Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing neoadjuvant chemoradiotherapy for rectal carcinoma: A pilot study

Diseases of the Colon and Rectum

Volumn 51, Issue 11, 2008, Pages 1641-1648

  Dietz, David W ^a,e   Dehdashti, Farrokh ^b,c   Grigsby, Perry W ^c,d   Malyapa, Robert S ^c,d   Myerson, Robert J ^c,d   Picus, Joel ^c,d   Ritter, Jon ^d   Lewis, Jason S ^b,c   Welch, Michael J ^b,c   Siegel, Barry A ^b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c USA   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NONE   (United States)

Author keywords

Cu ATSM; Neoadjuvant therapy; Positron emission tomography; Rectal cancer; Tumor hypoxia; Tumor response

Indexed keywords

DIACETYL BIS(N 4 METHYLTHIOSEMICARBAZONE) CU 60; FLUORODEOXYGLUCOSE F 18; FLUOROURACIL; TRACER; UNCLASSIFIED DRUG;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CANCER INVASION; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ACCUMULATION; ECHOGRAPHY; FEMALE; HUMAN; HYPOXIA; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PILOT STUDY; POSITRON EMISSION TOMOGRAPHY; PROGNOSIS; RADIATION DOSE; RECTUM CARCINOMA; RECTUM RESECTION; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR HYPOXIA;

ADULT; AGED; CARCINOMA; CELL HYPOXIA; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; ORGANOMETALLIC COMPOUNDS; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECTAL NEOPLASMS; THIOSEMICARBAZONES;

EID: 54949157918     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-008-9420-3     Document Type: Article

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