Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies

Vaccine

Volumn 25, Issue 27, 2007, Pages 5013-5024

  Przybylowski, Mark ^a   Bartido, Shirley ^a   Borquez Ojeda, Oriana ^a   Sadelain, Michel ^a   Rivière, Isabelle ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

cGMP; Clinical grade plasmid DNA; Gene therapy

Indexed keywords

2 PROPANOL; ENDOTOXIN; GENOMIC DNA; PLASMID DNA; PROTEIN; RNA;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BACTERIAL CELL; BIOMASS; CENTRIFUGATION; CONTROLLED STUDY; DNA ISOLATION; DRUG POTENCY; DRUG SCREENING; FERMENTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRECIPITATION; PRIORITY JOURNAL; RESTRICTION MAPPING; VACCINE PRODUCTION;

ANIMALS; CELLULOSE; CHROMATOGRAPHY, ION EXCHANGE; CHROMOSOME MAPPING; CLINICAL TRIALS, PHASE I; CULTURE MEDIA; DNA; DRUG INDUSTRY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FERMENTATION; HUMANS; INDICATORS AND REAGENTS; PLASMIDS; VACCINES, DNA;

EID: 34249942373     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.04.077     Document Type: Article

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