetyl-bis(N(4)-methyl-thiosemicarbazone) - A radiotracer for tumor hypoxia
-
Wood KA, Wong WL, Saunders MI. [(64)Cu]diacetyl-bis(N(4)-methyl- thiosemicarbazone) - a radiotracer for tumor hypoxia. Nucl Med Biol 2008; 35: 393-400.
-
(2008)
Nucl Med Biol
, vol.35
, pp. 393-400
-
-
Wood, K.A.1
Wong, W.L.2
Saunders, M.I.3
-
97
-
-
69449094645
-
Assessing tumor hypoxia by positron emission tomography with Cu-ATSM
-
Holland JP, Lewis JS, Dehdashti F. Assessing tumor hypoxia by positron emission tomography with Cu-ATSM. Q J Nucl Med Mol Imaging. 2009; 53: 193-200.
-
(2009)
Q J Nucl Med Mol Imaging
, vol.53
, pp. 193-200
-
-
Holland, J.P.1
Lewis, J.S.2
Dehdashti, F.3
-
98
-
-
0031869326
-
Design of hypoxia-targeting radiopharmaceuticals: Selective uptake of copper-64 complexes in hypoxic cells in vitro
-
Dearling JL, Lewis JS, Mullen GE, Rae MT, Zweit J, Blower PJ. Design of hypoxia-targeting radiopharmaceuticals: selective uptake of copper-64 complexes in hypoxic cells in vitro. Eur J Nucl Med 1998; 25: 788-792
-
(1998)
Eur J Nucl Med
, vol.25
, pp. 788-792
-
-
Dearling, J.L.1
Lewis, J.S.2
Mullen, G.E.3
Rae, M.T.4
Zweit, J.5
Blower, P.J.6
-
99
-
-
0032587218
-
Evaluation of 64Cu-ATSM in vitro and in vivo in a hypoxic tumor model
-
Lewis JS, McCarthy DW, McCarthy TJ, Fujibayashi Y, Welch MJ. Evaluation of 64Cu-ATSM in vitro and in vivo in a hypoxic tumor model. J Nucl Med 1999; 40: 177-183
-
(1999)
J Nucl Med
, vol.40
, pp. 177-183
-
-
Lewis, J.S.1
McCarthy, D.W.2
McCarthy, T.J.3
Fujibayashi, Y.4
Welch, M.J.5
-
100
-
-
0035043960
-
Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): Effect of changes in tissue oxygenation
-
Lewis JS, Sharp TL, Laforest R, Fujibayashi Y, Welch MJ. Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation. J Nucl Med 2001; 42: 655-661
-
(2001)
J Nucl Med
, vol.42
, pp. 655-661
-
-
Lewis, J.S.1
Sharp, T.L.2
Laforest, R.3
Fujibayashi, Y.4
Welch, M.J.5
-
101
-
-
20144387807
-
2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models
-
2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. Int J Radiat Oncol Biol Phys 2005; 61: 1493-1502
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.61
, pp. 1493-1502
-
-
O'Donoghue, J.A.1
Zanzonico, P.2
Pugachev, A.3
-
102
-
-
33746089972
-
Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone)
-
Yuan H, Schroeder T, Bowsher JE, Hedlund LW, Wong T, Dewhirst MW. Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone). J Nucl Med 2006; 47: 989-998
-
(2006)
J Nucl Med
, vol.47
, pp. 989-998
-
-
Yuan, H.1
Schroeder, T.2
Bowsher, J.E.3
Hedlund, L.W.4
Wong, T.5
Dewhirst, M.W.6
-
103
-
-
33747341325
-
Double-tracer autoradiography with Cu-ATSM/FDG and immunohistochemical interpretation in four different mouse implanted tumor models
-
Tanaka T, Furukawa T, Fujieda S, Kasamatsu S, Yonekura Y, Fujibayashi Y. Double-tracer autoradiography with Cu-ATSM/FDG and immunohistochemical interpretation in four different mouse implanted tumor models. Nucl Med Biol 2006; 33: 743-750
-
(2006)
Nucl Med Biol
, vol.33
, pp. 743-750
-
-
Tanaka, T.1
Furukawa, T.2
Fujieda, S.3
Kasamatsu, S.4
Yonekura, Y.5
Fujibayashi, Y.6
-
104
-
-
67349100641
-
Radio-copper-labeled Cu- ATSM: An indicator of quiescent but clonogenic cells under mild hypoxia in a Lewis lung carcinoma model
-
Oh M, Tanaka T, Kobayashi M, et al. Radio-copper-labeled Cu- ATSM: an indicator of quiescent but clonogenic cells under mild hypoxia in a Lewis lung carcinoma model. Nucl Med Biol 2009; 36: 419-426
-
(2009)
Nucl Med Biol
, vol.36
, pp. 419-426
-
-
Oh, M.1
Tanaka, T.2
Kobayashi, M.3
-
105
-
-
0035970009
-
Copper-64-diacetyl-bis(N4- Methylthiosemicarbazone): An agent for radiotherapy
-
Lewis J, Laforest R, Buettner T, et al. Copper-64-diacetyl-bis(N4- methylthiosemicarbazone): An agent for radiotherapy. Proc Natl Acad Sci USA 2001; 98: 1206-1211
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1206-1211
-
-
Lewis, J.1
Laforest, R.2
Buettner, T.3
-
106
-
-
77950270408
-
Radiobiological effects of hypoxia-dependent uptake of (64)Cu-ATSM: Enhanced DNA damage and cytotoxicity in hypoxic cells
-
Epub ahead of print
-
Weeks AJ, Paul RL, Marsden PK, Blower PJ, Lloyd DR. Radiobiological effects of hypoxia-dependent uptake of (64)Cu-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells. Eur J Nucl Med Mol Imaging 2009. Epub ahead of print.
-
(2009)
Eur J Nucl Med Mol Imaging
-
-
Weeks, A.J.1
Paul, R.L.2
Marsden, P.K.3
Blower, P.J.4
Lloyd, D.R.5
-
107
-
-
0242417596
-
Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM: Relationship to therapeutic response-a preliminary report
-
Dehdashti F, Grigsby PW, Mintun MA, Lewis JS, Siegel BA, Welch MJ. Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM: relationship to therapeutic response-a preliminary report. Int J Radiat Oncol Biol Phys 2003; 55: 1233-1238
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.55
, pp. 1233-1238
-
-
Dehdashti, F.1
Grigsby, P.W.2
Mintun, M.A.3
Lewis, J.S.4
Siegel, B.A.5
Welch, M.J.6
-
108
-
-
0038376175
-
In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM
-
Dehdashti F, Mintun MA, Lewis JS, et al. In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM. Eur J Nucl Med Mol Imaging 2003; 30: 844-850
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 844-850
-
-
Dehdashti, F.1
Mintun, M.A.2
Lewis, J.S.3
-
109
-
-
54949157918
-
Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing Neoadjuvant chemoradiotherapy for rectal carcinoma: A pilot study
-
Dietz DW, Dehdashti F, Grigsby PW, et al. Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing Neoadjuvant chemoradiotherapy for rectal carcinoma: a pilot study. Dis Colon Rectum 2008; 51: 1641-1648
-
(2008)
Dis Colon Rectum
, vol.51
, pp. 1641-1648
-
-
Dietz, D.W.1
Dehdashti, F.2
Grigsby, P.W.3
-
110
-
-
46749093400
-
An imaging comparison of 64Cu-ATSM and 60Cu-ATSM in cancer of the uterine cervix
-
Lewis JS, Laforest R, Dehdashti F, Grigsby PW, Welch MJ, Siegel BA. An imaging comparison of 64Cu-ATSM and 60Cu-ATSM in cancer of the uterine cervix. J Nucl Med 2008; 49: 1177-1182
-
(2008)
J Nucl Med
, vol.49
, pp. 1177-1182
-
-
Lewis, J.S.1
Laforest, R.2
Dehdashti, F.3
Grigsby, P.W.4
Welch, M.J.5
Siegel, B.A.6
-
111
-
-
38949098088
-
Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone)
-
Dehdashti F, Grigsby PW, Lewis JS, Laforest R, Siegel BA, Welch MJ. Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone). J Nucl Med 2008; 49: 201-205
-
(2008)
J Nucl Med
, vol.49
, pp. 201-205
-
-
Dehdashti, F.1
Grigsby, P.W.2
Lewis, J.S.3
Laforest, R.4
Siegel, B.A.5
Welch, M.J.6
-
112
-
-
34548151815
-
Comparison of molecular markers of hypoxia and imaging with (60)Cu-ATSM in cancer of the uterine cervix
-
Grigsby PW, Malyapa RS, Higashikubo R, et al. Comparison of molecular markers of hypoxia and imaging with (60)Cu-ATSM in cancer of the uterine cervix. Mol Imaging Biol 2007; 9: 278-283
-
(2007)
Mol Imaging Biol
, vol.9
, pp. 278-283
-
-
Grigsby, P.W.1
Malyapa, R.S.2
Higashikubo, R.3
-
113
-
-
0035869722
-
A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
-
Chao KS, Bosch WR, Mutic S, et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2001; 49: 1171-1182
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 1171-1182
-
-
Chao, K.S.1
Bosch, W.R.2
Mutic, S.3
-
114
-
-
63649148095
-
On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function
-
Bowen SR, Flynn RT, Bentzen SM, Jeraj R. On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function. Phys Med Biol 2009; 54: 1483-1501
-
(2009)
Phys Med Biol
, vol.54
, pp. 1483-1501
-
-
Bowen, S.R.1
Flynn, R.T.2
Bentzen, S.M.3
Jeraj, R.4
-
115
-
-
48349130527
-
Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting
-
Flynn RT, Bowen SR, Bentzen SM, Rockwell Mackie T, Jeraj R. Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting. Phys Med Biol 2008; 53: 4153-4167
-
(2008)
Phys Med Biol
, vol.53
, pp. 4153-4167
-
-
Flynn, R.T.1
Bowen, S.R.2
Bentzen, S.M.3
Rockwell Mackie, T.4
Jeraj, R.5
|