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Volumn 5, Issue 1, 2010, Pages 53-69

Antisense oligonucleotides as an innovative therapeutic strategy in the treatment of high-grade gliomas

Author keywords

Angiogenesis; Antisense oligonucleotides; Extracellular matrix proteins; High grade gliomas; Nanoparticles

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CARBON NANOTUBE; CGP 69846A; FIBRONECTIN; HYALURONIC ACID; INTEGRIN; LAMININ; MATRIX METALLOPROTEINASE; NANOPARTICLE; NANOSHELL; PRODRUG; QUANTUM DOT; TENASCIN; VITRONECTIN; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; SCLEROPROTEIN;

EID: 77449153837     PISSN: 15748898     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488910789753503     Document Type: Review
Times cited : (28)

References (152)
  • 2
    • 0034987702 scopus 로고    scopus 로고
    • Malignant glioma: Genetics and biology of a grave matter
    • Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: Genetics and biology of a grave matter. Genes Dev 2001; 15(11): 1311-1333.
    • (2001) Genes Dev , vol.15 , Issue.11 , pp. 1311-1333
    • Maher, E.A.1    Furnari, F.B.2    Bachoo, R.M.3
  • 3
    • 0020657742 scopus 로고
    • Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme
    • Burger PC, Dubois PJ, Schold SC, et al. Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme. J Neurosurg 1983; 58(2): 159-169.
    • (1983) J Neurosurg , vol.58 , Issue.2 , pp. 159-169
    • Burger, P.C.1    Dubois, P.J.2    Schold, S.C.3
  • 4
    • 0026455838 scopus 로고
    • Supratentorial malignant glioma: Patterns of recurrence and implications for external beam local treatment
    • Gaspar LE, Fisher BJ, MacDonald DR, et al. Supratentorial malignant glioma: Patterns of recurrence and implications for external beam local treatment. Int J Radiat Oncol Biol Phys 1992; 24(1): 55-57.
    • (1992) Int J Radiat Oncol Biol Phys , vol.24 , Issue.1 , pp. 55-57
    • Gaspar, L.E.1    Fisher, B.J.2    MacDonald, D.R.3
  • 5
    • 0033941733 scopus 로고    scopus 로고
    • Temozolomide and treatment of malignant glioma
    • Friedman HS, Kerby T, Calvert H. Temozolomide and treatment of malignant glioma. Clin Cancer Res 2000; 6(7): 2585-2597.
    • (2000) Clin Cancer Res , vol.6 , Issue.7 , pp. 2585-2597
    • Friedman, H.S.1    Kerby, T.2    Calvert, H.3
  • 6
    • 33644675410 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft
    • Cheng CL, Johnson SP, Keir ST, et al. Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft. Mol Cancer Ther 2005; 4(9): 1364-1368.
    • (2005) Mol Cancer Ther , vol.4 , Issue.9 , pp. 1364-1368
    • Cheng, C.L.1    Johnson, S.P.2    Keir, S.T.3
  • 7
    • 27744439793 scopus 로고    scopus 로고
    • Glioblastoma multiforme and the epidermal growth factor receptor
    • Friedman HS, Bigner DD. Glioblastoma multiforme and the epidermal growth factor receptor. N Engl J Med 2005; 353(19): 1997-1999.
    • (2005) N Engl J Med , vol.353 , Issue.19 , pp. 1997-1999
    • Friedman, H.S.1    Bigner, D.D.2
  • 8
    • 23944449547 scopus 로고    scopus 로고
    • Successful combination of local CpG-ODN and radiotherapy in malignant glioma
    • Meng Y, Carpentier AF, Chen L, et al. Successful combination of local CpG-ODN and radiotherapy in malignant glioma. Int J Cancer 2005; 116(6): 992-997.
    • (2005) Int J Cancer , vol.116 , Issue.6 , pp. 992-997
    • Meng, Y.1    Carpentier, A.F.2    Chen, L.3
  • 9
    • 32944469010 scopus 로고    scopus 로고
    • Changing paradigms: An update on the multidisciplinary management of malignant glioma
    • Stupp R, Hegi ME, van den Bent MJ, et al. Changing paradigms: An update on the multidisciplinary management of malignant glioma. Oncologist 2006; 11(2): 165-180.
    • (2006) Oncologist , vol.11 , Issue.2 , pp. 165-180
    • Stupp, R.1    Hegi, M.E.2    Van Den Bent, M.J.3
  • 10
    • 33748376520 scopus 로고    scopus 로고
    • Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08
    • Wen PY, Yung WK, Lamborn KR, et al. Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08. Clin Cancer Res 2006; 12(16): 4899-4907.
    • (2006) Clin Cancer Res , vol.12 , Issue.16 , pp. 4899-4907
    • Wen, P.Y.1    Yung, W.K.2    Lamborn, K.R.3
  • 11
    • 33644787355 scopus 로고    scopus 로고
    • Gliadel((R)) wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial
    • Westphal M, Ram Z, Riddle V, Hilt D, Bortey E. Gliadel((R)) wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial. Acta Neurochir 2006; 148(3): 269-275.
    • (2006) Acta Neurochir , vol.148 , Issue.3 , pp. 269-275
    • Westphal, M.1    Ram, Z.2    Riddle, V.3    Hilt, D.4    Bortey, E.5
  • 12
    • 2942567848 scopus 로고    scopus 로고
    • Immunotherapeutic strategies for malignant glioma
    • Fenstermaker RA, Ciesielski MJ. Immunotherapeutic strategies for malignant glioma. Cancer Control 2004; 11(3): 181-191.
    • (2004) Cancer Control , vol.11 , Issue.3 , pp. 181-191
    • Fenstermaker, R.A.1    Ciesielski, M.J.2
  • 13
    • 24944552128 scopus 로고    scopus 로고
    • Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines
    • Kjaergaard J, Wang LX, Kuriyama H, Shu S, Plautz GE. Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines. J Neurosurg 2005; 103(1): 156-164.
    • (2005) J Neurosurg , vol.103 , Issue.1 , pp. 156-164
    • Kjaergaard, J.1    Wang, L.X.2    Kuriyama, H.3    Shu, S.4    Plautz, G.E.5
  • 14
    • 27944478578 scopus 로고    scopus 로고
    • Treatment of astrocytomas
    • Gonzalez J, Gilbert MR. Treatment of astrocytomas. Curr Opin Neurol 2005; 18(6): 632-638.
    • (2005) Curr Opin Neurol , vol.18 , Issue.6 , pp. 632-638
    • Gonzalez, J.1    Gilbert, M.R.2
  • 15
    • 25144436834 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma: Current clinical status
    • Pulkkanen KJ, Yla-Herttuala S. Gene therapy for malignant glioma: Current clinical status. Mol Ther 2005; 12(4): 585-598.
    • (2005) Mol Ther , vol.12 , Issue.4 , pp. 585-598
    • Pulkkanen, K.J.1    Yla-Herttuala, S.2
  • 16
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352(10): 987-996.
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 17
    • 33748916963 scopus 로고    scopus 로고
    • Molecular changes in brain tumors: Prognostic and therapeutic impact
    • Sanson M, Laigle-Donadey F, Benouaich-Amiel A. Molecular changes in brain tumors: Prognostic and therapeutic impact. Curr Opin Oncol 2006; 18(6): 623-630.
    • (2006) Curr Opin Oncol , vol.18 , Issue.6 , pp. 623-630
    • Sanson, M.1    Laigle-Donadey, F.2    Benouaich-Amiel, A.3
  • 18
    • 33646234949 scopus 로고    scopus 로고
    • Cerebral radiation necrosis: Incidence, outcomes, and risk factors with emphasis on radiation parameters and chemotherapy
    • Ruben JD, Dally M, Bailey M, et al. Cerebral radiation necrosis: Incidence, outcomes, and risk factors with emphasis on radiation parameters and chemotherapy. Int J Radiat Oncol Biol Phys 2006; 65(2): 499-508.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , Issue.2 , pp. 499-508
    • Ruben, J.D.1    Dally, M.2    Bailey, M.3
  • 19
    • 0029952813 scopus 로고    scopus 로고
    • Role of extracellular matrix proteins in regulation of human glioma cell invasion in vitro
    • Chintala SK, Gokaslan ZL, Go Y, Sawaya R, Nicolson GL, Rao JS. Role of extracellular matrix proteins in regulation of human glioma cell invasion in vitro. Clin Exp Metastasis 1996; 14(4): 358-366.
    • (1996) Clin Exp Metastasis , vol.14 , Issue.4 , pp. 358-366
    • Chintala, S.K.1    Gokaslan, Z.L.2    Go, Y.3    Sawaya, R.4    Nicolson, G.L.5    Rao, J.S.6
  • 20
    • 0029995767 scopus 로고    scopus 로고
    • Glioma invasion in the central nervous system
    • Giese A, Westphal M. Glioma invasion in the central nervous system. Neurosurgery 1996; 39(2): 235-252.
    • (1996) Neurosurgery , vol.39 , Issue.2 , pp. 235-252
    • Giese, A.1    Westphal, M.2
  • 21
    • 0029981104 scopus 로고    scopus 로고
    • Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies
    • Tysnes BB, Larsen LF, Ness GO, et al. Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies. Int J Cancer 1996; 67(6): 777-784.
    • (1996) Int J Cancer , vol.67 , Issue.6 , pp. 777-784
    • Tysnes, B.B.1    Larsen, L.F.2    Ness, G.O.3
  • 22
    • 0032958428 scopus 로고    scopus 로고
    • Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro
    • Tonn JC, Kerkau S, Hanke A, et al. Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro. Int J Cancer 1999; 80(5): 764-772.
    • (1999) Int J Cancer , vol.80 , Issue.5 , pp. 764-772
    • Tonn, J.C.1    Kerkau, S.2    Hanke, A.3
  • 23
    • 0036499078 scopus 로고    scopus 로고
    • Phase II trial of temozolamide plus the matrx metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme
    • Groves MD, Puduvalli VK, Hess KR, et al. Phase II trial of temozolamide plus the matrx metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme. J Clin Oncol 2002; 20(5): 1383-1388.
    • (2002) J Clin Oncol , vol.20 , Issue.5 , pp. 1383-1388
    • Groves, M.D.1    Puduvalli, V.K.2    Hess, K.R.3
  • 24
    • 0036498790 scopus 로고    scopus 로고
    • Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
    • Reardon DA, Akabani G, Coleman RE, et al. Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol 2002; 20(14): 1389-1397.
    • (2002) J Clin Oncol , vol.20 , Issue.14 , pp. 1389-1397
    • Reardon, D.A.1    Akabani, G.2    Coleman, R.E.3
  • 25
    • 0037279647 scopus 로고    scopus 로고
    • Replicative retroviral vectors for cancer gene therapy
    • Solly SK, Trajcevski S, Frisen C, et al. Replicative retroviral vectors for cancer gene therapy. Cancer Gene Ther 2003; 10: 30-39.
    • (2003) Cancer Gene Ther , vol.10 , pp. 30-39
    • Solly, S.K.1    Trajcevski, S.2    Frisen, C.3
  • 26
    • 13644257013 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein
    • Zhang J, Frolov I, Russell SJ. Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein. J Gene Med 2004; 6(10): 1082-1091.
    • (2004) J Gene Med , vol.6 , Issue.10 , pp. 1082-1091
    • Zhang, J.1    Frolov, I.2    Russell, S.J.3
  • 27
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100(1): 57-70.
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 28
    • 0035256772 scopus 로고    scopus 로고
    • Gliomagenesis: Genetic alterations and mouse models
    • Holland EC. Gliomagenesis: Genetic alterations and mouse models. Nat Rev Genet 2001; 2(2): 120-129.
    • (2001) Nat Rev Genet , vol.2 , Issue.2 , pp. 120-129
    • Holland, E.C.1
  • 29
    • 33846120996 scopus 로고    scopus 로고
    • BcI2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma
    • Stegh AH, Kim H, Bachoo RM, et al. BcI2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes Dev 2007; 21: 98-111.
    • (2007) Genes Dev , vol.21 , pp. 98-111
    • Stegh, A.H.1    Kim, H.2    Bachoo, R.M.3
  • 30
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • Ohgaki K, Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol 2007; 170(5): 1445-1453.
    • (2007) Am J Pathol , vol.170 , Issue.5 , pp. 1445-1453
    • Ohgaki, K.1    Kleihues, P.2
  • 31
    • 0021080454 scopus 로고
    • Pathologic anatomy and CT correlations in the glioblastoma multiforme
    • Burger PC. Pathologic anatomy and CT correlations in the glioblastoma multiforme. Appl Neurophysiol 1983; 46(1-4): 180-187.
    • (1983) Appl Neurophysiol , vol.46 , Issue.1-4 , pp. 180-187
    • Burger, P.C.1
  • 32
    • 0028944106 scopus 로고
    • Molecular insights into cancer invasion: Strategies for prevention and intervention
    • Kohn EC, Liotta LA. Molecular insights into cancer invasion: Strategies for prevention and intervention. Cancer Res 1995; 55(9): 1856-1862.
    • (1995) Cancer Res , vol.55 , Issue.9 , pp. 1856-1862
    • Kohn, E.C.1    Liotta, L.A.2
  • 33
    • 0030046268 scopus 로고    scopus 로고
    • Immunohistochemical localization of extracellular matrix proteins in human glioma, both in vivo and in vitro
    • Chintala SK, Sawaya R, Gokaslan ZL, Fuller G, Rao JS. Immunohistochemical localization of extracellular matrix proteins in human glioma, both in vivo and in vitro. Cancer Lett 1996; 101(1): 107-114.
    • (1996) Cancer Lett , vol.101 , Issue.1 , pp. 107-114
    • Chintala, S.K.1    Sawaya, R.2    Gokaslan, Z.L.3    Fuller, G.4    Rao, J.S.5
  • 34
    • 0031059914 scopus 로고    scopus 로고
    • The extracellular matrix in neural crest-cell migration
    • Perris R. The extracellular matrix in neural crest-cell migration. Trends Neurosci 1997; 20(1): 23-30.
    • (1997) Trends Neurosci , vol.20 , Issue.1 , pp. 23-30
    • Perris, R.1
  • 35
    • 0001744359 scopus 로고    scopus 로고
    • Brain extracellular matrix, adhesion molecules, and glioma invasion
    • Mikkelsen T, Bjerkvig R, Laerum OD, Rosenblum ML, Ed. New York: Wiley-Liss
    • Paulus W. Brain extracellular matrix, adhesion molecules, and glioma invasion. In: Mikkelsen T, Bjerkvig R, Laerum OD, Rosenblum ML, Ed. Brain Tumor Invasion: Biological, Clinical and Therapeutic Considerations. New York: Wiley-Liss 1998.
    • (1998) Brain Tumor Invasion: Biological, Clinical and Therapeutic Considerations
    • Paulus, W.1
  • 36
    • 0033103707 scopus 로고    scopus 로고
    • Integrin subunit gene expression is regionally differentiated in adult brain
    • Pinkstaff K, Detterich J, Lynch G, Gall C. Integrin subunit gene expression is regionally differentiated in adult brain. J Neurosci 1999; 19(5): 1541-1556.
    • (1999) J Neurosci , vol.19 , Issue.5 , pp. 1541-1556
    • Pinkstaff, K.1    Detterich, J.2    Lynch, G.3    Gall, C.4
  • 37
    • 0030047323 scopus 로고    scopus 로고
    • Integrins: Possible functions in the adult CNS
    • Jones LS. Integrins: Possible functions in the adult CNS. Trends Neurosci 1996; 19(2): 68-72.
    • (1996) Trends Neurosci , vol.19 , Issue.2 , pp. 68-72
    • Jones, L.S.1
  • 38
    • 0032876723 scopus 로고    scopus 로고
    • The role of integrin receptors in aspects of glioma invasion in vitro
    • Rooprai HK, Vanmeter T, Panou C, et al. The role of integrin receptors in aspects of glioma invasion in vitro. Int J Dev Neurosci 1999; 17(5-6): 613-623.
    • (1999) Int J Dev Neurosci , vol.17 , Issue.5-6 , pp. 613-623
    • Rooprai, H.K.1    Vanmeter, T.2    Panou, C.3
  • 39
    • 0028940958 scopus 로고
    • Cerebral microenviroment influences expression of the vitronectin gene in astrocytic tumors
    • Gladson CL, Wilcox JN, Sanders L, Gillespie GY, Cheresh DH. Cerebral microenviroment influences expression of the vitronectin gene in astrocytic tumors. J Cell Sci 1995; 108(Pt 3): 947-956.
    • (1995) J Cell Sci , vol.108 , Issue.PART 3 , pp. 947-956
    • Gladson, C.L.1    Wilcox, J.N.2    Sanders, L.3    Gillespie, G.Y.4    Cheresh, D.H.5
  • 40
    • 17844367105 scopus 로고    scopus 로고
    • Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery
    • Bello L, Francolini M, Marthyn P, et al. Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. Neurosurgery 2001; 49(2): 380-389.
    • (2001) Neurosurgery , vol.49 , Issue.2 , pp. 380-389
    • Bello, L.1    Francolini, M.2    Marthyn, P.3
  • 41
    • 0029846478 scopus 로고    scopus 로고
    • Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors
    • Gladson CL. Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors. J Neuropathol Exp Neurol 1996; 55(11): 1143-1149.
    • (1996) J Neuropathol Exp Neurol , vol.55 , Issue.11 , pp. 1143-1149
    • Gladson, C.L.1
  • 42
    • 0028625739 scopus 로고
    • The family of matrix metalloproteinases
    • Woessner JF. The family of matrix metalloproteinases. Ann NY Acad Sci 1994; 732: 11-21.
    • (1994) Ann NY Acad Sci , vol.732 , pp. 11-21
    • Woessner, J.F.1
  • 43
    • 0031049327 scopus 로고    scopus 로고
    • Mechanisms of glioma invasion: Role of matrix metalloproteinases
    • Uhm JH, Dooley NP, Villemure J-G, Yong VW. Mechanisms of glioma invasion: Role of matrix metalloproteinases. Can J Neurol Sci 1997; 24(1): 3-15.
    • (1997) Can J Neurol Sci , vol.24 , Issue.1 , pp. 3-15
    • Uhm, J.H.1    Dooley, N.P.2    Villemure, J.-G.3    Yong, V.W.4
  • 44
    • 2342431428 scopus 로고    scopus 로고
    • Angiogenesis and invasion in gliomas
    • Bello L, Giussani C, Costa F, et al. Angiogenesis and invasion in gliomas. Cancer Treat Res 2004; 117: 263-284.
    • (2004) Cancer Treat Res , vol.117 , pp. 263-284
    • Bello, L.1    Giussani, C.2    Costa, F.3
  • 45
    • 6344276541 scopus 로고    scopus 로고
    • An immunohistochemical study of extracellular matrix proteins laminin, fibronectin and type IV collagen in paediatric glioblastoma multiforme
    • Wien
    • Caffo M, Germanò A, Caruso G, et al. An immunohistochemical study of extracellular matrix proteins laminin, fibronectin and type IV collagen in paediatric glioblastoma multiforme. Acta Neurochir (Wien) 2004; 146(10): 1113-1118.
    • (2004) Acta Neurochir , vol.146 , Issue.10 , pp. 1113-1118
    • Caffo, M.1    Germanò, A.2    Caruso, G.3
  • 46
    • 0035254648 scopus 로고    scopus 로고
    • Angiogenesis: Regulators and clinical application
    • Liekens S, De Clercq E, Neyts J. Angiogenesis: Regulators and clinical application. Biochem Pharmacol 2001; 61(3): 253-270.
    • (2001) Biochem Pharmacol , vol.61 , Issue.3 , pp. 253-270
    • Liekens, S.1    De Clercq, E.2    Neyts, J.3
  • 47
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86(3): 353-364.
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 48
    • 33947201169 scopus 로고    scopus 로고
    • Expression of VEGFR3 in glioma endothelium correlates with tumor grade
    • Grau SJ, Trillsch F, Herms J, et al. Expression of VEGFR3 in glioma endothelium correlates with tumor grade. J Neurooncol 2007; 82(2): 141-150.
    • (2007) J Neurooncol , vol.82 , Issue.2 , pp. 141-150
    • Grau, S.J.1    Trillsch, F.2    Herms, J.3
  • 49
    • 0035173182 scopus 로고    scopus 로고
    • VEGFR-3 in adult angiogenesis
    • Witmer AN, van Blijswijk BC, Dai J, et al. VEGFR-3 in adult angiogenesis. J Pathol 2001; 195(4): 490-497.
    • (2001) J Pathol , vol.195 , Issue.4 , pp. 490-497
    • Witmer, A.N.1    Van Blijswijk, B.C.2    Dai, J.3
  • 51
    • 33645694302 scopus 로고    scopus 로고
    • Different angiogenic phenotypes in primary and secondary glioblastomas
    • Karcher S, Steiner HH, Ahmadi R, et al. Different angiogenic phenotypes in primary and secondary glioblastomas. Int J cancer 2006; 118(9): 2182-2189.
    • (2006) Int J Cancer , vol.118 , Issue.9 , pp. 2182-2189
    • Karcher, S.1    Steiner, H.H.2    Ahmadi, R.3
  • 52
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. Microglia: A sensor for pathological events in the CNS. Trends Neurosci 1996; 19(8): 312-318.
    • (1996) Trends Neurosci , vol.19 , Issue.8 , pp. 312-318
    • Kreutzberg, G.W.1
  • 53
    • 0025911287 scopus 로고
    • Microglia in human disease, with an emphasis on acquired immune deficiency syndrome
    • Dickson DW, Mattiace LA, Kure K, Hutchins K. Microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab Invest 1991; 64(2): 134-156.
    • (1991) Lab Invest , vol.64 , Issue.2 , pp. 134-156
    • Dickson, D.W.1    Mattiace, L.A.2    Kure, K.3    Hutchins, K.4
  • 54
    • 0035338196 scopus 로고    scopus 로고
    • Activation of human macrophages by amyloid-beta is attenuated by astrocytes
    • Smits HA, van Beelen AJ, de Vos NM, et al. Activation of human macrophages by amyloid-beta is attenuated by astrocytes. J Immunol 2001; 166(11): 6869-6876.
    • (2001) J Immunol , vol.166 , Issue.11 , pp. 6869-6876
    • Smits, H.A.1    Van Beelen, A.J.2    De Vos, N.M.3
  • 55
    • 0036839143 scopus 로고    scopus 로고
    • Macrophages polarization: Tumor associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophages polarization: Tumor associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23(11): 549-555.
    • (2002) Trends Immunol , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 56
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nature Rev Cancer 2004; 4: 71-78.
    • (2004) Nature Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 57
    • 0031866813 scopus 로고    scopus 로고
    • Differential expression of MHC class II molecules by microglia and neoplastic astroglia: Relevance for the escape of astrocytoma cells from immune surveillance
    • Tran CT, Wolz P, Egensperger R, et al. Differential expression of MHC class II molecules by microglia and neoplastic astroglia: Relevance for the escape of astrocytoma cells from immune surveillance. Neuropathol Appl Neurobiol 1998; 24(2): 293-301.
    • (1998) Neuropathol Appl Neurobiol , vol.24 , Issue.2 , pp. 293-301
    • Tran, C.T.1    Wolz, P.2    Egensperger, R.3
  • 58
    • 0032926784 scopus 로고    scopus 로고
    • Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas
    • Nishie A, Ono M, Shono T, et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin Cancer Res 1999; 5(5): 1107-1113.
    • (1999) Clin Cancer Res , vol.5 , Issue.5 , pp. 1107-1113
    • Nishie, A.1    Ono, M.2    Shono, T.3
  • 59
    • 0033526179 scopus 로고    scopus 로고
    • Carrier-mediated or specialized transport of drugs across the blood-brain barrier
    • DOI 10.1016/S0169-409X(98)00084-2, PII S0169409X98000842
    • Tsuij A, Tamai I. Carrier-mediated or specialized transport of drugs across the blood-brain barrier. Adv Drug Deliv Rev 1999; 36(2-3): 277-290. (Pubitemid 29121976)
    • (1999) Advanced Drug Delivery Reviews , vol.36 , Issue.2-3 , pp. 277-290
    • Tsuji, A.1    Tamai, I.2
  • 60
    • 0036007257 scopus 로고    scopus 로고
    • Why is the global CNS pharmaceutical market so underpenetrated?
    • Pardridge WM. Why is the global CNS pharmaceutical market so underpenetrated? Drug Discov Today 2002; 7(1): 5-7.
    • (2002) Drug Discov Today , vol.7 , Issue.1 , pp. 5-7
    • Pardridge, W.M.1
  • 61
    • 0041837255 scopus 로고    scopus 로고
    • Blood brain barrier efflux transport
    • Golden PL, Pollack GM. Blood brain barrier efflux transport. J Pharm Sci 2003; 92(9): 1739-1753.
    • (2003) J Pharm Sci , vol.92 , Issue.9 , pp. 1739-1753
    • Golden, P.L.1    Pollack, G.M.2
  • 62
    • 0141764816 scopus 로고    scopus 로고
    • Drug delivery to the central nervous system: A review
    • Misra A, Ganesh S, Shahiwala A, Shah SP. Drug delivery to the central nervous system: A review. J Pharm Pharm Sci 2003; 6(2): 252-273.
    • (2003) J Pharm Pharm Sci , vol.6 , Issue.2 , pp. 252-273
    • Misra, A.1    Ganesh, S.2    Shahiwala, A.3    Shah, S.P.4
  • 63
    • 33748344520 scopus 로고    scopus 로고
    • Nanotechnology in cancer therapeutics: Bioconjugated nanoparticles for drug delivery
    • Sinha R, Kim GJ, Nie S, Shin DM. Nanotechnology in cancer therapeutics: Bioconjugated nanoparticles for drug delivery. Mol Canc Ther 2006; 5(8): 1909-1917.
    • (2006) Mol Canc Ther , vol.5 , Issue.8 , pp. 1909-1917
    • Sinha, R.1    Kim, G.J.2    Nie, S.3    Shin, D.M.4
  • 65
    • 61349139614 scopus 로고    scopus 로고
    • Drug delivery and nanoparticles: Applications and hazards
    • De Jong WH, Borm PJA. Drug delivery and nanoparticles: Applications and hazards. Int J Nanomed 2008; 3(2): 133-149.
    • (2008) Int J Nanomed , vol.3 , Issue.2 , pp. 133-149
    • De Jong, W.H.1    Borm, P.J.A.2
  • 66
    • 33947278926 scopus 로고    scopus 로고
    • Antimicrobial effects of silver nanoparticles
    • Kim JS, Kuk E, Yu KN, et al. Antimicrobial effects of silver nanoparticles. Nanomedicine 2007; 3: 95-101.
    • (2007) Nanomedicine , vol.3 , pp. 95-101
    • Kim, J.S.1    Kuk, E.2    Yu, K.N.3
  • 67
    • 37249068935 scopus 로고    scopus 로고
    • Immunoshells for targeted phototermical ablation in medulloblastoma and glioma: An in vitro evaluation using human cell lines
    • Bernardi RJ, Lowery AR, Thompson PA, Blaney SM, West JL. Immunoshells for targeted phototermical ablation in medulloblastoma and glioma: An in vitro evaluation using human cell lines. J Neurooncol 2008; 86: 165-172.
    • (2008) J Neurooncol , vol.86 , pp. 165-172
    • Bernardi, R.J.1    Lowery, A.R.2    Thompson, P.A.3    Blaney, S.M.4    West, J.L.5
  • 68
    • 23844531202 scopus 로고    scopus 로고
    • Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction
    • Kam NW, O'Connell M, Wisdom JA, Dai H. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc Natl Acad Sci USA 2005; 102: 11600-11605.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11600-11605
    • Kam, N.W.1    O'Connell, M.2    Wisdom, J.A.3    Dai, H.4
  • 69
    • 77951115804 scopus 로고    scopus 로고
    • Phototermal ablation of stem-cell like glioblastoma using carbon nanotubes functionalized with anti-CD133
    • Wang CH, Huang YJ, Peng CA. Phototermal ablation of stem-cell like glioblastoma using carbon nanotubes functionalized with anti-CD133. Proceedings 2009; 23: 888-891.
    • (2009) Proceedings , vol.23 , pp. 888-891
    • Wang, C.H.1    Huang, Y.J.2    Peng, C.A.3
  • 70
    • 0033023072 scopus 로고    scopus 로고
    • New treatment strategies for malignant gliomas
    • Avgeropoulos NG, Batchelor TT. New treatment strategies for malignant gliomas. Oncologist 1999; 4(3): 209-224.
    • (1999) Oncologist , vol.4 , Issue.3 , pp. 209-224
    • Avgeropoulos, N.G.1    Batchelor, T.T.2
  • 71
    • 0029992327 scopus 로고    scopus 로고
    • Human malignant brain tumor response to Herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy
    • Izquierdo M, Martin V, de Felipe P, et al. Human malignant brain tumor response to Herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy. Gene Ther 1996; 3(6): 491-495.
    • (1996) Gene Ther , vol.3 , Issue.6 , pp. 491-495
    • Izquierdo, M.1    Martin, V.2    De Felipe, P.3
  • 72
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector producing cells
    • Ram Z, Culver KW, Oshiro EM et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector producing cells. Nat Med 1997; 3(12): 1354-1361.
    • (1997) Nat Med , vol.3 , Issue.12 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3
  • 73
    • 33748340023 scopus 로고    scopus 로고
    • Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single walled carbon nanotubes suppresses tumor growth
    • Zhang Z, Yang S, Zhang Y, et al. Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single walled carbon nanotubes suppresses tumor growth. Clin Cancer Res 2006; 12(16): 4933-4939.
    • (2006) Clin Cancer Res , vol.12 , Issue.16 , pp. 4933-4939
    • Zhang, Z.1    Yang, S.2    Zhang, Y.3
  • 74
    • 33748428039 scopus 로고    scopus 로고
    • Crossing cellular barriers using dendrimer nanotechnologies
    • Najlah M, D'Emanuele A. Crossing cellular barriers using dendrimer nanotechnologies. Curr Opin Pharm 2006; 6: 522-527.
    • (2006) Curr Opin Pharm , vol.6 , pp. 522-527
    • Najlah, M.1    D'Emanuele, A.2
  • 75
    • 33644593095 scopus 로고    scopus 로고
    • PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, and functionality
    • Majoros IJ, Myc A, Thomas T, Mehta CB, Baker JR Jr. PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, and functionality. Biomacromolecules 2006; 7: 572-579.
    • (2006) Biomacromolecules , vol.7 , pp. 572-579
    • Majoros, I.J.1    Myc, A.2    Thomas, T.3    Mehta, C.B.4    Baker Jr., J.R.5
  • 76
    • 20444445144 scopus 로고    scopus 로고
    • Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer
    • Kukowska-Latallo JF, Candido KA, Cao Z, et al. Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res 2005; 65(12): 5317-5324.
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5317-5324
    • Kukowska-Latallo, J.F.1    Candido, K.A.2    Cao, Z.3
  • 77
    • 33845975678 scopus 로고    scopus 로고
    • Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference
    • Tan WB, Jiang S, Zhang Y. Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference. Biomaterials 2007; 28(8): 1565-1571.
    • (2007) Biomaterials , vol.28 , Issue.8 , pp. 1565-1571
    • Tan, W.B.1    Jiang, S.2    Zhang, Y.3
  • 78
    • 3142667914 scopus 로고    scopus 로고
    • The materials engineering of temperature-sensitive liposomes
    • Mills JK, Needham D. The materials engineering of temperature-sensitive liposomes. Methods Enzymol 2004; 387: 82-113.
    • (2004) Methods Enzymol , vol.387 , pp. 82-113
    • Mills, J.K.1    Needham, D.2
  • 79
    • 0034161921 scopus 로고    scopus 로고
    • A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model
    • Needham D, Anyarambhatla G, Kong G, Dewhirst MW. A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model. Cancer Res 2000; 60: 1997-11201
    • (2000) Cancer Res , vol.60 , pp. 1997-11201
    • Needham, D.1    Anyarambhatla, G.2    Kong, G.3    Dewhirst, M.W.4
  • 80
    • 0036846993 scopus 로고    scopus 로고
    • Antisense therapy for cancer - The tome of truth
    • Jansen B, Zangemeister-Wittke U. Antisense therapy for cancer - the tome of truth. Lancet Oncol 2002; 3(11): 672-683.
    • (2002) Lancet Oncol , vol.3 , Issue.11 , pp. 672-683
    • Jansen, B.1    Zangemeister-Wittke, U.2
  • 81
    • 33645563620 scopus 로고    scopus 로고
    • Antisense therapy in malignant disease: Status quo and quo vadis?
    • Tamm I. Antisense therapy in malignant disease: status quo and quo vadis? Clin Sci 2006; 110(4): 427-442.
    • (2006) Clin Sci , vol.110 , Issue.4 , pp. 427-442
    • Tamm, I.1
  • 82
    • 33745159389 scopus 로고    scopus 로고
    • Anisense molecules for targeted cancer therapy
    • Wacheck V, Zangemeister-Wittke U. Anisense molecules for targeted cancer therapy. Oncol Hematol 2006; 59(1): 65-73.
    • (2006) Oncol Hematol , vol.59 , Issue.1 , pp. 65-73
    • Wacheck, V.1    Zangemeister-Wittke, U.2
  • 83
    • 0017670013 scopus 로고
    • Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
    • Paterson BM, Roberts BE, Kuff EL. Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc Natl Acad Sci USA 1977; 74(10): 4370-4374.
    • (1977) Proc Natl Acad Sci USA , vol.74 , Issue.10 , pp. 4370-4374
    • Paterson, B.M.1    Roberts, B.E.2    Kuff, E.L.3
  • 84
    • 0005772676 scopus 로고
    • Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
    • Stephenson ML, Zamecnick PC. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci USA 1978; 75(1): 285-288.
    • (1978) Proc Natl Acad Sci USA , vol.75 , Issue.1 , pp. 285-288
    • Stephenson, M.L.1    Zamecnick, P.C.2
  • 85
    • 0026295042 scopus 로고
    • in vivo Modulation of N-myc expression by continuous perfusion with an antisense oligonucleotide
    • Whitesell L, Rosolen A, Neckers LM. in vivo Modulation of N-myc expression by continuous perfusion with an antisense oligonucleotide. Antisense Res Dev 1991; 1(4): 343-350.
    • (1991) Antisense Res Dev , vol.1 , Issue.4 , pp. 343-350
    • Whitesell, L.1    Rosolen, A.2    Neckers, L.M.3
  • 86
    • 0034853258 scopus 로고    scopus 로고
    • Discovery and analysis of antisense oligonucleotide activity in cell culture
    • Baker BF, Condon TP, Koller E, et al. Discovery and analysis of antisense oligonucleotide activity in cell culture. Methods 2001; 23(2): 191-198.
    • (2001) Methods , vol.23 , Issue.2 , pp. 191-198
    • Baker, B.F.1    Condon, T.P.2    Koller, E.3
  • 87
    • 0032724911 scopus 로고    scopus 로고
    • Novel mechanisms for antisense-mediated regulation of gene expression
    • Baker BF, Monia BP. Novel mechanisms for antisense-mediated regulation of gene expression. Biochim Biophys Acta 1999; 1489(1): 3-18.
    • (1999) Biochim Biophys Acta , vol.1489 , Issue.1 , pp. 3-18
    • Baker, B.F.1    Monia, B.P.2
  • 88
    • 0000015743 scopus 로고    scopus 로고
    • Antisense oligonucleotides: Basic concept and mechanisms
    • Dias N, Stein CA. Antisense oligonucleotides: Basic concept and mechanisms. Mol Cancer Ther 2002; 1(5): 347-355.
    • (2002) Mol Cancer Ther , vol.1 , Issue.5 , pp. 347-355
    • Dias, N.1    Stein, C.A.2
  • 89
    • 1642430704 scopus 로고    scopus 로고
    • Antisense oligonucleotide-based therapeutics for cancer
    • Dean NM, Bennett FC. Antisense oligonucleotide-based therapeutics for cancer. Oncogene 2003; 22(56): 9087-9096.
    • (2003) Oncogene , vol.22 , Issue.56 , pp. 9087-9096
    • Dean, N.M.1    Bennett, F.C.2
  • 90
    • 0034235701 scopus 로고    scopus 로고
    • Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity
    • Davila E, Celis E. Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity. J Immunol 2000; 165(1): 539-547.
    • (2000) J Immunol , vol.165 , Issue.1 , pp. 539-547
    • Davila, E.1    Celis, E.2
  • 91
    • 0034087729 scopus 로고    scopus 로고
    • Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs
    • Carpentier AF, Xie J, Mokhtari K, Delattre JY. Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs. Clin Cancer Res 2000; 6(6): 2469-2473.
    • (2000) Clin Cancer Res , vol.6 , Issue.6 , pp. 2469-2473
    • Carpentier, A.F.1    Xie, J.2    Mokhtari, K.3    Delattre, J.Y.4
  • 92
    • 0035181430 scopus 로고    scopus 로고
    • Implication of macrophages in tumor rejection induced by CpGoligodeoxynucleotides without antigen
    • Auf G, Carpentier AF, Chen L, Le Clanche C, Delattre JY. Implication of macrophages in tumor rejection induced by CpGoligodeoxynucleotides without antigen. Clin Cancer Res 2001; 7(11): 3540-3543.
    • (2001) Clin Cancer Res , vol.7 , Issue.11 , pp. 3540-3543
    • Auf, G.1    Carpentier, A.F.2    Chen, L.3    Le Clanche, C.4    Delattre, J.Y.5
  • 93
    • 0033574578 scopus 로고    scopus 로고
    • The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides
    • Ackermann EJ, Taylor JK, Narayana R, Bennett FC. The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides. J Biol Chem 1999; 274: 11245-11253.
    • (1999) J Biol Chem , vol.274 , pp. 11245-11253
    • Ackermann, E.J.1    Taylor, J.K.2    Narayana, R.3    Bennett, F.C.4
  • 94
    • 0032833451 scopus 로고    scopus 로고
    • Antisense therapy of hematologic malignancies
    • Cotter FE. Antisense therapy of hematologic malignancies. Semin Hematol 1999; 36(4 Supp 6): 9-14.
    • (1999) Semin Hematol , vol.36 , Issue.4 SUPPL. 6 , pp. 9-14
    • Cotter, F.E.1
  • 95
    • 0034015672 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-hodgkin's lymphoma
    • Waters JS, Webb A, Cunningham D, et al. Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-hodgkin's lymphoma. J Clin Oncol 1999; 18(9): 1812-1823.
    • (1999) J Clin Oncol , vol.18 , Issue.9 , pp. 1812-1823
    • Waters, J.S.1    Webb, A.2    Cunningham, D.3
  • 96
    • 0032697942 scopus 로고    scopus 로고
    • A review of issue in the pharmacokinetics and toxicology of phosphorothioate antisense olionucleotides
    • Levin AA. A review of issue in the pharmacokinetics and toxicology of phosphorothioate antisense olionucleotides. Biochim Biophys Acta 1999; 1489: 69-84.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 69-84
    • Levin, A.A.1
  • 97
    • 0030860258 scopus 로고    scopus 로고
    • Mixed backbone antisense oligonucleotides: Design, biochemical and biological properties of oligonucleotides containing 2′-5′-ribo- and 3′-5′- deoxyribonucleotide segments
    • Kandimalla ER, Manning A, Zhao Q, et al. Mixed backbone antisense oligonucleotides: Design, biochemical and biological properties of oligonucleotides containing 2′-5′-ribo- and 3′-5′- deoxyribonucleotide segments. Nucleic Acid Res 1997; 25(2): 370-378.
    • (1997) Nucleic Acid Res , vol.25 , Issue.2 , pp. 370-378
    • Kandimalla, E.R.1    Manning, A.2    Zhao, Q.3
  • 98
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: The case for an RNase H-independent structural type
    • Summerton J. Morpholino antisense oligomers: The case for an RNase H-independent structural type. Biochim Biophys Acta 1999; 1489(1): 141-158.
    • (1999) Biochim Biophys Acta , vol.1489 , Issue.1 , pp. 141-158
    • Summerton, J.1
  • 99
    • 0033633241 scopus 로고    scopus 로고
    • Antisense properties of peptide nucleic acid
    • Nielsen PE. Antisense properties of peptide nucleic acid. Methods Enzymol 2003; 313: 156-164.
    • (2003) Methods Enzymol , vol.313 , pp. 156-164
    • Nielsen, P.E.1
  • 100
    • 0034938693 scopus 로고    scopus 로고
    • Locked nucleic acids: A promising molecular family for gene-function analysis and antisense drug development
    • Orum H, Wengel J. Locked nucleic acids: A promising molecular family for gene-function analysis and antisense drug development. Curr Opin Mol Ther 2001; 3: 329-343.
    • (2001) Curr Opin Mol Ther , vol.3 , pp. 329-343
    • Orum, H.1    Wengel, J.2
  • 101
    • 0027242052 scopus 로고
    • Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy
    • Bergan L, Connell Y, Fahmy B, Neeckers L. Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy. Nucleic Acid Res 1993; 21(15): 3567-3573.
    • (1993) Nucleic Acid Res , vol.21 , Issue.15 , pp. 3567-3573
    • Bergan, L.1    Connell, Y.2    Fahmy, B.3    Neeckers, L.4
  • 102
    • 0028915281 scopus 로고
    • An assessment of the antisense properties of RNase H-component and steric-blocking oligomers
    • Bonham MA, Brown S, Boyd AL, et al. An assessment of the antisense properties of RNase H-component and steric-blocking oligomers. Nucleic Acid Res 1995; 23(7): 1197-1203.
    • (1995) Nucleic Acid Res , vol.23 , Issue.7 , pp. 1197-1203
    • Bonham, M.A.1    Brown, S.2    Boyd, A.L.3
  • 103
    • 0029833815 scopus 로고    scopus 로고
    • A simple method for delivering morpholino antisense oligos into the cytoplasm of cells
    • Pardridge M, Vincent A, Matthews P. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev 1996; 6(3): 169-175.
    • (1996) Antisense Nucleic Acid Drug Dev , vol.6 , Issue.3 , pp. 169-175
    • Pardridge, M.1    Vincent, A.2    Matthews, P.3
  • 104
    • 0031754150 scopus 로고    scopus 로고
    • Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
    • Pooga M, Soomets U, Hallbrink M, et al. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat Biotechnol 1998; 16(9): 857-861.
    • (1998) Nat Biotechnol , vol.16 , Issue.9 , pp. 857-861
    • Pooga, M.1    Soomets, U.2    Hallbrink, M.3
  • 106
    • 0038688782 scopus 로고    scopus 로고
    • Antisense oligonucleotides for cancer therapy-an overview
    • Stahel RA, Zangemeister-Wittke U. Antisense oligonucleotides for cancer therapy-an overview. Lung Cancer 2003; 41(Suppl 1): 81-88.
    • (2003) Lung Cancer , vol.41 , Issue.SUPPL. 1 , pp. 81-88
    • Stahel, R.A.1    Zangemeister-Wittke, U.2
  • 107
    • 0027223428 scopus 로고
    • The effect of transforming growth factor-beta 2-specific phosphorothioateantisense oligodeoxynucleotide in reversing cellular immunosuppression in malignant glioma
    • Jachimczak P, Bogdahn U, Behl C, et al. The effect of transforming growth factor-beta 2-specific phosphorothioateantisense oligodeoxynucleotide in reversing cellular immunosuppression in malignant glioma. J Neurosurg 1993; 78: 944-951.
    • (1993) J Neurosurg , vol.78 , pp. 944-951
    • Jachimczak, P.1    Bogdahn, U.2    Behl, C.3
  • 108
    • 0030021142 scopus 로고    scopus 로고
    • Transforming growth factor-beta mediated autocrine growth regulation of gliomas with phosphorothioate antisense oligonucleotides
    • Jachimczak P, Hessdorfer B, Fabel-Schulte K, et al. Transforming growth factor-beta mediated autocrine growth regulation of gliomas with phosphorothioate antisense oligonucleotides. Int J Cancer 1996; 65(3): 332-337.
    • (1996) Int J Cancer , vol.65 , Issue.3 , pp. 332-337
    • Jachimczak, P.1    Hessdorfer, B.2    Fabel-Schulte, K.3
  • 109
    • 22044456529 scopus 로고    scopus 로고
    • Intracerebral and intrathecal infusion of the TGF-β2-specific antisense phosphorotioate oligonucleotide AP 12009 in rabbits and primates: Toxicology and safety
    • Schlingensiepen R, Goldbrunner M, Szyrach MNI, et al. Intracerebral and intrathecal infusion of the TGF-β2-specific antisense phosphorotioate oligonucleotide AP 12009 in rabbits and primates: Toxicology and safety. Oligonucleotides 2005; 15: 94-104.
    • (2005) Oligonucleotides , vol.15 , pp. 94-104
    • Schlingensiepen, R.1    Goldbrunner, M.2    Szyrach, M.N.I.3
  • 111
    • 34547187636 scopus 로고    scopus 로고
    • Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: From preclinical to phase I/II studies
    • Hau P, Jachimczak P, Schlingensiepen R, et al. Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: From preclinical to phase I/II studies. Oligonucleotides 2007; 17(2): 201-212.
    • (2007) Oligonucleotides , vol.17 , Issue.2 , pp. 201-212
    • Hau, P.1    Jachimczak, P.2    Schlingensiepen, R.3
  • 112
    • 41949094382 scopus 로고    scopus 로고
    • Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles
    • Schneider T, Becker A, Ringe K, et al. Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles. J Neuroimmunol 2008; 195(1-2): 21-27.
    • (2008) J Neuroimmunol , vol.195 , Issue.1-2 , pp. 21-27
    • Schneider, T.1    Becker, A.2    Ringe, K.3
  • 113
    • 0032566005 scopus 로고    scopus 로고
    • Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA
    • Kondo S, Kondo Y, Li G, Silverman RH, Cowell JK. Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA. Oncogene 1998; 16(25): 3323-3330.
    • (1998) Oncogene , vol.16 , Issue.25 , pp. 3323-3330
    • Kondo, S.1    Kondo, Y.2    Li, G.3    Silverman, R.H.4    Cowell, J.K.5
  • 114
    • 0031750443 scopus 로고    scopus 로고
    • Antisense telomerase treatment: Induction of two distinct pathways, apoptosis and differentiation
    • Kondo S, Tanaka Y, Kondo Y, et al. Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation. FASEB J 1998; 12(10): 801-811.
    • (1998) FASEB J , vol.12 , Issue.10 , pp. 801-811
    • Kondo, S.1    Tanaka, Y.2    Kondo, Y.3
  • 115
    • 0034496406 scopus 로고    scopus 로고
    • Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53
    • Komata T, Kondo Y, Koga S, Lo SC, Chung LWK, Kondo S. Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53. Gene Ther 2000; 7(24): 2071-2079.
    • (2000) Gene Ther , vol.7 , Issue.24 , pp. 2071-2079
    • Komata, T.1    Kondo, Y.2    Koga, S.3    Lo, S.C.4    Chung, L.W.K.5    Kondo, S.6
  • 116
    • 0034662616 scopus 로고    scopus 로고
    • 2-5A antisense telomerase RNA therapy for intracranial malignant gliomas
    • Mukai S, Kondo Y, Koga S, Komata T, Barna BP, Kondo S. 2-5A antisense telomerase RNA therapy for intracranial malignant gliomas. Cancer Res 2000; 60(16): 4461-4467.
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4461-4467
    • Mukai, S.1    Kondo, Y.2    Koga, S.3    Komata, T.4    Barna, B.P.5    Kondo, S.6
  • 117
    • 38449091201 scopus 로고    scopus 로고
    • Combined effect of 2-5A-linked antisense against telomerase RNA and conventional therapies on human malignant glioma cells in vitro and in vivo
    • Iwado E, Daido S, Kondo Y, Kondo S. Combined effect of 2-5A-linked antisense against telomerase RNA and conventional therapies on human malignant glioma cells in vitro and in vivo. Int J Oncol 2007; 31(5): 1087-1095.
    • (2007) Int J Oncol , vol.31 , Issue.5 , pp. 1087-1095
    • Iwado, E.1    Daido, S.2    Kondo, Y.3    Kondo, S.4
  • 118
    • 14644438523 scopus 로고    scopus 로고
    • Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-α delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas
    • Grossman SA, Alavi JB, Supko JG, et al. Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-α delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas. NeuroOncol 2004; 6: 32-40.
    • (2004) NeuroOncol , vol.6 , pp. 32-40
    • Grossman, S.A.1    Alavi, J.B.2    Supko, J.G.3
  • 119
    • 0033555551 scopus 로고    scopus 로고
    • Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
    • McKay RA, Miraglia LJ, Cummins LL, et al. Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J Biol Chem 1999; 3: 1715-1722.
    • (1999) J Biol Chem , vol.3 , pp. 1715-1722
    • McKay, R.A.1    Miraglia, L.J.2    Cummins, L.L.3
  • 120
    • 0033969883 scopus 로고    scopus 로고
    • Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner
    • Potapova O, Gorospe M, Dougherty RH, et al. Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner. Mol Cell Biol 2000; 20(5): 1713-1722.
    • (2000) Mol Cell Biol , vol.20 , Issue.5 , pp. 1713-1722
    • Potapova, O.1    Gorospe, M.2    Dougherty, R.H.3
  • 121
    • 12644268252 scopus 로고    scopus 로고
    • Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
    • Monia BP, Sasmor H, Johnston J, et al. Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc Natl Acad Sci USA 1996; 93(26): 15481-15484.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.26 , pp. 15481-15484
    • Monia, B.P.1    Sasmor, H.2    Johnston, J.3
  • 122
    • 0029903628 scopus 로고    scopus 로고
    • Antisense oligonucleotides demonstrate a dominant role of c-Ki-RAS proteins in regulating the proliferation of diploid human fibroblasts
    • Chen G, Oh S, Monia BP, Stacey DW. Antisense oligonucleotides demonstrate a dominant role of c-Ki-RAS proteins in regulating the proliferation of diploid human fibroblasts. J Biol Chem 1996; 271(45): 28259-28265.
    • (1996) J Biol Chem , vol.271 , Issue.45 , pp. 28259-28265
    • Chen, G.1    Oh, S.2    Monia, B.P.3    Stacey, D.W.4
  • 123
    • 0033557535 scopus 로고    scopus 로고
    • Antiangiogenesis treatment for gliomas: Transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo
    • Im SA, Gomez-Manzano C, Fueyo J, et al. Antiangiogenesis treatment for gliomas: Transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res 1999; 59: 895-900.
    • (1999) Cancer Res , vol.59 , pp. 895-900
    • Im, S.A.1    Gomez-Manzano, C.2    Fueyo, J.3
  • 124
    • 0028271497 scopus 로고
    • Rat glioblastoma cells expressing an antisense RNA to the insuline-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors
    • Resnicoff M, Sell C, Rubini M, et al. Rat glioblastoma cells expressing an antisense RNA to the insuline-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. Cancer Res 1994; 54(8): 2218-2222.
    • (1994) Cancer Res , vol.54 , Issue.8 , pp. 2218-2222
    • Resnicoff, M.1    Sell, C.2    Rubini, M.3
  • 125
    • 0035871490 scopus 로고    scopus 로고
    • Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insuline-like growth factor type I receptor in malignant astrocytomas
    • Andrews DW, Resnicoff M, Flanders AE, et al. Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insuline-like growth factor type I receptor in malignant astrocytomas. J Clin Oncol 2001; 19(8): 2189-2200.
    • (2001) J Clin Oncol , vol.19 , Issue.8 , pp. 2189-2200
    • Andrews, D.W.1    Resnicoff, M.2    Flanders, A.E.3
  • 126
    • 34248136479 scopus 로고    scopus 로고
    • Inhibition of both adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo
    • Liu TJ, La Fortune T, Honda T, et al. Inhibition of both adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo. Mol Cancer Ther 2007; 6: 1357-1367.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1357-1367
    • Liu, T.J.1    La Fortune, T.2    Honda, T.3
  • 127
    • 33747837804 scopus 로고    scopus 로고
    • Antisense oligonucleodes targeting the focal adhesion kinase inhibit proliferation, induce apoptosis and cooperate with cytotoxic drugs in human glioma cells
    • Wu ZM, Yuan XH, Jiang PC, Li ZQ, Wu T. Antisense oligonucleodes targeting the focal adhesion kinase inhibit proliferation, induce apoptosis and cooperate with cytotoxic drugs in human glioma cells. J NeuroOncol 2006; 77(2): 117-123.
    • (2006) J NeuroOncol , vol.77 , Issue.2 , pp. 117-123
    • Wu, Z.M.1    Yuan, X.H.2    Jiang, P.C.3    Li, Z.Q.4    Wu, T.5
  • 128
    • 0036830240 scopus 로고    scopus 로고
    • PTEN suppresses hyaluronic acid-induced matrix metalloproteinases-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphrylation
    • Park MJ, Kim MS, Park IC, et al. PTEN suppresses hyaluronic acid-induced matrix metalloproteinases-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphrylation. Cancer Res 2002; 62: 6318-6322.
    • (2002) Cancer Res , vol.62 , pp. 6318-6322
    • Park, M.J.1    Kim, M.S.2    Park, I.C.3
  • 129
    • 30944467414 scopus 로고    scopus 로고
    • The effects of antisense AKT2 RNA on the inhibition of malignant glioma cell growth in vitro and in vivo
    • Pu P, Kang C, Li J, Jiang H, Cheng J. The effects of antisense AKT2 RNA on the inhibition of malignant glioma cell growth in vitro and in vivo. J NeuroOncol 2006; 76: 1-11.
    • (2006) J NeuroOncol , vol.76 , pp. 1-11
    • Pu, P.1    Kang, C.2    Li, J.3    Jiang, H.4    Cheng, J.5
  • 130
    • 33644836724 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumors
    • Halatsch ME, Schmidt U, Behnke-Mursch J, Unterberg A, Rainer Wirtz C. Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumors. Cancer Treat Rev 2006; 32: 74-89.
    • (2006) Cancer Treat Rev , vol.32 , pp. 74-89
    • Halatsch, M.E.1    Schmidt, U.2    Behnke-Mursch, J.3    Unterberg, A.4    Rainer Wirtz, C.5
  • 131
    • 33646592855 scopus 로고    scopus 로고
    • c-Met antisense oligodeoxynucleotide inhibits growth of glioma cells
    • Chu S, Yuan X, Li Z, Jiang P, Zhang J. c-Met antisense oligodeoxynucleotide inhibits growth of glioma cells. Surg Neurol 2006; 65: 533-538.
    • (2006) Surg Neurol , vol.65 , pp. 533-538
    • Chu, S.1    Yuan, X.2    Li, Z.3    Jiang, P.4    Zhang, J.5
  • 132
    • 33750352906 scopus 로고    scopus 로고
    • in vitro and in vivo Potentiating the cytotoxic effect of radiation on human U251 gliomas by the c-Met antisense oligodeoxynucleotides
    • Chu S, Zhu Z, Yuan X, Li Z, Jiang P. in vitro and in vivo Potentiating the cytotoxic effect of radiation on human U251 gliomas by the c-Met antisense oligodeoxynucleotides. J Neurooncol 2006; 80(2): 143-149.
    • (2006) J Neurooncol , vol.80 , Issue.2 , pp. 143-149
    • Chu, S.1    Zhu, Z.2    Yuan, X.3    Li, Z.4    Jiang, P.5
  • 133
    • 34447257100 scopus 로고    scopus 로고
    • c-Met antisense oligonucleotides as a novel therapeutic agent for glioma: in vitro and in vivo Studies of uptake, effects, and toxicity
    • Chu S, Zang H, Ma Y, et al. c-Met antisense oligonucleotides as a novel therapeutic agent for glioma: in vitro and in vivo Studies of uptake, effects, and toxicity. J Surg Res 2007; 141(2): 284-288.
    • (2007) J Surg Res , vol.141 , Issue.2 , pp. 284-288
    • Chu, S.1    Zang, H.2    Ma, Y.3
  • 134
    • 2442701602 scopus 로고    scopus 로고
    • Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro
    • Khazenzon NM, Ljubimov AV, Lakhter AJ, et al. Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro. Mol Cancer Ther 2003; 2(10): 985-994.
    • (2003) Mol Cancer Ther , vol.2 , Issue.10 , pp. 985-994
    • Khazenzon, N.M.1    Ljubimov, A.V.2    Lakhter, A.J.3
  • 135
    • 0030899731 scopus 로고    scopus 로고
    • in vitro Inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor
    • Mohanam S, Chintala SK, Go Y, et al. in vitro Inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor. Oncogene 1997; 14(11): 1351-1359.
    • (1997) Oncogene , vol.14 , Issue.11 , pp. 1351-1359
    • Mohanam, S.1    Chintala, S.K.2    Go, Y.3
  • 136
    • 0036850631 scopus 로고    scopus 로고
    • Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides
    • Dias N, Stein CA. Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides. Eur J Pharm Biopharm 2000; 54: 263-269.
    • (2000) Eur J Pharm Biopharm , vol.54 , pp. 263-269
    • Dias, N.1    Stein, C.A.2
  • 137
    • 0034068054 scopus 로고    scopus 로고
    • Antisense-mediated inhibition of the bcl-2 gene induces apoptosis in human malignant glioma
    • Julien T, Frankel B, Longo S, et al. Antisense-mediated inhibition of the bcl-2 gene induces apoptosis in human malignant glioma. Surg Neurol 2000; 53(4): 360-369.
    • (2000) Surg Neurol , vol.53 , Issue.4 , pp. 360-369
    • Julien, T.1    Frankel, B.2    Longo, S.3
  • 138
    • 0036730430 scopus 로고    scopus 로고
    • Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells
    • Guensberg P, Wacheck V, Lucas T, et al. Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells. Chemotherapy 2002; 48(4): 189-195.
    • (2002) Chemotherapy , vol.48 , Issue.4 , pp. 189-195
    • Guensberg, P.1    Wacheck, V.2    Lucas, T.3
  • 139
    • 77951108656 scopus 로고    scopus 로고
    • Zalewski, A., Shi, Y.: US20006133242 (2000)
    • Zalewski, A., Shi, Y.: US20006133242 (2000).
  • 140
    • 77951120162 scopus 로고    scopus 로고
    • Bandman, O., Corley, N.C., Guegler, K.J.: US20016303765 (2001)
    • Bandman, O., Corley, N.C., Guegler, K.J.: US20016303765 (2001).
  • 141
    • 77951119441 scopus 로고    scopus 로고
    • Schlingensiepen, G.F., Brysch, W., Schlingensiepen, K.H.: US20026455689 (2002)
    • Schlingensiepen, G.F., Brysch, W., Schlingensiepen, K.H.: US20026455689 (2002).
  • 142
    • 77951142370 scopus 로고    scopus 로고
    • Baker, B.F., Cowsert, L.M.: US20030105044 (2003)
    • Baker, B.F., Cowsert, L.M.: US20030105044 (2003).
  • 143
    • 77951114316 scopus 로고    scopus 로고
    • McKay, R., Dean, N., Monia, B., Nero, P., Gaarde, W.A.: US20040029823A1 (2004)
    • McKay, R., Dean, N., Monia, B., Nero, P., Gaarde, W.A.: US20040029823A1 (2004).
  • 144
    • 77951127582 scopus 로고    scopus 로고
    • Khare, R., Elliott, V.S., Marquis, S.P.: US20070124581 (2007)
    • Khare, R., Elliott, V.S., Marquis, S.P.: US20070124581 (2007).
  • 145
    • 77951127310 scopus 로고    scopus 로고
    • Grandis, J.R.: US2008234181A1 (2008)
    • Grandis, J.R.: US2008234181A1 (2008).
  • 147
    • 77951144042 scopus 로고    scopus 로고
    • Schlingensiepen, K.H., Schlingensiepen, R.: MX2007007184 (2008)
    • Schlingensiepen, K.H., Schlingensiepen, R.: MX2007007184 (2008).
  • 148
    • 77951113098 scopus 로고    scopus 로고
    • Adwan, H.: US2009017103A1 (2009)
    • Adwan, H.: US2009017103A1 (2009).
  • 149
    • 77951123479 scopus 로고    scopus 로고
    • Beri, R.: EP2025752 (2009)
    • Beri, R.: EP2025752 (2009).
  • 151
    • 77951131220 scopus 로고    scopus 로고
    • C. IL-8 and prostaglandin E synthase expression in low and high grade human glioma
    • Milan, June
    • Venza M, Caffo M, Caruso G, et al. C. IL-8 and prostaglandin E synthase expression in low and high grade human glioma. Molecular Mechanisms in Neuroscience. Milan, June 2008.
    • (2008) Molecular Mechanisms in Neuroscience
    • Venza, M.1    Caffo, M.2    Caruso, G.3


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