메뉴 건너뛰기




Volumn 1187, Issue , 2010, Pages 218-246

Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs

Author keywords

Amphetamine; Cocaine; Knockout; Psychostimulant; Transgenic

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; AMPHETAMINE; COCAINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE 5 RECEPTOR; DOPAMINE TRANSPORTER; METHYLPHENIDATE; NORADRENALIN; NORADRENALIN TRANSPORTER; PSYCHOSTIMULANT AGENT; SEROTONIN 1B RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 77949301555     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05276.x     Document Type: Review
Times cited : (35)

References (188)
  • 1
    • 0031030042 scopus 로고    scopus 로고
    • Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
    • Sora, I. et al. 1997. Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc. Natl. Acad. Sci. USA 94: 1544-1549.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1544-1549
    • Sora, I.1
  • 2
    • 0030931721 scopus 로고    scopus 로고
    • VMAT2 knockout mice: Heterozygotes display reduced amphetamine- conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity
    • Takahashi, N. et al. 1997. VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc. Natl. Acad. Sci. USA 94: 9938-9943.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9938-9943
    • Takahashi, N.1
  • 3
    • 0032560560 scopus 로고    scopus 로고
    • Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice
    • Sora, I. et al. 1998.Cocaine rewardmodels: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc. Natl. Acad. Sci. USA 95: 7699-7704.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7699-7704
    • Sora, I.1
  • 4
    • 0033118963 scopus 로고    scopus 로고
    • Identifying genes for alcohol and drug sensitivity: Recent progress and future directions
    • Crabbe, J.C. et al. 1999. Identifying genes for alcohol and drug sensitivity: recent progress and future directions. Trends Neurosci. 22: 173-179.
    • (1999) Trends Neurosci , vol.22 , pp. 173-179
    • Crabbe, J.C.1
  • 5
    • 85047700129 scopus 로고    scopus 로고
    • Cocaine, reward, movement and monoamine transporters
    • Uhl, G.R., F.S. Hall & I. Sora. 2002. Cocaine, reward, movement and monoamine transporters. Mol. Psychiatry 7: 21-26.
    • (2002) Mol. Psychiatry , vol.7 , pp. 21-26
    • Uhl, G.R.1    Hall, F.S.2    Sora, I.3
  • 6
    • 0033664390 scopus 로고    scopus 로고
    • The VMAT2 gene in mice and humans: Amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins
    • Uhl, G.R. et al. 2000. The VMAT2 gene in mice and humans: amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins. FASEB J. 14: 2459-2465.
    • (2000) FASEB J , vol.14 , pp. 2459-2465
    • Uhl, G.R.1
  • 7
    • 0025855256 scopus 로고
    • The dopamine hypothesis of the reinforcing properties of cocaine
    • Kuhar, M.J.,M.C.Ritz&J.W. Boja. 1991. The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci. 14: 299-302.
    • (1991) Trends Neurosci , vol.14 , pp. 299-302
    • Kuhar, M.J.1    Ritz, M.C.2    Boja, J.W.3
  • 8
    • 0032213002 scopus 로고    scopus 로고
    • Genetic and environmental influences on drug use and abuse/dependence in male and female twins
    • Van Den Bree, M.B. et al. 1998. Genetic and environmental influences on drug use and abuse/dependence in male and female twins. Drug Alcohol Depend. 52: 231-241.
    • (1998) Drug Alcohol Depend , vol.52 , pp. 231-241
    • Van Den Bree, M.B.1
  • 9
    • 10744226608 scopus 로고    scopus 로고
    • Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis
    • Ujike, H. et al. 2003. Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis. Pharmacogenomics J. 3: 242-247.
    • (2003) Pharmacogenomics J , vol.3 , pp. 242-247
    • Ujike, H.1
  • 10
    • 0032082917 scopus 로고    scopus 로고
    • Cocaine self-administration in dopamine-transporter knockout mice
    • Rocha, B.A. et al. 1998. Cocaine self-administration in dopamine-transporter knockout mice. Nat. Neurosci. 1: 132-137.
    • (1998) Nat. Neurosci. , vol.1 , pp. 132-137
    • Rocha, B.A.1
  • 11
    • 21344442897 scopus 로고    scopus 로고
    • Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice
    • Medvedev, I.O. et al. 2005. Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice. Psychopharmacology (Berl) 180: 408-413.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 408-413
    • Medvedev, I.O.1
  • 12
    • 3142691054 scopus 로고    scopus 로고
    • Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background
    • Morice, E. et al. 2004. Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background. Eur. J. Neurosci. 20: 120-126.
    • (2004) Eur. J. Neurosci , vol.20 , pp. 120-126
    • Morice, E.1
  • 13
    • 51849123246 scopus 로고    scopus 로고
    • Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats
    • Homberg, J.R. et al. 2008. Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats. Psychopharmacology (Berl) 200: 367-380.
    • (2008) Psychopharmacology (Berl) , vol.200 , pp. 367-380
    • Homberg, J.R.1
  • 14
    • 0032966857 scopus 로고    scopus 로고
    • RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: An effect reversed by GR 127935, a 5-HT1B/1D antagonist
    • Harrison, A.A. et al. 1999. RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist. Psychopharmacology (Berl) 141: 242-250.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 242-250
    • Harrison, A.A.1
  • 15
    • 0032516173 scopus 로고    scopus 로고
    • Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor
    • Rocha, B.A. et al. 1998. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature 393: 175-178.
    • (1998) Nature , vol.393 , pp. 175-178
    • Rocha, B.A.1
  • 16
    • 0035942241 scopus 로고    scopus 로고
    • Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
    • Sora, I. et al. 2001. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc. Natl. Acad. Sci. USA 98: 5300-5305.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5300-5305
    • Sora, I.1
  • 17
    • 0033915420 scopus 로고    scopus 로고
    • Mice lacking the norepinephrine transporter are supersensitive to psychostimulants
    • Xu, F. et al. 2000. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants.Nat. Neurosci. 3: 465-471.
    • (2000) Nat. Neurosci. , vol.3 , pp. 465-471
    • Xu, F.1
  • 18
    • 0037110603 scopus 로고    scopus 로고
    • Cocaine mechanisms: Enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions
    • Hall, F.S. et al. 2002. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115: 153-161.
    • (2002) Neuroscience , vol.115 , pp. 153-161
    • Hall, F.S.1
  • 19
    • 59649128018 scopus 로고    scopus 로고
    • Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice
    • Thomsen, M. et al. 2009. Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice. J. Neurosci. 29: 1087-1092.
    • (2009) J. Neurosci , vol.29 , pp. 1087-1092
    • Thomsen, M.1
  • 20
    • 5044225659 scopus 로고    scopus 로고
    • Regional differences in extra cellular dopamine and serotonin assessed by in vivo micro dialysis in mice lacking dopamine and/or serotonin transporters
    • Shen, H.W. et al. 2004. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology 29: 1790-1799.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1790-1799
    • Shen, H.W.1
  • 21
    • 0005231099 scopus 로고    scopus 로고
    • Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene
    • Carboni, E. et al. 2001. Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene. J. Neurosci. 21: 1-4.
    • (2001) J. Neurosci , vol.21 , pp. 1-4
    • Carboni, E.1
  • 22
    • 1642543988 scopus 로고    scopus 로고
    • Genetic and pharmacological manipulation of mu opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine
    • Hummel, M. et al. 2004. Genetic and pharmacological manipulation of mu opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine. Neuroscience 125: 211-220.
    • (2004) Neuroscience , vol.125 , pp. 211-220
    • Hummel, M.1
  • 23
    • 0032721505 scopus 로고    scopus 로고
    • Cocaine reward and MPTP toxicity: Alteration by regional variant dopamine transporter overexpression
    • Donovan, D.M. et al. 1999. Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain Res. Mol. Brain Res. 73: 37-49.
    • (1999) Brain Res. Mol. Brain Res , vol.73 , pp. 37-49
    • Donovan, D.M.1
  • 25
    • 0035852691 scopus 로고    scopus 로고
    • Hyperactivity and impaired response habituation in hyperdopaminergic mice
    • Zhuang, X. et al. 2001. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proc. Natl. Acad. Sci. USA 98: 1982-1987.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1982-1987
    • Zhuang, X.1
  • 26
    • 34447532025 scopus 로고    scopus 로고
    • Cocaine reward and locomotion stimulation in micewith reduced dopamine transporter expression
    • Tilley,M.R. et al. 2007.Cocaine reward and locomotion stimulation in micewith reduced dopamine transporter expression. BMC Neurosci. 8: 42.
    • (2007) BMC Neurosci , vol.8 , pp. 42
    • Tilley, M.R.1
  • 27
    • 0031458923 scopus 로고    scopus 로고
    • Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine
    • Wang, Y.M. et al. 1997. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron 19: 1285-1296.
    • (1997) Neuron , vol.19 , pp. 1285-1296
    • Wang, Y.M.1
  • 28
    • 34547449724 scopus 로고    scopus 로고
    • Genetic deletion of vesicular monoamine transporter-2 (VMAT2) reduces dopamine transporter activity in mesencephalic neurons in primary culture
    • Yamamoto, H. et al. 2007. Genetic deletion of vesicular monoamine transporter-2 (VMAT2) reduces dopamine transporter activity in mesencephalic neurons in primary culture. Neurochem. Int. 51: 237-244.
    • (2007) Neurochem. Int. , vol.51 , pp. 237-244
    • Yamamoto, H.1
  • 29
    • 34248594440 scopus 로고    scopus 로고
    • Increased dopamine D2High receptors in knockouts of the dopamine transporter and the vesicular monoamine transporter may contribute to spontaneous hyperactivity and dopamine supersensitivity
    • Seeman, P., F.S. Hall & G. Uhl. 2007. Increased dopamine D2High receptors in knockouts of the dopamine transporter and the vesicular monoamine transporter may contribute to spontaneous hyperactivity and dopamine supersensitivity. Synapse 61: 573-576.
    • (2007) Synapse , vol.61 , pp. 573-576
    • Seeman, P.1    Hall, F.S.2    Uhl, G.3
  • 30
    • 63049115144 scopus 로고    scopus 로고
    • Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals
    • Seeman, P. 2009. Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals. Synapse 63: 186-192.
    • (2009) Synapse , vol.63 , pp. 186-192
    • Seeman, P.1
  • 31
    • 33745165213 scopus 로고    scopus 로고
    • Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter
    • Chen, R. et al. 2006. Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter. Proc. Natl. Acad. Sci. USA 103: 9333-9338.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9333-9338
    • Chen, R.1
  • 32
    • 58149271123 scopus 로고    scopus 로고
    • Cocaine does not produce reward in absence of dopamine transporter inhibition
    • Tilley, M.R. et al. 2009. Cocaine does not produce reward in absence of dopamine transporter inhibition. Neuroreport 20: 9-12.
    • (2009) Neuroreport , vol.20 , pp. 9-12
    • Tilley, M.R.1
  • 33
    • 70349330686 scopus 로고    scopus 로고
    • Lack of cocaine selfadministration in mice expressing a cocaine-insensitive dopamine transporter
    • Thomsen, M. et al. 2009. Lack of cocaine selfadministration in mice expressing a cocaine-insensitive dopamine transporter. J. Pharmacol. Exp. Ther. 331: 204-211.
    • (2009) J. Pharmacol. Exp. Ther , vol.331 , pp. 204-211
    • Thomsen, M.1
  • 34
    • 49949091073 scopus 로고    scopus 로고
    • Dopamine transporter inhibition is required for cocaine-induced stereotypy
    • Tilley, M.R. & H.H. Gu. 2008. Dopamine transporter inhibition is required for cocaine-induced stereotypy. Neuroreport 19: 1137-1140.
    • (2008) Neuroreport , vol.19 , pp. 1137-1140
    • Tilley, M.R.1    Gu, H.H.2
  • 35
    • 0345305851 scopus 로고    scopus 로고
    • Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders
    • Murphy,D.L. et al. 2003. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes Brain Behav. 2: 350-364.
    • (2003) Genes Brain Behav , vol.2 , pp. 350-364
    • Murphy, D.L.1
  • 36
    • 0347088966 scopus 로고    scopus 로고
    • Role of serotonin in cocaine effects in mice with reduced dopamine transporter function
    • Mateo, Y. et al. 2004. Role of serotonin in cocaine effects in mice with reduced dopamine transporter function. Proc. Natl. Acad. Sci. USA 101: 372-377.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 372-377
    • Mateo, Y.1
  • 37
    • 36248940286 scopus 로고    scopus 로고
    • Cocaine-conditioned place preference by dopaminedeficient mice ismediated by serotonin
    • Hnasko, T.S., B.N. Sotak & R.D. Palmiter. 2007. Cocaine-conditioned place preference by dopaminedeficient mice ismediated by serotonin. J. Neurosci. 27: 12484-12488.
    • (2007) J. Neurosci , vol.27 , pp. 12484-12488
    • Hnasko, T.S.1    Sotak, B.N.2    Palmiter, R.D.3
  • 38
    • 4444249161 scopus 로고    scopus 로고
    • Firing properties of dopamine neurons in freely moving dopamine-deficient mice: Effects of dopamine receptor activation and anesthesia
    • Robinson, S. et al. 2004. Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia. Proc. Natl. Acad. Sci. USA 101: 13329-13334.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 13329-13334
    • Robinson, S.1
  • 39
    • 0022725590 scopus 로고
    • Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
    • Robinson,T.E.&J.B. Becker. 1986. Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animalmodels of amphetamine psychosis. Brain Res. 396: 157-198.
    • (1986) Brain Res , vol.396 , pp. 157-198
    • Robinson, T.E.1    Becker, J.B.2
  • 40
    • 0027184879 scopus 로고
    • The pharmacology and neural circuitry of sensitization to psychostimulants
    • Kalivas, P.W., B.A. Sorg & M.S. Hooks. 1993. The pharmacology and neural circuitry of sensitization to psychostimulants. Behav. Pharmacol. 4: 315-334.
    • (1993) Behav. Pharmacol. , vol.4 , pp. 315-334
    • Kalivas, P.W.1    Sorg, B.A.2    Hooks, M.S.3
  • 41
    • 0025751604 scopus 로고
    • Dopamine transmission in the initiation and expression of drug- and stressinduced sensitization of motor activity
    • Kalivas, P.W. & J. Stewart. 1991. Dopamine transmission in the initiation and expression of drug- and stressinduced sensitization of motor activity. Brain Res. Brain Res. Rev. 16: 223-244.
    • (1991) Brain Res. Brain Res. Rev , vol.16 , pp. 223-244
    • Kalivas, P.W.1    Stewart, J.2
  • 42
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros, B. et al. 1996. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379: 606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1
  • 43
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov, R.R. et al. 1999. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283: 397-401.
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1
  • 44
    • 0036460381 scopus 로고    scopus 로고
    • Intravenous cocaine induced-activity and behavioural sensitization in norepinephrine-, but not dopamine-transporter knockout mice
    • Mead, A.N. et al. 2002. Intravenous cocaine induced-activity and behavioural sensitization in norepinephrine-, but not dopamine-transporter knockout mice. Eur. J. Neurosci. 16: 514-520.
    • (2002) Eur. J. Neurosci , vol.16 , pp. 514-520
    • Mead, A.N.1
  • 45
    • 33749552018 scopus 로고    scopus 로고
    • Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo
    • Drgon, T. et al. 2006. Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo. Cell Mol. Neurobiol. 26: 875-889.
    • (2006) Cell Mol. Neurobiol , vol.26 , pp. 875-889
    • Drgon, T.1
  • 46
    • 67949114085 scopus 로고    scopus 로고
    • Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice
    • Hall, F.S. et al. 2009. Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice. Neuroscience. 16: 870-880.
    • (2009) Neuroscience , vol.16 , pp. 870-880
    • Hall, F.S.1
  • 47
    • 45849106857 scopus 로고    scopus 로고
    • Dopamine transporter mutant mice inexperimental neuropharmacology
    • Gainetdinov, R.R. 2008. Dopamine transporter mutant mice inexperimentalneuropharmacology.Naunyn Schmiedebergs Arch. Pharmacol. 377: 301-313.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.377 , pp. 301-313
    • Gainetdinov, R.R.1
  • 48
    • 0035125656 scopus 로고    scopus 로고
    • Genetics of childhood disorders: XXIV. ADHD, part 8: Hyperdopaminergic mice as an animal model of ADHD
    • Gainetdinov, R.R. & M.G. Caron. 2001. Genetics of childhood disorders: XXIV. ADHD, part 8: hyperdopaminergic mice as an animal model of ADHD. J. Am. Acad. Child Adolesc. Psychiatry 40: 380-382.
    • (2001) J. Am. Acad. Child Adolesc. Psychiatry , vol.40 , pp. 380-382
    • Gainetdinov, R.R.1    Caron, M.G.2
  • 49
    • 0842264904 scopus 로고    scopus 로고
    • The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice
    • Barr, A.M. et al. 2004. The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology 29: 221-228.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 221-228
    • Barr, A.M.1
  • 50
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists
    • Ralph, R.J. et al. 2001. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J. Neurosci. 21: 305-313.
    • (2001) J. Neurosci , vol.21 , pp. 305-313
    • Ralph, R.J.1
  • 51
    • 33748808963 scopus 로고    scopus 로고
    • Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice
    • Yamashita, M. et al. 2006. Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice. Neuropsychopharmacology 31: 2132-2139.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2132-2139
    • Yamashita, M.1
  • 52
    • 0025061257 scopus 로고
    • Blockade of the noradrenaline carrier increases extra cellular dopamine concentrations in the prefrontal cortex: Evidence that dopamine is taken up in vivo by noradrenergic terminals
    • Carboni, E. et al. 1990. Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals. J. Neurochem. 55: 1067-1070.
    • (1990) J. Neurochem , vol.55 , pp. 1067-1070
    • Carboni, E.1
  • 53
    • 0037080158 scopus 로고    scopus 로고
    • Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: Evidence from knock-out mouse lines
    • Moron, J.A. et al. 2002. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J. Neurosci. 22: 389-395.
    • (2002) J. Neurosci , vol.22 , pp. 389-395
    • Moron, J.A.1
  • 54
    • 0022896790 scopus 로고
    • Acute cardiac events temporally related to cocaine abuse
    • Isner, J.M. et al. 1986. Acute cardiac events temporally related to cocaine abuse. N. Engl. J. Med. 315: 1438-1443.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1438-1443
    • Isner, J.M.1
  • 55
    • 0027519857 scopus 로고
    • Seizures associated with poisoning and drug overdose
    • Olson, K.R. et al. 1993. Seizures associated with poisoning and drug overdose.Am. J. Emerg. Med. 11: 565-568.
    • (1993) Am. J. Emerg. Med. , vol.11 , pp. 565-568
    • Olson, K.R.1
  • 56
    • 19444368025 scopus 로고    scopus 로고
    • Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures
    • Kaminski, R.M. et al. 2005. Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures. Neurosci. Lett. 382: 51-55.
    • (2005) Neurosci. Lett. , vol.382 , pp. 51-55
    • Kaminski, R.M.1
  • 57
    • 33646073783 scopus 로고    scopus 로고
    • Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs
    • Han, D.D. & H.H. Gu. 2006. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs.BMCPharmacol. 6: 6.
    • (2006) BMC Pharmacol , vol.6 , pp. 6
    • Han, D.D.1    Gu, H.H.2
  • 58
    • 0242576358 scopus 로고    scopus 로고
    • Monoamine transporters and psychostimulant drugs
    • Rothman, R.B. & M.H. Baumann. 2003. Monoamine transporters and psychostimulant drugs. Eur. J. Pharmacol. 479: 23-40.
    • (2003) Eur. J. Pharmacol. , vol.479 , pp. 23-40
    • Rothman, R.B.1    Baumann, M.H.2
  • 61
    • 0031458637 scopus 로고    scopus 로고
    • Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action
    • Fon, E.A. et al. 1997. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19: 1271-1283.
    • (1997) Neuron , vol.19 , pp. 1271-1283
    • Fon, E.A.1
  • 62
    • 0034934620 scopus 로고    scopus 로고
    • Micewith very lowexpression of the vesicularmonoamine transporter 2 gene survive into adulthood: Potential mousemodel for parkinsonism
    • Mooslehner,K.A. et al. 2001.Micewith very lowexpression of the vesicularmonoamine transporter 2 gene survive into adulthood: potential mousemodel for parkinsonism. Mol. Cell. Biol. 21: 5321-5331.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5321-5331
    • Mooslehner, K.A.1
  • 63
    • 0032584230 scopus 로고    scopus 로고
    • Profound neuronal plasticity in response to inactivation of the dopamine transporter
    • Jones, S.R. et al. 1998. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc. Natl. Acad. Sci. USA 95: 4029-4034.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4029-4034
    • Jones, S.R.1
  • 64
    • 2442711509 scopus 로고    scopus 로고
    • Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine
    • Budygin, E.A. et al. 2004. Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine. Proc. Natl. Acad. Sci. USA 101: 7781-7786.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7781-7786
    • Budygin, E.A.1
  • 65
    • 0033360080 scopus 로고    scopus 로고
    • Loss of autoreceptor functions in mice lacking the dopamine transporter
    • Jones, S.R. et al. 1999. Loss of autoreceptor functions in mice lacking the dopamine transporter. Nat. Neurosci. 2: 649-655.
    • (1999) Nat. Neurosci. , vol.2 , pp. 649-655
    • Jones, S.R.1
  • 66
    • 0034193379 scopus 로고    scopus 로고
    • Dual effects of D-amphetamine on dopamine neurons mediated by dopamine and nondopamine receptors
    • Shi, W.X. et al. 2000. Dual effects of D-amphetamine on dopamine neurons mediated by dopamine and nondopamine receptors. J. Neurosci. 20: 3504-3511.
    • (2000) J. Neurosci , vol.20 , pp. 3504-3511
    • Shi, W.X.1
  • 67
    • 0036135209 scopus 로고    scopus 로고
    • Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter
    • Spielewoy, C. et al. 2001. Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter. Psychopharmacology (Berl) 159: 2-9.
    • (2001) Psychopharmacology (Berl) , vol.159 , pp. 2-9
    • Spielewoy, C.1
  • 68
    • 33751178666 scopus 로고    scopus 로고
    • Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice
    • Beaulieu, J.M. et al. 2006. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. J. Biol. Chem. 281: 32072-32080.
    • (2006) J. Biol. Chem. , vol.281 , pp. 32072-32080
    • Beaulieu, J.M.1
  • 69
    • 41949113570 scopus 로고    scopus 로고
    • Increased amphetamineinduced hyperactivity and reward in mice overexpressing the dopamine transporter
    • Salahpour, A. et al. 2008. Increased amphetamineinduced hyperactivity and reward in mice overexpressing the dopamine transporter.Proc.Natl.Acad. Sci.USA 105: 4405-4410.
    • (2008) Proc.Natl.Acad. Sci.USA , vol.105 , pp. 4405-4410
    • Salahpour, A.1
  • 70
    • 34250221173 scopus 로고    scopus 로고
    • Methamphetamine-induced locomotor activity and sensitization indopamine transporter and vesicular monoamine transporter 2 double mutant mice
    • Fukushima, S. et al. 2007. Methamphetamine-induced locomotor activity and sensitization indopamine transporter and vesicular monoamine transporter 2 double mutant mice. Psychopharmacology (Berl) 193: 55-62.
    • (2007) Psychopharmacology (Berl) , vol.193 , pp. 55-62
    • Fukushima, S.1
  • 71
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4- methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice
    • Bengel, D. et al. 1998. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4- methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Mol. Pharmacol. 53: 649-655.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 649-655
    • Bengel, D.1
  • 72
    • 0034882387 scopus 로고    scopus 로고
    • Methamphetamine neurotoxicity: Necrotic and apoptoticmechanisms and relevance to human abuse and treatment
    • Davidson,C. et al. 2001.Methamphetamine neurotoxicity: necrotic and apoptoticmechanisms and relevance to human abuse and treatment. Brain Res. Brain Res. Rev. 36: 1-22.
    • (2001) Brain Res. Brain Res. Rev , vol.36 , pp. 1-22
    • Davidson, C.1
  • 73
    • 15244348162 scopus 로고    scopus 로고
    • Interactions of dopamineD1 and D2 receptor antagonists with D-methamphetamine-induced hyperthermia and striatal dopamine and serotonin reductions
    • Broening,H.W., L.L.Morford&C.V.Vorhees. 2005. Interactions of dopamineD1 and D2 receptor antagonists with D-methamphetamine-induced hyperthermia and striatal dopamine and serotonin reductions. Synapse 56: 84-93.
    • (2005) Synapse , vol.56 , pp. 84-93
    • Broening, H.W.1    Morford, L.L.2    Vorhees, C.V.3
  • 74
    • 0029028776 scopus 로고
    • Effects of sulpiride and SCH 23390 on methamphetamineinduced changes in body temperature and lethality
    • Bronstein, D.M. & J.S. Hong. 1995. Effects of sulpiride and SCH 23390 on methamphetamineinduced changes in body temperature and lethality. J. Pharmacol. Exp. Ther. 274: 943-950.
    • (1995) J. Pharmacol. Exp. Ther , vol.274 , pp. 943-950
    • Bronstein, D.M.1    Hong, J.S.2
  • 75
    • 0041466261 scopus 로고    scopus 로고
    • The pharmacology and clinical pharmacology of 3,4- methylenedioxymethamphetamine (MDMA, "ecstasy")
    • Green, A.R. et al. 2003. The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol. Rev. 55: 463-508.
    • (2003) Pharmacol. Rev. , vol.55 , pp. 463-508
    • Green, A.R.1
  • 76
    • 34548709750 scopus 로고    scopus 로고
    • Methamphetamine-induced hyperthermia and lethal toxicity: Role of the dopamine and serotonin transporters
    • Numachi, Y. et al. 2007. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Eur. J. Pharmacol. 572: 120-128.
    • (2007) Eur. J. Pharmacol. , vol.572 , pp. 120-128
    • Numachi, Y.1
  • 77
    • 0018881202 scopus 로고
    • Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine
    • Wagner, G.C. et al. 1980. Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine. Brain Res. 181: 151-160.
    • (1980) Brain Res , vol.181 , pp. 151-160
    • Wagner, G.C.1
  • 78
    • 0018824851 scopus 로고
    • Longterm effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: A regional study
    • Ricaurte,G.A., C.R. Schuster&L.S. Seiden. 1980. Longterm effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: a regional study. Brain Res. 193: 153-163.
    • (1980) Brain Res , vol.193 , pp. 153-163
    • Ricaurte, G.A.1    Schuster, C.R.2    Seiden, L.S.3
  • 79
    • 0032125186 scopus 로고    scopus 로고
    • Role of dopamine transporter in methamphetamine-induced neurotoxicity: Evidence frommice lacking the transporter
    • Fumagalli, F. et al. 1998. Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence frommice lacking the transporter. J.Neurosci. 18: 4861-4869.
    • (1998) J.Neurosci , vol.18 , pp. 4861-4869
    • Fumagalli, F.1
  • 80
    • 0033118563 scopus 로고    scopus 로고
    • Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice
    • Fumagalli, F. et al. 1999. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. J. Neurosci. 19: 2424-2431.
    • (1999) J. Neurosci , vol.19 , pp. 2424-2431
    • Fumagalli, F.1
  • 81
    • 49549112268 scopus 로고    scopus 로고
    • Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis
    • Guillot, T.S. et al. 2008. Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis. J. Neurochem. 106: 2205-2217.
    • (2008) J. Neurochem. , vol.106 , pp. 2205-2217
    • Guillot, T.S.1
  • 82
    • 0031959343 scopus 로고    scopus 로고
    • Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice
    • Gainetdinov, R.R. et al. 1998. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. J. Neurochem. 70: 1973-1978.
    • (1998) J. Neurochem. , vol.70 , pp. 1973-1978
    • Gainetdinov, R.R.1
  • 83
    • 27644484010 scopus 로고    scopus 로고
    • Increased vulnerability to L-DOPA toxicity in dopaminergic neurons from VMAT2 heterozygote knockout mice
    • Kariya, S. et al. 2005. Increased vulnerability to L-DOPA toxicity in dopaminergic neurons from VMAT2 heterozygote knockout mice. J. Mol. Neurosci. 27: 277-279.
    • (2005) J. Mol. Neurosci. , vol.27 , pp. 277-279
    • Kariya, S.1
  • 84
    • 0036777534 scopus 로고    scopus 로고
    • L-DOPA does not cause neurotoxicity inVMAT2 heterozygote knockout mice
    • Reveron, M.E. et al. 2002. L-DOPA does not cause neurotoxicity inVMAT2 heterozygote knockout mice. Neurotoxicology 23: 611-619.
    • (2002) Neurotoxicology , vol.23 , pp. 611-619
    • Reveron, M.E.1
  • 85
    • 0026713852 scopus 로고
    • A CDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
    • Liu, Y. et al. 1992. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell 70: 539-551.
    • (1992) Cell , vol.70 , pp. 539-551
    • Liu, Y.1
  • 86
    • 0037109770 scopus 로고    scopus 로고
    • Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis
    • Larsen, K.E. et al. 2002. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J. Neurosci. 22: 8951-8960.
    • (2002) J. Neurosci. , vol.22 , pp. 8951-8960
    • Larsen, K.E.1
  • 87
    • 0036121286 scopus 로고    scopus 로고
    • Serotonin releasing agents.Neurochemical, therapeutic and adverse effects
    • Rothman, R.B. & M.H. Baumann. 2002. Serotonin releasing agents.Neurochemical, therapeutic and adverse effects. Pharmacol. Biochem. Behav. 71: 825-836.
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , pp. 825-836
    • Rothman, R.B.1    Baumann, M.H.2
  • 88
    • 0033941158 scopus 로고    scopus 로고
    • Human pharmacology of 3,4- methylenedioxymethamphetamine ("ecstasy"): Psychomotor performance and subjective effects
    • Cami, J. et al. 2000. Human pharmacology of 3,4- methylenedioxymethamphetamine ("ecstasy"): psychomotor performance and subjective effects. J. Clin. Psychopharmacol. 20: 455-466.
    • (2000) J. Clin. Psychopharmacol , vol.20 , pp. 455-466
    • Cami, J.1
  • 89
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman, R.B. et al. 2001. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39: 32-41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1
  • 90
    • 0031972749 scopus 로고    scopus 로고
    • CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine and MDMA conditioned place preferences
    • Bilsky, E.J. et al. 1998. CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine andMDMA conditioned place preferences. Pharmacol. Biochem. Behav. 59: 215-220.
    • (1998) Pharmacol. Biochem. Behav. , vol.59 , pp. 215-220
    • Bilsky, E.J.1
  • 91
    • 1942519843 scopus 로고    scopus 로고
    • Effect of SCH 23390 on (+/?)-3,4-methylenedioxymethamphetamine hyperactivity and self-administration in rats
    • Daniela, E. et al. 2004. Effect of SCH 23390 on (+/?)-3,4- methylenedioxymethamphetamine hyperactivity and self-administration in rats. Pharmacol. Biochem. Behav. 77: 745-750.
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 745-750
    • Daniela, E.1
  • 92
    • 0023109989 scopus 로고
    • In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain
    • Schmidt, C.J., J.A. Levin & W. Lovenberg. 1987. In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain. Biochem. Pharmacol. 36: 747-755.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 747-755
    • Schmidt, C.J.1    Levin, J.A.2    Lovenberg, W.3
  • 93
    • 34548149262 scopus 로고    scopus 로고
    • 3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice
    • Trigo, J.M. et al. 2007. 3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice. Biol. Psychiatry 62: 669-679.
    • (2007) Biol. Psychiatry. , vol.62 , pp. 669-679
    • Trigo, J.M.1
  • 94
    • 0034234502 scopus 로고    scopus 로고
    • Homeostatic regulation of serotonergic function by the serotonin transporter as revealed by nonviral gene transfer
    • Fabre,V. et al. 2000.Homeostatic regulation of serotonergic function by the serotonin transporter as revealed by nonviral gene transfer. J. Neurosci. 20: 5065-5075.
    • (2000) J. Eurosci. , vol.20 , pp. 5065-5075
    • Fabre, V.1
  • 95
    • 10344221595 scopus 로고    scopus 로고
    • Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression
    • Mathews, T.A. et al. 2004. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. J. Neurosci. Methods 140: 169-181.
    • (2004) J. Neurosci. Methods , vol.140 , pp. 169-181
    • Mathews, T.A.1
  • 96
    • 55549117850 scopus 로고    scopus 로고
    • Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild type mice
    • Renoir, T. et al. 2008. Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wildtype mice. Int. J. Neuropsychopharmacol. 11: 1149-1162.
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , pp. 1149-1162
    • Renoir, T.1
  • 97
    • 33751230490 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: A reappraisal of past and present findings
    • Baumann, M.H., X. Wang & R.B. Rothman. 2007. 3,4- Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings. Psychopharmacology (Berl) 189: 407-424.
    • (2007) Psychopharmacology (Berl) , Issue.189 , pp. 407-424
    • Baumann, M.H.1    Wang, X.2    Rothman, R.B.3
  • 98
    • 0035283681 scopus 로고    scopus 로고
    • Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice
    • Fornai, F. et al. 2001. Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice. Synapse 39: 213-221.
    • (2001) Synapse , vol.39 , pp. 213-221
    • Fornai, F.1
  • 99
    • 0029875120 scopus 로고    scopus 로고
    • Affinities of methylphenidate derivatives for dopamine, norepinephrine and serotonin transporters
    • Gatley, S.J. et al. 1996. Affinities of methylphenidate derivatives for dopamine, norepinephrine and serotonin transporters. Life Sci. 58: 231-239.
    • (1996) Life Sci , vol.58 , pp. 231-239
    • Gatley, S.J.1
  • 100
    • 0242500285 scopus 로고    scopus 로고
    • Differential psychostimulantinduced activation of neural circuits in dopamine transporter knockout and wild type mice
    • Trinh, J.V. et al. 2003. Differential psychostimulantinduced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience 118: 297-310.
    • (2003) Neuroscience , vol.118 , pp. 297-310
    • Trinh, J.V.1
  • 101
    • 54349123839 scopus 로고    scopus 로고
    • The effects of methylphenidate on knockin mice with a methylphenidate-resistant dopamine transporter
    • Tilley, M.R. & H.H. Gu. 2008. The effects of methylphenidate on knockin mice with a methylphenidate-resistant dopamine transporter. J. Pharmacol. Exp. Ther. 327: 554-560.
    • (2008) J. Pharmacol. Exp. Ther. , vol.327 , pp. 554-560
    • Tilley, M.R.1    Gu, H.H.2
  • 102
    • 58549083337 scopus 로고    scopus 로고
    • Functional mutations inmouse norepinephrine transporter reduce sensitivity to cocaine inhibition
    • Wei, H., E.R. Hill & H.H. Gu. 2009. Functional mutations inmouse norepinephrine transporter reduce sensitivity to cocaine inhibition. Neuropharmacology 56: 399-404.
    • (2009) Neuropharmacology , vol.56 , pp. 399-404
    • Wei, H.1    Hill, E.R.2    Gu, H.H.3
  • 103
    • 6844250767 scopus 로고    scopus 로고
    • Dopamine receptors: From structure to function
    • Missale,C. et al. 1998.Dopamine receptors: fromstructure to function. Physiol. Rev. 78: 189-225.
    • (1998) Physiol. Rev , vol.78 , pp. 189-225
    • Missale, C.1
  • 104
    • 0028307196 scopus 로고
    • Dopamine receptor distribution in the rat CNS: Elucidation using anti-peptide anti sera directed against D1A and D3 subtypes
    • Ariano, M.A. & D.R. Sibley. 1994. Dopamine receptor distribution in the rat CNS: elucidation using anti-peptide antisera directed against D1A and D3 subtypes. Brain Res. 649: 95-110.
    • (1994) Brain Res , vol.649 , pp. 95-110
    • Ariano, M.A.1    Sibley, D.R.2
  • 105
    • 0024741699 scopus 로고
    • Distribution of D2 dopamine recaptorm RNA in rat brain
    • Meador-Woodruff, J.H. et al. 1989. Distribution of D2 dopamine receptormRNAin rat brain. Proc.Natl.Acad. Sci. USA 86: 7625-7628.
    • (1989) Proc.Natl.Acad. Sci. USA , vol.86 , pp. 7625-7628
    • Meador-Woodruff, J.H.1
  • 106
    • 0026810530 scopus 로고
    • Localization and function of the D3 dopamine receptor
    • Sokoloff, P. et al. 1992. Localization and function of the D3 dopamine receptor. Arzneimittelforschung 42: 224-230.
    • (1992) Arzneimittelforschung , vol.42 , pp. 224-230
    • Sokoloff, P.1
  • 107
    • 0031128072 scopus 로고    scopus 로고
    • Distribution of D4 dopamine receptor in rat brain with sequence-specific antibodies
    • Defagot, M.C. et al. 1997. Distribution of D4 dopamine receptor in rat brain with sequence-specific antibodies. Brain Res. Mol. Brain Res. 45: 1-12.
    • (1997) Brain Res. Mol. Brain Res. , vol.45 , pp. 1-12
    • Defagot, M.C.1
  • 108
    • 0033933871 scopus 로고    scopus 로고
    • Dopamine D(5) receptor immunolocalization in rat and monkey brain
    • Ciliax, B.J. et al. 2000. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse 37: 125-145.
    • (2000) Synapse , vol.37 , pp. 125-145
    • Ciliax, B.J.1
  • 109
    • 0032872527 scopus 로고    scopus 로고
    • Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine
    • Caine, S.B. et al. 1999. Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine. J. Pharmacol. Exp. Ther. 291: 353-360.
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 353-360
    • Caine, S.B.1
  • 110
    • 0034124221 scopus 로고    scopus 로고
    • Dissociation of cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434
    • Platt, D.M., J.K. Rowlett & R.D. Spealman. 2000. Dissociation of cocaine-antagonist properties andmotoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434. J. Pharmacol. Exp. Ther. 293: 1017-1026.
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 1017-1026
    • Platt, D.M.1    Rowlett, J.K.2    Spealman, R.D.3
  • 111
    • 0029622329 scopus 로고
    • Retained cocaine conditioned place preference inD1 receptor deficientmice
    • Miner, L.L. et al. 1995. Retained cocaine conditioned place preference inD1 receptor deficientmice.Neuroreport 6: 2314-2316.
    • (1995) Neuroreport , vol.6 , pp. 2314-2316
    • Miner, L.L.1
  • 112
    • 0032563002 scopus 로고    scopus 로고
    • Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior
    • El-Ghundi, M. et al. 1998. Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. Eur. J. Pharmacol. 353: 149-158.
    • (1998) Eur. J. Pharmacol. , vol.353 , pp. 149-158
    • El-Ghundi, M.1
  • 113
    • 0033985297 scopus 로고    scopus 로고
    • Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor
    • Xu, M. et al. 2000. Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor. Brain Res. 852: 198-207.
    • (2000) Brain Res , vol.852 , pp. 198-207
    • Xu, M.1
  • 114
    • 49749148420 scopus 로고    scopus 로고
    • Comparison of dopamine D1andD5 receptor knockout mice for cocaine locomotor sensitization
    • Karlsson, R.M. et al. 2008. Comparison of dopamine D1andD5 receptor knockout mice for cocaine locomotor sensitization. Psychopharmacology (Berl) 200: 117-127.
    • (2008) Psychopharmacology (Berl) , vol.200 , pp. 117-127
    • Karlsson, R.M.1
  • 115
    • 0028605680 scopus 로고
    • Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice
    • Xu, M. et al. 1994. Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell 79: 945-955.
    • (1994) Cell , vol.79 , pp. 945-955
    • Xu, M.1
  • 116
    • 26944489214 scopus 로고    scopus 로고
    • Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation
    • Karasinska, J.M. et al. 2005. Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation. Eur. J. Neurosci. 22: 1741-1750.
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 1741-1750
    • Karasinska, J.M.1
  • 117
    • 36849040558 scopus 로고    scopus 로고
    • Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice
    • Caine, S.B. et al. 2007. Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice. J. Neurosci. 27: 13140-13150.
    • (2007) J. Neurosci. , vol.27 , pp. 13140-13150
    • Caine, S.B.1
  • 118
    • 0030564958 scopus 로고    scopus 로고
    • D1 dopamine receptor-deficient mouse: Cocaine-induced regulation of immediate-early gene and substance P expression in the striatum
    • Drago, J. et al. 1996. D1 dopamine receptor-deficient mouse: cocaine-induced regulation of immediate-early gene and substance P expression in the striatum. Neuroscience 74: 813-823.
    • (1996) Neuroscience , vol.74 , pp. 813-823
    • Drago, J.1
  • 119
    • 0036547075 scopus 로고    scopus 로고
    • Role of dopamine D2-like receptors in cocaine self-administration: Studies with D2 receptor mutant mice and novel D2 receptor antagonists
    • Caine, S.B. et al. 2002. Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. J. Neurosci. 22: 2977-2988.
    • (2002) J. Neurosci. , vol.22 , pp. 2977-2988
    • Caine, S.B.1
  • 120
    • 34249844534 scopus 로고    scopus 로고
    • Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine
    • Welter, M. et al. 2007. Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine. Proc. Natl. Acad. Sci. USA 104: 6840-6845.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6840-6845
    • Welter, M.1
  • 121
    • 0036360519 scopus 로고    scopus 로고
    • Cocaine-inducedlocomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice
    • Chausmer,A.L. et al. 2002.Cocaine-inducedlocomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice. Psychopharmacology (Berl) 163: 54-61.
    • (2002) Psychopharmacology (Berl) , vol.163 , pp. 54-61
    • Chausmer, A.L.1
  • 122
    • 0032507729 scopus 로고    scopus 로고
    • Lack of autoreceptormediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice
    • L'Hirondel, M. et al. 1998. Lack of autoreceptormediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice. Brain Res. 792: 253-262.
    • (1998) Brain Res , vol.792 , pp. 253-262
    • L'Hirondel, M.1
  • 123
    • 0032589784 scopus 로고    scopus 로고
    • Dopamine D2 receptordeficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum
    • Dickinson, S.D. et al. 1999. Dopamine D2 receptordeficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum. J. Neurochem. 72: 148-156.
    • (1999) J. Neurochem. , vol.72 , pp. 148-156
    • Dickinson, S.D.1
  • 124
    • 0037092433 scopus 로고    scopus 로고
    • Changes in extra cellular dopamine induced by morphine and cocaine: Crucial control by D2 receptors
    • Rouge-Pont, F. et al. 2002. Changes in extracellular dopamine induced by morphine and cocaine: crucial control by D2 receptors. J. Neurosci. 22: 3293-3301.
    • (2002) J. Neurosci. , vol.22 , pp. 3293-3301
    • Rouge-Pont, F.1
  • 125
    • 0027194404 scopus 로고
    • Modulation of cocaine self-administration in the rat through D-3 dopamine receptors
    • Caine, S.B. & G.F. Koob. 1993. Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science 260: 1814-1816.
    • (1993) Science , vol.260 , pp. 1814-1816
    • Caine, S.B.1    Koob, G.F.2
  • 126
    • 0030780877 scopus 로고    scopus 로고
    • Dopamine D3 receptormutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors
    • Xu,M. et al. 1997. Dopamine D3 receptormutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors. Neuron 19: 837-848.
    • (1997) Neuron , vol.19 , pp. 837-848
    • Xu, M.1
  • 127
    • 0242659155 scopus 로고    scopus 로고
    • Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice
    • Katz, J.L. et al. 2003. Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice. Psychopharmacology (Berl) 170: 108-114.
    • (2003) Psychopharmacology (Berl) , vol.170 , pp. 108-114
    • Katz, J.L.1
  • 128
    • 0030955365 scopus 로고    scopus 로고
    • Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine
    • Rubinstein, M. et al. 1997. Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell 90: 991-1001.
    • (1997) Cell , vol.90 , pp. 991-1001
    • Rubinstein, M.1
  • 129
    • 0141519512 scopus 로고    scopus 로고
    • Locomotor and discriminative-stimulus effects of cocaine in dopamine D5 receptor knockout mice
    • Elliot, E.E., D.R. Sibley & J.L. Katz. 2003. Locomotor and discriminative-stimulus effects of cocaine in dopamine D5 receptor knockout mice. Psychopharmacology (Berl) 169: 161-168.
    • (2003) Psychopharmacology (Berl) , vol.169 , pp. 161-168
    • Elliot, E.E.1    Sibley, D.R.2    Katz, J.L.3
  • 130
    • 0034601402 scopus 로고    scopus 로고
    • Cocaine effects on gene regulation in the striatum and behavior: Increased sensitivity in D3 dopamine receptor-deficient mice
    • Carta, A.R., C.R. Gerfen & H. Steiner. 2000. Cocaine effects on gene regulation in the striatum and behavior: increased sensitivity in D3 dopamine receptor-deficient mice. Neuroreport 11: 2395-2399.
    • (2000) Neuroreport , vol.11 , pp. 2395-2399
    • Carta, A.R.1    Gerfen, C.R.2    Steiner, H.3
  • 131
    • 0036594628 scopus 로고    scopus 로고
    • Role of the dopamineD3 receptor in reactivity to cocaine-associated cues in mice
    • Le Foll, B. et al. 2002. Role of the dopamineD3 receptor in reactivity to cocaine-associated cues in mice. Eur. J. Neurosci. 15: 2016-2026.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 2016-2026
    • Le Foll, B.1
  • 132
    • 51749109072 scopus 로고    scopus 로고
    • Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice
    • Doherty, J.M. et al. 2008. Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology 33: 2648-2656.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2648-2656
    • Doherty, J.M.1
  • 133
    • 49949097407 scopus 로고    scopus 로고
    • The dopamine D3/D2 agonist (+)-PD-128, 907 [(R-(+)-trans-3,4a,10b- tetrahydro- 4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4 -oxazin- 9-ol)] protects against acute and cocaine-kindled seizures in mice: Further evidence for the involvement of D3 receptors
    • Witkin, J.M. et al. 2008. The dopamine D3/D2 agonist (+)-PD-128,907 [(R-(+)-trans-3,4a,10b-tetrahydro- 4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4 -oxazin- 9-ol)] protects against acute and cocaine-kindled seizures in mice: further evidence for the involvement of D3 receptors. J. Pharmacol. Exp. Ther. 326: 930-938.
    • (2008) J. Pharmacol. Exp. Ther , vol.326 , pp. 930-938
    • Witkin, J.M.1
  • 134
    • 0030852689 scopus 로고    scopus 로고
    • Effects of repeated amphetamine treatment on the locomotor activity of the dopamine D1A-deficient mouse
    • Crawford, C.A. et al. 1997. Effects of repeated amphetamine treatment on the locomotor activity of the dopamine D1A-deficient mouse. Neuroreport 8: 2523-2527.
    • (1997) Neuroreport , vol.8 , pp. 2523-2527
    • Crawford, C.A.1
  • 135
    • 26944454806 scopus 로고    scopus 로고
    • Importance of D(1) receptors for associative components of amphetamineinduced behavioral sensitization and conditioned activity: A study using D(1) receptor knockout mice
    • McDougall, S.A. et al. 2005. Importance of D(1) receptors for associative components of amphetamineinduced behavioral sensitization and conditioned activity: a study using D(1) receptor knockout mice. Psychopharmacology (Berl) 183: 20-30.
    • (2005) Psychopharmacology (Berl) , Issue.183 , pp. 20-30
    • McDougall, S.A.1
  • 136
    • 0036007951 scopus 로고    scopus 로고
    • Role of D1-like receptors in amphetamine-induced behavioral sensitization: A study using D1A receptor knockout mice
    • Karper, P.E. et al. 2002. Role of D1-like receptors in amphetamine-induced behavioral sensitization: a study using D1A receptor knockout mice. Psychopharmacology (Berl) 159: 407-414.
    • (2002) Psychopharmacology (Berl) , vol.159 , pp. 407-414
    • Karper, P.E.1
  • 137
    • 0033969336 scopus 로고    scopus 로고
    • Topographical evaluation of behavioural phenotype in a line of mice with targeted gene deletion of theD2 dopamine receptor
    • Clifford, J.J. et al. 2000. Topographical evaluation of behavioural phenotype in a line of mice with targeted gene deletion of theD2 dopamine receptor. Neuropharmacology 39: 382-390.
    • (2000) Neuropharmacology , vol.39 , pp. 382-390
    • Clifford, J.J.1
  • 138
    • 47249102922 scopus 로고    scopus 로고
    • Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice
    • Kelly, M.A. et al. 2008. Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes Brain Behav. 7: 568-577.
    • (2008) Genes Brain Behav , vol.7 , pp. 568-577
    • Kelly, M.A.1
  • 139
    • 3042707145 scopus 로고    scopus 로고
    • Dopamine D4 receptor-deficient mice, congenic on the C57BL/6J background, are hypersensitive to amphetamine
    • Kruzich, P.J., K.L. Suchland & D.K. Grandy. 2004. Dopamine D4 receptor-deficient mice, congenic on the C57BL/6J background, are hypersensitive to amphetamine. Synapse 53: 131-139.
    • (2004) Synapse , vol.53 , pp. 131-139
    • Kruzich, P.J.1    Suchland, K.L.2    Grandy, D.K.3
  • 140
    • 33747067121 scopus 로고    scopus 로고
    • Dose-response analysis of locomotor activity and stereotypy in dopamine D3 receptor mutant mice following acute amphetamine
    • McNamara, R.K. et al. 2006. Dose-response analysis of locomotor activity and stereotypy in dopamine D3 receptor mutant mice following acute amphetamine. Synapse 60: 399-405.
    • (2006) Synapse , vol.60 , pp. 399-405
    • McNamara, R.K.1
  • 141
    • 67349123395 scopus 로고    scopus 로고
    • Differential susceptibility to ethanol and amphetamine sensitization in dopamine D3 receptor-deficient mice
    • Harrison, S.J. & J.N. Nobrega. 2009. Differential susceptibility to ethanol and amphetamine sensitization in dopamine D3 receptor-deficient mice. Psychopharmacology (Berl) 204: 49-59.
    • (2009) Psychopharmacology (Berl) , vol.204 , pp. 49-59
    • Harrison, S.J.1    Nobrega, J.N.2
  • 142
    • 0033137356 scopus 로고    scopus 로고
    • The dopamineD2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice
    • Ralph, R.J. et al. 1999. The dopamineD2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. J. Neurosci. 19: 4627-4633.
    • (1999) J. Neurosci , vol.19 , pp. 4627-4633
    • Ralph, R.J.1
  • 143
    • 12244262773 scopus 로고    scopus 로고
    • Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice
    • Xu, R. et al. 2002. Dopamine D2S and D2L receptors may differentially contribute to the actions of antipsychotic and psychotic agents in mice. Mol. Psychiatry 7: 1075-1082.
    • (2002) Mol. Psychiatry. , vol.7 , pp. 1075-1082
    • Xu, R.1
  • 144
    • 44349177395 scopus 로고    scopus 로고
    • Hyperthermic and lethal effects of methamphetamine: Roles of dopamine D1 and D2 receptors
    • Ito, M. et al. 2008. Hyperthermic and lethal effects of methamphetamine: roles of dopamine D1 and D2 receptors. Neurosci. Lett. 438: 327-329.
    • (2008) Neurosci. Lett. , vol.438 , pp. 327-329
    • Ito, M.1
  • 145
    • 33750222726 scopus 로고    scopus 로고
    • Differential contributions of dopamine D1, D2, and D3 receptors to MDMA induced effects on locomotor behavior patterns in mice
    • Risbrough, V.B. et al. 2006. Differential contributions of dopamine D1, D2, and D3 receptors to MDMAinduced effects on locomotor behavior patterns in mice. Neuropsychopharmacology 31: 2349-2358.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2349-2358
    • Risbrough, V.B.1
  • 146
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5- HT receptors and their function
    • Barnes, N.M. & T. Sharp. 1999. A review of central 5- HT receptors and their function. Neuropharmacology 38: 1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 148
    • 0035978018 scopus 로고    scopus 로고
    • Distribution of 5-ht(5A), 5- ht(5B), 5-ht(6) and 5-HT(7) receptor mRNAs in the rat brain
    • Kinsey, A.M. et al. 2001. Distribution of 5-ht(5A), 5- ht(5B), 5-ht(6) and 5-HT(7) receptor mRNAs in the rat brain. Brain Res. Mol. Brain Res. 88: 194-198.
    • (2001) Brain Res. Mol. Brain Res. , Issue.88 , pp. 194-198
    • Kinsey, A.M.1
  • 149
    • 0029827607 scopus 로고    scopus 로고
    • 5-HT receptors in mammalian brain: Receptor autoradiography and in situ hybridization studies of new ligands and newly identified receptors
    • Mengod, G. et al. 1996. 5-HT receptors in mammalian brain: receptor autoradiography and in situ hybridization studies of new ligands and newly identified receptors. Histochem. J. 28: 747-758.
    • (1996) Histochem. J. , vol.28 , pp. 747-758
    • Mengod, G.1
  • 150
    • 31844438317 scopus 로고    scopus 로고
    • Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine
    • Muller, C.P. & J.P. Huston. 2006. Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine. Trends Pharmacol. Sci. 27: 105-112.
    • (2006) Trends Pharmacol. Sci , vol.27 , pp. 105-112
    • Muller, C.P.1    Huston, J.P.2
  • 151
    • 0032222416 scopus 로고    scopus 로고
    • Serotonin1B receptor stimulation enhances cocaine reinforcement
    • Parsons, L.H., F.Weiss & G.F. Koob. 1998. Serotonin1B receptor stimulation enhances cocaine reinforcement. J. Neurosci. 18: 10078-10089.
    • (1998) J. Neurosci. , vol.18 , pp. 10078-10089
    • Parsons, L.H.1    Weiss, F.2    Koob, G.F.3
  • 152
    • 0033560989 scopus 로고    scopus 로고
    • RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaineinduced increases in nucleus accumbens dopamine
    • Parsons, L.H., G.F. Koob & F. Weiss. 1999. RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaineinduced increases in nucleus accumbens dopamine. Synapse 32: 132-135.
    • (1999) Synapse , vol.32 , pp. 132-135
    • Parsons, L.H.1    Koob, G.F.2    Weiss, F.3
  • 153
    • 0034493851 scopus 로고    scopus 로고
    • Modulation of the effects of cocaine by 5-HT1B receptors: A comparison of knockouts and antagonists
    • Castanon, N. et al. 2000. Modulation of the effects of cocaine by 5-HT1B receptors: a comparison of knockouts and antagonists. Pharmacol. Biochem. Behav. 67: 559-566.
    • (2000) Pharmacol. Biochem. Behav. , vol.67 , pp. 559-566
    • Castanon, N.1
  • 154
    • 0030814702 scopus 로고    scopus 로고
    • Intravenous cocaine selfadministration in mice lacking 5-HT1B receptors
    • Rocha, B.A. et al. 1997. Intravenous cocaine selfadministration in mice lacking 5-HT1B receptors. Pharmacol. Biochem. Behav. 57: 407-412.
    • (1997) Pharmacol. Biochem. Behav. , vol.57 , pp. 407-412
    • Rocha, B.A.1
  • 155
    • 0034126292 scopus 로고    scopus 로고
    • Absence of cocaine-induced place conditioning in serotonin 1B receptor knock-out mice
    • Belzung, C. et al. 2000. Absence of cocaine-induced place conditioning in serotonin 1B receptor knock-out mice. Pharmacol. Biochem. Behav. 66: 221-225.
    • (2000) Pharmacol. Biochem. Behav. , vol.66 , pp. 221-225
    • Belzung, C.1
  • 156
    • 0034120050 scopus 로고    scopus 로고
    • Regionspecific enhancement of basal extra cellular and cocaine-evoked dopamine levels following constitutive deletion of the Serotonin(1B) receptor
    • Shippenberg, T.S., R. Hen & M. He. 2000. Regionspecific enhancement of basal extracellular and cocaine-evoked dopamine levels following constitutive deletion of the Serotonin(1B) receptor. J. Neurochem. 75: 258-265.
    • (2000) J. Neurochem. , Issue.75 , pp. 258-265
    • Shippenberg, T.S.1    Hen, R.2    He, M.3
  • 157
    • 0030609867 scopus 로고    scopus 로고
    • 5- Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: Converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935
    • Lucas, J.J., L. Segu & R. Hen. 1997. 5- Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935. Mol. Pharmacol. 51: 755-763.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 755-763
    • Lucas, J.J.1    Segu, L.2    Hen, R.3
  • 158
    • 33846426067 scopus 로고    scopus 로고
    • Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission
    • Alex, K.D. & E.A. Pehek. 2007. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol. Ther. 113: 296-320.
    • (2007) Pharmacol. Ther. , vol.113 , pp. 296-320
    • Alex, K.D.1    Pehek, E.A.2
  • 159
    • 0037111849 scopus 로고    scopus 로고
    • Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptormutant mice
    • Rocha, B.A. et al. 2002. Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptormutant mice. J.Neurosci. 22: 10039-10045.
    • (2002) J.Neurosci. , vol.22 , pp. 10039-10045
    • Rocha, B.A.1
  • 160
    • 34548008147 scopus 로고    scopus 로고
    • Paradoxical constitutive behavioral sensitization to amphetamine in mice lacking 5-HT2A receptors
    • Salomon, L. et al. 2007. Paradoxical constitutive behavioral sensitization to amphetamine in mice lacking 5-HT2A receptors. Psychopharmacology (Berl) 194: 11-20.
    • (2007) Psychopharmacology (Berl) , vol.194 , pp. 11-20
    • Salomon, L.1
  • 161
    • 0034789503 scopus 로고    scopus 로고
    • Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor
    • Allan, A.M. et al. 2001. Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor. Psychopharmacology (Berl) 158: 18-27.
    • (2001) Psychopharmacology (Berl) , Issue.158 , pp. 18-27
    • Allan, A.M.1
  • 162
    • 34249799004 scopus 로고    scopus 로고
    • Constitutive deletion of the serotonin-7 (5-HT(7)) receptor decreases electrical and chemical seizure thresholds
    • Witkin, J.M. et al. 2007. Constitutive deletion of the serotonin-7 (5-HT(7)) receptor decreases electrical and chemical seizure thresholds. Epilepsy Res. 75: 39-45.
    • (2007) Epilepsy Res , vol.75 , pp. 39-45
    • Witkin, J.M.1
  • 163
    • 0035216761 scopus 로고    scopus 로고
    • Amphetamine-induced locomotor activation in 5-HT(1B) knockout mice: Effects of injection route on acute and sensitized responses
    • Bronsert, M.R. et al. 2001. Amphetamine-induced locomotor activation in 5-HT(1B) knockout mice: effects of injection route on acute and sensitized responses. Behav. Pharmacol. 12: 549-555.
    • (2001) Behav. Pharmacol , vol.12 , pp. 549-555
    • Bronsert, M.R.1
  • 164
    • 0032534296 scopus 로고    scopus 로고
    • 5-HT1B receptor modulation of prepulse inhibition: Recent findings in wild-type and 5-HT1B knockout mice
    • Dulawa, S.C. et al. 1998. 5-HT1B receptor modulation of prepulse inhibition: recent findings in wild-type and 5-HT1B knockout mice. Ann. N. Y. Acad. Sci. 861: 79-84.
    • (1998) Ann. N. Y. Acad. Sci. , vol.861 , pp. 79-84
    • Dulawa, S.C.1
  • 165
    • 0034073387 scopus 로고    scopus 로고
    • Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice
    • Dulawa, S.C. et al. 2000. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology (Berl) 149: 306-312.
    • (2000) Psychopharmacology (Berl) , vol.149 , pp. 306-312
    • Dulawa, S.C.1
  • 166
    • 0032898984 scopus 로고    scopus 로고
    • Loco motor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor
    • Scearce-Levie, K., S.S.Viswanathan&R.Hen. 1999. Locomotor response toMDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology (Berl) 141: 154-161.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 154-161
    • Scearce-Levie, K.1    Viswanathan, S.S.2    Hen, R.3
  • 167
    • 4043141566 scopus 로고    scopus 로고
    • The somatodendritic release of dopamine in the ventral tegmental area and its regulation by afferent transmitter systems
    • Adell, A. & F. Artigas. 2004. The somatodendritic release of dopamine in the ventral tegmental area and its regulation by afferent transmitter systems. Neurosci. Biobehav. Rev. 28: 415-431.
    • (2004) Neurosci. Biobehav. Rev. , vol.28 , pp. 415-431
    • Adell, A.1    Artigas, F.2
  • 168
    • 33748770069 scopus 로고    scopus 로고
    • Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine
    • Schank, J.R. et al. 2006. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology 31: 2221-2230.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2221-2230
    • Schank, J.R.1
  • 169
    • 33750978676 scopus 로고    scopus 로고
    • Noradrenaline is necessary for the hedonic properties of addictive drugs
    • Jasmin, L., M. Narasaiah & D. Tien. 2006. Noradrenaline is necessary for the hedonic properties of addictive drugs. Vascul. Pharmacol. 45: 243-250.
    • (2006) Vascul. Pharmacol. , Issue.45 , pp. 243-250
    • Jasmin, L.1    Narasaiah, M.2    Tien, D.3
  • 170
    • 0036550282 scopus 로고    scopus 로고
    • Alpha1b-adrenergic receptors control loco motor and rewarding effects of psychostimulants and opiates
    • Drouin, C. et al. 2002. Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates. J. Neurosci. 22: 2873-2884.
    • (2002) J. Neurosci. , vol.22 , pp. 2873-2884
    • Drouin, C.1
  • 171
    • 43049157802 scopus 로고    scopus 로고
    • Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety
    • Schank, J.R., L.C. Liles & D. Weinshenker. 2008. Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety. Biol. Psychiatry 63: 1007-1012.
    • (2008) Biol. Psychiatry. , vol.63 , pp. 1007-1012
    • Schank, J.R.1    Liles, L.C.2    Weinshenker, D.3
  • 172
    • 41949100080 scopus 로고    scopus 로고
    • Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaineinduced seizures
    • Gaval-Cruz, M. et al. 2008. Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaineinduced seizures. Pharmacol. Biochem. Behav. 89: 556-562.
    • (2008) Pharmacol. Biochem. Behav. , vol.89 , pp. 556-562
    • Gaval-Cruz, M.1
  • 173
    • 0037108974 scopus 로고    scopus 로고
    • Mice with chronic norepinephrine deficiency resemble amphetaminesensitized animals
    • Weinshenker, D. et al. 2002. Mice with chronic norepinephrine deficiency resemble amphetaminesensitized animals.Proc.Natl.Acad. Sci.USA99: 13873-13877.
    • (2002) Proc.Natl.Acad. Sci.USA , vol.99 , pp. 13873-13877
    • Weinshenker, D.1
  • 174
    • 19244370789 scopus 로고    scopus 로고
    • Stimulation of postsynaptic alpha1b- and alpha2-adrenergic receptors amplifies dopamine-mediated loco motor activity in both rats and mice
    • Villegier, A.S. et al. 2003. Stimulation of postsynaptic alpha1b- and alpha2-adrenergic receptors amplifies dopamine-mediated locomotor activity in both rats and mice. Synapse 50: 277-284.
    • (2003) Synapse , vol.50 , pp. 277-284
    • Villegier, A.S.1
  • 175
    • 0031862622 scopus 로고    scopus 로고
    • D-amphetamine and L- 5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the alpha2Cadrenergic receptor subtype
    • Sallinen, J. et al. 1998. D-amphetamine and L- 5-hydroxytryptophan- induced behaviours in mice with genetically-altered expression of the alpha2Cadrenergic receptor subtype. Neuroscience 86: 959-965.
    • (1998) Neuroscience , vol.86 , pp. 959-965
    • Sallinen, J.1
  • 176
    • 10844284619 scopus 로고    scopus 로고
    • 5-HT2A and alpha1b-adrenergic receptors entirelymediate dopamine release, loco motor response and behavioural sensitization to opiates and psychostimulants
    • Auclair, A. et al. 2004. 5-HT2A and alpha1b-adrenergic receptors entirelymediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants. Eur. J. Neurosci. 20: 3073-3084.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 3073-3084
    • Auclair, A.1
  • 177
    • 33646545347 scopus 로고    scopus 로고
    • Behavioral sensitization to amphetamine results from an uncoupling between noradrenergic and serotonergic neurons
    • Salomon, L. et al. 2006. Behavioral sensitization to amphetamine results from an uncoupling between noradrenergic and serotonergic neurons. Proc. Natl. Acad. Sci. USA 103: 7476-7481.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7476-7481
    • Salomon, L.1
  • 178
    • 2942689967 scopus 로고    scopus 로고
    • Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines
    • Lahdesmaki, J. et al. 2004. Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines. Neuropsychopharmacology 29: 1282-1293.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1282-1293
    • Lahdesmaki, J.1
  • 179
    • 30644457692 scopus 로고    scopus 로고
    • Role of alpha2Aadrenoceptors in the effects of MDMA on body temperature in the mouse
    • Bexis, S. & J.R. Docherty. 2005. Role of alpha2Aadrenoceptors in the effects of MDMA on body temperature in the mouse. Br. J. Pharmacol. 146: 1-6.
    • (2005) Br. J. Pharmacol. , vol.146 , pp. 1-6
    • Bexis, S.1    Docherty, J.R.2
  • 180
    • 41749120091 scopus 로고    scopus 로고
    • Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine
    • Weinshenker, D. et al. 2008. Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine. J. Neurochem. 105: 471-483.
    • (2008) J. Neurochem. , vol.105 , pp. 471-483
    • Weinshenker, D.1
  • 181
    • 59649122728 scopus 로고    scopus 로고
    • Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers
    • Drgon, T. et al. 2009. Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers. Mol. Med. 15: 21-27.
    • (2009) Mol. Med. , vol.15 , pp. 21-27
    • Drgon, T.1
  • 182
    • 33845465213 scopus 로고    scopus 로고
    • Pooled association genome scanning for alcohol dependence using 104,268 SNPS: Validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism
    • Johnson, C. et al. 2006. Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B: 844-853.
    • (2006) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.141 B , pp. 844-853
    • Johnson, C.1
  • 183
    • 59849090159 scopus 로고    scopus 로고
    • Genome wide association for substance dependence: Convergent results from epidemiologic and research volunteer samples
    • Johnson, C. et al. 2008. Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples. BMC Med. Genet. 9: 113.
    • (2008) BMC Med. Genet. , vol.9 , pp. 113
    • Johnson, C.1
  • 184
    • 33845434956 scopus 로고    scopus 로고
    • Addiction molecular genetics: 639,401 SNP whole genome association identifies many "cell adhesion" genes
    • Liu, Q.R. et al. 2006. Addiction molecular genetics: 639,401 SNPwhole genome association identifies many "cell adhesion" genes. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B: 918-925.
    • (2006) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.141 B , pp. 918-925
    • Liu, Q.R.1
  • 185
    • 54949105395 scopus 로고    scopus 로고
    • Molecular genetics of addiction and related heritable phenotypes: Genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects
    • Uhl, G.R. et al. 2008. Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects. Ann. N. Y. Acad. Sci. 1141: 318-381.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1141 , pp. 318-381
    • Uhl, G.R.1
  • 186
    • 68649085171 scopus 로고    scopus 로고
    • Addiction genetics and pleiotropic effects of commonhaplotypes thatmake polygenic contributions to vulnerability to substance dependence
    • Uhl, G.R. et al. 2009.Addiction genetics and pleiotropic effects of commonhaplotypes thatmake polygenic contributions to vulnerability to substance dependence. J. Neurogenet. 23: 272-282.
    • (2009) J. Neurogenet. , vol.23 , pp. 272-282
    • Uhl, G.R.1
  • 187
    • 40349091515 scopus 로고    scopus 로고
    • Genome-wide association for methamphetamine dependence: Convergent results from 2 samples
    • Uhl, G.R. et al. 2008. Genome-wide association for methamphetamine dependence: convergent results from 2 samples. Arch. Gen. Psychiatry 65: 345-355.
    • (2008) Arch. Gen. Psychiatry. , vol.65 , pp. 345-355
    • Uhl, G.R.1
  • 188
    • 36849069820 scopus 로고    scopus 로고
    • "Higher order" addiction molecular genetics: Convergent data from genome-wide association in humans and mice
    • Uhl, G.R. et al. 2008. "Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice. Biochem. Pharmacol. 75: 98-111.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 98-111
    • Uhl, G.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.