Dopamine β-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine

Neuropsychopharmacology

Volumn 31, Issue 10, 2006, Pages 2221-2230

  Schank, Jesse R ^a   Ventura, Rossella ^b,c   Puglisi Allegra, Stefano ^b,c   Alcaro, Antonio ^b,c   Cole, Charlene D ^a,d   Liles, L Cameron ^a   Seeman, Philip ^e   Weinshenker, David ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^d EMORY UNIVERSITY   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Amphetamine; Cocaine; Dopamine; Dopamine hydroxylase; Mice; Norepinephrine

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; AMPHETAMINE; COCAINE; DISULFIRAM; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE BETA MONOOXYGENASE; DOPAMINE RECEPTOR BLOCKING AGENT; ETICLOPRIDE; KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NORADRENALIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; AVERSIVE BEHAVIOR; CAUDATE NUCLEUS; CELL FUNCTION; CONDITIONING; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENETIC REGULATION; HYPERSENSITIVITY; KNOCKOUT MOUSE; LOCOMOTION; MALE; MESENCEPHALON; MOUSE; MOUSE STRAIN; NONHUMAN; NORADRENERGIC SYSTEM; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOMOTOR ACTIVITY; RECEPTOR AFFINITY; RECEPTOR DENSITY; REWARD; SIGNAL TRANSDUCTION;

AMPHETAMINE; ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CONDITIONING, OPERANT; DOPAMINE; DOPAMINE BETA-HYDROXYLASE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; MALE; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRODIALYSIS; MOTOR ACTIVITY; NEURONS; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; PROTEIN BINDING; RADIOLIGAND ASSAY; SIGNAL TRANSDUCTION;

EID: 33748770069     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301000     Document Type: Article

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