DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice

Journal of Virology

Volumn 73, Issue 3, 1999, Pages 2094-2098

  Kodihalli, Shantha ^a   Goto, Hideo ^b   Kobasa, Darwyn L ^a   Krauss, Scott ^a   Kawaoka, Yoshihiro ^b   Webster, Robert G ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; HEMAGGLUTININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; GLYCOSYLATION; IMMUNE RESPONSE; IMMUNITY; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA GENE; VIRUS INACTIVATION; VIRUS INFECTION; VIRUS ISOLATION;

EID: 0033055999     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.3.2094-2098.1999     Document Type: Article

References (32)

1. Beare, A. S., and R. G. Webster. 1990. Replication of avian viruses in humans. Arch. Virol. 119:37-42.
2. Brown, E. G. 1990. Increased virulence of a mouse-adapted variant of influenza A/FM/1/47 virus is controlled by mutations in genome segments 4, 5, 7, and 8. J. Virol. 64:4523-4533.
3. Centers for Disease Control and Prevention. 1998. Update: isolation of avian influenza A(H5N1) viruses for humans - Hong Kong, 1997-1998. Morbid. Mortal. Weekly Rep. 46:1245-1247.
4. Claas, E. C., A. D. M. E. Osterhaus, R. van Beck, J. C. De Jong, G. F. Rimmelzwaan, D. A. Senne, S. Krauss, K. F. Shortridge, and R. G. Webster. 1998. Human influenza A(H5N1) virus related to a highly pathogenic avian influenza virus. Lancet 351:472-477.
5. Cohen, J. 1997. The flu pandemic that might have been. Science 277:1600-1601.
6. De Jong, J. C., E. C. Class, A. D. M. E. Osterhaus, R. G. Webster, and W. L. Lim. 1997. A pandemic warning? Nature 389:554. (Letter.)
7. Donnelly, J. J., A. Friedman, D. Martinez, D. L. Montgomery, J. W. Shiver, S. H. Motzel, J. B. Ulmer, and M. A. Liu. 1995. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against anligenic drift in influenza virus. Nat. Med. 6:583-587.
8. Eisenbraun, M. D., D. H. Fuller, and J. R. Haynes. 1993. Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization. DNA Cell Biol. 12:791-797.
9. Fynan, E. F., H. L. Robinson, and R. G. Webster. 1993. Use of DNA encoding influenza hemagglutinin as an avian influenza vaccine. DNA Cell Biol. 12:785-789.
10. Fynan, E. F., R. G. Webster, D. H. Fuller, J. R. Haynes, J. C. Santoro, and H. L. Robinson. 1993. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. USA 90: 11478-11482.
11. Gerhard, W. 1978. The analysis of the monoclonal immune response to influenza virus. III. The relationship between stimulation of virus primed precursor B-cells by heterotogous virus and reactivity of selected antibodies. J. Immunol. 120:1164-1168.
12. Gerhard, W., K. Mozdzanowska, M. Furchner, G. Washko, and K. Maiese. 1997. Role of the B-cell response in recovery of mice from primary influenza virus infection. Immunol Rev. 159:95-103.
13. Hartley, J. W., T. N. Fredrickson, R. A. Yetter, M. Makino, and H. C. Morse III. 1989. Retrovirus-induced murine acquired immunodeficiency syndrome: natural history of infection and differing susceptibility of inbred mouse strains. J. Virol. 63:1223-1231.
14. Hayden, F. G. 1997. Antivirals for pandemic influenza. J. Infect. Dis. 176(Suppl. 1):s56-s61.
15. Huygen, K., J. Content, O. Denis, D. L. Montgomery, A. M. Yawman, R. R. Deck, C. M. DeWitt, I. M. Orme, S. Baldwin, C. D'Souze, A. Dowart, E. Lozes, P. Vandenbussche, J.-P. Van Vooren, M. A. Liu, and J. B. Ulmer. 1996. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat. Med. 2:893-898.
16. Justewicz. D. M., P. C. Doherty, and R. G. Webster. 1995. The B-cell response in lymphoid tissue of mice immunized with various antigenic forms of the influenza virus hemagglutinin. J. Virol. 69:5414-5421.
17. Kawaoka, Y., and R. G. Webster. 1988. Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells. Proc. Natl. Acad. Sci. USA 85:324-328.
18. Kodihalli, S., J. R. Haynes, H. L. Robinson, and R. G. Webster. 1997. Cross-protection among lethal H5N2 influenza viruses induced by DNA vaccine to the hemagglutinin. J. Virol. 71:3391-3396.
19. Lee, A. H., Y. S. Suh, J. H. Sung, S. H. Yang, and Y. C. Sung. 1997. Comparison of various expression plasmids for the induction of immune response by DNA immunization. Mol. Cells 7(4):495-501.
20. Pertmer, T. M., M. D. Eisenbraun, D. McCabe, S. K. Prayaga, D. H. Fuller, and J. R. Haynes. 1995. Gene-gun based nucleic acid immunization: elicitation of humoral and cytotoxic responses following epidermal delivery of nanogram quantities of DNA. Vaccine 13:1427-1430.
21. Robinson, H. L., D. M. Feltquate, M. J. Morin, J. R. Haynes, and R. G. Webster. 1995. DNA vaccines: a new approach to immunizations, p. 69-75. In F. Brown, R. M. Channock, H. S. Ginsberg, and E. Norrby (ed.), Vaccines 95: molecular approaches to the control of infectious diseases. Cold Spring Harbor Laboratory Press, Cold Spring Harbor. N.Y.
22. Robinson, H. L., L. A. Hunt, and R. G. Webster. 1993. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 11:957.
23. Schlesinger, R. W., G. L. Bradshaw, F. Barbone, M. Reinacher, R. Roll, and P. Husak. 1989. Role of hemagglutinin cleavage and expression of M1 protein in replication of A/WS/33, A/PR/8/34, and WSN influenza viruses in mouse brain. J. Virol. 63:1695-1703.
24. Scholtissek, C., A. Vallbracht, B. Flehmig, and R. Rott. 1979. Correlation of pathogenicity and gene constellation of influenza A viruses. II. Highly neurovirulent recombinants derived from non-neurovirulent or weakly neurovirulent parent virus strains. Virology 95:492-500.
25. Sedegah, M., R. Hedstrom, P. Hobart, and S. L. Hoffman. 1994. Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc. Natl. Acad. Sci. USA 91:9866-9870.
26. Subbarao, K., A. Klimov, J. Katz, H. Regnery, W. Lim, H. Hall, M. Perdue, D. Swayne, C. Bender, J. Huang, M. Hemphill, T. Rowe, M. Shaw, X. Xu, K. Fukuda, and N. J. Cox. 1998. Characterization of an avian influenza A(H5N1) virus isolated from a child with a fatal respiratory illness. Science 279:393-396.
27. Ulmer, J. B., J. J. Donnelly, S. E. Parker, G. H. Rhodes, P. L. Felgner, V. J. Dwarki, S. H. Gromkowski, R. R. Deck, C. M. DeWitt, A. Friedman, L. A. Hawe, K. R. Leander, D. Martinez, H. C. Perry, J. W. Shiver, D. L. Montgomery, and M. A. Liu. 1993. Heterologous protection against influenza by injection of DNA encoding a viral protein Science 259:1745-1749.
28. Ward, A. C. 1995. Specific changes in the M1 protein during adaptation of influenza virus to mouse. Arch. Virol. 140:383-389.
29. Webster, R. G. 1997. Predictions for future human influenza pandemics. J. Infect. Dis. 176:S14-S19.
30. Webster, R. G., E. F. Fynan, J. C. Santro, and H. L. Robinson. 1994. Protection of ferrets against influenza challenge with a DNA vaccine to haemagglutinin. Vaccine 12:1495-1498.
31. WHO Collaborating Center for Reference and Research on Influenza. 1982. Concepts and procedures for laboratory based influenza surveillance, B-19. Centers for Disease Control, Atlanta, Ga.
32. Wood, J. M., Y. Kawaoka, L. A. Newberry, E. Bordwell, and R. G. Webster. 1985. Standardization of inactivated H5N2 influenza vaccine and efficacy against lethal A/Chicken/Pennsylvania/1370/83 infection. Avian Dis. 29:867-872.