Methamphetamine-induced hyperthermia and lethal toxicity: Role of the dopamine and serotonin transporters

European Journal of Pharmacology

Volumn 572, Issue 2-3, 2007, Pages 120-128

  Numachi, Yohtaro ^a   Ohara, Arihisa ^a   Yamashita, Motoyasu ^a   Fukushima, Setsu ^a   Kobayashi, Hideaki ^a   Hata, Harumi ^a   Watanabe, Hidekazu ^a   Hall, F Scott ^b   Lesch, Klaus Peter ^c   Murphy, Dennis L ^d   Uhl, George R ^b   Sora, Ichiro ^a,b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Interleukin 1 ; Monoamine; Norepinephrine; Paradoxical hypothermia; Transgenic knockout mouse

Indexed keywords

DOPAMINE TRANSPORTER; FLUOXETINE; INTERLEUKIN 1BETA; MESSENGER RNA; METHAMPHETAMINE; NISOXETINE; PYROGEN; SEROTONIN TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HYPERTHERMIA; HYPOTHALAMUS; KNOCKOUT MOUSE; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; BODY TEMPERATURE; CENTRAL NERVOUS SYSTEM STIMULANTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; FEVER; FLUOXETINE; INTERLEUKIN-1BETA; LETHAL DOSE 50; MALE; METHAMPHETAMINE; MICE; MICE, KNOCKOUT; RNA, MESSENGER; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS;

EID: 34548709750     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.06.022     Document Type: Article

References (39)

1. Albers D.S., and Sonsalla P.K. Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents. J. Pharmacol. Exp. Ther. 275 (1995) 1104-1114
2. Ali S.F., Newport G.D., Holson R.R., Slikker Jr. W., and Bowyer J.F. Low environmental temperatures or pharmacologic agents that produce hypothermia decrease methamphetamine neurotoxicity in mice. Brain Res. 658 (1994) 33-38
3. Bengel D., Murphy D.L., Andrews A.M., Wichems C.H., Feltner D., Heils A., Mossner R., Westphal H., and Lesch K.P. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Mol. Pharmacol. 53 (1998) 649-655
4. Bowyer J.F., Davies D.L., Schmued L., Broening H.W., Newport G.D., Slikker Jr. W., and Holson R.R. Further studies of the role of hyperthermia in methamphetamine neurotoxicity. J. Pharmacol. Exp. Ther. 268 (1994) 1571-1580
5. Broening H.W., Morford L.L., and Vorhees C.V. Interactions of dopamine D1 and D2 receptor antagonists with d-methamphetamine-induced hyperthermia and striatal dopamine and serotonin reductions. Synapse 56 (2005) 84-93
6. Bronstein D.M., and Hong J.S. Effects of sulpiride and SCH 23390 on methamphetamine-induced changes in body temperature and lethality. J. Pharmacol. Exp. Ther. 274 (1995) 943-950
7. Canini F., and Bourdon L. Dopamine involvement in thermoregulatory responses to heat in rats. Neurosci. Lett. 241 (1998) 91-94
8. Chan T.C., Evans S.D., and Clark R.F. Drug-induced hyperthermia. Crit. Care Clin. 13 (1997) 785-808
9. Dascombe M.J., Rothwell N.J., Sagay B.O., and Stock M.J. Pyrogenic and thermogenic effects of interleukin 1 beta in the rat. Am. J. Physiol. 256 (1989) E7-E11
10. Davidson C., Gow A.J., Lee T.H., and Ellinwood E.H. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res. Brain Res. Rev. 36 (2001) 1-22
11. Davis W.M., Hatoum H.T., and Waters I.W. Interactions of catecholaminergic receptor blockers with lethal doses of amphetamine or substituted amphetamines in mice. Res. Commun. Chem. Pathol. Pharmacol. 21 (1978) 27-36
12. Derlet R.W., Albertson T.E., and Rice P. Antagonism of cocaine, amphetamine, and methamphetamine toxicity. Pharmacol. Biochem. Behav. 36 (1990) 745-749
13. Fumagalli F., Gainetdinov R.R., Valenzano K.J., and Caron M.G. Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. J. Neurosci. 18 (1998) 4861-4869
14. Funahashi M., Kohda H., Hori O., Hayashida H., and Kimura H. Potentiating effect of morphine upon d-methamphetamine-induced hyperthermia in mice. Effects of naloxone and haloperidol. Pharmacol. Biochem. Behav. 36 (1990) 345-350
15. Green A.R., Mechan A.O., Elliott J.M., O'Shea E., and Colado M.I. The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol. Rev. 55 (2003) 463-508
16. Hall F.S., Li X.F., Sora I., Xu F., Caron M., Lesch K.P., Murphy D.L., and Uhl G.R. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115 (2002) 153-161
17. Halladay A.K., Kusnecov A., Michna L., Kita T., Hara C., and Wagner G.C. Relationship between methamphetamine-induced dopamine release, hyperthermia, self-injurious behaviour and long term dopamine depletion in BALB/c and C57BL/6 mice. Pharmacol. Toxicol. 93 (2003) 33-41
18. Hanson G.R., Rau K.S., and Fleckenstein A.E. The methamphetamine experience: a NIDA partnership. Neuropharmacology 47 Suppl 1 (2004) 92-100
19. He J., Xu H., Yang Y., Zhang X., and Li X.M. Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats. Brain Res. 1018 (2004) 186-192
20. Imam S.Z., and Ali S.F. Aging increases the susceptibility to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia. J. Neurochem. 78 (2001) 952-959
21. Kita T., Wagner G.C., and Nakashima T. Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption. J. Pharmacol. Sci. 92 (2003) 178-195
22. Kuperman D.I., Freyaldenhoven T.E., Schmued L.C., and Ali S.F. Methamphetamine-induced hyperthermia in mice: examination of dopamine depletion and heat-shock protein induction. Brain Res. 771 (1997) 221-227
23. Leon L.R. Invited review: cytokine regulation of fever: studies using gene knockout mice. J. Appl. Physiol. 92 (2002) 2648-2655
24. Miller D.B., and O'Callaghan J.P. Elevated environmental temperature and methamphetamine neurotoxicity. Environ. Res. 92 (2003) 48-53
25. Murphy D.L., Uhl G.R., Holmes A., Ren-Patterson R., Hall F.S., Sora I., Detera-Wadleigh S., and Lesch K.P. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes Brain Behav. 2 (2003) 350-364
26. Nakajima A., Yamada K., Nagai T., Uchiyama T., Miyamoto Y., Mamiya T., He J., Nitta A., Mizuno M., Tran M.H., Seto A., Yoshimura M., Kitaichi K., Hasegawa T., Saito K., Yamada Y., Seishima M., Sekikawa K., Kim H.C., and Nabeshima T. Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity. J. Neurosci. 24 (2004) 2212-2225
27. Namiki M., Mori T., Sawaguchi T., Ito S., and Suzuki T. Underlying mechanism of combined effect of methamphetamine and morphine on lethality in mice and therapeutic potential of cooling. J. Pharmacol. Sci. 99 (2005) 168-176
28. Orjales A., Mosquera R., Toledo A., Pumar M.C., Garcia N., Cortizo L., Labeaga L., and Innerarity A. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters. J. Med. Chem. 46 (2003) 5512-5532
29. Owens M.J., Knight D.L., and Nemeroff C.B. Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine. Biol. Psychiatry 50 (2001) 345-350
30. Sato M., Numachi Y., and Hamamura T. Relapse of paranoid psychotic state in methamphetamine model of schizophrenia. Schizophr. Bull. 18 (1992) 115-122
31. Schobitz B., De Kloet E.R., and Holsboer F. Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog. Neurobiol. 44 (1994) 397-432
32. Seiden L.S., Sabol K.E., and Ricaurte G.A. Amphetamine: effects on catecholamine systems and behavior. Annu. Rev. Pharmacol. Toxicol. 33 (1993) 639-677
33. Shen H.W., Hagino Y., Kobayashi H., Shinohara-Tanaka K., Ikeda K., Yamamoto H., Yamamoto T., Lesch K.P., Murphy D.L., Hall F.S., Uhl G.R., and Sora I. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology 29 (2004) 1790-1799
34. Sora I., Hall F.S., Andrews A.M., Itokawa M., Li X.F., Wei H.B., Wichems C., Lesch K.P., Murphy D.L., and Uhl G.R. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 5300-5305
35. Sora I., Wichems C., Takahashi N., Li X.F., Zeng Z., Revay R., Lesch K.P., Murphy D.L., and Uhl G.R. Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 7699-7704
36. Tringali G., Dello Russo C., Preziosi P., and Navarra P. Hypothalamic interleukin-1 in physiology and pathology. Toxicol. Lett. 102-103 (1998) 295-299
37. Uchima E., Ogura Y., Hiraga Y., and Shikata I. Relationship between methamphetamine toxicity and catecholamine levels in heart and brain of mice. Nippon Hoigaku Zasshi 37 (1983) 198-208
38. Wagner G.C., Tekirian T.L., and Cheo C.T. Sexual differences in sensitivity to methamphetamine toxicity. J. Neural Transm. Gen. Sect. 93 (1993) 67-70
39. Yamaguchi T., Kuraishi Y., Minami M., Nakai S., Hirai Y., and Satoh M. Methamphetamine-induced expression of interleukin-1 beta mRNA in the rat hypothalamus. Neurosci. Lett. 128 (1991) 90-92