메뉴 건너뛰기




Volumn 40, Issue 1, 1999, Pages 177-183

Evaluation of 64Cu-ATSM in vitro and in vivo in a hypoxic tumor model

Author keywords

60Cu; 64Cu; ATSM; EMT6; Hypoxia

Indexed keywords

COPPER 64; COPPER DERIVATIVE; COPPER DIACETYL BIS(N4 MEHTHYLTHIOSEMICARBAZONE); UNCLASSIFIED DRUG; 1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; COPPER (II) DIACETYL DI(N(4) METHYLTHIOSEMICARBAZONE); COPPER (II) DIACETYL-DI(N(4)-METHYLTHIOSEMICARBAZONE); COPPER PYRUVALDEHYDE BIS(N(4) METHYLTHIOSEMICARBAZONE) COMPLEX; COPPER PYRUVALDEHYDE BIS(N(4)-METHYLTHIOSEMICARBAZONE) COMPLEX; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MISONIDAZOLE; ORGANOMETALLIC COMPOUND; OXYGEN; THIOSEMICARBAZONE DERIVATIVE;

EID: 0032587218     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (330)

References (41)
  • 1
    • 0023910405 scopus 로고
    • Hypoxia in tumors: A paradigm for the approach to biochemical and physiological heterogeneity
    • Coleman CN. Hypoxia in tumors: a paradigm for the approach to biochemical and physiological heterogeneity. J Natl Cancer Inst. 1988;80:310-317.
    • (1988) J Natl Cancer Inst. , vol.80 , pp. 310-317
    • Coleman, C.N.1
  • 3
    • 0345719653 scopus 로고
    • Tumor hypoxia: Its impact on cancer therapy
    • Moulder JE, Rockwell S. Tumor hypoxia: its impact on cancer therapy. Br J Radiol. 1987;26:638-648.
    • (1987) Br J Radiol. , vol.26 , pp. 638-648
    • Moulder, J.E.1    Rockwell, S.2
  • 4
    • 0023798415 scopus 로고
    • Preclinical studies of porfiromycin as an adjunct to radiotherapy
    • Rockwell S, Keyes SR, Sartorelli AC. Preclinical studies of porfiromycin as an adjunct to radiotherapy. Radiat Res. 1988;116:100-113.
    • (1988) Radiat Res. , vol.116 , pp. 100-113
    • Rockwell, S.1    Keyes, S.R.2    Sartorelli, A.C.3
  • 5
    • 0022474587 scopus 로고
    • Effect of some proliferative and environmental factors on the toxicity of mitomycin C to tumor cells in vitro
    • Rockwell S. Effect of some proliferative and environmental factors on the toxicity of mitomycin C to tumor cells in vitro. Int J Cancer. 1986;38:229-235.
    • (1986) Int J Cancer , vol.38 , pp. 229-235
    • Rockwell, S.1
  • 8
    • 0029027880 scopus 로고
    • Kinetic analysis of technetium-99m-labeled nitromidazole (BMS181321) as a tracer of myocardial hypoxia
    • Ng CK, Sinusas AJ, Zaret B, Souter R. Kinetic analysis of technetium-99m-labeled nitromidazole (BMS181321) as a tracer of myocardial hypoxia. Circulation. 1995;92:1261-1268.
    • (1995) Circulation. , vol.92 , pp. 1261-1268
    • Ng, C.K.1    Sinusas, A.J.2    Zaret, B.3    Souter, R.4
  • 9
    • 0028905191 scopus 로고
    • Effect of graded hypoxia in retention of technetium-99m-nitroheterocycle in perfused rat hearts
    • Rumsey WL, Patel B, Linder K. Effect of graded hypoxia in retention of technetium-99m-nitroheterocycle in perfused rat hearts. J Nucl Med. 1995;36:632-636.
    • (1995) J Nucl Med. , vol.36 , pp. 632-636
    • Rumsey, W.L.1    Patel, B.2    Linder, K.3
  • 11
    • 0030162585 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia
    • Ballinger JR, Wan Min Kee J, Rauth AM. In vitro and in vivo evaluation of a technetium-99m-labeled 2-nitroimidazole (BMS181321) as a marker of tumor hypoxia. J Nucl Med. 1996;37:1023-1031.
    • (1996) J Nucl Med. , vol.37 , pp. 1023-1031
    • Ballinger, J.R.1    Wan Min Kee, J.2    Rauth, A.M.3
  • 12
    • 0031929644 scopus 로고    scopus 로고
    • Technetium-99m-labeled HL91 to identify tumor hypoxia: Correlation with fluorine-18-FDG
    • Cook GJR, Houston S, Barrington SF, Fogelman I. Technetium-99m-labeled HL91 to identify tumor hypoxia: correlation with fluorine-18-FDG. J Nucl Med. 1998;39:99-103.
    • (1998) J Nucl Med. , vol.39 , pp. 99-103
    • Cook, G.J.R.1    Houston, S.2    Barrington, S.F.3    Fogelman, I.4
  • 13
    • 0030292909 scopus 로고    scopus 로고
    • Copper radionuclides and radiopharmaceuticals in nuclear medicine
    • Blower PJ, Lewis JS, Zweit J. Copper radionuclides and radiopharmaceuticals in nuclear medicine. Nucl Med Biol. 1996;23:957-980.
    • (1996) Nucl Med Biol. , vol.23 , pp. 957-980
    • Blower, P.J.1    Lewis, J.S.2    Zweit, J.3
  • 14
    • 0030838026 scopus 로고    scopus 로고
    • Hyperfixation of copper-62-PTSM in rat brain after transient global ischemia
    • Taniuchi H, Fujibayashi Y, Yonekura Y, Konishi J, Yokoyama A. Hyperfixation of copper-62-PTSM in rat brain after transient global ischemia. J Nucl Med. 1997;38:1130-1134.
    • (1997) J Nucl Med. , vol.38 , pp. 1130-1134
    • Taniuchi, H.1    Fujibayashi, Y.2    Yonekura, Y.3    Konishi, J.4    Yokoyama, A.5
  • 15
    • 0030811565 scopus 로고    scopus 로고
    • Copper-62-ATSM: A new hypoxia imaging agent with high membrane permeability and low redox potential
    • Fujibayashi Y, Taniuchi H, Yonekura Y, Ohtani H, Konishi J, Yokoyama A. Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential. J Nucl Med. 1997;38:1155-1160.
    • (1997) J Nucl Med. , vol.38 , pp. 1155-1160
    • Fujibayashi, Y.1    Taniuchi, H.2    Yonekura, Y.3    Ohtani, H.4    Konishi, J.5    Yokoyama, A.6
  • 16
    • 0002266827 scopus 로고    scopus 로고
    • Evaluation of copper-62 ATSM in patients with lung cancer as a hypoxic tissue tracer
    • Takahashi N, Fujibayashi Y, Yonekura Y, et al. Evaluation of copper-62 ATSM in patients with lung cancer as a hypoxic tissue tracer [Abstract]. J Nucl Med. 1998;39:53P.
    • (1998) J Nucl Med. , vol.39
    • Takahashi, N.1    Fujibayashi, Y.2    Yonekura, Y.3
  • 18
    • 0000444951 scopus 로고    scopus 로고
    • High purity production and potential applications of copper-60 and copper-61
    • Bass LA, McCarthy DW, Jones LA, et al. High purity production and potential applications of copper-60 and copper-61. J Label Comp Radiopharm. 1997;40:325-327.
    • (1997) J Label Comp Radiopharm. , vol.40 , pp. 325-327
    • Bass, L.A.1    McCarthy, D.W.2    Jones, L.A.3
  • 20
    • 0345288000 scopus 로고    scopus 로고
    • 64Cu-ATSM a hypoxia imaging agent and C-11-acetate in an acute myocardial infarction model: Ex vivo imaging in rats
    • in press
    • 64Cu-ATSM a hypoxia imaging agent and C-11-acetate in an acute myocardial infarction model: ex vivo imaging in rats. Nucl Med Biol. in press.
    • Nucl Med Biol.
    • Fujibayashi, Y.1    Cutler, C.S.2    Anderson, C.J.3
  • 21
    • 85047671244 scopus 로고
    • Evaluation of copper(II)-pyruvaldehyde bis(N-4-methylthiosemicarbazone) for tissue blood flow measurement using a trapped tracer model
    • Young H, Carnochan P, Zweit J, Babich J, Cherry S, Ott R. Evaluation of copper(II)-pyruvaldehyde bis(N-4-methylthiosemicarbazone) for tissue blood flow measurement using a trapped tracer model. J Nucl Med. 1994;21:336-341.
    • (1994) J Nucl Med. , vol.21 , pp. 336-341
    • Young, H.1    Carnochan, P.2    Zweit, J.3    Babich, J.4    Cherry, S.5    Ott, R.6
  • 23
    • 0031869326 scopus 로고    scopus 로고
    • Design of hypoxia-targeting radiopharmaceuticals: Selective uptake of copper-64 complexes in hypoxic cells in vitro
    • Dearling JLD, Lewis JS, Mullen GED, Rae MT, Zweit J, Blower PJ. Design of hypoxia-targeting radiopharmaceuticals: Selective uptake of copper-64 complexes in hypoxic cells in vitro. Eur J Nucl Med. 1998;25:788-792.
    • (1998) Eur J Nucl Med. , vol.25 , pp. 788-792
    • Dearling, J.L.D.1    Lewis, J.S.2    Mullen, G.E.D.3    Rae, M.T.4    Zweit, J.5    Blower, P.J.6
  • 24
    • 0023115258 scopus 로고
    • 4-methylthiosemicarbazone)
    • 4-methylthiosemicarbazone). Nucl Med Biol. 1987;14:59-61.
    • (1987) Nucl Med Biol. , vol.14 , pp. 59-61
    • Green, M.A.1
  • 25
    • 0025604804 scopus 로고
    • 4-methylthiosemicarbazone)copper(II): Synthesis and evaluation as a positron emission tomography tracer for cerebral and myocardial perfusion
    • 4-methylthiosemicarbazone)copper(II): synthesis and evaluation as a positron emission tomography tracer for cerebral and myocardial perfusion. J Nucl Med. 1990;31:1989-1996.
    • (1990) J Nucl Med. , vol.31 , pp. 1989-1996
    • Green, M.A.1    Mathias, C.J.2    Welch, M.J.3
  • 26
    • 44949283821 scopus 로고
    • Investigation of copper-PTSM as a PET tracer for tumor blood flow
    • Mathias CJ, Welch MJ, Perry DJ, et al. Investigation of copper-PTSM as a PET tracer for tumor blood flow. Nucl Med Biol. 1991;18:807-811.
    • (1991) Nucl Med Biol. , vol.18 , pp. 807-811
    • Mathias, C.J.1    Welch, M.J.2    Perry, D.J.3
  • 27
    • 0029093125 scopus 로고
    • 4-methylthiosemicarbazone) (Cu-PTSM), a metal complex with selective NADH-dependent reduction by complex I in brain mitochondria: A potential radiopharmaceutical for mitochondria-functional imaging with positron emission tomography
    • 4-methylthiosemicarbazone) (Cu-PTSM), a metal complex with selective NADH-dependent reduction by complex I in brain mitochondria: a potential radiopharmaceutical for mitochondria-functional imaging with positron emission tomography. Biol Pharm Bull. 1995;18:1126-1129.
    • (1995) Biol Pharm Bull. , vol.18 , pp. 1126-1129
    • Taniuchi, H.1    Fujibayashi, Y.2    Okazawa, H.3    Yonekura, Y.4    Konishi, J.5    Yokoyama, A.6
  • 28
    • 0026570515 scopus 로고
    • Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole
    • Koh W-J, Rasey JS, Evans ML. Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole. Int J Radiat Oncol Biol Phys. 1992;22:199-212.
    • (1992) Int J Radiat Oncol Biol Phys. , vol.22 , pp. 199-212
    • Koh, W.-J.1    Rasey, J.S.2    Evans, M.L.3
  • 29
    • 0024562711 scopus 로고
    • Myocardial kinetics of fluorine-18 misonidazole: A marker of hypoxic myocardium
    • Shelton ME, Dence C, Hwang D-R, Welch MJ. Myocardial kinetics of fluorine-18 misonidazole: a marker of hypoxic myocardium. J Nucl Med. 1989;30:351-358.
    • (1989) J Nucl Med. , vol.30 , pp. 351-358
    • Shelton, M.E.1    Dence, C.2    Hwang, D.-R.3    Welch, M.J.4
  • 30
    • 0026471986 scopus 로고
    • Non-invasive detection of hypoxic myocardium using fluorine-18-fluoromisonidazole and positron emission tomography
    • Martin GV, Caldwell JH, Graham MM, et al. Non-invasive detection of hypoxic myocardium using fluorine-18-fluoromisonidazole and positron emission tomography. J Nucl Med. 1992;33:2202-2208.
    • (1992) J Nucl Med. , vol.33 , pp. 2202-2208
    • Martin, G.V.1    Caldwell, J.H.2    Graham, M.M.3
  • 31
    • 0017603563 scopus 로고
    • In vivo-in vitro tumor systems: New models for studying the response of tumors to therapy
    • Rockwell S. In vivo-in vitro tumor systems: new models for studying the response of tumors to therapy. Lab Animal Sci. 1977;27:831-851.
    • (1977) Lab Animal Sci. , vol.27 , pp. 831-851
    • Rockwell, S.1
  • 32
    • 0023232996 scopus 로고
    • Evaluation of various types of new hypoxic cell sensitizers using the EMT6 single cell-spheroid-solid tumor system
    • Shibamoto Y, Nishimoto S, Mi F, Sasai K, Kagiya T, Abe M. Evaluation of various types of new hypoxic cell sensitizers using the EMT6 single cell-spheroid-solid tumor system. Int J Radiat Biol. 1987;52:347-357.
    • (1987) Int J Radiat Biol. , vol.52 , pp. 347-357
    • Shibamoto, Y.1    Nishimoto, S.2    Mi, F.3    Sasai, K.4    Kagiya, T.5    Abe, M.6
  • 33
    • 0021853478 scopus 로고
    • Hypoxic fraction and binding of misonidazole in EMT6/Ed multicellular tumor spheroids
    • Franko AJ. Hypoxic fraction and binding of misonidazole in EMT6/Ed multicellular tumor spheroids. Radiat Res. 1985;103:89-97.
    • (1985) Radiat Res. , vol.103 , pp. 89-97
    • Franko, A.J.1
  • 34
    • 0021276479 scopus 로고
    • Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data
    • Moulder JE, Rockwell S. Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int J Radiat Oncol Biol Phys. 1984;10:695-712.
    • (1984) Int J Radiat Oncol Biol Phys. , vol.10 , pp. 695-712
    • Moulder, J.E.1    Rockwell, S.2
  • 36
    • 0025285228 scopus 로고
    • Characteristics of the binding of labeled fluoromisonidazole in cells in vitro
    • Rasey JS, Nelson NJ, Chin L, Evans ML, Grunbaum Z. Characteristics of the binding of labeled fluoromisonidazole in cells in vitro. Radiation Res. 1990;122: 301-308.
    • (1990) Radiation Res. , vol.122 , pp. 301-308
    • Rasey, J.S.1    Nelson, N.J.2    Chin, L.3    Evans, M.L.4    Grunbaum, Z.5
  • 37
    • 0017874247 scopus 로고
    • Structure-function correlations in the reaction of bis(thiosemicarbazonato) copper(II) complexes with Ehrlich ascites tumor cells
    • Minkel DT, Saryan LA, Petering DH. Structure-function correlations in the reaction of bis(thiosemicarbazonato) copper(II) complexes with Ehrlich ascites tumor cells. Cancer Res. 1978;38:124-129.
    • (1978) Cancer Res. , vol.38 , pp. 124-129
    • Minkel, D.T.1    Saryan, L.A.2    Petering, D.H.3
  • 39
    • 0017710459 scopus 로고
    • Evaluation of cardiac ischemia by NADH fluorescence photography
    • Barlow CH, Harken AH, Chance B. Evaluation of cardiac ischemia by NADH fluorescence photography. Ann Surg. 1977;186:737-740.
    • (1977) Ann Surg. , vol.186 , pp. 737-740
    • Barlow, C.H.1    Harken, A.H.2    Chance, B.3
  • 40
    • 44949285173 scopus 로고
    • The effects of glutathione depletion on the biodistribution of Cu(PTSM) in rats
    • Barnhart-Bott A, Green MA. The effects of glutathione depletion on the biodistribution of Cu(PTSM) in rats. Nucl Med Biol. 1991;18:865-869.
    • (1991) Nucl Med Biol. , vol.18 , pp. 865-869
    • Barnhart-Bott, A.1    Green, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.