Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation

European Journal of Neuroscience

Volumn 22, Issue 7, 2005, Pages 1741-1750

  Karasinska, Joanna M ^a   George, Susan R ^a,b   Cheng, Regina ^a,b   O'Dowd, Brian F ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

Cocaine reward; Dopamine receptor; Gene knockout mice; Locomotor activity; Phosphorylated CREB

Indexed keywords

COCAINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 3 RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; HABITUATION; LOCOMOTION; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PUTAMEN; REARING; RECEPTOR UPREGULATION; REWARD;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CELL COUNT; COCAINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PHOSPHORYLATION; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D3; REWARD; TIME FACTORS;

EID: 26944489214     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04353.x     Document Type: Article

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