Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53

Gene Therapy

Volumn 7, Issue 24, 2000, Pages 2071-2079

  Komata, T ^a,b   Kondo, Y ^a,b   Koga, S ^a,c   Ko, S C ^d   Chung, L W K ^d   Kondo, S ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

2 5A antisense; Apoptosis; Gene therapy; P53; Telomerase

Indexed keywords

2',5' OLIGOADENYLIC ACID; ANTISENSE OLIGONUCLEOTIDE; CASPASE; PROTEIN P16; PROTEIN P21; PROTEIN P53; RNA; TELOMERASE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASTROCYTE; CANCER GROWTH; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE MUTATION; GENE THERAPY; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CENTRAL NERVOUS SYSTEM NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; FLOW CYTOMETRY; GENE THERAPY; GENES, P16; GENES, P53; GENETIC VECTORS; GLIOMA; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; RNA, ANTISENSE; TELOMERASE; TUMOR CELLS, CULTURED;

ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; MUS MUSCULUS;

EID: 0034496406     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301327     Document Type: Article

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