Antisense oligonucleodes targeting the focal adhesion kinase inhibit proliferation, induce apoptosis and cooperate with cytotoxic drugs in human glioma cells

Journal of Neuro-Oncology

Volumn 77, Issue 2, 2006, Pages 117-123

  Wu, Zhi Min ^a   Yuan, Xian Hou ^a   Jiang, Pu Cha ^a   Li, Zhi Qiang ^a   Wu, Tao ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Apoptosis; Focal adhesion kinase; Human glioma cells; Proliferation

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; CASPASE 3 INHIBITOR; CISPLATIN; CYTOTOXIC AGENT; ETOPOSIDE; FOCAL ADHESION KINASE; NIMUSTINE; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASPASE;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SPECTROFLUOROMETRY; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING; BRAIN TUMOR; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; GLIOMA; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SYNERGISM; FLOW CYTOMETRY; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; OLIGONUCLEOTIDES, ANTISENSE; TRANSFECTION;

EID: 33747837804     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-005-9025-9     Document Type: Article

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