Serotonin(1B) receptor stimulation enhances cocaine reinforcement

Journal of Neuroscience

Volumn 18, Issue 23, 1998, Pages 10078-10089

  Parsons, Loren H ^a   Weiss, Friedbert ^a   Koob, George F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

5 HT(1A); 5 HT(1B); 8 OH DPAT; Cocaine; CP 93,129; CP 94,253; GR 127,935; PMPPI; Progressive ratio; RU 24969; Self administration

Indexed keywords

3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; 4 IODO N [2 [4 (METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N 2 PYRIDINYL BENZAMIDE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; 5 PROPOXY 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDINE; COCAINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1B AGONIST; SEROTONIN 1B RECEPTOR; UNCLASSIFIED DRUG; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 (1,2,5,6 TETRAHYDROPYRID 4 YL)PYRROLO(3,2 B)PYRID 5 ONE; 3-(1,2,5,6-TETRAHYDROPYRID-4-YL)PYRROLO(3,2-B)PYRID-5-ONE; 4 (2' METHOXYPHENYL) 1 (2' (N (2'' PYRIDINYL) 4 IODOBENZAMIDO)ETHYL)PIPERAZINE; 4-(2'-METHOXYPHENYL)-1-(2'-(N-(2''-PYRIDINYL)-4-IODOBENZAMIDO)ETHYL)PIPERAZINE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDINYL)1H INDOLE; 5-METHOXY 3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)1H INDOLE; AMINOPYRIDINE DERIVATIVE; DOPAMINE UPTAKE INHIBITOR; INDOLE DERIVATIVE; OXADIAZOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG SELF ADMINISTRATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SUBCUTANEOUS DRUG ADMINISTRATION; ANIMAL; COCAINE DEPENDENCE; PATHOPHYSIOLOGY; PHYSIOLOGY; WISTAR RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; AMINOPYRIDINES; ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; INJECTIONS, INTRAVENTRICULAR; MALE; OXADIAZOLES; PIPERAZINES; PYRIDINES; PYRROLES; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; SELF ADMINISTRATION; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0032222416     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-23-10078.1998     Document Type: Article

References (84)

1. Aronson SC, Black JE, McDougle CJ, Scanley BE, Jatlow P, Kosten TR, Heninger GR, Price LH (1995) Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl) 119:179-185.
2. 1A-mediated prolactin secretion in rats. Neurosci Lett 193:9-12.
3. 2 receptor stimulation in rats. Neuropharmacology 35:295-301.
4. 2/1C agonist DOI. Biol Psychiatry 34:576-577.
5. Bergman J, Kamien JB, Spealman RD (1990) Antagonism of cocaine self-administration by selective D1 and D2 antagonists. Behav Pharmacol 1:355-363.
6. Bhat RV, Baraban JM (1993) Activation of transcription factor genes in striatum by cocaine: role of both serotonin and dopamine systems. J Pharmacol Exp Ther 267:496-505.
7. Bhat RV, Cole AJ, Baraban JM (1992) Role of monoamine systems in activation of zif268 by cocaine. J Psychiatr Neurosci 17:94-102.
8. 1A agonist gepirone: electrophysiological studies in the rat brain. Synapse 1:470-480.
9. Boulenguez P, Rawlins JNP, Chauveau J, Joseph MH, Mitchell SN, Gray JA (1996) Modulation of dopamine release in the nucleus accumbens by 5-HT1B agonists: involvement of the hippocampo-accumbens pathway. Neuropharmacology 35:1521-1529.
10. 1B binding sites in rat brain. Naunyn Schmiedebergs Arch Pharmacol 347:569-582.
11. 1F receptor messenger RNA in rodent and primate brain. Neuropharmacology 33:367-386.
12. Buydens-Branchey L, Branchey M, Fergeson P, Hudson J, McKerin C (1997) Craving for cocaine in addicted users. Role of serotonergic mechanisms. Am J Addict 6:65-73.
13. Caine SB, Koob GF (1995) Pretreatment with the dopamine agonist 7-OH-DPAT shifts the cocaine self-administration dose-effect function to the left under different schedules in the rat. Behav Pharmacol 6:333-347.
14. Caine SB, Lintz R, Koob GF (1993) Intravenous drug self-administration techniques in animals. In: Behavioural neuroscience: a practical approach, Vol 2 (Sahgal A, ed), pp 116-143. Oxford: Oxford UP.
15. 2C receptors. J Pharmacol Exp Ther 274:1414-1424.
16. 1B receptor agonists. Neuropharmacology 36:373-381.
17. Callaway CW, Geyer MA (1992) Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1b agonist. J Pharmacol Exp Ther 263:318-326.
18. Cameron DL, Williams JT (1994) Cocaine inhibits GABA release in the VTA through endogenous 5-HT. J Neurosci 14:6763-6767.
19. Carroll ME, Lac ST, Asencio M, Kragh R (1990a) Fluoxetine reduces intravenous cocaine self-administration in rats. Pharmacol Biochem Behav 35:237-244.
20. Carroll ME, Lac ST, Asencio M, Kragh R (1990b) Intravenous cocaine self-administration is reduced by dietary L-tryptophan. Psychopharmacology (Berl) 100:293-300.
21. 1B receptor. Br J Pharmacol 110:1621-1629.
22. Chen NH, Reith MEA (1994) Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships. J Neurochem 63:1701-1713.
23. Chen NH, Reith MEA (1995) Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (±)-8-hydroxy-2-(di-n-propylamino)tetralin. J Neurochem 64:1585-1597.
24. Cunningham KA (1995) Modulation of serotonin function by acute and chronic cocaine: neurophysiological analyses. In: The neurobiology of cocaine: cellular and molecular mechanisms (Hammer Jr RP, ed), pp 288-321. Boca Raton, FL: CRC.
25. Cunningham KA, Paris JM, Goeders NE (1992) Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse 11:112-123.
26. Depoortere RY, Li DH, Lane JD, Emmett-Oglesby MW (1993) Parameters of self-administration of cocaine in rats under a progressive-ratio schedule. Pharmacol Biochem Behav 45:539-548.
27. 1A receptor agonists: recent developments and controversial issues. Psychopharmacology (Berl) 121:1-26.
28. Emmett-Oglesby MW, Lane JD (1993) Tolerance to self-administration of cocaine in rats: time course and dose-response determination using a multi-dose method. Drug Alcohol Depend 32:247-256.
29. Glennon RA, Dukat M (1991) Serotonin receptors and their ligands: a lack of selective agents. Pharmacol Biochem Behav 40:1009-1017.
30. Gongora-Alfaro JL, Hernandez-Lopez S, Flores-Hernandez J, Galarraga E (1997) Firing frequency modulation of substantia nigra reticulata neurons by 5-hydroxytryptamine. Neurosci Res 29:225-231.
31. Hodos W (1961) Progressive-ratio as a measure of reward strength. Science 134:943-944.
32. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PPA (1994) International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 46:157-203.
33. Hubner CB, Koob GF (1990) The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat. Brain Res 508:20-29.
34. 1b receptors block the GABAb synaptic potential in rat dopamine neurons. J Neurosci 12:2000-2006.
35. 1B receptor: binding studies in rat brain membranes. J Neurochem 58:1268-1276.
36. 1B receptor agonist CP-94,253. Drug Dev Res 26:241-250.
37. Koob GF, Bloom FE (1988) Molecular and cellular mechanisms of drug dependence. Science 242:715-723.
38. Kuhar ML, Ritz MC, Boja JW (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14:299-302.
39. 1A receptors in rat brain. Synapse 18:359-366.
40. Levy AD, Rittenhouse PA, Li Q, Bonadonna AM, Alvarez Sanz MC, Kerr JE, Bethea CL, Van de Kar LD (1992) Repeated injections of cocaine inhibit the serotonergic regulation of prolactin and renin secretion in rats. Brain Res 580:6-11.
41. Li M-Y, Yan Q-S, Coffey LL, Reith MEA (1996) Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers. J Neurochem 66:559-568.
42. Loh EA, Roberts DCS (1990) Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacology (Berl) 101:262-266.
43. 1B/1D antagonist GR127935. Mol Pharmacol 51:755-763.
44. 1A receptors in the dorsal raphe nucleus. Eur J Pharmacol 149:9-15.
45. 1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole. J Med Chem 33:2087-2093.
46. Markou A, Weiss F, Gold LH, Caine SB, Schulteis G, Koob GF (1993) Animal models of drug craving. Psychopharmacology (Berl) 112:163-182.
47. O'Connell MT, Curzon G (1996) A comparison of the effects of 8-OH-DPAT pretreatment of different behavioural responses to 8-OH-DPAT. Eur J Pharmacol 312:137-143.
48. Parsons LH, Smith AD, Justice Jr JB (1991) Basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine. Synapse 9:60-65.
49. Parsons LH, Koob GF, Weiss F (1995) Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. J Pharmacol Exp Ther 274:1182-1191.
50. Parsons LH, Weiss F, Koob GF (1996) Serotonin-1B receptor stimulation enhances dopamine-mediated reinforcement. Psychopharmacology (Berl) 128:150-160.
51. 1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine. Synapse, in press.
52. 1B/D receptor antagonists. Gen Pharmacol 29:293-303.
53. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates, 2nd Edition. San Diego: Academic.
54. 1B receptor knock out-behavioral consequences. Behav Brain Res 73:305-312.
55. Ranaldi R, French E, Roberts DCS (1996) Systemic pretreatment with MK-801 (dizocilpine) increases breaking points for self-administration of cocaine on a progressive-ratio schedule in rats. Psychopharmacology (Berl) 128:83-88.
56. Richardson NR, Roberts DCS (1991) Fluoxetine pretreatment reduces breaking points on a progressive ratio schedule reinforced by intravenous cocaine self-administration. Life Sci 49:833-840.
57. Richardson NR, Roberts DCS (1996) Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy. J Neurosci Methods 66:1-11.
58. Roberts DCS, Loh E, Vickers G (1989) Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment. Psychopharmacology (Berl) 97:535-538.
59. Robledo P, Koob GF (1993) Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat. Behav Brain Res 55:159-166.
60. Rocha BA, Ator R, Emett-Oglesby MW, Hen R (1997) Intravenous cocaine self-administration in mice lacking 5-HT1B receptors. Pharmacol Biochem Behav 57:407-412.
61. Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler JC, Hen R (1998) Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature 393:175-178.
62. Rodefer JS, Carroll ME (1996) Progressive ratio and behavioral economic evaluation of the reinforcing efficacy of orally delivered phencyclidine and ethanol in monkeys: effects of feeding conditions. Psychopharmacology (Berl) 128:265-273.
63. Rowlett JK, Massey BW, Kleven MS, Woolverton WL (1996) Parametric analysis of cocaine self-administration under a progressive-ratio schedule in rhesus monkeys. Psychopharmacology (Berl) 125:361-370.
64. Satel SL, Krystal JH, Delgado PL, Kosten TR, Charmey DS (1995) Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry 152:778-783.
65. Simms D, Gallagher JP (1996) Modification of serotonin responses in rat dorsolateral septal nucleus neurons by acute and chronic cocaine. J Pharmacol Exp Ther 276:1292-1303.
66. Skingle M, Scopes DIC, Feniuk W, Connor HE, Carter MC, Clitherow JW, Tyers MB (1993) GR 127935: a potent orally active 5-HT1D receptor antagonist. Br J Pharmacol 110:9P.
67. 1D receptor antagonist. Behav Brain Res 73:157-161.
68. 1A selective drugs on the 5-HT behavioral syndrome. Pharmacol Biochem Behav 24:1513-1519.
69. Spealman RD (1993) Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology (Berl) 112:93-99.
70. Thielen RJ, Fangon NB, Frazer A (1996) 4-(2′-Methoxyphenyl)-1-[(2″-pyridinyl)-p-iodobenzamido]piperazine and 4-(2′-methoxyphenyl)-1-[2′-[N(2″-pyridinyl)-p-fluorobenzamido] ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. J Pharmacol Exp Ther 277:661-670.
71. 1 receptor agonist, RU-24969, in the rat. Neuropharmacology 25:877-886.
72. Tsou AP, Kosaka A, Bach C, Zuppan P, Yee C, Tom L, Alvarez R, Ramsey S, Bonhaus DW, Stefanich E, Jakeman L, Eglen RM, Chan HW (1994) Cloning and expression of a 5-hydroxytryptamine7 receptor positively coupled to adenylyl cyclase. J Neurochem 63:456-464.
73. Van Wijngaarden I, Tulp MThM, Soudijn W (1990) The concept of selectivity in 5-HT receptor research. Eur J Pharmacol 188:301-312.
74. Walsh SL, Cunningham KA (1997) Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology (Berl) 130:41-58.
75. Walsh SL, Preston KL, Sullivan JT, Fromme R, Bigelow GE (1994) Fluoxetine alters the effects of intravenous cocaine in humans. J Clin Psychopharmacol 14:396-407.
76. Weiss F, Parsons LH, Markou A (1995) Neurochemistry of cocaine withdrawal. In: The neurobiology of cocaine: cellular and molecular mechanisms (Hammer Jr RP, ed), pp 163-180. Boca Raton, FL: CRC.
77. White FJ, Hu X-T, Henry DJ (1993) Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies. J Pharmacol Exp Ther 266:1075-1084.
78. White FJ, Hu X-T, Henry DJ, Zhang X-F (1995) Neurophysiological alterations in the mesocorticolimbic dopamine system with repeated cocaine administration. In: The neurobiology of cocaine: cellular and molecular mechanisms (Hammer Jr RP, ed), pp 99-120. Boca Raton, FL: CRC.
79. Wise RA (1984) Neural mechanisms of the reinforcing action of cocaine. In: Cocaine: pharmacology, effects and treatment of abuse, Vol 50, National Institute on Drug Abuse Research Monograph Series (Grabowski J, ed), pp 15-33. Washington, DC: United States Government Printing Office.
80. Woods JH, Herling S, Winger G (1978) Chlorpromazine- and haloperidol-induced changes in some behavioral effects of cocaine and amphetamine. In: Proceedings of the 10th Congress Collegium Internationale Neuropsychopharmacologicum (Deniker P, Radauco-Thomas D, Villeneuve A, eds), pp 1485-1502. New York: Pergamon.
81. Woods JH, Winger G, France CP (1987) Reinforcing and discriminative stimulus effects of cocaine: analysis and pharmacological mechanisms. In: Cocaine: clinical and biobehavioral aspects (Fisher S, Raskin A, Uhlenhuth EH, eds), pp 21-65. New York: Oxford UP.
82. Woolverton WL (1995) Comparison of the reinforcing effects of cocaine and procainc in rhesus monkeys responding under a progressive-ratio schedule. Psychopharmacology (Berl) 120:296-302.
83. 7 receptors mediate serotonergic effects on light-sensitive suprachiasmatic nucleus neurons. Brain Res 755:246-254.
84. Zito KA, Vickers G, Roberts DCS (1985) Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens. Pharmacol Biochem Behav 23:1029-1036.