-
1
-
-
0033405294
-
The hypoxic cell: A target for selective cancer therapy - Eighteenth Bruce F. Cain Memorial Award lecture
-
Brown JM. The hypoxic cell: a target for selective cancer therapy - eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res 1999;59:5863-70.
-
(1999)
Cancer Res
, vol.59
, pp. 5863-5870
-
-
Brown, J.M.1
-
2
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998;58:1408-16.
-
(1998)
Cancer Res
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
3
-
-
0027339592
-
2 predicts survival in advanced cancer of the uterine cervix
-
Höckel M, Knoop C, Schlenger K, Vorndran B, Baussmann E, Mitze M et al. Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol 1993;26:45-50. (Pubitemid 23063609)
-
(1993)
Radiotherapy and Oncology
, vol.26
, Issue.1
, pp. 45-50
-
-
Hockel, M.1
Knoop, C.2
Schlenger, K.3
Vorndran, B.4
Baussmann, E.5
Mitze, M.6
Knapstein, P.G.7
Vaupel, P.8
-
4
-
-
0028183119
-
2 histography as predictive assay in advanced cancer of the uterine cervix
-
Höckel M, Knoop C, Schlenger K, Vorndran B, Knapstein PG, Vaupel P. Intratumoral pO2 histography as predictive assay in advanced cancer of the uterine cervix. Adv Exp Med Biol 1994;345:445-50. (Pubitemid 24145783)
-
(1994)
Advances in Experimental Medicine and Biology
, vol.345
, pp. 445-450
-
-
Hockel, M.1
Knoop, C.2
Schlenger, K.3
Vorndran, B.4
Knapstein, P.G.5
Vaupel, P.6
-
5
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Höckel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-15. (Pubitemid 26330463)
-
(1996)
Cancer Research
, vol.56
, Issue.19
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaffer, U.5
Vaupel, P.6
-
6
-
-
0342857011
-
Tumor hypoxia in pelvic recurrences of cervical cancer
-
Höckel M, Schlenger K, Höckel S, Aral B, Schaffer U, Vaupel P. Tumor hypoxia in pelvic recurrences of cervical cancer. Int J Cancer 1998;79:365-9.
-
(1998)
Int J Cancer
, vol.79
, pp. 365-369
-
-
Höckel, M.1
Schlenger, K.2
Höckel, S.3
Aral, B.4
Schaffer, U.5
Vaupel, P.6
-
7
-
-
0026356726
-
Oxygenation of carcinomas of the uterine cervix: Evaluation by computerized O2 tension measurements
-
Höckel M, Schlenger K, Knoop C, Vaupel P. Oxygenation of carcinomas of the uterine cervix: evaluation by computerized O2 tension measurements. Cancer Res 1991;51:6098-102.
-
(1991)
Cancer Res
, vol.51
, pp. 6098-6102
-
-
Höckel, M.1
Schlenger, K.2
Knoop, C.3
Vaupel, P.4
-
8
-
-
0033922706
-
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
-
Rofstad EK, Sundfor K, Lyng H, Trope CG. Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br J Cancer 2000;83:354-9.
-
(2000)
Br J Cancer
, vol.83
, pp. 354-359
-
-
Rofstad, E.K.1
Sundfor, K.2
Lyng, H.3
Trope, C.G.4
-
9
-
-
0035501217
-
Tumor size and oxygenation are independent predictors of nodal diseases in patients with cervix cancer
-
Pitson G, Fyles A, Milosevic M, Wylie J, Pintilie M, Hill R. Tumor size and oxygenation are independent predictors of nodal diseases in patients with cervix cancer. Int J Radiat Oncol Biol Phys 2001;51:699-703.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 699-703
-
-
Pitson, G.1
Fyles, A.2
Milosevic, M.3
Wylie, J.4
Pintilie, M.5
Hill, R.6
-
10
-
-
33750108975
-
Hypoxia in head and neck cancer
-
Isa AY, Ward TH, West CM, Slevin NJ, Homer JJ. Hypoxia in head and neck cancer. Br J Radiol 2006;79:791-8.
-
(2006)
Br J Radiol
, vol.79
, pp. 791-798
-
-
Isa, A.Y.1
Ward, T.H.2
West, C.M.3
Slevin, N.J.4
Homer, J.J.5
-
11
-
-
0030292909
-
Copper radionuclides and radiopharmaceuticals in nuclear medicine
-
Blower PJ, Lewis JS, Zweit J. Copper radionuclides and radiopharmaceuticals in nuclear medicine. Nucl Med Biol 1996;23:957-80.
-
(1996)
Nucl Med Biol
, vol.23
, pp. 957-980
-
-
Blower, P.J.1
Lewis, J.S.2
Zweit, J.3
-
12
-
-
3142752475
-
Chemistry of copper radionuclides and radiopharmaceutical products
-
Welch WJ, Redvanly C, editors. West. Sussex, England: John Wiley & Sons, Ltd.
-
Anderson CJ, Green MA, Fujibayashi Y. Chemistry of copper radionuclides and radiopharmaceutical products. In: Welch WJ, Redvanly C, editors. Handbook of Radiopharmaceuticals: radiochemistry and applications. West. Sussex, England: John Wiley & Sons, Ltd.; 2003.p.401-22.
-
(2003)
Handbook of Radiopharmaceuticals: Radiochemistry and Applications
, pp. 401-422
-
-
Anderson, C.J.1
Green, M.A.2
Fujibayashi, Y.3
-
13
-
-
0001579481
-
Radiometal-labeled agents (non-technetium) for diagnostic imaging
-
Anderson CJ, Welch MJ. Radiometal-labeled agents (non-technetium) for diagnostic imaging. Chem Rev 1999;99:2219-34.
-
(1999)
Chem Rev
, vol.99
, pp. 2219-2234
-
-
Anderson, C.J.1
Welch, M.J.2
-
14
-
-
0036596118
-
Copper-67 as a therapeutic nuclide for radioimmunotherapy
-
Novak-Hofer I, Schubiger PA. Copper-67 as a therapeutic nuclide for radioimmunotherapy. Eur J Nucl Med Mol Imaging 2002;29:821-30.
-
(2002)
Eur J Nucl Med Mol Imaging
, vol.29
, pp. 821-830
-
-
Novak-Hofer, I.1
Schubiger, P.A.2
-
15
-
-
7644219830
-
Molecular imaging with copper-64
-
Smith SV. Molecular imaging with copper-64. J Inorg Biochem 2004;98:1874-901.
-
(2004)
J Inorg Biochem
, vol.98
, pp. 1874-1901
-
-
Smith, S.V.1
-
17
-
-
35548962244
-
Cu-ATSM: A radiopharmaceutical for the PET imaging of hypoxia
-
V□vere AL, Lewis JS. Cu-ATSM: a radiopharmaceutical for the PET imaging of hypoxia. Dalton Trans 2007;:4893-902.
-
(2007)
Dalton Trans
, pp. 4893-4902
-
-
Vvere, A.L.1
Lewis, J.S.2
-
18
-
-
84906319656
-
Metal radionuclides for PET imaging
-
Valk PE, Bailey DL, Townsend DW, Maisey MN, editors. London: Springer-Verlag London Ltd.
-
McQuade P, McCarthy DW, Welch MJ. Metal radionuclides for PET imaging. In: Valk PE, Bailey DL, Townsend DW, Maisey MN, editors. Positron emission tomography: basic science and clinical practice. London: Springer-Verlag London Ltd.; 2003.p.237-64.
-
(2003)
Positron Emission Tomography: Basic Science and Clinical Practice
, pp. 237-264
-
-
McQuade, P.1
McCarthy, D.W.2
Welch, M.J.3
-
19
-
-
0033051282
-
High purity production and potential applications of copper-60 and copper-61
-
McCarthy DW, Bass LA, Cutler PD, Shefer RE, Klinkowstein RE, Herrero P et al. High purity production and potential applications of copper-60 and copper-61. Nucl Med Biol 1999;26:351-8.
-
(1999)
Nucl Med Biol
, vol.26
, pp. 351-358
-
-
McCarthy, D.W.1
Bass, L.A.2
Cutler, P.D.3
Shefer, R.E.4
Klinkowstein, R.E.5
Herrero, P.6
-
21
-
-
0038433307
-
Production of therapeutic quantities of (64)Cu using a 12 MeV cyclotron
-
Obata A, Kasamatsu S, McCarthy DW, Welch MJ, Saji H, Yonekura Y et al. Production of therapeutic quantities of (64)Cu using a 12 MeV cyclotron. Nucl Med Biol 2003;30:535-9.
-
(2003)
Nucl Med Biol
, vol.30
, pp. 535-539
-
-
Obata, A.1
Kasamatsu, S.2
McCarthy, D.W.3
Welch, M.J.4
Saji, H.5
Yonekura, Y.6
-
24
-
-
0026778983
-
Copper-64-labeled antibodies for PET imaging
-
Anderson CJ, Connett JM, Schwarz SW, Rocque PA, Guo LW, Philpott GW et al. Copper-64-labeled antibodies for PET imaging. J Nucl Med 1992;33:1685-91.
-
(1992)
J Nucl Med
, vol.33
, pp. 1685-1691
-
-
Anderson, C.J.1
Connett, J.M.2
Schwarz, S.W.3
Rocque, P.A.4
Guo, L.W.5
Philpott, G.W.6
-
25
-
-
0035667652
-
64Cu-BAT-2IT-1A3
-
64Cu-BAT-2IT- 1A3. Cancer Biother Radiopharm 2001;16:483-94. (Pubitemid 34024436)
-
(2001)
Cancer Biotherapy and Radiopharmaceuticals
, vol.16
, Issue.6
, pp. 483-494
-
-
Lewis, M.R.1
Boswell, C.A.2
Laforest, R.3
Buettner, T.L.4
Ye, D.5
Connett, J.M.6
Anderson, C.J.7
-
26
-
-
0030811565
-
Copper-62-ATSM: A new hypoxia imaging agent with high membrane permeability and low redox potential
-
Fujibayashi Y, Taniuchi H, Yonekura Y, Ohtani H, Konishi J, Yokoyama A. Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential. J Nucl Med 1997;38:1155-60. (Pubitemid 27339632)
-
(1997)
Journal of Nuclear Medicine
, vol.38
, Issue.7
, pp. 1155-1160
-
-
Fujibayashi, Y.1
Taniuchi, H.2
Yonekura, Y.3
Ohtani, H.4
Konishi, J.5
Yokoyama, A.6
-
27
-
-
0032556442
-
Redox-active metal complexes for imaging hypoxic tissues: Structure-activity relationships in cooper(II)bis(thiosemicarbazone) complexes
-
Camb
-
Dearling JLJ, Lewis JS, McCarthy DW, Welch MJ, Blower PJ. Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in cooper(II)bis(thiosemicarbazone) complexes. Chem Commun (Camb) 1998;22:2531-2.
-
(1998)
Chem Commun
, vol.22
, pp. 2531-2532
-
-
Dearling, J.L.J.1
Lewis, J.S.2
McCarthy, D.W.3
Welch, M.J.4
Blower, P.J.5
-
28
-
-
0036943656
-
Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: Structure-activity relationships
-
Dearling JL, Lewis JS, Mullen GE, Welch MJ, Blower PJ. Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships. J Biol Inorg Chem 2002;7:249-59.
-
(2002)
J Biol Inorg Chem
, vol.7
, pp. 249-259
-
-
Dearling, J.L.1
Lewis, J.S.2
Mullen, G.E.3
Welch, M.J.4
Blower, P.J.5
-
30
-
-
22144449210
-
Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM
-
Burgman P, O'Donoghue JA, Lewis JS, Welch MJ, Humm JL, Ling CC. Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM. Nucl Med Biol 2005;32:623-30.
-
(2005)
Nucl Med Biol
, vol.32
, pp. 623-630
-
-
Burgman, P.1
O'Donoghue, J.A.2
Lewis, J.S.3
Welch, M.J.4
Humm, J.L.5
Ling, C.C.6
-
31
-
-
0035043960
-
4- methylthiosemicarbazone): Effect of changes in tissue oxygenation
-
Lewis JS, Sharp TL, Laforest R, Fujibayashi Y, Welch MJ. Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation. J Nucl Med 2001;42:655-61. (Pubitemid 32298288)
-
(2001)
Journal of Nuclear Medicine
, vol.42
, Issue.4
, pp. 655-661
-
-
Lewis, J.S.1
Sharp, T.L.2
Laforest, R.3
Fujibayashi, Y.4
Welch, M.J.5
-
34
-
-
33746474625
-
Hypoxia imaging-directed radiation treatment planning
-
Rajendran JG, Hendrickson KR, Spence AM, Muzi M, Krohn KA, Mankoff DA. Hypoxia imaging-directed radiation treatment planning. Eur J Nucl Med Mol Imaging 2006;33 Suppl 1:44-53.
-
(2006)
Eur J Nucl Med Mol Imaging
, vol.33
, Issue.SUPPL. 1
, pp. 44-53
-
-
Rajendran, J.G.1
Hendrickson, K.R.2
Spence, A.M.3
Muzi, M.4
Krohn, K.A.5
Mankoff, D.A.6
-
35
-
-
12444290525
-
[(18)F]FMISO and [(18)F]FDG PET imaging in soft tissue sarcomas: Correlation of hypoxia, metabolism and VEGF expression
-
Rajendran JG, Wilson DC, Conrad EU, Peterson LM, Bruckner JD, Rasey JS et al. [(18)F]FMISO and [(18)F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression. Eur J Nucl Med Mol Imaging 2003;30:695-704.
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 695-704
-
-
Rajendran, J.G.1
Wilson, D.C.2
Conrad, E.U.3
Peterson, L.M.4
Bruckner, J.D.5
Rasey, J.S.6
-
36
-
-
0035708693
-
4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells
-
Obata A, Yoshimi E, Waki A, Lewis JS, Oyama N, Welch MJ et al. Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells. Ann Nucl Med 2001;15:499-504. (Pubitemid 34131947)
-
(2001)
Annals of Nuclear Medicine
, vol.15
, Issue.6
, pp. 499-504
-
-
Obata, A.1
Yoshimi, E.2
Waki, A.3
Lewis, J.S.4
Oyama, N.5
Welch, M.J.6
Saji, H.7
Yonekura, Y.8
Fujibayashi, Y.9
-
37
-
-
0037187390
-
Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals
-
Maurer RI, Blower PJ, Dilworth JR, Reynolds CA, Zheng Y, Mullen GE. Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals. J Med Chem 2002;45:1420-31.
-
(2002)
J Med Chem
, vol.45
, pp. 1420-1431
-
-
Maurer, R.I.1
Blower, P.J.2
Dilworth, J.R.3
Reynolds, C.A.4
Zheng, Y.5
Mullen, G.E.6
-
38
-
-
33645500840
-
Probing the mechanism of hypoxia selectivity of copper bis(thiosemicarbazonato) complexes: DFT calculation of redox potentials and absolute acidities in solution
-
Holland JP, Green JC, Dilworth JR. Probing the mechanism of hypoxia selectivity of copper bis(thiosemicarbazonato) complexes: DFT calculation of redox potentials and absolute acidities in solution. Dalton Trans 2006;:783-94.
-
(2006)
Dalton Trans
, pp. 783-794
-
-
Holland, J.P.1
Green, J.C.2
Dilworth, J.R.3
-
39
-
-
53849090250
-
Spectroelectrochemical and computational studies on the mechanism of hypoxia selectivity of copper radiopharmaceuticals
-
Holland JP, Barnard PJ, Collison D, Dilworth JR, Edge R, Green JC et al. Spectroelectrochemical and computational studies on the mechanism of hypoxia selectivity of copper radiopharmaceuticals. Chemistry 2008;14:5890-907.
-
(2008)
Chemistry
, vol.14
, pp. 5890-5907
-
-
Holland, J.P.1
Barnard, P.J.2
Collison, D.3
Dilworth, J.R.4
Edge, R.5
Green, J.C.6
-
40
-
-
0028150810
-
Clinical application and quantitative evaluation of generator-produced copper-62-PTSM as a brain perfusion tracer for PET
-
Okazawa H, Yonekura Y, Fujibayashi Y, Nishizawa S, Magata Y, Ishizu K et al. Clinical application and quantitative evaluation of generator-produced copper-62-PTSM as a brain perfusion tracer for PET. J Nucl Med 1994;35:1910-5. (Pubitemid 24376602)
-
(1994)
Journal of Nuclear Medicine
, vol.35
, Issue.12
, pp. 1910-1915
-
-
Okazawa, H.1
Yonekura, Y.2
Fujibayashi, Y.3
Nishizawa, S.4
Magata, Y.5
Ishizu, K.6
Tanaka, F.7
Tsuchida, T.8
Tamaki, N.9
Konishi, J.10
-
42
-
-
0035869722
-
A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
-
Chao KS, Bosch WR, Mutic S, Lewis JS, Dehdashti F, Mintun MA et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2001;49:1171-82.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 1171-1182
-
-
Chao, K.S.1
Bosch, W.R.2
Mutic, S.3
Lewis, J.S.4
Dehdashti, F.5
Mintun, M.A.6
-
47
-
-
33751543273
-
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
-
Tatum JL, Kelloff GJ, Gillies RJ, Arbeit JM, Brown JM, Chao KS et al. Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol 2006;82:699-757.
-
(2006)
Int J Radiat Biol
, vol.82
, pp. 699-757
-
-
Tatum, J.L.1
Kelloff, G.J.2
Gillies, R.J.3
Arbeit, J.M.4
Brown, J.M.5
Chao, K.S.6
-
48
-
-
33846591866
-
Functionalized bis(thiosemicarbazonato) complexes of zinc and copper: Synthetic platforms toward site-specific radiopharmaceuticals
-
Holland JP, Aigbirhio FI, Betts HM, Bonnitcha PD, Burke P, Christlieb M et al. Functionalized bis(thiosemicarbazonato) complexes of zinc and copper: synthetic platforms toward site-specific radiopharmaceuticals. Inorg Chem 2007;46:465-85.
-
(2007)
Inorg Chem
, vol.46
, pp. 465-485
-
-
Holland, J.P.1
Aigbirhio, F.I.2
Betts, H.M.3
Bonnitcha, P.D.4
Burke, P.5
Christlieb, M.6
-
50
-
-
53349162465
-
Synthesis, radiolabeling and confocal fluorescence microscopy of styrene-derivatised bis(thiosemicarbazonato)zinc and -copper complexes
-
Holland JP, Barnard PJ, Bayly SR, Betts HM, Churchill GC, Dilworth JR et al. Synthesis, radiolabeling and confocal fluorescence microscopy of styrene-derivatised bis(thiosemicarbazonato)zinc and -copper complexes. Eur J Inorg Chem 2008;12:1985-93.
-
(2008)
Eur J Inorg Chem
, vol.12
, pp. 1985-1993
-
-
Holland, J.P.1
Barnard, P.J.2
Bayly, S.R.3
Betts, H.M.4
Churchill, G.C.5
Dilworth, J.R.6
-
52
-
-
54249100377
-
Controlled axial coordination: Solid-phase synthesis and purification of metallo-radiopharmaceuticals
-
Betts HM, Barnard PJ, Bayly SR, Dilworth JR, Gee AD, Holland JP. Controlled axial coordination: solid-phase synthesis and purification of metallo-radiopharmaceuticals. Angew Chem Int Ed Engl 2008;47:8416-9.
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, pp. 8416-8419
-
-
Betts, H.M.1
Barnard, P.J.2
Bayly, S.R.3
Dilworth, J.R.4
Gee, A.D.5
Holland, J.P.6
|