Mixed backbone antisense oligonucleotides: Design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments

Nucleic Acids Research

Volumn 25, Issue 2, 1997, Pages 370-378

  Kandimalla, Ekambar R ^a   Manning, Adrienne ^a   Zhao, Qiuyan ^a   Shaw, Denise R ^b   Byrn, Randal A ^c   Sasisekharan, V ^d   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

^b University of Alabama at Birmingham   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NUCLEASE S1; OLIGODEOXYRIBONUCLEOTIDE; PHOSPHODIESTERASE; PHOSPHOROTHIOIC ACID; RIBONUCLEOSIDE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CIRCULAR DICHROISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ASPERGILLUS NUCLEASE S1; CELL DIVISION; CELLS, CULTURED; CIRCULAR DICHROISM; COMPLEMENT SYSTEM PROTEINS; DNA, ANTISENSE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENES, GAG; HIV-1; MICE; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGORIBONUCLEOTIDES; PARTIAL THROMBOPLASTIN TIME; PHOSPHODIESTERASE I; PHOSPHORIC DIESTER HYDROLASES; RIBONUCLEASE H, CALF THYMUS; RNA, ANTISENSE; SPECTROPHOTOMETRY; SPLEEN;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; SERPENTES;

EID: 0030860258     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.2.370     Document Type: Article

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