A simple method for delivering Molpholino antisense oligos into the cytoplasm of cells

Antisense and Nucleic Acid Drug Development

Volumn 6, Issue 3, 1996, Pages 169-175

  Partridge, Michael ^a   Vincent, Alexandra ^a   Matthews, Paula ^a   Puma, John ^a   Stein, David ^a   Summerton, James ^a  

^a Antivirals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL TRANSPORT; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; GENE SEQUENCE; GENE TARGETING; HELA CELL; HUMAN; HUMAN CELL; LABORATORY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029833815     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1996.6.169     Document Type: Article

References (8)

1. ANTIVIRALS Inc. Technical Report 2. (1993). Comparative studies of translation inhibition in reticulocyte lysates. Antisense Res. Dev. 3(1), Technical Reports 2, following page 153.
2. ANTIVIRALS Inc. Technical Report 3. (1993). Comparative studies of efficacy and specificity of translation inhibition in reticulocyte lysates. Antisense Res. Dev. 3(3), Technical Reports 3, following page 306.
3. BENNETT, M., and SCHWARTZ, S. (1995). Antisense therapy for angioplasty restenosis: Some critical considerations. Circulation 92, 1981-1993.
4. BENNETT, R. (1993). As nature intended? The uptake of DNA and oligonucleotides by eucaryotic cells. Antisense Res. Dev. 3, 235-241.
5. BENNETT, R., CONDON, T.P., GRIMM, S., CHAN, H., and CHIANG, M.-Y. (1994). Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J. Immunol. 152, 3530-3540.
6. BONHAM, M., BROWN, S., BOYD, A., BROWN, P., BRUCKENSTEIN, D., HANVEY, J., THOMSON, S., PIPE, A., HASSMAN, F., BISI, J., FROEHLER, B., MATTEUCCI, M., WAGNER, R., NOBLE, S., and BABISS, L. (1995). An assessment of the antisense properties of Rnase H-competent and steric-blocking oligomers. Nucleic Acids Res. 23, 1197-1203.
7. COLIGE, A., SOKOLOV, B.P., NUGENT, P., BASERGA, R., and PROCKOP, D.J. (1993). Use of an antisense oligonucleotide to in hibit expression of a mutated human procollagen gene (COL1A1) in transfected mouse 3T3 cells. Biochemistry 32, 7-11.
8. WAGNER, R., MATTEUCCI, M., LEWIS, J., GUTIERREZ, A., MOULDS, C., and FROEHLER, B. (1993). Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science 260, 1510-1513.