The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model

Journal of Gene Medicine

Volumn 9, Issue 4, 2007, Pages 299-307

  Yonenaga, Yoshikuni ^a   Mori, Akira ^a   Fujimoto, Akihisa ^a   Nagayama, Satoshi ^a   Tachibana, Tsuyoshi ^a   Onodera, Hisashi ^a   Uemoto, Shinji ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hydrodynamics based procedure; Liver metastasis; Naked plasmid DNA; Natural killer cell; Unmethylated CpG motif

Indexed keywords

GADOLINIUM CHLORIDE; GANGLIOTETRAOSYLCERAMIDE; METHYLTRANSFERASE; NAKED DNA; PLASMID DNA; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GENE THERAPY; CELL ACTIVATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; HYDRODYNAMICS BASED TRANSFECTION; IMMUNOCOMPETENCE; IMMUNOSTIMULATION; INNATE IMMUNITY; INOCULATION; KUPFFER CELL; LIVER METASTASIS; MALE; METASTASIS INHIBITION; MONONUCLEAR CELL; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF;

ANIMALS; CELL LINE, TUMOR; CYTOTOXICITY TESTS, IMMUNOLOGIC; DNA; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNITY, NATURAL; INTERFERON TYPE II; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASM METASTASIS; PLASMIDS;

MURINAE; MUS;

EID: 34248512408     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1013     Document Type: Article

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