Ultra scale-down studies of the effect of flow and impact conditions during E. coli cell processing

Biotechnology and Bioengineering

Volumn 95, Issue 4, 2006, Pages 671-683

  Chan, G ^a   Booth, A J ^a   Mannweiler, K ^b   Hoare, M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GEA Westfalia Separator ^*  (Germany)

Author keywords

Cell breakage; E. coli; Shear sensitive material; Ultra scale down

Indexed keywords

BIOLOGICAL MEMBRANES; CELL CULTURE; CONTAMINATION; FERMENTATION; PURIFICATION;

CELL BREAKAGE; IMPACT VELOCITY; SHEAR-SENSITIVE MATERIAL; ULTRA SCALE-DOWN;

ESCHERICHIA COLI;

ARTICLE; CAPILLARY FLOW; CELL DAMAGE; CELL DISRUPTION; CENTRIFUGATION; CONTAMINATION; ESCHERICHIA COLI; FERMENTATION; FILTRATION; FLOW MEASUREMENT; METHODOLOGY; NONHUMAN; PROCESSING; PURIFICATION; SHEAR RATE;

BIOREACTORS; CAPILLARITY; CELL PHYSIOLOGY; ESCHERICHIA COLI; MICROSCOPY, ELECTRON, TRANSMISSION; RHEOLOGY; STRESS, MECHANICAL; VISCOSITY;

ESCHERICHIA COLI;

EID: 33750574751     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21049     Document Type: Article

References (63)

1. Abu-Reesh I, Kargi F. 1989. Biological responses of hybridoma cells to defined hydrodynamic shear stress. J Biotechnol 9:167-178.
2. Aloi LE, Cherry RS. 1995. Cellular response to agitation characterized by energy dissipation at the impeller tip. Chem Eng Sci 51:1523-1529.
3. Arnaud JP, Lacroix C, Foussereau C, Chopin L. 1993. Shear stress effects on growth and activity of Lactobacillus delbrueckii subsp Bulgaricus. J Biotechnol 29:157-175.
4. Bell DJ, Dunnill P. 1982. Shear disruption of soya protein precipitate particles and the effect of aging in a stirred tank. Biotech Bioeng 24: 1271-1285.
5. Bobrowicz G. 1999. The compliance costs of hasty process development. Biopharm Aug 12:35-58.
6. Born C, Zhang Z, Al-Rubeai M, Thomas CR. 1992. Estimation of disruption of animal cells by laminar shear stress. Biotech Bioeng 40:1004-1010.
7. Boychyn M, Yim SSS, Shamlou P, Bulmer M, More J, Hoare M. 2001. Characterisation of flow intensity in continuous centrifuges for the development of laboratory mimics. Chem Eng Sci 56:1-12.
8. Boychyn M, Yim SSS, Bulmer M, More J, Bracewell DG, Hoare M. 2004. Performance prediction of industrial centrifuges using scale-down models. Bioprocess Biosyst Eng 26:385-391.
9. Carlson A, Signs M, Lierman L, Boor R, Jim Jem K. 1995. Mechanical disruption of Escherichia Coli for plasmid recovery. Biotech Bioeng 48: 303-315.
10. Chalmers JJ, Bavarian F. 1991. Microscopic visualisation of insect cell-bubble interactions. II: The bubble film and bubble rupture. Biotechnol Prog 7:151-158.
11. Cherry RS, Hulle CT. 1992. Cell death in the thin films of bursting bubbles. Biotechnol Prog 8:11-18.
12. Cherry RS, Know KJ. 1990. Transient shear stresses on a suspension cell in turbulence. Biotech Bioeng 36:563-571.
13. Cherry RS, Papoutsakis ET. 1986. Hydrodynamic effects on cells in agitated tissue culture reactors. Bioprocess Eng 1:29-41.
14. Cherry RS, Papoutsakis ET. 1988. Physical mechanisms of cell damage in microcarrier cell culture bioreactors. Biotech Bioeng 32:1001-1014.
15. Chisti Y. 2000. Animal-cell damage in sparged bioreactors. Trends in Biotechnol 18:420-432.
16. Croughan MS, Hamel JF, Wang DIC. 1987. Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotech Bioeng 29:130-141.
17. Croughan MS, Sayre ES, Wang DIC. 1989. Viscous reduction of turbulent damage in animal cell cultures. Biotech Bioeng 33:862-972.
18. Davies TW, Metcalfe RA, Jackson MK. 1980. The anatomy and impact characteristics of large scale water jets. Fifth international symposium on jet cutting technology. 15-21.
19. Edwards N, Beeton S, Bull AT, Merchuk JC. 1989. A novel device for the assessment of shear effects on suspended microbial cultures. Appl Microbiol Biotechnol 30:190-195.
20. Fox RW, McDonald AT. 1994. Introduction to fluid mechanics, 4th edition. New York: John Wiley and Sons, Inc. 330-333.
21. Frangos JA, Mc Entire LV, Eskin SG. 1988. Shear stress induced stimulation of mammalian cell metabolism. Biotech Bioeng 32:1053-1060.
22. Garcia-Briones MA, Chalmers JJ. 1994. Flow parameters associated with hydrodynamic cell injury. Biotech Bioeng 44:1089-1098.
23. Gray PP, Dunnill P, Lilly MD. 1972. The continuous-flow isolation of enzymes. In: Terui G, editor. Ferment. Technol. Today, Tokyo: Soc of Ferment Technol. 347-351.
24. Haller KK, Ventikos Y, Poulikakos D, Monkewitz P. 2002. Computational study of high-speed liquid droplet impact. J Appl Phys 92:2821-2828.
25. Handa A, Emery AN, Spier RE. 1987. On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors. Dev Biol Stand 66:241-253.
26. Hashish M, Reichman JM. 1980. Analysis of waterjet cutting at high traverse rates. Fifth international symposium on jet cutting technology. 57-74.
27. Hrycak P, Lee D, Gauntner J, Livingood J. 1969. Experimental flow characteristics of a single turbulent jet impinging on a flat plate. Lewis research center, NASA, Cleveland, Ohio. 720-03:1-32.
28. Kawase Y, Moo-Young M. 1990. Mathematical models for design of bioreactors: Applications of Kolmogoroff's theory of isotropic turbulence. Chem Eng Sci 43:19-41.
29. Keshavarz Moore E, Hoare M, Dunnill P. 1990. Disruption of bakers yeast in a high-pressure homogenizer: New evidence on mechanism. Enzyme Microb Technol 12:764-770.
30. Kretzmer G, Schugerl K. 1991. Response of mammalian cells to shear stress. Applied Microbiol Biotechnol 34:613-616.
31. Lange H, Taillandier P, Riba JP. 2001. Effect of high shear stress on microbial viability. J Chem Technol Biotechnol 76:501-505.
32. Lesser MB, Field JE. 1983. The geometric wave theory of liquid impact, sixth conference on erosion by liquid and solid impact, Cavendish laboratory, Madingley road, Cambridge, CB3 OHE, UK.
33. Levesque MJ, Sprague EA, Schwartz CJ, Nerem RM. 1989. The influence of shear stress on cultured vascular endothelial cells: The stress response of an anchorage dependent mammalian cell. Biotechnol Prog 5:1-8.
34. Levy MS, Collins IJ, Yim SS, War JM, Titchener-Hooker N, Shamlou P, Dunnill P. 1999. Effect of shear on plasmid DNA in solution. Bioprocess Eng 20:7-13.
35. Maa YF, Chung CH. 1996. Effect of high shear on proteins. Biotech Bioeng 51:458-465.
36. Maguire LA, Zhang H, Shamlou PA. 2003. Preparation of small unilamellar vesicles (SUV) and biophysical characterization of their complexes with poly-L-lysine-condensed plasmid DNA. Biotechnol Appl Biochem 37: 73-81.
37. Mannweiler K, Hoare M. 1992. The scale-down of an industrial disc-stack centrifuge. Bioprocess Eng 8:19-25.
38. McQueen A, Bailey JE. 1989. Influence of serum level, cell line, flow type and viscosity on flow-induced lysis of suspended mammalian cells. Biotechnol Lett 11:531-536.
39. McQueen A, Meilhoc E, Bailey JE. 1987. Flow effects on the viability and lysis of suspended mammalian cells. Biotechnol Lett 9:831-836.
40. Mosqueira FG, Higgins JJ, Dunnill P, Lilly MD. 1981. Characteristics of mechanically disrupted bakers yeast in relation to its separation in industrial centrifuges. Biotech Bioeng 23:335-343.
41. Neal G, Christie J, Keshavarz-Moore E, Ayazi Shamlou P. 2003. Ultra scale-down approach for the prediction of full-scale recovery of ovine polycolonal immunoglobulins used in the manufacture of snake venom-specific Fab fragments. Biotech Bioeng 81:149-157.
42. Obara T, Bourne NK, Field JE. 1995. Liquid-jet impact on liquid and solid surfaces. WEAR 186-187:388-394.
43. Oh SKW, Nienow AW, Al-Rubeai M, Emery AN. 1989. The effects of agitation intensity with and without continuous sparging on the growth and antibody production of hybridoma cells. J Biotechnol 12:45-62.
44. Olive GE. 1959. Ps in metals caused by collision with liquid drops and soft metal spheres. J Res Nat Bureau Stand 62:229-246.
45. Papoutsakis ET. 1991. Fluid-mechanical damage of animal cells in bioreactors. Trends Biotechnol 9:427-437.
46. Peterson JF, McIntire LV, Papoutsakis ET. 1988. Shear sensitivity of cultured hybridoma cells (CRL-8018) depends on mode growth, culture age and metabolic concentration. J Biotechnol 7:229-246.
47. Reichman JM, Cheung JB. 1980. Research and development of a high-pressure waterjet device for geothermal exploration and drilling. Fifth international symposium on jet cutting technology. 181-200.
48. Schmid-Schönbein H, Wells R. 1969. Fluid drop-like transition of erythrocytes under shear. Science 165:288-291.
49. Shamlou PA, Stavrinides S, Titchener-Hooker N, Hoare M. 1994. Growth-independent breakage frequency of protein precipitates in turbulently agitated bioreactors. Chem Eng Sci 49:2647-2656.
50. Shamlou PA, Siddiqi SF, Titchener-Hooker NJ. 1995. A physical model of high-pressure disruption of bakers yeast cells. Chem Eng Sci 50:1383-1391.
51. Shamlou PA, Gierczycki AT, Titchener-Hooker N. 1996. Breakage of floes in liquid suspension agitated by vibrating and rotating mixers. Chem Eng Sci 62:23-34.
52. Shavlovsky DS. 1972. Hydrodynamics of high pressure fine continuous jets. First International symposium on jet cutting technology. A6-A81.
53. Smith FT, Li L, Wu GX. 2003. Air cushioning with a lubrication/inviscid balance. J Fluid Mech 482:291-318.
54. Stathopoulos NA, Hellums JD. 1985. Shear stress effects on human embryonic kidney cells. In vitro. Biotech Bioeng 27:1021-1026.
55. Summers D. 1995. Water jetting technology. London: E&FN SPON pp 82.
56. Vickers GW, Harrison PW, Houlson R. 1980. Extending the range of cavitation cleaning jets. Fifth international symposium on jet cutting technology. 403-412.
57. Wase DAJ, Patel YR. 1985. Variations in volumes of microbial cells with change in the agitation rates of chemostat cultures. J Gen Microbiol 131:725-736.
58. Welty JR, Wicks CE, Wilson RE. 1984. Fundamentals of momentum, heat, and mass transfer, 3rd edition. New York: John Wiley and Sons. 202-209.
59. Wu J, King G, Daugulis AJ, Faulkner P, Bone DH, Goosen MFA. 1990. Adaptation of insect cells to suspension culture. J Ferment Bioeng 70:90-93.
60. Yanaida K. 1974. How characteristics of water jets. Second international symposium on jet cutting technology. A2-A19.
61. Yanaida K, Ohashi A. 1978. Flow characteristics of water jets. Fourth international symposium on jet cutting technology. A3-A39.
62. Yim SS, Shamlou PA. 2000. The engineering effects of fluids flow on freely suspended biological macro-materials and macromolecules. Adv Biochem Eng Biotechnol 67:85-121.
63. Zhang Z, Al-Rubeai M, Thomas CR. 1993. Estimation of disruption of animal cells by turbulent capillary flow. Biotech Bioeng 42:987-993.