-
1
-
-
0033586375
-
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: A double-blind placebo-controlled trial
-
Alton, E.W., Stern, M., Farley, R., 1999. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis:a double-blind placebo-controlled trial. Lancet, 353:947–54.
-
(1999)
Lancet
, vol.353
, pp. 947-954
-
-
Alton, E.W.1
Stern, M.2
Farley, R.3
-
2
-
-
34848903876
-
Plasmid DNA and viral vector-based vaccines for the treatment of cancer
-
Anderson, R.J., and Schneider, J., 2007. Plasmid DNA and viral vector-based vaccines for the treatment of cancer. Vaccine, 25:B24–34.
-
(2007)
Vaccine
, vol.25
, pp. B24-B34
-
-
Anderson, R.J.1
Schneider, J.2
-
3
-
-
51549089747
-
Affinity partitioning of plasmid DNA with a zinc finger protein
-
Barbosa, H., Hine, A. V., Brocchini, S., Slater, N.K., and Marcos, J.C., 2008. Affinity partitioning of plasmid DNA with a zinc finger protein. Journal of Chromatography A, 1206:105–12.
-
(2008)
Journal of Chromatography A
, vol.1206
, pp. 105-112
-
-
Barbosa, H.1
Hine, A.V.2
Brocchini, S.3
Slater, N.K.4
Marcos, J.C.5
-
4
-
-
4344612043
-
Characterization of methacrylate monoliths for purification of DNA molecules
-
Bencina, M., Podgornik, A., and Strancar, A., 2004. Characterization of methacrylate monoliths for purification of DNA molecules. Journal of Separation Science, 27:801–10.
-
(2004)
Journal of Separation Science
, vol.27
, pp. 801-810
-
-
Bencina, M.1
Podgornik, A.2
Strancar, A.3
-
5
-
-
0018800089
-
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
-
Birnboim, H.C., and Doly, J., 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Research, 7:1513–23.
-
(1979)
Nucleic Acids Research
, vol.7
, pp. 1513-1523
-
-
Birnboim, H.C.1
Doly, J.2
-
6
-
-
33947170041
-
Encapsulation of nucleic acids and opportunities for cancer treatment
-
Brannon-Peppas, L., Ghosn, B., Roy, K., and Cornetta, K., 2007. Encapsulation of nucleic acids and opportunities for cancer treatment. Pharmaceutical Research, 24:618–27.
-
(2007)
Pharmaceutical Research
, vol.24
, pp. 618-627
-
-
Brannon-Peppas, L.1
Ghosn, B.2
Roy, K.3
Cornetta, K.4
-
7
-
-
1642441457
-
Application of short monolithic columns for fast purification of plasmid DNA
-
Branovic, K., Forcic, D., Ivancic, J., 2004. Application of short monolithic columns for fast purification of plasmid DNA. Journal of Chromatography B, 801:331–7.
-
(2004)
Journal of Chromatography B
, vol.801
, pp. 331-337
-
-
Branovic, K.1
Forcic, D.2
Ivancic, J.3
-
8
-
-
59249092022
-
Muscular gene transfer using nonviral vectors
-
Braun, S., 2008. Muscular gene transfer using nonviral vectors. Current Gene Therapy, 8:391–405.
-
(2008)
Current Gene Therapy
, vol.8
, pp. 391-405
-
-
Braun, S.1
-
9
-
-
33847218598
-
Vaccine delivery methods using viral vectors
-
Brave, A., Ljungberg, K., Wahren, B., and Liu, M.A., 2007. Vaccine delivery methods using viral vectors. Molecular Pharmaceutics, 4:18–32.
-
(2007)
Molecular Pharmaceutics
, vol.4
, pp. 18-32
-
-
Brave, A.1
Ljungberg, K.2
Wahren, B.3
Liu, M.A.4
-
10
-
-
0020791017
-
A novel chromatographic procedure for purification of bacterial plasmids
-
Bywater, M., Bywater, R., and Hellman, L., 1983. A novel chromatographic procedure for purification of bacterial plasmids. Analytical Biochemistry, 132:219–24.
-
(1983)
Analytical Biochemistry
, vol.132
, pp. 219-224
-
-
Bywater, M.1
Bywater, R.2
Hellman, L.3
-
11
-
-
26644441231
-
Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture
-
Cano, T., Murphy, J. C., Fox, G.E., and Willson, R.C., 2005. Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture. Biotechnology Progress, 21:1472–7.
-
(2005)
Biotechnology Progress
, vol.21
, pp. 1472-1477
-
-
Cano, T.1
Murphy, J.C.2
Fox, G.E.3
Willson, R.C.4
-
12
-
-
85024147267
-
Fermentation process for continuous plasmid production
-
Carnes, A.E. (2007). Fermentation process for continuous plasmid production. WO 2007/089873
-
(2007)
WO
-
-
Carnes, A.E.1
-
13
-
-
33750621478
-
Inducible Escherichia coli fermentation for increased plasmid DNA production
-
Carnes, A.E., Hodgson, C.P., and Williams, J.A., 2006. Inducible Escherichia coli fermentation for increased plasmid DNA production. Biotechnology and Applied Biochemistry, 45:155–66.
-
(2006)
Biotechnology and Applied Biochemistry
, vol.45
, pp. 155-166
-
-
Carnes, A.E.1
Hodgson, C.P.2
Williams, J.A.3
-
16
-
-
33750574751
-
Ultra scaledown studies of the effect of flow and impact conditions during E. coli cell processing
-
Chan, G., Booth, A. J., Mannweiler, K., and Hoare, M., 2006. Ultra scaledown studies of the effect of flow and impact conditions during E. coli cell processing. Biotechnology and Bioengineering, 95:671–83.
-
(2006)
Biotechnology and Bioengineering
, vol.95
, pp. 671-683
-
-
Chan, G.1
Booth, A.J.2
Mannweiler, K.3
Hoare, M.4
-
17
-
-
0026666888
-
Large-scale purification of plasmid DNA by fast protein liquid chromatography using a Hi-Load Q Sepharose column
-
Chandra, G., Patel, P., Kost, T.A., and Gray, J.G., 1992. Large-scale purification of plasmid DNA by fast protein liquid chromatography using a Hi-Load Q Sepharose column. Analytical Biochemistry, 203:169–72.
-
(1992)
Analytical Biochemistry
, vol.203
, pp. 169-172
-
-
Chandra, G.1
Patel, P.2
Kost, T.A.3
Gray, J.G.4
-
18
-
-
37549056600
-
Efficient expression of vascular endothelial growth factor using minicircle DNA for angiogenic gene therapy
-
Chang, C.W., Christensen, L. V., Lee, M., and Kim, S.W., 2008. Efficient expression of vascular endothelial growth factor using minicircle DNA for angiogenic gene therapy. Journal of Controlled Release, 125:155–63.
-
(2008)
Journal of Controlled Release
, vol.125
, pp. 155-163
-
-
Chang, C.W.1
Christensen, L.V.2
Lee, M.3
Kim, S.W.4
-
19
-
-
85024162711
-
Process for large-scale production of plasmid DNA by E. coli fermentation
-
CHARTRAIN, M., KIZER L. E. KRULEWICZ, B.A. ET AL. (2005). Process for large-scale production of plasmid DNA by E. coli fermentation. WO/2005/078115
-
(2005)
WO/2005/078115
-
-
Chartrain, M.1
Kizer, L.E.K.2
-
20
-
-
0032790308
-
Effect of DNA topology on the transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes
-
Cherng, J.Y., Schuurmans-Nieuwenbroek, N.M., Jiskoot, W., 1999. Effect of DNA topology on the transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes. Journal of Controlled Release, 60:343–53.
-
(1999)
Journal of Controlled Release
, vol.60
, pp. 343-353
-
-
Cherng, J.Y.1
Schuurmans-Nieuwenbroek, N.M.2
Jiskoot, W.3
-
23
-
-
7444233825
-
Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines
-
Cooke, J.R., Mckie, E. A., Ward, J.M., and Keshavarz-Moore, E., 2004. Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines. Journal of Biotechnology, 114:239–54.
-
(2004)
Journal of Biotechnology
, vol.114
, pp. 239-254
-
-
Cooke, J.R.1
McKie, E.A.2
Ward, J.M.3
Keshavarz-Moore, E.4
-
24
-
-
14244251286
-
Impact of plasmid supercoiling on the efficacy of a rabies DNA vaccine to protect cats
-
Cupillard, L., Juillard, V., Latour, S., 2005. Impact of plasmid supercoiling on the efficacy of a rabies DNA vaccine to protect cats. Vaccine, 23:1910–6.
-
(2005)
Vaccine
, vol.23
, pp. 1910-1916
-
-
Cupillard, L.1
Juillard, V.2
Latour, S.3
-
25
-
-
36749084045
-
Affinity purification of plasmid DNA directly from crude bacterial cell lysates
-
Darby, R.A., Forde, G. M., Slater, N.K., and Hine, A.V., 2007. Affinity purification of plasmid DNA directly from crude bacterial cell lysates. Biotechnology and Bioengineering, 98:1103–8.
-
(2007)
Biotechnology and Bioengineering
, vol.98
, pp. 1103-1108
-
-
Darby, R.A.1
Forde, G.M.2
Slater, N.K.3
Hine, A.V.4
-
26
-
-
13844267789
-
Adsorptive purification of pDNA on superporous rigid cross-linked cellulose matrix
-
Deshmukh, N.R., and Lali, A.M., 2005. Adsorptive purification of pDNA on superporous rigid cross-linked cellulose matrix. Journal of Chromatography B, 818:5–10.
-
(2005)
Journal of Chromatography B
, vol.818
, pp. 5-10
-
-
Deshmukh, N.R.1
Lali, A.M.2
-
27
-
-
0033231382
-
Separation and analysis of plasmid denatured forms using hydrophobic interaction chromatography
-
Diogo, M.M., Queiroz, J. A., Monteiro, G.A., and Prazeres, D.M.F., 1999. Separation and analysis of plasmid denatured forms using hydrophobic interaction chromatography. Analytical Biochemistry, 275:122–4.
-
(1999)
Analytical Biochemistry
, vol.275
, pp. 122-124
-
-
Diogo, M.M.1
Queiroz, J.A.2
Monteiro, G.A.3
Prazeres, D.M.F.4
-
28
-
-
0034608587
-
Purification of a cystic fibrosis plasmid vector for gene therapy using hydrophobic interaction chromatography
-
Diogo, M.M., Queiroz, J. A., Monteiro, G.A., 2000. Purification of a cystic fibrosis plasmid vector for gene therapy using hydrophobic interaction chromatography. Biotechnology and Bioengineering, 68:576–83.
-
(2000)
Biotechnology and Bioengineering
, vol.68
, pp. 576-583
-
-
Diogo, M.M.1
Queiroz, J.A.2
Monteiro, G.A.3
-
29
-
-
0035554023
-
Studies on the retention of plasmid DNA and Escherichia coli nucleic acids by hydrophobic interaction chromatography
-
Diogo, M.M., Queiroz, J.A., and Prazeres, D.M.F., 2001a. Studies on the retention of plasmid DNA and Escherichia coli nucleic acids by hydrophobic interaction chromatography. Bioseparation, 10:211–20.
-
(2001)
Bioseparation
, vol.10
, pp. 211-220
-
-
Diogo, M.M.1
Queiroz, J.A.2
Prazeres, D.M.F.3
-
30
-
-
0035523565
-
Production, purification and analysis of an experimental DNA vaccine against rabies
-
Diogo, M.M., Ribeiro, S. C., Queiroz, J.A., 2001b. Production, purification and analysis of an experimental DNA vaccine against rabies. Journal of Gene Medicine, 3:577–84.
-
(2001)
Journal of Gene Medicine
, vol.3
, pp. 577-584
-
-
Diogo, M.M.1
Ribeiro, S.C.2
Queiroz, J.A.3
-
31
-
-
0038392599
-
Assessment of purity and quantification of plasmid DNA in process solutions using high-performance hydrophobic interaction chromatography
-
Diogo, M.M., Queiroz, J.A., and Prazeres, D.M.F., 2003. Assessment of purity and quantification of plasmid DNA in process solutions using high-performance hydrophobic interaction chromatography. Journal of Chromatography A, 998:109–17.
-
(2003)
Journal of Chromatography A
, vol.998
, pp. 109-117
-
-
Diogo, M.M.1
Queiroz, J.A.2
Prazeres, D.M.F.3
-
32
-
-
15244358693
-
Chromatography of plasmid DNA
-
Diogo, M.M., Queiroz, J.A., and Prazeres, D.M.F., 2005. Chromatography of plasmid DNA. Journal of Chromatography A, 1069:3–22.
-
(2005)
Journal of Chromatography A
, vol.1069
, pp. 3-22
-
-
Diogo, M.M.1
Queiroz, J.A.2
Prazeres, D.M.F.3
-
33
-
-
33646830816
-
Epidermal DNA vaccine for influenza is immunogenic in humans
-
Drape, R.J., Macklin, M. D., Barr, L.J., 2006. Epidermal DNA vaccine for influenza is immunogenic in humans. Vaccine, 24:4475–81.
-
(2006)
Vaccine
, vol.24
, pp. 4475-4481
-
-
Drape, R.J.1
Macklin, M.D.2
Barr, L.J.3
-
34
-
-
0037402921
-
Removal of RNA impurities by tangential flow filtration in an RNase-free plasmid DNA purification process
-
Eon-Duval, A., Macduff, R. H., Fisher, C. A., Harris, M.J., and Brook, C., 2003. Removal of RNA impurities by tangential flow filtration in an RNase-free plasmid DNA purification process. Analytical Biochemistry, 316:66–73.
-
(2003)
Analytical Biochemistry
, vol.316
, pp. 66-73
-
-
Eon-Duval, A.1
Macduff, R.H.2
Fisher, C.A.3
Harris, M.J.4
Brook, C.5
-
35
-
-
1842787939
-
Purification of pharmaceutical-grade plasmid DNA by anion-exchange chromatography in an RNase-free process
-
Eon-Duval, A., and Burke, G., 2004. Purification of pharmaceutical-grade plasmid DNA by anion-exchange chromatography in an RNase-free process. Journal of Chromatography B, 804:327–35.
-
(2004)
Journal of Chromatography B
, vol.804
, pp. 327-335
-
-
Eon-Duval, A.1
Burke, G.2
-
36
-
-
0027248058
-
A modified alkaline lysis method for the preparation of highly purified plasmid DNA from Escherichia coli
-
Feliciello, I., and Chinali, G., 1993. A modified alkaline lysis method for the preparation of highly purified plasmid DNA from Escherichia coli. Analytical Biochemistry, 212:394–401.
-
(1993)
Analytical Biochemistry
, vol.212
, pp. 394-401
-
-
Feliciello, I.1
Chinali, G.2
-
37
-
-
0030968156
-
A comparison of gel filtration chromatographic supports for plasmid purification
-
Ferreira, G.N., Cabral, J.M., and Prazeres, D.M.F., 1997. A comparison of gel filtration chromatographic supports for plasmid purification. Biotechnology Techniques, 11:417–420.
-
(1997)
Biotechnology Techniques
, vol.11
, pp. 417-420
-
-
Ferreira, G.N.1
Cabral, J.M.2
Prazeres, D.M.F.3
-
38
-
-
0033167256
-
Development of process flow sheets for the purification of supercoiled plasmids for gene therapy applications
-
Ferreira, G.N., Cabral, J.M., and Prazeres, D.M.F., 1999. Development of process flow sheets for the purification of supercoiled plasmids for gene therapy applications. Biotechnology Progress, 15:725–31.
-
(1999)
Biotechnology Progress
, vol.15
, pp. 725-731
-
-
Ferreira, G.N.1
Cabral, J.M.2
Prazeres, D.M.F.3
-
39
-
-
0034284422
-
Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications
-
Ferreira, G.N., Monteiro, G. A., Prazeres, D.M.F., and Cabral, J.M., 2000. Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications. Trends in Biotechnology, 18:380–8.
-
(2000)
Trends in Biotechnology
, vol.18
, pp. 380-388
-
-
Ferreira, G.N.1
Monteiro, G.A.2
Prazeres, D.M.F.3
Cabral, J.M.4
-
40
-
-
4344663365
-
Growth-rate recovery of Escherichia coli cultures carrying a multicopy plasmid, by engineering of the pentose-phosphate pathway
-
Flores, S., De Anda-Herrera, R., Gosset, G., and Bolivar, F.G., 2004. Growth-rate recovery of Escherichia coli cultures carrying a multicopy plasmid, by engineering of the pentose-phosphate pathway. Biotechnology and Bioengineering, 87:485–94.
-
(2004)
Biotechnology and Bioengineering
, vol.87
, pp. 485-494
-
-
Flores, S.1
De Anda-Herrera, R.2
Gosset, G.3
Bolivar, F.G.4
-
41
-
-
33748433378
-
LacO-LacI interaction in affinity adsorption of plasmid DNA
-
Forde, G.M., Ghose, S., Slater, N.K., 2006. LacO-LacI interaction in affinity adsorption of plasmid DNA. Biotechnology and Bioengineering, 95:67–75.
-
(2006)
Biotechnology and Bioengineering
, vol.95
, pp. 67-75
-
-
Forde, G.M.1
Ghose, S.2
Slater, N.K.3
-
42
-
-
0032528715
-
High-performance membrane chromatography of supercoiled plasmid DNA
-
Giovannini, R., Freitag, R., and Tennikova, T.B., 1998. High-performance membrane chromatography of supercoiled plasmid DNA. Analytical Chemistry, 70:3348–54.
-
(1998)
Analytical Chemistry
, vol.70
, pp. 3348-3354
-
-
Giovannini, R.1
Freitag, R.2
Tennikova, T.B.3
-
43
-
-
50549093286
-
Gene transfer: The challenge of regulated gene expression
-
Guo, Z.S., Li, Q., Bartlett, D. L., Yang, J.Y., and Fang, B., 2008. Gene transfer:the challenge of regulated gene expression. Trends in Molecular Medicine, 14:410–8.
-
(2008)
Trends in Molecular Medicine
, vol.14
, pp. 410-418
-
-
Guo, Z.S.1
Li, Q.2
Bartlett, D.L.3
Yang, J.Y.4
Fang, B.5
-
44
-
-
0034046182
-
DNA vaccines: Immunology, application, and optimization
-
Gurunathan, S., Klinman, D.M., and Seder, R.A., 2000. DNA vaccines:immunology, application, and optimization. Annual Review of Immunology, 18:27–74.
-
(2000)
Annual Review of Immunology
, vol.18
, pp. 27-74
-
-
Gurunathan, S.1
Klinman, D.M.2
Seder, R.A.3
-
45
-
-
0032927212
-
Superporous agarose beads as a hydrophobic interaction chromatography support
-
Gustavsson, P.E., Axelsson, A., and Larsson, P.O., 1999. Superporous agarose beads as a hydrophobic interaction chromatography support. Journal of Chromatography A, 830:275–284.
-
(1999)
Journal of Chromatography A
, vol.830
, pp. 275-284
-
-
Gustavsson, P.E.1
Axelsson, A.2
Larsson, P.O.3
-
46
-
-
2442530783
-
Purification of plasmid DNA with a new type of anion-exchange beads having a non-charged surface
-
Gustavsson, P.E., Lemmens, R., Nyhammar, T., Busson, P., and Larsson, P.O., 2004. Purification of plasmid DNA with a new type of anion-exchange beads having a non-charged surface. Journal of Chromatography A, 1038:131–40.
-
(2004)
Journal of Chromatography A
, vol.1038
, pp. 131-140
-
-
Gustavsson, P.E.1
Lemmens, R.2
Nyhammar, T.3
Busson, P.4
Larsson, P.O.5
-
48
-
-
53249083853
-
Single step purification of plasmid DNA using peptide ligand affinity chromatography
-
Han, Y., and Forde, G.M., 2008. Single step purification of plasmid DNA using peptide ligand affinity chromatography. Journal of Chromatography B, 874:21–6.
-
(2008)
Journal of Chromatography B
, vol.874
, pp. 21-26
-
-
Han, Y.1
Forde, G.M.2
-
49
-
-
20444415980
-
Immobilisation of a repressor protein for binding of plasmid DNA
-
Hasche, A, and Voss, C., 2005. Immobilisation of a repressor protein for binding of plasmid DNA. Journal of Chromatography A, 1080:76–82.
-
(2005)
Journal of Chromatography A
, vol.1080
, pp. 76-82
-
-
Hasche, A.1
Voss, C.2
-
51
-
-
28844490036
-
Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100 m3 fermentation scale for an influenza pandemic
-
Hoare, M., Levy, M. S., Bracewell, D.G., 2005. Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100 m3 fermentation scale for an influenza pandemic. Biotechnology Progress, 21:1577–92.
-
(2005)
Biotechnology Progress
, vol.21
, pp. 1577-1592
-
-
Hoare, M.1
Levy, M.S.2
Bracewell, D.G.3
-
52
-
-
0019862344
-
A rapid boiling method for the preparation of bacterial plasmids
-
Holmes, D.S., and Quigley, M., 1981. A rapid boiling method for the preparation of bacterial plasmids. Analytical Biochemistry, 114:193–7.
-
(1981)
Analytical Biochemistry
, vol.114
, pp. 193-197
-
-
Holmes, D.S.1
Quigley, M.2
-
53
-
-
0028978028
-
Cancer gene therapy using plasmid DNA: Purification of DNA for human clinical trials
-
Horn, N.A., Meek, J. A., Budahazi, G., and Marquet, M., 1995. Cancer gene therapy using plasmid DNA:purification of DNA for human clinical trials. Human Gene Therapy, 6:565–73.
-
(1995)
Human Gene Therapy
, vol.6
, pp. 565-573
-
-
Horn, N.A.1
Meek, J.A.2
Budahazi, G.3
Marquet, M.4
-
54
-
-
34547554168
-
Biopharmaceuticals in China
-
Hu, X., Ma, Q., and Zhang, S., 2006. Biopharmaceuticals in China. Biotechnology Journal, 1:1215–24.
-
(2006)
Biotechnology Journal
, vol.1
, pp. 1215-1224
-
-
Hu, X.1
Ma, Q.2
Zhang, S.3
-
56
-
-
0037183740
-
Rapid analysis of a plasmid by hydrophobic-interaction chromatography with a non-porous resin
-
Iuliano, S., Fisher, J. R., Chen, M., and Kelly, W.J., 2002. Rapid analysis of a plasmid by hydrophobic-interaction chromatography with a non-porous resin. Journal of Chromatography A, 972:77–86.
-
(2002)
Journal of Chromatography A
, vol.972
, pp. 77-86
-
-
Iuliano, S.1
Fisher, J.R.2
Chen, M.3
Kelly, W.J.4
-
57
-
-
4344678036
-
Monoliths for fast bioseparation and bioconversion and their applications in biotechnology
-
Jungbauer, A., and Hahn, R., 2004. Monoliths for fast bioseparation and bioconversion and their applications in biotechnology. Journal of Separation Science, 27:767–78.
-
(2004)
Journal of Separation Science
, vol.27
, pp. 767-778
-
-
Jungbauer, A.1
Hahn, R.2
-
58
-
-
39749156913
-
Polymethacrylate monoliths for preparative and industrial separation of biomolecular assemblies
-
Jungbauer, A., and Hahn, R., 2008. Polymethacrylate monoliths for preparative and industrial separation of biomolecular assemblies. Journal of Chromatography A, 1184:62–79.
-
(2008)
Journal of Chromatography A
, vol.1184
, pp. 62-79
-
-
Jungbauer, A.1
Hahn, R.2
-
59
-
-
20444483268
-
Hydrophobic interaction chromatography of proteins. III. Unfolding of proteins upon adsorption
-
Jungbauer, A., Machold, C., and Hahn, R., 2005. Hydrophobic interaction chromatography of proteins. III. Unfolding of proteins upon adsorption. Journal of Chromatography A, 1079:221–8.
-
(2005)
Journal of Chromatography A
, vol.1079
, pp. 221-228
-
-
Jungbauer, A.1
Machold, C.2
Hahn, R.3
-
60
-
-
5144221446
-
A potential disruptive technology in vaccine development: Gene-based vaccines and their application to infectious diseases
-
Kaslow, DC. 2004. A potential disruptive technology in vaccine development:gene-based vaccines and their application to infectious diseases. Transactions of the Royal Society of Tropical Medicine and Hygiene, 98:593–601.
-
(2004)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.98
, pp. 593-601
-
-
Kaslow, D.C.1
-
61
-
-
0033055999
-
DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice
-
Kodihalli, S., Goto, H., Kobasa, D.L., 1999. DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice. The Journal of Virology, 73:2094–8.
-
(1999)
The Journal of Virology
, vol.73
, pp. 2094-2098
-
-
Kodihalli, S.1
Goto, H.2
Kobasa, D.L.3
-
62
-
-
51149095172
-
Large-scale plasmid DNA processing: Evidence that cell harvesting and storage methods affect yield of supercoiled plasmid DNA
-
Kong, S., Rock, C. F., Booth, A., 2008. Large-scale plasmid DNA processing:evidence that cell harvesting and storage methods affect yield of supercoiled plasmid DNA. Biotechnology and Applied Biochemistry, 51:43–51.
-
(2008)
Biotechnology and Applied Biochemistry
, vol.51
, pp. 43-51
-
-
Kong, S.1
Rock, C.F.2
Booth, A.3
-
63
-
-
0029796205
-
High-yield production of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation
-
Lahijani, R., Hulley, G., Soriano, G., Horn, N.A., and Marquet, M., 1996. High-yield production of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation. Human Gene Therapy, 7:1971–80.
-
(1996)
Human Gene Therapy
, vol.7
, pp. 1971-1980
-
-
Lahijani, R.1
Hulley, G.2
Soriano, G.3
Horn, N.A.4
Marquet, M.5
-
65
-
-
17144401470
-
Novel molecular approaches to cystic fibrosis gene therapy
-
Lee, T.W., Matthews, D.A., and Blair, G.E., 2005. Novel molecular approaches to cystic fibrosis gene therapy. Biochemical Journal, 387:1–15.
-
(2005)
Biochemical Journal
, vol.387
, pp. 1-15
-
-
Lee, T.W.1
Matthews, D.A.2
Blair, G.E.3
-
66
-
-
0034237305
-
Biochemical engineering approaches to the challenges of producing pure plasmid DNA
-
Levy, M.S., O'kennedy, R.D., Ayazi-Shamlou, P., and Dunnill, P., 2000. Biochemical engineering approaches to the challenges of producing pure plasmid DNA. Trends in Biotechnology, 18:296–305.
-
(2000)
Trends in Biotechnology
, vol.18
, pp. 296-305
-
-
Levy, M.S.1
O'kennedy, R.D.2
Ayazi-Shamlou, P.3
Dunnill, P.4
-
67
-
-
33845674679
-
Effect of salt on purification of plasmid DNA using size-exclusion chromatography
-
Li, L.Z., Liu, Y., Sun, M.S., and Shao, YM., 2007. Effect of salt on purification of plasmid DNA using size-exclusion chromatography. Journal of Chromatography A, 1139:228–35.
-
(2007)
Journal of Chromatography A
, vol.1139
, pp. 228-235
-
-
Li, L.Z.1
Liu, Y.2
Sun, M.S.3
Shao, Y.M.4
-
68
-
-
26044446666
-
High-speed chromatographic purification of plasmid DNA with a customized biporous hydrophobic adsorbent
-
Li, Y., Dong, X-Y., and Sun, Y., 2005. High-speed chromatographic purification of plasmid DNA with a customized biporous hydrophobic adsorbent. Biochemical Engineering Journal, 27:33–9.
-
(2005)
Biochemical Engineering Journal
, vol.27
, pp. 33-39
-
-
Li, Y.1
Dong, X.-Y.2
Sun, Y.3
-
69
-
-
0022528982
-
Effect of the bacterial growth rate on replication control of plasmid pBR322 in Escherichia coli
-
Lin-Chao, S., and Bremer, H., 1986. Effect of the bacterial growth rate on replication control of plasmid pBR322 in Escherichia coli. Molecular Genomics and Genetics, 203:143–9.
-
(1986)
Molecular Genomics and Genetics
, vol.203
, pp. 143-149
-
-
Lin-Chao, S.1
Bremer, H.2
-
70
-
-
33750018093
-
Development of a highly productive and scalable plasmid DNA production platform
-
Listner, K., Bentley, L., Okonkowski, J., 2006. Development of a highly productive and scalable plasmid DNA production platform. Biotechnology Progress, 22:1335–45.
-
(2006)
Biotechnology Progress
, vol.22
, pp. 1335-1345
-
-
Listner, K.1
Bentley, L.2
Okonkowski, J.3
-
72
-
-
0032998971
-
Direct visualisation of plasmid DNA in individual chromatography adsorbent particles by confocal scanning laser microscopy
-
Ljunglof, A., Bergvall, P., Bhikhabhai, R., and Hjorth, R., 1999. Direct visualisation of plasmid DNA in individual chromatography adsorbent particles by confocal scanning laser microscopy. Journal of Chromatography A, 844:129–35.
-
(1999)
Journal of Chromatography A
, vol.844
, pp. 129-135
-
-
Ljunglof, A.1
Bergvall, P.2
Bhikhabhai, R.3
Hjorth, R.4
-
73
-
-
0035975869
-
New developments in affinity chromatography with potential application in the production of biopharmaceuticals
-
Lowe, C.R., Lowe, A.R., and Gupta, G., 2001. New developments in affinity chromatography with potential application in the production of biopharmaceuticals. Journal of Biochemical and Biophysical Methods, 49:561–74.
-
(2001)
Journal of Biochemical and Biophysical Methods
, vol.49
, pp. 561-574
-
-
Lowe, C.R.1
Lowe, A.R.2
Gupta, G.3
-
75
-
-
33745107315
-
Plasmid vaccines and therapeutics: From design to applications
-
Manthorpe, M., Hobart, P., Hermanson, G., 2005. Plasmid vaccines and therapeutics:from design to applications. Advances in Biochemical Engineering Biotechnology, 99:41–92.
-
(2005)
Advances in Biochemical Engineering Biotechnology
, vol.99
, pp. 41-92
-
-
Manthorpe, M.1
Hobart, P.2
Hermanson, G.3
-
76
-
-
33846909686
-
A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial
-
Martin, J.E., Sullivan, N. J., Enama, M.E., 2006. A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial. Clinical and Vaccine Immunology, 13:1267–77.
-
(2006)
Clinical and Vaccine Immunology
, vol.13
, pp. 1267-1277
-
-
Martin, J.E.1
Sullivan, N.J.2
Enama, M.E.3
-
77
-
-
65849216592
-
Reversed-phase ion-pair liquid chromatography analysis and purification of small interfering RNA
-
In press
-
Mccarthy, S.M., Gilar, M., and Gebler, J., 2009. Reversed-phase ion-pair liquid chromatography analysis and purification of small interfering RNA. Analytical Biochemistry, In press
-
(2009)
Analytical Biochemistry
-
-
McCarthy, S.M.1
Gilar, M.2
Gebler, J.3
-
79
-
-
0022087345
-
Purification of RNA-free plasmid DNA using alkaline extraction followed by Ultrogel A2 column chromatography
-
Micard, D., Sobrier, M. L., Couderc, J.L., and Dastugue, B., 1985. Purification of RNA-free plasmid DNA using alkaline extraction followed by Ultrogel A2 column chromatography. Analytical Biochemistry, 148:121–6.
-
(1985)
Analytical Biochemistry
, vol.148
, pp. 121-126
-
-
Micard, D.1
Sobrier, M.L.2
Couderc, J.L.3
Dastugue, B.4
-
80
-
-
3543025721
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
-
Morishita, R., Aoki, M., Hashiya, N., 2004. Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension, 44:203–9.
-
(2004)
Hypertension
, vol.44
, pp. 203-209
-
-
Morishita, R.1
Aoki, M.2
Hashiya, N.3
-
81
-
-
0034159940
-
Gene therapy: The first decade
-
Mountain, A., 2000. Gene therapy:the first decade. Trends in Biotechnology, 18:119–28.
-
(2000)
Trends in Biotechnology
, vol.18
, pp. 119-128
-
-
Mountain, A.1
-
82
-
-
0032868745
-
Purification of plasmid DNA using selective precipitation by compaction agents
-
Murphy, J.C., Wibbenmeyer, J. A., Fox, G.E., and Willson, R.C., 1999. Purification of plasmid DNA using selective precipitation by compaction agents. Nature Biotechnology, 17:822–3.
-
(1999)
Nature Biotechnology
, vol.17
, pp. 822-823
-
-
Murphy, J.C.1
Wibbenmeyer, J.A.2
Fox, G.E.3
Willson, R.C.4
-
83
-
-
0037449377
-
Enhancement of anion-exchange chromatography of DNA using compaction agents
-
Murphy, J.C., Fox, G.E., and Willson, R.C., 2003a. Enhancement of anion-exchange chromatography of DNA using compaction agents. Journal of Chromatography A, 984:215–21.
-
(2003)
Journal of Chromatography A
, vol.984
, pp. 215-221
-
-
Murphy, J.C.1
Fox, G.E.2
Willson, R.C.3
-
84
-
-
0038458864
-
Nucleic acid separations utilizing immobilized metal affinity chromatography
-
Murphy, J.C., Jewell, D. L., White, K. I., Fox, G.E., and Wilsson, R.C., 2003b. Nucleic acid separations utilizing immobilized metal affinity chromatography. Biotechnology Progress, 19:982–6.
-
(2003)
Biotechnology Progress
, vol.19
, pp. 982-986
-
-
Murphy, J.C.1
Jewell, D.L.2
White, K.I.3
Fox, G.E.4
Wilsson, R.C.5
-
85
-
-
11144355460
-
A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: Stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans
-
Mwau, M., Cebere, I., Sutton, J., 2004. A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials:stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. Journal of General Virology, 85:911–9.
-
(2004)
Journal of General Virology
, vol.85
, pp. 911-919
-
-
Mwau, M.1
Cebere, I.2
Sutton, J.3
-
86
-
-
0033990746
-
Effects of growth medium selection on plasmid DNA production and initial processing steps
-
O'kennedy, R.D., Baldwin, C., and Keshavarz-Moore, E., 2000. Effects of growth medium selection on plasmid DNA production and initial processing steps. Journal of Biotechnology, 76:175–83.
-
(2000)
Journal of Biotechnology
, vol.76
, pp. 175-183
-
-
O'kennedy, R.D.1
Baldwin, C.2
Keshavarz-Moore, E.3
-
87
-
-
24044441888
-
Proposal for a better integration of bacterial lysis into the production of plasmid DNA at large scale
-
O'MAHONY, K., Freitag, R., Hilbrig, F., Muller, P., and Schumacher, I., 2005. Proposal for a better integration of bacterial lysis into the production of plasmid DNA at large scale. Journal of Biotechnology, 119:118–32.
-
(2005)
Journal of Biotechnology
, vol.119
, pp. 118-132
-
-
O'mahony, K.1
Freitag, R.2
Hilbrig, F.3
Muller, P.4
Schumacher, I.5
-
88
-
-
34547924887
-
Integration of bacteria capture via filtration and in situ lysis for recovery of plasmid DNA under industry-compatible conditions
-
O'Mahony, K., Freitag, R., Hilbrig, F., Schumacher, I., and Muller, P., 2007. Integration of bacteria capture via filtration and in situ lysis for recovery of plasmid DNA under industry-compatible conditions. Biotechnology Progress, 23:895–03.
-
(2007)
Biotechnology Progress
, vol.23
, pp. 895-803
-
-
O'Mahony, K.1
Freitag, R.2
Hilbrig, F.3
Schumacher, I.4
Muller, P.5
-
89
-
-
1842538713
-
Enhancement of p53 sequence-specific binding by DNA supercoiling
-
Palecek, E., Brazda, V., Jagelska, E., 2004. Enhancement of p53 sequence-specific binding by DNA supercoiling. Oncogene, 23:2119–27.
-
(2004)
Oncogene
, vol.23
, pp. 2119-2127
-
-
Palecek, E.1
Brazda, V.2
Jagelska, E.3
-
90
-
-
32944454986
-
Production of ColE1 type plasmid by Escherichia coli DH5 alpha cultured under nonselective conditions
-
Passarinha, L.A., Diogo, M. M., Queiroz, J.A. 2006. Production of ColE1 type plasmid by Escherichia coli DH5 alpha cultured under nonselective conditions. Journal of Microbiology and Biotechnology, 16:20–4.
-
(2006)
Journal of Microbiology and Biotechnology
, vol.16
, pp. 20-24
-
-
Passarinha, L.A.1
Diogo, M.M.2
Queiroz, J.A.3
-
91
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: A comprehensive review
-
Patil, S.D., Rhodes, D.G., and Burgess, D.J., 2005. DNA-based therapeutics and DNA delivery systems:a comprehensive review. The AAPS Journal, 7:E61–77.
-
(2005)
The AAPS Journal
, vol.7
, pp. E61-E77
-
-
Patil, S.D.1
Rhodes, D.G.2
Burgess, D.J.3
-
92
-
-
55549128624
-
Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha
-
Phue, J.N., Lee, S. J., Trinh, L., and Shiloach, J., 2008. Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha. Biotechnology Bioengineering, 101:831–6.
-
(2008)
Biotechnology Bioengineering
, vol.101
, pp. 831-836
-
-
Phue, J.N.1
Lee, S.J.2
Trinh, L.3
Shiloach, J.4
-
93
-
-
13844253750
-
Chromatographic investigation of macromolecular affinity interactions
-
Platonova, G.A., and Tennikova, TB., 2005. Chromatographic investigation of macromolecular affinity interactions. Journal of Chromatography A, 1065:75–81.
-
(2005)
Journal of Chromatography A
, vol.1065
, pp. 75-81
-
-
Platonova, G.A.1
Tennikova, T.B.2
-
94
-
-
50949129278
-
Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia
-
Powell, R.J., Simons, M., Mendelsohn, F.O., 2008. Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia. Circulation, 118:58–65.
-
(2008)
Circulation
, vol.118
, pp. 58-65
-
-
Powell, R.J.1
Simons, M.2
Mendelsohn, F.O.3
-
95
-
-
0242710545
-
Industrial scale production of plasmid DNA for vaccine and gene therapy: Plasmid design, production, and purification
-
Prather, K.J., Sagar, S., Murphy, J., and Chartrain, M., 2003. Industrial scale production of plasmid DNA for vaccine and gene therapy:plasmid design, production, and purification. Enzyme and Microbial Technology, 33:865–83.
-
(2003)
Enzyme and Microbial Technology
, vol.33
, pp. 865-883
-
-
Prather, K.J.1
Sagar, S.2
Murphy, J.3
Chartrain, M.4
-
96
-
-
0032496250
-
Preparative purification of supercoiled plasmid DNA using anion-exchange chromatography
-
Prazeres, D.M.F., Schluep, T., and Cooney, C., 1998. Preparative purification of supercoiled plasmid DNA using anion-exchange chromatography. Journal of Chromatography A, 806:31–45.
-
(1998)
Journal of Chromatography A
, vol.806
, pp. 31-45
-
-
Prazeres, D.M.F.1
Schluep, T.2
Cooney, C.3
-
97
-
-
0033120652
-
Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: Problems and bottlenecks
-
Prazeres, D.M.F., Ferreira, G. N., Monteiro, G. A., Cooney, C.L., and Cabral, J.M., 1999. Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy:problems and bottlenecks. Trends in Biotechnology, 17:169–74.
-
(1999)
Trends in Biotechnology
, vol.17
, pp. 169-174
-
-
Prazeres, D.M.F.1
Ferreira, G.N.2
Monteiro, G.A.3
Cooney, C.L.4
Cabral, J.M.5
-
98
-
-
0347899375
-
Design of flowsheets for the recovery and purification of plasmids for gene therapy and DNA vaccination
-
Prazeres, D.M.F., and Ferreira, G.N.M., 2004. Design of flowsheets for the recovery and purification of plasmids for gene therapy and DNA vaccination. Chemical Engineering Process, 43:615–30.
-
(2004)
Chemical Engineering Process
, vol.43
, pp. 615-630
-
-
Prazeres, D.M.F.1
Ferreira, G.N.M.2
-
99
-
-
34249942373
-
Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies
-
Przybylowski, M., Bartido, S., BORQUEZ-OJEDA, O., Sadelain, M., and Riviere, I., 2007. Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies. Vaccine, 25:5013–24.
-
(2007)
Vaccine
, vol.25
, pp. 5013-5024
-
-
Przybylowski, M.1
Bartido, S.2
Borquez-Ojeda, O.3
Sadelain, M.4
Riviere, I.5
-
100
-
-
0035805436
-
Hydrophobic interaction chromatography of proteins
-
Queiroz, J.A., Tomaz, C.T., and Cabral, J.M., 2001. Hydrophobic interaction chromatography of proteins. Journal of Biotechnology, 87:143–59.
-
(2001)
Journal of Biotechnology
, vol.87
, pp. 143-159
-
-
Queiroz, J.A.1
Tomaz, C.T.2
Cabral, J.M.3
-
101
-
-
0023710261
-
Large-scale isolation of covalently closed circular DNA using gel filtration chromatography
-
Raymond, G.J., Bryant, P. K., Nelson, A., and Johnson, J.D., 1988. Large-scale isolation of covalently closed circular DNA using gel filtration chromatography. Analytical Biochemistry, 173:125–33.
-
(1988)
Analytical Biochemistry
, vol.173
, pp. 125-133
-
-
Raymond, G.J.1
Bryant, P.K.2
Nelson, A.3
Johnson, J.D.4
-
102
-
-
14744282879
-
Gene medicines: The end of the beginning?
-
Rolland, A., 2005. Gene medicines:the end of the beginning?. Advanced Drug Delivery Reviews, 57:669–73.
-
(2005)
Advanced Drug Delivery Reviews
, vol.57
, pp. 669-673
-
-
Rolland, A.1
-
103
-
-
0038697491
-
Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen
-
Rosenberg, S.A., Yang, J. C., Sherry, R.M., 2003. Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen. Human Gene Therapy, 14:709–14.
-
(2003)
Human Gene Therapy
, vol.14
, pp. 709-714
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
104
-
-
10844293485
-
Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence
-
Rozkov, A., Avignone-Rossa, C.A., Ertl, P.F., 2004. Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence. Biotechnology and Bioengineering, 88:909–15.
-
(2004)
Biotechnology and Bioengineering
, vol.88
, pp. 909-915
-
-
Rozkov, A.1
Avignone-Rossa, C.A.2
Ertl, P.F.3
-
105
-
-
33646192500
-
Applications of silica supports in affinity chromatography
-
Schiel, J.E., Mallik, R., Soman, S., Joseph, K.S., and Hage, D.S., 2006. Applications of silica supports in affinity chromatography. Journal of Separation Science, 29:719–37.
-
(2006)
Journal of Separation Science
, vol.29
, pp. 719-737
-
-
Schiel, J.E.1
Mallik, R.2
Soman, S.3
Joseph, K.S.4
Hage, D.S.5
-
106
-
-
3042667834
-
Animal-free production of ccc-supercoiled plasmids for research and clinical applications
-
Schleef, M., and Schmidt, T., 2004. Animal-free production of ccc-supercoiled plasmids for research and clinical applications. Journal of Gene Medicine, 6:S45–53.
-
(2004)
Journal of Gene Medicine
, vol.6
, pp. S45-S53
-
-
Schleef, M.1
Schmidt, T.2
-
107
-
-
0032190243
-
Purification of plasmids by triplex affinity interaction
-
Schluep, T., and Cooney, C.L., 1998. Purification of plasmids by triplex affinity interaction. Nucleic Acids Research, 26:4524–8.
-
(1998)
Nucleic Acids Research
, vol.26
, pp. 4524-4528
-
-
Schluep, T.1
Cooney, C.L.2
-
108
-
-
85024157470
-
-
WO02/062987
-
Schmidt, T., Schleef, M., Friehs, K., and Flaschel, E., 2002. Method for producing homogeneus nucleic acid multimers for use in pharmaceutical compositions. WO02/062987
-
(2002)
Method for producing homogeneus nucleic acid multimers for use in pharmaceutical compositions
-
-
Schmidt, T.1
Schleef, M.2
Friehs, K.3
Flaschel, E.4
-
109
-
-
34247208149
-
Progress toward a nonviral gene therapy protocol for the treatment of anemia
-
Sebestyen, M.G., Hegge, J. O., Noble, M.A., 2007. Progress toward a nonviral gene therapy protocol for the treatment of anemia. Human Gene Therapy, 18:269–85.
-
(2007)
Human Gene Therapy
, vol.18
, pp. 269-285
-
-
Sebestyen, M.G.1
Hegge, J.O.2
Noble, M.A.3
-
110
-
-
0022407889
-
Effects of recombinant plasmid content on growth properties and cloned gene product formation in Escherichia coli
-
Seo, J.H., and Bailey, J.E., 1985. Effects of recombinant plasmid content on growth properties and cloned gene product formation in Escherichia coli. Biotechnology and Bioengineering, 27:1668–74.
-
(1985)
Biotechnology and Bioengineering
, vol.27
, pp. 1668-1674
-
-
Seo, J.H.1
Bailey, J.E.2
-
111
-
-
0038405322
-
Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA
-
Sheets, E.E., Urban, R. G., Crum, C.P., 2003. Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA. American Journal of Obstetrics and Gynecology, 188:916–26.
-
(2003)
American Journal of Obstetrics and Gynecology
, vol.188
, pp. 916-926
-
-
Sheets, E.E.1
Urban, R.G.2
Crum, C.P.3
-
112
-
-
63049124317
-
DNA plasmid production in different host strains of Escherichia coli
-
Singer, A., Eiteman, M.A., and Altman, E., 2009. DNA plasmid production in different host strains of Escherichia coli. Journal of Industrial Microbiology and Biotechnology, 36:521–30.
-
(2009)
Journal of Industrial Microbiology and Biotechnology
, vol.36
, pp. 521-530
-
-
Singer, A.1
Eiteman, M.A.2
Altman, E.3
-
114
-
-
69749128313
-
Histidine affinity chromatography of homo-oligonucleotides. Role of multiple interactions on retention
-
Sousa, A., Sousa, F., Prazeres, D.M.F., and Queiroz, J.A., 2009a. Histidine affinity chromatography of homo-oligonucleotides. Role of multiple interactions on retention. Biomedical Chromatography, 23:745–53.
-
(2009)
Biomedical Chromatography
, vol.23
, pp. 745-753
-
-
Sousa, A.1
Sousa, F.2
Prazeres, D.M.F.3
Queiroz, J.A.4
-
115
-
-
67650001336
-
Selectivity of arginine chromatography in promoting different interactions using synthetic oligonucleotides as model
-
Sousa, A., Sousa, F., and Queiroz, J.A., 2009b. Selectivity of arginine chromatography in promoting different interactions using synthetic oligonucleotides as model. Journal of Separation Science, 32:1665–72.
-
(2009)
Journal of Separation Science
, vol.32
, pp. 1665-1672
-
-
Sousa, A.1
Sousa, F.2
Queiroz, J.A.3
-
116
-
-
22144443546
-
Separation of supercoiled and open circular plasmid DNA isoforms by chromatography with a histidine-agarose support
-
Sousa, F., Tomaz, C. T., Prazeres, D.M.F., and Queiroz, J.A., 2005. Separation of supercoiled and open circular plasmid DNA isoforms by chromatography with a histidine-agarose support. Analytical Biochemistry, 343:183–5.
-
(2005)
Analytical Biochemistry
, vol.343
, pp. 183-185
-
-
Sousa, F.1
Tomaz, C.T.2
Prazeres, D.M.F.3
Queiroz, J.A.4
-
117
-
-
33750607427
-
Selective purification of supercoiled plasmid DNA from clarified cell lysates with a single histidine-agarose chromatography step
-
Sousa, F., Freitas, S., Azzoni, A. R., Prazeres, D.M.F., and Queiroz, J.A., 2006. Selective purification of supercoiled plasmid DNA from clarified cell lysates with a single histidine-agarose chromatography step. Biotechnology and Applied Biochemistry, 45:131–40.
-
(2006)
Biotechnology and Applied Biochemistry
, vol.45
, pp. 131-140
-
-
Sousa, F.1
Freitas, S.2
Azzoni, A.R.3
Prazeres, D.M.F.4
Queiroz, J.A.5
-
118
-
-
35748978569
-
Circular dichroism investigation of the effect of plasmid DNA structure on retention in histidine chromatography
-
Sousa, F., Prazeres, D.M.F., and Queiroz, J.A., 2007. Circular dichroism investigation of the effect of plasmid DNA structure on retention in histidine chromatography. Archives of Biochemistry and Biophysics, 467:154–62.
-
(2007)
Archives of Biochemistry and Biophysics
, vol.467
, pp. 154-162
-
-
Sousa, F.1
Prazeres, D.M.F.2
Queiroz, J.A.3
-
119
-
-
39149129979
-
Specific recognition of supercoiled plasmid DNA in arginine affinity chromatography
-
Sousa, F., Matos, T., Prazeres, D.M.F., and Queiroz, J.A., 2008a. Specific recognition of supercoiled plasmid DNA in arginine affinity chromatography. Analytical Biochemistry, 374:432–4.
-
(2008)
Analytical Biochemistry
, vol.374
, pp. 432-434
-
-
Sousa, F.1
Matos, T.2
Prazeres, D.M.F.3
Queiroz, J.A.4
-
120
-
-
48849111296
-
Affinity chromatography approaches to overcome the challenges of purifying plasmid DNA
-
Sousa, F., Prazeres, D.M.F., and Queiroz, J.A., 2008b. Affinity chromatography approaches to overcome the challenges of purifying plasmid DNA. Trends in Biotechnology, 26:518–25.
-
(2008)
Trends in Biotechnology
, vol.26
, pp. 518-525
-
-
Sousa, F.1
Prazeres, D.M.F.2
Queiroz, J.A.3
-
121
-
-
61349098946
-
Binding and elution strategy for improved performance of arginine affinity chromatography in supercoiled plasmid DNA purification
-
Sousa, F., Prazeres, D.M.F., and Queiroz, J.A., 2008c. Binding and elution strategy for improved performance of arginine affinity chromatography in supercoiled plasmid DNA purification. Biomedical Chromatography, 23:160–5.
-
(2008)
Biomedical Chromatography
, vol.23
, pp. 160-165
-
-
Sousa, F.1
Prazeres, D.M.F.2
Queiroz, J.A.3
-
122
-
-
59449090459
-
Improvement of transfection efficiency by using supercoiled plasmid DNA purified with arginine affinity chromatography
-
Sousa, F., Prazeres, D.M.F., and Queiroz, J.A., 2009c. Improvement of transfection efficiency by using supercoiled plasmid DNA purified with arginine affinity chromatography. Journal of Gene Medicine, 11:79–88.
-
(2009)
Journal of Gene Medicine
, vol.11
, pp. 79-88
-
-
Sousa, F.1
Prazeres, D.M.F.2
Queiroz, J.A.3
-
123
-
-
4644359883
-
Plasmid DNA purification
-
Stadler, J., Lemmens, R., and Nyhammar, T., 2004. Plasmid DNA purification. Journal of Gene Medicine, 6:S54–66.
-
(2004)
Journal of Gene Medicine
, vol.6
, pp. S54-S66
-
-
Stadler, J.1
Lemmens, R.2
Nyhammar, T.3
-
124
-
-
30444444679
-
Development of effective vaccines against pandemic influenza
-
Subbarao, K., Murphy, B.R., and Fauci, A.S., 2006. Development of effective vaccines against pandemic influenza. Immunity, 24:5–9.
-
(2006)
Immunity
, vol.24
, pp. 5-9
-
-
Subbarao, K.1
Murphy, B.R.2
Fauci, A.S.3
-
125
-
-
33846241366
-
Differential interactions of plasmid DNA, RNA and endotoxin with immobilised and free metal ions
-
Tan, L., Lai, W. B., Lee, C. T., Kim, D.S., and Choe, W.S., 2007. Differential interactions of plasmid DNA, RNA and endotoxin with immobilised and free metal ions. Journal of Chromatography A, 1141:226–34.
-
(2007)
Journal of Chromatography A
, vol.1141
, pp. 226-234
-
-
Tan, L.1
Lai, W.B.2
Lee, C.T.3
Kim, D.S.4
Choe, W.S.5
-
126
-
-
33746901204
-
Non-viral in vivo immune gene therapy of cancer: Combined strategies for treatment of systemic disease
-
Tangney, M., Casey, G., Larkin, J.O., 2006. Non-viral in vivo immune gene therapy of cancer:combined strategies for treatment of systemic disease. Cancer Immunology Immunotherapy, 55:1443–50.
-
(2006)
Cancer Immunology Immunotherapy
, vol.55
, pp. 1443-1450
-
-
Tangney, M.1
Casey, G.2
Larkin, J.O.3
-
127
-
-
0037424580
-
Adsorptive membrane chromatography for purification of plasmid DNA
-
Teeters, M.A., Conrardy, S. E., Thomas, B. L., Root, T.W., and Lightfoot, E.N., 2003. Adsorptive membrane chromatography for purification of plasmid DNA. Journal of Chromatography A, 989:165–73.
-
(2003)
Journal of Chromatography A
, vol.989
, pp. 165-173
-
-
Teeters, M.A.1
Conrardy, S.E.2
Thomas, B.L.3
Root, T.W.4
Lightfoot, E.N.5
-
128
-
-
58149122980
-
Upstream processing of plasmid DNA for vaccine and gene therapy applications
-
Tejeda-Mansir, A., and Montesinos, R.M., 2008. Upstream processing of plasmid DNA for vaccine and gene therapy applications. Recent Patents on Biotechnology, 2:156–72.
-
(2008)
Recent Patents on Biotechnology
, vol.2
, pp. 156-172
-
-
Tejeda-Mansir, A.1
Montesinos, R.M.2
-
129
-
-
0013692898
-
-
WO 97/29190
-
Thatcher, D.R., Hitchcock, A. G., Hanak, J.A., and Varley, D., 1997. Method of plasmid DNA production and purification patent. WO 97/29190
-
(1997)
Method of plasmid DNA production and purification patent
-
-
Thatcher, D.R.1
Hitchcock, A.G.2
Hanak, J.A.3
Varley, D.4
-
130
-
-
0035543883
-
Design of expanded bed supports for the recovery of plasmid DNA by anion exchange adsorption
-
Theodossiou, I., Sondergaard, M., and Thomas, O.R., 2001. Design of expanded bed supports for the recovery of plasmid DNA by anion exchange adsorption. Bioseparation, 10:31–44.
-
(2001)
Bioseparation
, vol.10
, pp. 31-44
-
-
Theodossiou, I.1
Sondergaard, M.2
Thomas, O.R.3
-
131
-
-
0037144158
-
DNA-induced inter-particle cross-linking during expanded bed adsorption chromatography. Impact on future support design
-
Theodossiou, I., and Thomas, O.R., 2002. DNA-induced inter-particle cross-linking during expanded bed adsorption chromatography. Impact on future support design. Journal of Chromatography A, 971:73–86.
-
(2002)
Journal of Chromatography A
, vol.971
, pp. 73-86
-
-
Theodossiou, I.1
Thomas, O.R.2
-
132
-
-
0037059590
-
Impact of the physical and topographical characteristics of adsorbent solid-phases upon the fluidised bed recovery of plasmid DNA from Escherichia coli lysates
-
Thwaites, E., Burton, S.C., and Lyddiatt, A., 2002. Impact of the physical and topographical characteristics of adsorbent solid-phases upon the fluidised bed recovery of plasmid DNA from Escherichia coli lysates. Journal of Chromatography A, 943:77–90.
-
(2002)
Journal of Chromatography A
, vol.943
, pp. 77-90
-
-
Thwaites, E.1
Burton, S.C.2
Lyddiatt, A.3
-
133
-
-
34447345938
-
Plasmid adsorption to anion-exchange matrices: Comments on plasmid recovery
-
Tiainen, P., Galaev, I., and Larsson, P.O., 2007a. Plasmid adsorption to anion-exchange matrices:Comments on plasmid recovery. Biotechnology Journal, 2:726–35.
-
(2007)
Biotechnology Journal
, vol.2
, pp. 726-735
-
-
Tiainen, P.1
Galaev, I.2
Larsson, P.O.3
-
134
-
-
33845426368
-
Superporous agarose anion exchangers for plasmid isolation
-
Tiainen, P., Gustavsson, P. E., Ljunglof, A., and Larsson, P.O., 2007b. Superporous agarose anion exchangers for plasmid isolation. Journal of Chromatography A, 1138:84–94.
-
(2007)
Journal of Chromatography A
, vol.1138
, pp. 84-94
-
-
Tiainen, P.1
Gustavsson, P.E.2
Ljunglof, A.3
Larsson, P.O.4
-
135
-
-
34247190615
-
Plasmid purification using non-porous anion-exchange silica fibres
-
Tiainen, P., Gustavsson, P. E., Mansson, M.O., and Larsson, P.O., 2007c. Plasmid purification using non-porous anion-exchange silica fibres. Journal of Chromatography A, 1149:158–68.
-
(2007)
Journal of Chromatography A
, vol.1149
, pp. 158-168
-
-
Tiainen, P.1
Gustavsson, P.E.2
Mansson, M.O.3
Larsson, P.O.4
-
136
-
-
0034681043
-
DNA adsorption onto polyethylenimine-attached poly(p-chloromethylstyrene) beads
-
Unsal, E., Bahar, T., Tuncel, M., and Tuncel, A., 2000. DNA adsorption onto polyethylenimine-attached poly(p-chloromethylstyrene) beads. Journal of Chromatography A, 898:167–77.
-
(2000)
Journal of Chromatography A
, vol.898
, pp. 167-177
-
-
Unsal, E.1
Bahar, T.2
Tuncel, M.3
Tuncel, A.4
-
137
-
-
13844254962
-
Application of monoliths for plasmid DNA purification development and transfer to production
-
Urthaler, J., Schlegl, R., Podgornik, A., 2005. Application of monoliths for plasmid DNA purification development and transfer to production. Journal of Chromatography A, 1065:93–106.
-
(2005)
Journal of Chromatography A
, vol.1065
, pp. 93-106
-
-
Urthaler, J.1
Schlegl, R.2
Podgornik, A.3
-
138
-
-
0022016460
-
Rapid large-scale purification of plasmid DNA by medium or low pressure gel filtration. Application: Construction of thermoamplifiable expression vectors
-
Vo-Quang, T., Malpiece, Y., Buffard, D., 1985. Rapid large-scale purification of plasmid DNA by medium or low pressure gel filtration. Application:construction of thermoamplifiable expression vectors. Bioscience Reports, 5:101–11.
-
(1985)
Bioscience Reports
, vol.5
, pp. 101-111
-
-
Vo-Quang, T.1
Malpiece, Y.2
Buffard, D.3
-
139
-
-
0032538597
-
Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
-
Wang, R., Doolan, D. L., Le, T.P., 1998. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science, 282:476–80.
-
(1998)
Science
, vol.282
, pp. 476-480
-
-
Wang, R.1
Doolan, D.L.2
Le, T.P.3
-
140
-
-
37349109250
-
Plasmid DNA- and messenger RNA-based anti-cancer vaccination
-
Weide, B., Garbe, C., Rammensee, H.G., and Pascolo, S., 2008. Plasmid DNA- and messenger RNA-based anti-cancer vaccination. Immunology Letters, 115:33–42.
-
(2008)
Immunology Letters
, vol.115
, pp. 33-42
-
-
Weide, B.1
Garbe, C.2
Rammensee, H.G.3
Pascolo, S.4
-
141
-
-
0028991824
-
Bacterial lipopolysaccharide copurifies with plasmid DNA: Implications for animal models and human gene therapy
-
Wicks, I.P., Howell, M. L., Hancock, T., 1995. Bacterial lipopolysaccharide copurifies with plasmid DNA:implications for animal models and human gene therapy. Human Gene Therapy, 6:317–23.
-
(1995)
Human Gene Therapy
, vol.6
, pp. 317-323
-
-
Wicks, I.P.1
Howell, M.L.2
Hancock, T.3
-
142
-
-
0030979103
-
Efficient purification of plasmid DNA for gene transfer using triple-helix affinity chromatography
-
Wils, P., Escriou, V., Warnery, A., 1997. Efficient purification of plasmid DNA for gene transfer using triple-helix affinity chromatography. Gene Therapy, 4:323–30.
-
(1997)
Gene Therapy
, vol.4
, pp. 323-330
-
-
Wils, P.1
Escriou, V.2
Warnery, A.3
-
143
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff, J.A., Malone, R. W., Williams, P., 1990. Direct gene transfer into mouse muscle in vivo. Science, 247:1465–8.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
-
144
-
-
0037143805
-
Protein-mediated isolation of plasmid DNA by a zinc finger-glutathione S-transferase affinity linker
-
Woodgate, J., Palfrey, D., Nagel, D. A., Hine, A.V., and Slater, N.K., 2002. Protein-mediated isolation of plasmid DNA by a zinc finger-glutathione S-transferase affinity linker. Biotechnology and Bioengineering, 79:450–6.
-
(2002)
Biotechnology and Bioengineering
, vol.79
, pp. 450-456
-
-
Woodgate, J.1
Palfrey, D.2
Nagel, D.A.3
Hine, A.V.4
Slater, N.K.5
-
145
-
-
34250767811
-
Generalizing a two-conformation model for describing salt and temperature effects on protein retention and stability in hydrophobic interaction chromatography
-
Xiao, Y., Rathore, A., O'Connell, J.P., and Fernandez, E.J., 2007. Generalizing a two-conformation model for describing salt and temperature effects on protein retention and stability in hydrophobic interaction chromatography. Journal of Chromatography A, 1157:197–206.
-
(2007)
Journal of Chromatography A
, vol.1157
, pp. 197-206
-
-
Xiao, Y.1
Rathore, A.2
O'Connell, J.P.3
Fernandez, E.J.4
-
146
-
-
19144365781
-
Effects of medium composition on the production of plasmid DNA vector potentially for human gene therapy
-
Xu, Z.N., Shen, W. H., Chen, H., and Cen, P.L., 2005. Effects of medium composition on the production of plasmid DNA vector potentially for human gene therapy. Journal of Zhejiang University Science B, 6:396–400.
-
(2005)
Journal of Zhejiang University Science B
, vol.6
, pp. 396-400
-
-
Xu, Z.N.1
Shen, W.H.2
Chen, H.3
Cen, P.L.4
-
147
-
-
53549102227
-
Host strain influences on supercoiled plasmid DNA production in Escherichia coli: Implications for efficient design of large-scale processes
-
Yau, S.Y., Keshavarz-Moore, E., and Ward, J., 2008. Host strain influences on supercoiled plasmid DNA production in Escherichia coli:Implications for efficient design of large-scale processes. Biotechnology and Bioengineering, 101:529–44.
-
(2008)
Biotechnology and Bioengineering
, vol.101
, pp. 529-544
-
-
Yau, S.Y.1
Keshavarz-Moore, E.2
Ward, J.3
-
148
-
-
34248512408
-
The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model
-
Yonenaga, Y., Mori, A., Fujimoto, A., 2007. The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model. Journal of Gene Medicine, 9:299–307.
-
(2007)
Journal of Gene Medicine
, vol.9
, pp. 299-307
-
-
Yonenaga, Y.1
Mori, A.2
Fujimoto, A.3
-
149
-
-
34447321575
-
A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis
-
Zanin, M.P., Webster, D.E., and Wesselingh, S.L., 2007. A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis. Journal of Neurovirology, 13:284–9.
-
(2007)
Journal of Neurovirology
, vol.13
, pp. 284-289
-
-
Zanin, M.P.1
Webster, D.E.2
Wesselingh, S.L.3
-
150
-
-
22544464723
-
A continuous thermal lysis procedure for the large-scale preparation of plasmid DNA
-
Zhu, K., Jin, H., Ma, Y., 2005. A continuous thermal lysis procedure for the large-scale preparation of plasmid DNA. Journal of Biotechnology, 118:257–64.
-
(2005)
Journal of Biotechnology
, vol.118
, pp. 257-264
-
-
Zhu, K.1
Jin, H.2
Ma, Y.3
|