Reversed-phase ion-pair liquid chromatography analysis and purification of small interfering RNA

Analytical Biochemistry

Volumn 390, Issue 2, 2009, Pages 181-188

  McCarthy, Sean M ^a   Gilar, Martin ^a   Gebler, John ^a  

^a WATERS CORPORATION   (United States)

Author keywords

DNA; Double stranded; Duplex; HPLC; Mass spectrometry; Oligonucleotide; RNA; Ultra performance liquid chromatography (UPLC)

Indexed keywords

DNA; DRUG PRODUCTS; LIQUIDS; MASS SPECTROMETRY; OLIGONUCLEOTIDES; PURIFICATION; RNA;

DOUBLE-STRANDED; DUPLEX; HPLC; ION PAIR LIQUID CHROMATOGRAPHY; SMALL INTERFERING RNA; SMALL INTERFERING RNA (SIRNA); THERAPEUTIC APPLICATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

COMPLEMENTARY RNA; DOUBLE STRANDED RNA; SINGLE STRANDED RNA; SMALL INTERFERING RNA;

ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; GENETIC STABILITY; ION PAIR CHROMATOGRAPHY; PRIORITY JOURNAL; REACTION TIME; REVERSED PHASE LIQUID CHROMATOGRAPHY; RNA ANALYSIS; RNA PURIFICATION; SEPARATION TECHNIQUE;

EID: 65849216592     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.03.042     Document Type: Article

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