A DNA prime, orally delivered protein boost vaccination strategy against viral encephalitis

Journal of NeuroVirology

Volumn 13, Issue 3, 2007, Pages 284-289

  Zanin, Mark P ^a   Webster, Diane E ^a,b   Wesselingh, Steven L ^a,c  

^a MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH   (Australia)

^b Department of Immunology   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Arbovirus; DNA; Encephalitis; Mucosal; Oral; Prime boost; Sindbis virus; Vaccination

Indexed keywords

DNA VACCINE; GLYCOPROTEIN E2 MALTOSE BINDING FUSION PROTEIN; HYBRID PROTEIN; SAPONIN DERIVATIVE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG SCREENING; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SINDBIS VIRUS; VACCINATION; VIRUS ENCEPHALITIS;

ADMINISTRATION, ORAL; ALPHAVIRUS INFECTIONS; ANIMALS; DISEASE MODELS, ANIMAL; DNA, VIRAL; ENCEPHALITIS, VIRAL; FEMALE; IMMUNIZATION, SECONDARY; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED BALB C; SINDBIS VIRUS; VACCINES;

ARBOVIRUS; FLAVIVIRIDAE; MURINAE; SINDBIS VIRUS; TOGAVIRIDAE;

EID: 34447321575     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280701329646     Document Type: Article

References (24)

1. Berg, S. W., Mitchell, B. S., Hanson, R. K., Olafson, R. P., Williams, R. P., Tueller, J. E., Burton, R. J., Novak, D. M., Tsai, T. F. and Wignall, F. S. (1997) Systemic reactions in U.S. Marine Corps personnel who received Japanese encephalitis vaccine. Clin Infect Dis, 24, pp. 265-266.
2. Binder, G. K. and Griffin, D. E. (2001) Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons. Science, 293, pp. 303-306.
3. Chen, H. W., Pan, C. H., Liau, M. Y., Jou, R., Tsai, C. J., Wu, H. J., Lin, Y. L. and Tao, M. H. (1999) Screening of protective antigens of Japanese encephalitis virus by DNA immunization: A comparative study with conventional viral vaccines. J Virol, 73, pp. 10137-10145.
4. Deliyannis, G., Boyle, J. S., Brady, J. L., Brown, L. E. and Lew, A. M. (2000) A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge. Proc Natl Acad Sci USA, 97, pp. 6676-6680.
5. Dropulic, L. K., Hardwick, J. M. and Griffin, D. E. (1997) A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication. J Virol, 71, pp. 6100-6105.
6. Griffin, D. E. (1981) Immunoglobulins in the cerebrospinal fluid: changes during acute viral encephalitis in mice. J Immunol, 126, pp. 27-31.
7. Griffin, D. E. and Johnson, R. T. (1977) Role of the immune response in recovery from Sindbis virus encephalitis in mice. J Immunol, 118, pp. 1070-1075.
8. Hanna, J. N., Ritchie, S. A., Phillips, D. A., Lee, J. M., Hills, S. L., Hurk, A F van den, Pyke, A. T., Johansen, C. A. and Mackenzie, J. S. (1999) Japanese encephalitis in north Queensland, Australia, 1998. Med J Aust, 170, pp. 533-536.
9. Hanna, J. N., Ritchie, S. A., Phillips, D. A., Shield, J., Bailey, M. C., Mackenzie, J. S., Poidinger, M., McCall, B. J. and Mills, P. J. (1996) An outbreak of Japanese encephalitis in the Torres Strait, Australia, 1995. Med J Aust, 165, pp. 256-260.
10. Igarashi, A., Tanaka, M., Morita, K., Takasu, T., Ahmed, A., Akram, D. S. and Waqar, M. A. (1994) Detection of west Nile and Japanese encephalitis viral genome sequences in cerebrospinal fluid from acute encephalitis cases in Karachi, Pakistan. Microbiol Immunol, 38, pp. 827-830.
11. Jan, J. T. and Griffin, D. E. (1999) Induction of apoptosis by Sindbis virus occurs at cell entry and does not require virus replication. J Virol, 73, pp. 10296-10302.
12. Labrada, L., Liang, X. H., Zheng, W., Johnston, C. and Levine, B. (2002) Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12. J Virol, 76, pp. 11688-11703.
13. Levine, B., Hardwick, J. M., Trapp, B. D., Crawford, T. O., Bollinger, R. C. and Griffin, D. E. (1991) Antibody-mediated clearance of alphavirus infection from neurons. Science, 254, pp. 856-860.
14. Maharaj, I., Froh, K. J. and Campbell, J. B. (1986) Immune responses of mice to inactivated rabies vaccine administered orally: Potentiation by Quillajasaponin. Can J Microbiol, 32, pp. 414-420.
15. Nargi-Aizenman, J. L. and Griffin, D. E. (2001) Sindbis virus-induced neuronal death is both necrotic and apoptotic and is ameliorated by N-methyl-d-aspartate receptor antagonists. J Virol, 75, pp. 7114-7121.
16. Perkins, S. D., O'Brien, L. M. and Phillpotts, R. J. (2006) Boosting with an adenovirus-based vaccine improves protective efficacy against Venezuelan equine encephalitis virus following DNA vaccination. Vaccine, 24, pp. 3440-3445.
17. Pickering, R. J., Smith, S. D., Strugnell, R. A., Wesselingh, S. L. and Webster, D. E. (2006) Crude saponins improve the immune response to an oral plant-made measles vaccine. Vaccine, 24, pp. 144-150.
18. Ramakrishna, C., Desai, A., Shankar, S. K., Chandramuki, A. and Ravi, V. (1999) Oral immunisation of mice with live Japanese encephalitis virus induces a protective immune response. Vaccine, 17, pp. 3102-3108.
19. Rowell, J. F. and Griffin, D. E. (2002) Contribution of T cells to mortality in neurovirulent Sindbis virus encephalomyelitis. J Neuroimmunol, 127, pp. 106-114.
20. Schoepp, R. J. and Johnston, R. E. (1993) Directed mutagenesis of a Sindbis virus pathogenesis site. Virology, 193, pp. 149-159.
21. Tsai, T. F., Chang, G. J. and Yu, Y. X. (1999) Japanese Encephalitis Vaccines. Vaccines, pp. 672-710. WB Saunders, Philadelphia
22. Ubol, S., Levine, B., Lee, S. H., Greenspan, N. S. and Griffin, D. E. (1995) Roles of immunoglobulin valency and the heavy-chain constant domain in antibody-mediated downregulation of Sindbis virus replication in persistently infected neurons. J Virol, 69, pp. 1990-1993.
23. WHO (2006) Japanese encephalitis vaccines. Wkly Epidemiol Rec, 81, pp. 331-340.
24. Zheng, B. J., Ng, M. H., Chan, K. W., Tam, S., Woo, P. C., Ng, S. P. and Yuen, K. Y. (2002) A single dose of oral DNA immunization delivered by attenuated Salmonella typhimuriumdown-regulates transgene expression in HBsAg transgenic mice. Eur J Immunol, 32, pp. 3294-3304.