A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model

Cancer Research

Volumn 60, Issue 5, 2000, Pages 1197-1201

  Needham, David ^a   Anyarambhatla, Gopal ^a   Kong, Garheng ^a   Dewhirst, Mark W ^b  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; LIPOSOME; PHOSPHOLIPID;

ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; HUMAN CELL; HYPERTHERMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TEMPERATURE SENSITIVITY; THERMAL ANALYSIS; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; HYPERTHERMIA, INDUCED; LIPOSOMES; MICE; NEOPLASMS, EXPERIMENTAL; TEMPERATURE;

EID: 0034161921     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Jain, R. K. Barriers to drug delivery in solid tumors. Sci. Am., 271: 58-65, 1994.
2. Needham, D. Materials engineering of lipid bilayers for drug carrier function. MRS Bull., 24: 32-40, 1999.
3. Allen, T. M. Liposomes: opportunities in drug delivery. Drugs, 54: 8-14, 1997.
4. Gabizon, A., and Barenholtz, Y. Liposomal anthracyclins. From basics to clinical approval of PEGylated liposomal doxorubicin. In: A. Janoff (ed.), Liposomes: Rational Design, pp. 343-362. New York: Marcel Dekker, Inc., 1999.
5. Campos, S., and Shapiro, C. Clinical evaluation of liposomal anthracyclins. In: A. Janoff (ed.), Liposomes: Rational Design, pp. 363-377. New York: Marcel Dekker, Inc., 1999.
6. Yatvin, M. B., Weinstein, J. N., Dennis, W. H., and Blumenthal, R. Design of liposomes for enhanced local release of drugs by hyperthermia. Science (Washington DC), 202: 1290-1293, 1978.
7. Kong, G., and Dewhirst, M. W. Hyperthermia and liposomes: a review. Int. J. Hyperthermia, 15: 345-370, 1999.
8. Gaber, M. H., Ning, Z. W., Hong, K., Huang, S. K., Dewhirst, M., and Papahadjopoulos, D. Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks. Int. J. Radiat. Oncol. Biol. Phys., 36: 1177-1187, 1996.
9. Gaber, M. H., Hong, K., Huang, S. K., and Papahadjopoulos, D. Thermosensitive sterically stabilized liposomes: formulation and in vitro studies on mechanism of doxorubicin release by bovine serum and human plasma. Pharmacol. Res., 12: 1407-1416, 1995.
10. Hope, M. J., Bally, M. B., Webb, G., and Cullis, P. R. Production of large unilamellar vesicles by a rapid extrusion procedure, characterization of size, trapped volume and ability to maintain a membrane potential. Biochim. Biophys. Acta, 812: 55-65, 1985.
11. Mayer, L. D., Bally, M. B., Hope, M. J., and Cullis, P. R. Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochim. Biophys. Acta. 816: 294-302, 1985.
12. Maruyama, K., Unezaki, S., Takahashi, N., and Iwatsuru, M. Enhanced delivery of doxorubicin to tumor by long-circulating thermosensitive liposomes and local hyperthermia. Biochim. Biophys. Acta, 1149: 209-216, 1993.
13. Hauck, M. L., Dewhirst, M. W., Bigner, D. D., and Zalutsky, M. L. Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model. Clin. Cancer Res., 3: 63-70, 1997.
14. Leopold, K. A., Oleson, J. R., Clarke-Pearson, D., Soper, J., Berchuck, A., Samulski, T. V., Page, R. L., Blivin, J., Tomberlin, J. K., and Dewhirst, M. W. Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma. Int. J. Radiat. Oncol. Biol. Phys., 27: 1245-1251, 1993.
15. Anscher, M. S., Samulski, T. V., Rosner, G., Dodge, R., Prosnitz, L., and Dewhirst, M. W. Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate. Int. J. Radiat. Oncol. Biol. Phys., 37: 1059-1065, 1997.
16. Papahadjopoulos, D., Jacobsen, K., Nir, S., and Isac, T. Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effects of temperature and cholesterol. Biochim. Biophys. Acta, 311: 330-348, 1973.
17. Mouritsen, O. G., Jorgensen, K., and Honger, T. Permeability of lipid bilayers near the phase transition. In: E. A. Disalvo and S. A. Simon (ed.), Permeability and Stability of Lipid Bilayers, pp. 137-160. Boca Raton, FL: CRC Press, 1995.
18. Anyarambhatla, G. R., and Needham, D. Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: a new temperature-sensitive liposome for use with mild hyperthermia. J. Liposome Res., 9: 491-506, 1999.
19. Needham, D., and Zhelev, D. V. Lysolipid exchange with lipid vesicle membranes. Ann. Biomed. Eng., 23: 287-298, 1995.
20. Needham, D., Stoicheva, N., and Zhelev, D. V. Exchange of monooleoylphosphatidycholine as monomer and micelle with membranes containing grafted polyethyleneglycol. Biophys. J., 73: 2615-2629, 1997.
21. Stewart, C. F., and Ratain, M. J. In: V.T. DeVita, S. H. Rosenberg, and S.A. Rosenberg (ed.), Cancer: Principles & Practice of Oncology, pp. 461-465. Philadelphia, PA: Lippincott-Raven, Inc., 1997.
22. Lasic, D. D. Doxorubicin in sterically stabilized liposomes. Nature (Lond.), 380: 561-562, 1996.
23. Vaupel, P., and Jain, R. Tumor blood supply and metabolic microenvironment. Stuttgart: Verlag, 1991.
24. Cummings, J., and McArdle, C. Studies on the in rivo disposition of Adriamycin in human tumours which exhibit different responses to the drug. Br. J. Cancer, 53: 835-838, 1986.