-
1
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 1996;56:4509-4515.
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schaffer, U.5
Vaupel, P.6
-
2
-
-
0030742027
-
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
-
Brizel DM, Sibley GS, Prosnitz LR, Scher RL, Dewhirst MW. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 1997;38:285-289.
-
(1997)
Int J Radiat Oncol Biol Phys
, vol.38
, pp. 285-289
-
-
Brizel, D.M.1
Sibley, G.S.2
Prosnitz, L.R.3
Scher, R.L.4
Dewhirst, M.W.5
-
3
-
-
0029753768
-
Genetic instability induced by the tumor microenvironment
-
Reynolds TY, Rockwell S, Glazer PM. Genetic instability induced by the tumor microenvironment. Cancer Res. 1996;56:5754-5757.
-
(1996)
Cancer Res
, vol.56
, pp. 5754-5757
-
-
Reynolds, T.Y.1
Rockwell, S.2
Glazer, P.M.3
-
4
-
-
0028864565
-
Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker
-
Waleh N, Brody M, Knapp M, et al. Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. Cancer Res. 1995;55:6222-6226.
-
(1995)
Cancer Res
, vol.55
, pp. 6222-6226
-
-
Waleh, N.1
Brody, M.2
Knapp, M.3
-
5
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
Brizel DM, Scully SP, Harrelson JM, et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res. 1996;56:941-943.
-
(1996)
Cancer Res
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
6
-
-
0027534567
-
Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers
-
Olive PL, Durand RE, LeRiche J, Jackson SM. Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers. Cancer Res. 1993;53:733-736.
-
(1993)
Cancer Res
, vol.53
, pp. 733-736
-
-
Olive, P.L.1
Durand, R.E.2
LeRiche, J.3
Jackson, S.M.4
-
7
-
-
0030032543
-
2-nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. Tumors
-
Evans SM, Jenkins WT, Joiner B, Lord EM, Koch CJ. 2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors. Cancer Res. 1996;56:405-411.
-
(1996)
Cancer Res
, vol.56
, pp. 405-411
-
-
Evans, S.M.1
Jenkins, W.T.2
Joiner, B.3
Lord, E.M.4
Koch, C.J.5
-
8
-
-
0028839715
-
Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide]: Analysis of drug adducts by fluorescent antibodies vs bound radioactivity
-
Koch CJ, Evans SM, Lord EM. Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide]: analysis of drug adducts by fluorescent antibodies vs bound radioactivity. Br J Cancer. 1995;72:869-874.
-
(1995)
Br J Cancer
, vol.72
, pp. 869-874
-
-
Koch, C.J.1
Evans, S.M.2
Lord, E.M.3
-
9
-
-
0026022735
-
Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection
-
Hodgkiss RJ, Jones G, Long A, et al. Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection. Br J Cancer. 1991;63: 119-125.
-
(1991)
Br J Cancer
, vol.63
, pp. 119-125
-
-
Hodgkiss, R.J.1
Jones, G.2
Long, A.3
-
10
-
-
0023633829
-
Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours
-
Raleigh JA, Miller GG, Franko AJ, Koch CJ, Fuciarelli AF, Kelley DA. Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. Br J Cancer. 1987;56:395-400.
-
(1987)
Br J Cancer
, vol.56
, pp. 395-400
-
-
Raleigh, J.A.1
Miller, G.G.2
Franko, A.J.3
Koch, C.J.4
Fuciarelli, A.F.5
Kelley, D.A.6
-
11
-
-
0023638854
-
Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells
-
Rasey JS, Grunbaum Z, Magee S, et al. Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells. Radiat Res. 1987;111:292-304.
-
(1987)
Radiat Res
, vol.111
, pp. 292-304
-
-
Rasey, J.S.1
Grunbaum, Z.2
Magee, S.3
-
12
-
-
0017089008
-
Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by chinese hamster ovary cells and KHT tumor cells in vitro and in vivo
-
Varghese AJ, Gulyas S, Mohindra JK. Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo. Cancer Res. 1976;36:3761-3765.
-
(1976)
Cancer Res.
, vol.36
, pp. 3761-3765
-
-
Varghese, A.J.1
Gulyas, S.2
Mohindra, J.K.3
-
13
-
-
0028784382
-
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
-
Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer. 1995;72:875-882.
-
(1995)
Br J Cancer
, vol.72
, pp. 875-882
-
-
Evans, S.M.1
Joiner, B.2
Jenkins, W.T.3
Laughlin, K.M.4
Lord, E.M.5
Koch, C.J.6
-
14
-
-
0031981258
-
Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays
-
Chapman JD, Engelhardt EL, Stobbe CC, Schneider RF, Hanks GE. Measuring hypoxia and predicting tumor radioresistance with nuclear medicine assays. Radiother Oncol. 1998;46:229-237.
-
(1998)
Radiother Oncol
, vol.46
, pp. 229-237
-
-
Chapman, J.D.1
Engelhardt, E.L.2
Stobbe, C.C.3
Schneider, R.F.4
Hanks, G.E.5
-
15
-
-
0028167554
-
TcO(PnA-O-1-(2-nitroimidaxzole)) [BMS-181321] a new technetium-containing nitroimidazole complex for imaging hypoxia: Synthesis, characterization, and xanthine oxidase catalyzed reduction
-
Linder K, Chan Y, Cyr J, Malley M, Nowotnik D, Nunn A. TcO(PnA-O-1-(2-nitroimidaxzole)) [BMS-181321] a new technetium-containing nitroimidazole complex for imaging hypoxia: synthesis, characterization, and xanthine oxidase catalyzed reduction. J Med Chem. 1994;37:9-17.
-
(1994)
J Med Chem
, vol.37
, pp. 9-17
-
-
Linder, K.1
Chan, Y.2
Cyr, J.3
Malley, M.4
Nowotnik, D.5
Nunn, A.6
-
16
-
-
0027376264
-
Detection of hypoxic cells by monoclonal antibody-recognizing 2-nitroimidazole adducts
-
Lord EM, Harwell L, Koch CJ. Detection of hypoxic cells by monoclonal antibody-recognizing 2-nitroimidazole adducts. Cancer Res. 1993;53:5271-5276.
-
(1993)
Cancer Res
, vol.53
, pp. 5271-5276
-
-
Lord, E.M.1
Harwell, L.2
Koch, C.J.3
-
17
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 1998;58:1408-1416.
-
(1998)
Cancer Res
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
19
-
-
0030980637
-
Three-dimensional imaging characteristics of the HEAD PENN-PET scanner
-
Karp JS, Freifelder R, Geagan MJ, et al. Three-dimensional imaging characteristics of the HEAD PENN-PET scanner. J Nucl Med. 1997;38:636-643.
-
(1997)
J Nucl Med
, vol.38
, pp. 636-643
-
-
Karp, J.S.1
Freifelder, R.2
Geagan, M.J.3
-
20
-
-
0025630135
-
Immunohistochemical detection of a hypoxia marker in spontaneous canine tumours
-
Cline JM, Thrall DE, Page RL, Franko AJ, Raleigh JA. Immunohistochemical detection of a hypoxia marker in spontaneous canine tumours. Br J Cancer. 1990;62:925-931.
-
(1990)
Br J Cancer
, vol.62
, pp. 925-931
-
-
Cline, J.M.1
Thrall, D.E.2
Page, R.L.3
Franko, A.J.4
Raleigh, J.A.5
-
21
-
-
0032170012
-
Hypoxia and VEGF expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker
-
Raleigh JA, Calkins-Adams DP, Rinker LH, et al. Hypoxia and VEGF expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res. 1998;58:3765-3768.
-
(1998)
Cancer Res
, vol.58
, pp. 3765-3768
-
-
Raleigh, J.A.1
Calkins-Adams, D.P.2
Rinker, L.H.3
-
22
-
-
0030819138
-
Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
-
Bialik S, Greenen DL, Sasson IE, et al. Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Invest. 1997;100:1363-1372.
-
(1997)
J Clin Invest
, vol.100
, pp. 1363-1372
-
-
Bialik, S.1
Greenen, D.L.2
Sasson, I.E.3
-
23
-
-
0026585518
-
Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: Preliminary report of a clinical study
-
Parliament MB, Chapman JD, Urtasun RC, et al. Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical study. Br J Cancer. 1992;65:90-95.
-
(1992)
Br J Cancer
, vol.65
, pp. 90-95
-
-
Parliament, M.B.1
Chapman, J.D.2
Urtasun, R.C.3
-
24
-
-
0031929644
-
Technetium-99m-labeled HL91 to identify tumor hypoxia: Correlation with fluorine-18-FDG
-
Cook GJ, Houston S, Barrington SF, Fogelman I. Technetium-99m-labeled HL91 to identify tumor hypoxia: correlation with fluorine-18-FDG. J Nucl Med. 1998;39:99-103.
-
(1998)
J Nucl Med
, vol.39
, pp. 99-103
-
-
Cook, G.J.1
Houston, S.2
Barrington, S.F.3
Fogelman, I.4
-
25
-
-
0026475672
-
Hypoxia in human gliomas: Demonstration by PET with fluorine-18-fluoromisonidazole
-
Valk PE, Mathis CA, Prados MD, Gilbert JC, Budinger TF. Hypoxia in human gliomas: demonstration by PET with fluorine-18-fluoromisonidazole. J Nucl Med. 1992;33:2133-2137.
-
(1992)
J Nucl Med
, vol.33
, pp. 2133-2137
-
-
Valk, P.E.1
Mathis, C.A.2
Prados, M.D.3
Gilbert, J.C.4
Budinger, T.F.5
-
26
-
-
0029800972
-
Fluorine-18 fluoromisonidazole tumour to muscle retention ratio for the detection of hypoxia in nasopharyngeal carcinoma
-
Yeh SH, Liu RS, Wu LC, et al. Fluorine-18 fluoromisonidazole tumour to muscle retention ratio for the detection of hypoxia in nasopharyngeal carcinoma. Eur J Nucl Med. 1996;23:1378-1383.
-
(1996)
Eur J Nucl Med
, vol.23
, pp. 1378-1383
-
-
Yeh, S.H.1
Liu, R.S.2
Wu, L.C.3
-
30
-
-
0030162585
-
In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia
-
Ballinger JR, Kee JW, Rauth AM. In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia. J Nucl Med. 1996;37:1023-1031.
-
(1996)
J Nucl Med
, vol.37
, pp. 1023-1031
-
-
Ballinger, J.R.1
Kee, J.W.2
Rauth, A.M.3
-
31
-
-
0029145952
-
Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography
-
Koh WJ, Bergman KS, Rasey JS, et al. Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography. Int J Radiat Oncol Biol Phys. 1995;33:391-398.
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.33
, pp. 391-398
-
-
Koh, W.J.1
Bergman, K.S.2
Rasey, J.S.3
-
32
-
-
0030294855
-
Influence of hypoxia on tracer accumulation in squamous-cell carcinoma: In vitro evaluation for PET imaging
-
Minn H, Clavo AC, Wahl RL. Influence of hypoxia on tracer accumulation in squamous-cell carcinoma: in vitro evaluation for PET imaging. Nucl Med Biol. 1996;23:941-946.
-
(1996)
Nucl Med Biol
, vol.23
, pp. 941-946
-
-
Minn, H.1
Clavo, A.C.2
Wahl, R.L.3
-
33
-
-
0030423710
-
Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors
-
Laughlin KM, Evans SM, Jenkins WT, et al. Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors. J Pharmacol Exp Ther. 1996;277:1049-1057.
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 1049-1057
-
-
Laughlin, K.M.1
Evans, S.M.2
Jenkins, W.T.3
-
34
-
-
0029943231
-
The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554
-
Aboagye EO, Lewis AD, Graham MA, et al. The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554. Anticancer Drug Des. 1996;11:231-242.
-
(1996)
Anticancer Drug Des
, vol.11
, pp. 231-242
-
-
Aboagye, E.O.1
Lewis, A.D.2
Graham, M.A.3
-
35
-
-
0019413573
-
SR-2508: A 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use
-
Brown JM, Yu NY, Brown DM, Lee WW. SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use. Int J Radiat Oncol Biol Phys. 1981;7:695-703.
-
(1981)
Int J Radiat Oncol Biol Phys
, vol.7
, pp. 695-703
-
-
Brown, J.M.1
Yu, N.Y.2
Brown, D.M.3
Lee, W.W.4
-
36
-
-
0025810148
-
18F-2-deoxy-2-fluoro-D-glucose uptake into human tumor xenografts: Feasibility studies for cancer imaging with positron-emission tomography
-
18F-2-deoxy-2-fluoro-D-glucose uptake into human tumor xenografts: feasibility studies for cancer imaging with positron-emission tomography. Cancer. 1991;67: 1544-1550.
-
(1991)
Cancer
, vol.67
, pp. 1544-1550
-
-
Wahl, R.L.1
Hutchins, G.D.2
Buchsbaum, D.J.3
Liebert, M.4
Grossman, H.B.5
Fisher, S.6
-
37
-
-
0028304864
-
Active and passive mechanisms of [fluorine-18] fluorodeoxyglucose uptake by proliferating and prenecrotic cancer cells in vivo: A microautoradiographic study
-
Kubota R, Kubota K, Yamada S, Tada M, Ido T, Tamahashi N. Active and passive mechanisms of [fluorine-18] fluorodeoxyglucose uptake by proliferating and prenecrotic cancer cells in vivo: a microautoradiographic study. J Nucl Med. 1994;35:1067-1075.
-
(1994)
J Nucl Med
, vol.35
, pp. 1067-1075
-
-
Kubota, R.1
Kubota, K.2
Yamada, S.3
Tada, M.4
Ido, T.5
Tamahashi, N.6
-
38
-
-
0027489631
-
Fluorodeoxyglucose cell incorporation as an index of cell proliferation: Evaluation of accuracy in cell culture
-
Slosman DO, Pittet N, Donath A, Polla BS. Fluorodeoxyglucose cell incorporation as an index of cell proliferation: evaluation of accuracy in cell culture. Eur J Nucl Med. 1993;20:1084-1088.
-
(1993)
Eur J Nucl Med
, vol.20
, pp. 1084-1088
-
-
Slosman, D.O.1
Pittet, N.2
Donath, A.3
Polla, B.S.4
-
39
-
-
0027182896
-
Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles: Implications for use as hypoxic cell markers
-
Koch CJ, Giandomenico AR, Iyengar CW. Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles: implications for use as hypoxic cell markers. Biochem Pharmacol. 1993;46:1029-1036.
-
(1993)
Biochem Pharmacol.
, vol.46
, pp. 1029-1036
-
-
Koch, C.J.1
Giandomenico, A.R.2
Iyengar, C.W.3
-
40
-
-
0029802773
-
Pharmacokinetics of SPECT radiopharmaceuticals for imaging hypoxic tissues
-
Wiebe LI, Stypinski D. Pharmacokinetics of SPECT radiopharmaceuticals for imaging hypoxic tissues. Q J Nucl Med. 1996;40:270-284.
-
(1996)
Q J Nucl Med
, vol.40
, pp. 270-284
-
-
Wiebe, L.I.1
Stypinski, D.2
|