Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference

Biomaterials

Volumn 28, Issue 8, 2007, Pages 1565-1571

  Tan, Wee Beng ^a   Jiang, Shan ^a   Zhang, Yong ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chitosan; Fluorescence; Gene therapy; Nanoparticle

Indexed keywords

GENE SILENCING; GENE THERAPY; MAMMALIAN CELLS; SHORT INTERFERING RNA (SIRNA);

CHITIN; FLUORESCENCE; GENES; GENETIC ENGINEERING; RNA; SEMICONDUCTOR QUANTUM DOTS;

NANOSTRUCTURED MATERIALS;

CHITOSAN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2 ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; LUCIFERASE; MOLECULAR MARKER; NANOPARTICLE; QUANTUM DOT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; GENE CONSTRUCT; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; NANOENCAPSULATION; NONVIRAL GENE DELIVERY SYSTEM; ONCOGENE NEU; PRIORITY JOURNAL; RNA INTERFERENCE;

BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; GENE SILENCING; GENE TARGETING; HUMANS; QUANTUM DOTS; RECEPTOR, ERBB-2; RNA INTERFERENCE;

MAMMALIA;

EID: 33845975678     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.11.018     Document Type: Article

References (41)

1. Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., and Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 6836 (2001) 494-498
2. Hannon G.J. RNA interference. Nature 418 6894 (2002) 244-251
3. Martinez J., Patkaniowska A., Urlaub H., Luhrmann R., and Tuschl T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 5 (2002) 563-574
4. Sharp P.A. RNAi and double-strand RNA. Genes Dev 13 2 (1999) 139-141
5. Zamore P.D., Tuschl T., Sharp P.A., and Bartel D.P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21-23 nucleotide intervals. Cell 101 1 (2000) 25-33
6. Novina C.D., and Sharp P.A. The RNAi revolution. Nature 430 6996 (2004) 161-164
7. Tuschl T., Zamore P.D., Lehmann R., Bartel D.P., and Sharp P.A. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 13 24 (1999) 3191-3197
8. Achenbach T.V., Brunner B., and Heermeier K. Oligonucleotide-based knockdown technologies: antisense versus RNA interference. Chembiochem 4 10 (2003) 928-935
9. Devi G.R. siRNA-based approaches in cancer therapy. Cancer Gene Ther 13 9 (2006) 819-829
10. Tiscornia G., Singer O., Ikawa M., and Verma I.M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Nat Acad Sci USA 100 4 (2003) 1844-1848
11. Qin X.F., An D.S., Chen I.S.Y., and Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Nat Acad Sci USA 100 1 (2003) 183-188
12. Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003;9(4):493-501.
13. Xu D., McCarty D., Fernandes A., Fisher M., Samulski R.J., and Juliano R.L. Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector. Mol Ther 11 4 (2005) 523-530
14. Tomar R.S., Matta H., and Chaudhary P.M. Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene 22 36 (2003) 5712-5715
15. Kronke J., Kittler R., Buchholz F., Windisch M.P., Pietschmann T., Bartenschlager R., et al. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol 78 7 (2004) 3436-3446
16. Yang G., Thompson J.A., Fang B.L., and Liu J.S. Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumorgrowth in a model of human ovarian cancer. Oncogene 22 36 (2003) 5694-5701
17. Hannon G.J., and Rossi J.J. Unlocking the potential of the human genome with RNA interference. Nature 431 7006 (2004) 371-378
18. Clayton J. The silent treatment. Nature 431 7008 (2004) 599
19. Sioud M., and Sorensen D.R. Cationic liposome-mediated delivery of siRNAs in adult mice. Biochem Biophys Res Commun 312 4 (2003) 1220-1225
20. Sorensen D.R., Leirdal M., and Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 327 4 (2003) 761-766
21. Muratovska A., and Eccles M.R. Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett 558 1-3 (2004) 63-68
22. Urban-Klein B., Werth S., Abuharbeid S., Czubayko F., and Aigner A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther 12 5 (2005) 461-466
23. Chiu S.H., Ueno N.T., and Lee R.J. Tumor-targeted gene delivery via anti-HER2 antibody (trastuzumab, Herceptin (R)) conjugated polyethylemmine. J Control Release 97 2 (2004) 357-369
24. Schiffelers R.M., Mixson A.J., Ansari A.M., Fens M., Tang Q.Q., Zhou Q., et al. Transporting silence: design of carriers for siRNA to angiogenic endothelium. J Control Release 109 1-3 (2005) 5-14
25. Chowdhury E.H., and Akaike T. Bio-functional inorganic materials: an attractive branch of gene-based nano-medicine delivery for 21st century. Curr Gene Ther 5 6 (2005) 669-676
26. Khaled A., Guo S.C., Li F., and Guo P.X. Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology. Nano Lett 5 9 (2005) 1797-1808
27. Dunne J., Drescher B., Riehle H., Hadwiger P., Young B.D., Krauter J., et al. The apparent uptake of fluorescently labeled siRNAs by electroporated cells depends on the fluorochrome. Oligonucleotides 13 5 (2003) 375-380
28. Wilson J.A., Jayasena S., Khvorova A., Sabatinos S., Rodrigue-Gervais I.G., Arya S., et al. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Nat Acad Sci USA 100 5 (2003) 2783-2788
29. Lewis D.L., and Wolff J.A. Delivery of siRNA and siRNA expression constructs to adult mammals by hydrodynamic intravascular injection. Methods Enzymol 392 (2005) 336-350
30. Thomas M., Lu J.J., Ge Q., Zhang C.C., Chen J.Z., and Klibanov A.M. Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. Proc Nat Acad Sci USA 102 16 (2005) 5679-5684
31. Alivisatos A.P. Semiconductor clusters, nanocrystals, and quantum dots. Science 271 5251 (1996) 933-937
32. Bruchez M., Moronne M., Gin P., Weiss S., and Alivisatos A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 281 5385 (1998) 2013-2016
33. Chan W.C.W., and Nie S.M. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 281 5385 (1998) 2016-2018
34. Chan W.C.W., Maxwell D.J., Gao X.H., Bailey R.E., Han M.Y., and Nie S.M. Luminescent quantum dots for multiplexed biological detection and imaging. Curr Opin Biotechnol 13 1 (2002) 40-46
35. Lee L.Y., Ong S.L., Hu J.Y., Ng W.J., Feng Y.Y., Tan X.L., et al. Use of semiconductor quantum dots for photostable immunofluorescence labeling of Cryptosporidium parvum. Appl Environ Microbiol 70 10 (2004) 5732-5736
36. Yang X.T., and Zhang Y. Encapsulation of quantum nanodots in polystyrene and silica micro-/nanoparticles. Langmuir 20 14 (2004) 6071-6073
37. Hynes N.E., and Stern D.F. The biology of Erbb-2 Neu Her-2 and its role in cancer. Biochim Biophys Acta 1198 2-3 (1994) 165-184
38. Slamon D.J., Godolphin W., Jones L.A., Holt J.A., Wong S.G., Keith D.E., et al. Studies of the Her-2/Neu proto-oncogene in human-breast and ovarian cancer. Science 244 4905 (1989) 707-712
39. Choudhury A., Charo J., Parapuram S.K., Hunt R.C., Hunt D.M., Seliger B., et al. Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines. Int J Cancer 108 1 (2004) 71-77
40. Yarden Y. Biology of HER2 and its importance in breast cancer. Oncology 61 (2001) 1-13
41. Lewis G.D., Figari I., Fendly B., Wong W.L., Carter P., Gorman C., et al. Differential responses of human tumor-cell lines to anti-P185(Her2) monoclonal antibodies. Cancer Immunol Immunother 37 4 (1993) 255-263