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Volumn 41, Issue SUPPL. 1, 2003, Pages 81-88

Antisense oligonucleotides for cancer therapy - An overview

Author keywords

Antisense; Cancer; Oligonucleotide

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BCR ABL PROTEIN; CGP 69846A; CLUSTERIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENE EXPRESSION MODULATOR 231; GTI 2040; INX 3001; ISIS 2503; ISIS 3521; ISOENZYME; MG 98; OBLIMERSEN; OGX 011; PROTEIN; PROTEIN BCL 2; PROTEIN HA RAS; PROTEIN KINASE C ALPHA; PROTEOME; RAF PROTEIN; UNCLASSIFIED DRUG;

EID: 0038688782     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(03)00147-8     Document Type: Conference Paper
Times cited : (90)

References (48)
  • 1
    • 0036846993 scopus 로고    scopus 로고
    • Antisense therapy for cancer - The time of truth
    • Jansen B., Zangemeister-Wittke U. Antisense therapy for cancer - the time of truth. Lancet Oncol. 3:2002;672-683.
    • (2002) Lancet Oncol. , vol.3 , pp. 672-683
    • Jansen, B.1    Zangemeister-Wittke, U.2
  • 2
    • 0017670013 scopus 로고
    • Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
    • Paterson B.M., Roberts B.E., Kuff E.L. Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc. Natl. Acad. Sci. USA. 74:1977;4370-4374.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 4370-4374
    • Paterson, B.M.1    Roberts, B.E.2    Kuff, E.L.3
  • 3
    • 0041582974 scopus 로고
    • Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
    • Zamecnik P.C., Stephenson M.L. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA. 75:1978;280-284.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 280-284
    • Zamecnik, P.C.1    Stephenson, M.L.2
  • 4
    • 0030890649 scopus 로고    scopus 로고
    • Antisense oligonucleotidesas therapeutics for malignant diseases
    • Ho P.T.C., Parkinson D.R. Antisense oligonucleotidesas therapeutics for malignant diseases. Semin. Oncol. 24:1997;187-202.
    • (1997) Semin. Oncol. , vol.24 , pp. 187-202
    • Ho, P.T.C.1    Parkinson, D.R.2
  • 5
    • 0031922256 scopus 로고    scopus 로고
    • Molecular mechanisms of antisense drugs: RNase H
    • Crooke S.T. Molecular mechanisms of antisense drugs: RNase H. Antisense Nucleic Acid Drug Dev. 8:1998;133-134.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 133-134
    • Crooke, S.T.1
  • 6
    • 0029099305 scopus 로고
    • A new access to 2′-O-alkylated ribonucleosides and properties of 2′-O-alkylated oligoribonucleotides
    • Martin P. A new access to 2′-O-alkylated ribonucleosides and properties of 2′-O-alkylated oligoribonucleotides. Helvetica Chim. Acta. 78:1995;486-504.
    • (1995) Helvetica Chim. Acta , vol.78 , pp. 486-504
    • Martin, P.1
  • 7
    • 0034625010 scopus 로고    scopus 로고
    • Potent and nontoxic antisense oligonucleotides containing locked nucleic acids
    • Wahlestedt C., Salmi P., Good L., et al. Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc. Natl. Acad. Sci. USA. 97:2000;5633-5638.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5633-5638
    • Wahlestedt, C.1    Salmi, P.2    Good, L.3
  • 8
    • 0027168725 scopus 로고
    • Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
    • Monia B.P., Lesnik E.A., Gonzalez C., Lima W.F., McGee D., Guinosso C.J., et al. Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem. 268:1993;14514-14522.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14514-14522
    • Monia, B.P.1    Lesnik, E.A.2    Gonzalez, C.3    Lima, W.F.4    McGee, D.5    Guinosso, C.J.6
  • 9
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews D.H., Sabina J., Zuker M., Turner D.H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288:1999;911-940.
    • (1999) J. Mol. Biol. , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 10
    • 0030902471 scopus 로고    scopus 로고
    • Selecting effective antisense reagents on combinatorial oligonucleotide arrays
    • Milner N., Mir K.U., Southern E.M. Selecting effective antisense reagents on combinatorial oligonucleotide arrays. Nat. Biotechnol. 15:1997;537-541.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 537-541
    • Milner, N.1    Mir, K.U.2    Southern, E.M.3
  • 11
    • 0032566621 scopus 로고    scopus 로고
    • Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design
    • Tu G.C., Cao Q.N., Zhou F., Israel Y. Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design. J. Biol. Chem. 273:1998;25125-25131.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25125-25131
    • Tu, G.C.1    Cao, Q.N.2    Zhou, F.3    Israel, Y.4
  • 12
    • 0032833451 scopus 로고    scopus 로고
    • Antisense therapy of hematologic malignancies
    • Cotter F.E. Antisense therapy of hematologic malignancies. Semin. Hematol. 36:1999;9-14.
    • (1999) Semin. Hematol. , vol.36 , pp. 9-14
    • Cotter, F.E.1
  • 13
    • 0034015672 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
    • Waters J.S., Webb A., Cunningham D., et al. Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J. Clin. Oncol. 18:2000;1812-1823.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1812-1823
    • Waters, J.S.1    Webb, A.2    Cunningham, D.3
  • 14
    • 0032943134 scopus 로고    scopus 로고
    • Antisense therapeutics
    • Persidis A. Antisense therapeutics. Nat. Biotechnol. 17:1999;403-404.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 403-404
    • Persidis, A.1
  • 15
    • 0030987070 scopus 로고    scopus 로고
    • Reguation of protein kinase C
    • Newton A.C. Reguation of protein kinase C. Curr. Opin. Cell. Biol. 9:1997;161-167.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 161-167
    • Newton, A.C.1
  • 16
    • 0031963427 scopus 로고    scopus 로고
    • Antitumor activity of a PKC-alpha antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted into nude mice
    • Geiger T., Muller M., Dean N.M., Fabbro D. Antitumor activity of a PKC-alpha antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted into nude mice. Anticancer Drug Des. 13:1998;35-45.
    • (1998) Anticancer Drug Des. , vol.13 , pp. 35-45
    • Geiger, T.1    Muller, M.2    Dean, N.M.3    Fabbro, D.4
  • 17
    • 0032730633 scopus 로고    scopus 로고
    • Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer
    • Yuen A.R., Halsey J., Fisher G.A., et al. Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer. Clin. Cancer Res. 5:1999;3357-3363.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3357-3363
    • Yuen, A.R.1    Halsey, J.2    Fisher, G.A.3
  • 18
    • 0000014313 scopus 로고    scopus 로고
    • A phase I/II trial of ISIS 3521, an antisense inhibotro of protein kinase C alpha, combined with carboplatin and paclitaxel in patients with non-small cell lung cancer
    • Yuen A., Advani R., Fisher G., et al. A phase I/II trial of ISIS 3521, an antisense inhibotro of protein kinase C alpha, combined with carboplatin and paclitaxel in patients with non-small cell lung cancer. Am. Soc. Clin. Oncol. 19:2000;167.
    • (2000) Am. Soc. Clin. Oncol. , vol.19 , pp. 167
    • Yuen, A.1    Advani, R.2    Fisher, G.3
  • 19
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 20
    • 0021679848 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
    • Tsujimoto Y., Finger L.R., Yunis J., Nowell P.C., Croce C.M. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science. 226:1984;1097-1099.
    • (1984) Science , vol.226 , pp. 1097-1099
    • Tsujimoto, Y.1    Finger, L.R.2    Yunis, J.3    Nowell, P.C.4    Croce, C.M.5
  • 21
    • 0030807543 scopus 로고    scopus 로고
    • A novel antisense oligonucleotide targeting the coding region of the bcl-2 mRNA is a potent inducer of apoptosis in small cell lung cancer cells
    • Ziegler A., Luedke G.H., Fabbro D., Altmann K.H., Stahel R.A., Zangemeister-Wittke U. A novel antisense oligonucleotide targeting the coding region of the bcl-2 mRNA is a potent inducer of apoptosis in small cell lung cancer cells. J. Natl. Cancer Inst. 89:1997;1027-1036.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1027-1036
    • Ziegler, A.1    Luedke, G.H.2    Fabbro, D.3    Altmann, K.H.4    Stahel, R.A.5    Zangemeister-Wittke, U.6
  • 22
    • 0031664988 scopus 로고    scopus 로고
    • Synergistic cytotoxicity of bcl-2 antisense and etoposide, doxorubicin and cisplatin in small cell lung cancer cells
    • Zangemeister-Wittke U., Schenker T., Luedke G.H., Stahel R.A. Synergistic cytotoxicity of bcl-2 antisense and etoposide, doxorubicin and cisplatin in small cell lung cancer cells. Br. J. Cancer. 78:1998;1035-1042.
    • (1998) Br. J. Cancer , vol.78 , pp. 1035-1042
    • Zangemeister-Wittke, U.1    Schenker, T.2    Luedke, G.H.3    Stahel, R.A.4
  • 23
    • 0034684471 scopus 로고    scopus 로고
    • Chemosensitisation of malignant melanoma by bcl-2 antisense therapy
    • Jansen B., Wacheck V., Heere-Ress E., et al. Chemosensitisation of malignant melanoma by bcl-2 antisense therapy. Lancet. 356:2000;1728-1733.
    • (2000) Lancet , vol.356 , pp. 1728-1733
    • Jansen, B.1    Wacheck, V.2    Heere-Ress, E.3
  • 24
    • 0034071150 scopus 로고    scopus 로고
    • Induction of apoptosis in lung cancer cells following bcl-xL antisense treatment
    • Leech S.H., Olie R.A., Gautschi O., et al. Induction of apoptosis in lung cancer cells following bcl-xL antisense treatment. Int. J. Cancer. 86:2000;570-576.
    • (2000) Int. J. Cancer , vol.86 , pp. 570-576
    • Leech, S.H.1    Olie, R.A.2    Gautschi, O.3
  • 25
    • 0036830417 scopus 로고    scopus 로고
    • Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide
    • Simoes-Wust A., Schürpf T., Hall J., Stahel R.A., Zangemeister-Wittke U. bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. Breast Cancer Res. Treat. 76:2002;157-166.
    • (2002) Breast Cancer Res. Treat. , vol.76 , pp. 157-166
    • Simoes-Wust, A.1    Schürpf, T.2    Hall, J.3    Stahel, R.A.4    Zangemeister-Wittke, U.5
  • 26
    • 0003826861 scopus 로고    scopus 로고
    • Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
    • Taylor J.K., Zhang Q.Q., Wyatt J.R., Dean N.M. Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat. Biotechnol. 17:1999;1097-1100.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1097-1100
    • Taylor, J.K.1    Zhang, Q.Q.2    Wyatt, J.R.3    Dean, N.M.4
  • 27
    • 0034659691 scopus 로고    scopus 로고
    • Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense BCL-XL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model
    • Miyake H., Monia B.P., Gleave M.E. Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense BCL-XL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model. Int. J. Cancer. 86:2000;855-862.
    • (2000) Int. J. Cancer , vol.86 , pp. 855-862
    • Miyake, H.1    Monia, B.P.2    Gleave, M.E.3
  • 28
    • 0035925537 scopus 로고    scopus 로고
    • Activity of a novel bcl-2/bcl-xL bispecific antisense oligonucleotide against tumors of diverse histological origins
    • Gautschi O., Tschopp S., Olie R.A., et al. Activity of a novel bcl-2/bcl-xL bispecific antisense oligonucleotide against tumors of diverse histological origins. J. Natl. Cancer Inst. 93:2001;463-471.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 463-471
    • Gautschi, O.1    Tschopp, S.2    Olie, R.A.3
  • 29
    • 0034096268 scopus 로고    scopus 로고
    • A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells
    • Zangemeister-Wittke U., Leech S.H., Olie R.A., et al. A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells. Clin. Cancer Res. 6:2000;2547-2555.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2547-2555
    • Zangemeister-Wittke, U.1    Leech, S.H.2    Olie, R.A.3
  • 30
    • 0034283981 scopus 로고    scopus 로고
    • Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells
    • Moulding D.A., Giles R.V., Spiller D.G., White M.R., Tidd D.M., Edwards S.W. Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells. Blood. 6:2000;1756-1763.
    • (2000) Blood , vol.6 , pp. 1756-1763
    • Moulding, D.A.1    Giles, R.V.2    Spiller, D.G.3    White, M.R.4    Tidd, D.M.5    Edwards, S.W.6
  • 31
    • 0038806293 scopus 로고    scopus 로고
    • Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
    • in press
    • Thallinger C, Wolschek MF, Wacheck V, et al. Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model, J Invest Dermatol, in press.
    • J Invest Dermatol
    • Thallinger, C.1    Wolschek, M.F.2    Wacheck, V.3
  • 33
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • Monia B.P., Johnston J.F., Geiger T., Muller M., Fabbro D. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med. 2:1996;668-675.
    • (1996) Nat. Med. , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.F.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 34
    • 0032984099 scopus 로고    scopus 로고
    • Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A)
    • Stevenson J.P., Yao K.S., Gallagher M., Friedland D., Mitchell E.P., Cassella A., et al. Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A). J. Clin. Oncol. 17:1999;2227-2236.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2227-2236
    • Stevenson, J.P.1    Yao, K.S.2    Gallagher, M.3    Friedland, D.4    Mitchell, E.P.5    Cassella, A.6
  • 35
    • 0034026007 scopus 로고    scopus 로고
    • A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer
    • Cunningham C.C., Holmlund J.T., Schiller J.H., Geary R.S., Kwoh T.J., Dorr A., et al. A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. Clin. Cancer Res. 6:2000;1626-1631.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1626-1631
    • Cunningham, C.C.1    Holmlund, J.T.2    Schiller, J.H.3    Geary, R.S.4    Kwoh, T.J.5    Dorr, A.6
  • 36
    • 0001090536 scopus 로고    scopus 로고
    • Phase II study of c-raf kinase antisense oligonucleotide ISIS 5132 in patients with recurrent ovarian cancer
    • Oza A.M., Eisenhauer E., Swenerton K., et al. Phase II study of c-raf kinase antisense oligonucleotide ISIS 5132 in patients with recurrent ovarian cancer. Clin. Cancer Res. 6:(Suppl.):2000;4572.
    • (2000) Clin. Cancer Res. , vol.6 , Issue.SUPPL. , pp. 4572
    • Oza, A.M.1    Eisenhauer, E.2    Swenerton, K.3
  • 37
    • 0030838791 scopus 로고    scopus 로고
    • In vitro and in vivo activity of antisense inhibitors of ras: Potential for clinical development
    • Cowsert L.M. In vitro and in vivo activity of antisense inhibitors of ras: potential for clinical development. Anticancer Drug Des. 12:1997;359-371.
    • (1997) Anticancer Drug Des. , vol.12 , pp. 359-371
    • Cowsert, L.M.1
  • 38
    • 0026774939 scopus 로고
    • Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
    • Monia B.P., Johnston J.F., Ecker D.J., et al. Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J. Biol. Chem. 267:1992;19954-19962.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19954-19962
    • Monia, B.P.1    Johnston, J.F.2    Ecker, D.J.3
  • 39
    • 0038075807 scopus 로고    scopus 로고
    • Phase I trial of ISIS 2503, an antisense inhibitor of Ha-ras, administered by a 24-h weekly infusion to patients with advanced cancer
    • Atlanta, GA
    • Gordon MS, Sandler AB, Holmlund TJ et al. Phase I trial of ISIS 2503, an antisense inhibitor of Ha-ras, administered by a 24-h weekly infusion to patients with advanced cancer. Presented at the 35th annual meeting of the American Society of Clinical Oncology, Atlanta, GA, 1999.
    • (1999) 35th Annual Meeting of the American Society of Clinical Oncology
    • Gordon, M.S.1    Sandler, A.B.2    Holmlund, T.J.3
  • 40
    • 0028218440 scopus 로고
    • Protein kinase A (PK-A) regulatory subunit expression in colorectal cancer and related mucosa
    • Bradbury A.W., Carter D.C., Miller W.R., Cho-Chung Y.S., Clair T. Protein kinase A (PK-A) regulatory subunit expression in colorectal cancer and related mucosa. Br. J. Cancer. 69:1994;738-742.
    • (1994) Br. J. Cancer , vol.69 , pp. 738-742
    • Bradbury, A.W.1    Carter, D.C.2    Miller, W.R.3    Cho-Chung, Y.S.4    Clair, T.5
  • 41
    • 0034130453 scopus 로고    scopus 로고
    • Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production
    • Tortora G., Bianco R., Damiano V., et al. Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production. Clin. Cancer Res. 6:2000;2506-2512.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2506-2512
    • Tortora, G.1    Bianco, R.2    Damiano, V.3
  • 42
    • 0038075808 scopus 로고    scopus 로고
    • Phase I trial of a second-generation oligonucleotide (GEM231) targeted at type I protein kinase A in patients with refractory solid tumors
    • Atlanta, GA
    • Chen. H, Ness E, Marshall J et al. Phase I trial of a second-generation oligonucleotide (GEM231) targeted at type I protein kinase A in patients with refractory solid tumors. Presented at the 35th annual meeting of the American Society of Clinical Oncology, Atlanta, GA, 1999.
    • (1999) 35th Annual Meeting of the American Society of Clinical Oncology
    • Chen, H.1    Ness, E.2    Marshall, J.3
  • 43
    • 0037083472 scopus 로고    scopus 로고
    • Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
    • July L.V., Akbari M., Zellweger T., Jones E.C., Goldenberg S.L., Gleave M.E. Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate. 50:2002;179-188.
    • (2002) Prostate , vol.50 , pp. 179-188
    • July, L.V.1    Akbari, M.2    Zellweger, T.3    Jones, E.C.4    Goldenberg, S.L.5    Gleave, M.E.6
  • 44
    • 0034870685 scopus 로고    scopus 로고
    • Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin
    • Zellweger T., Miyake H., July L.V., Akbari M., Kiyama S., Gleave M.E. Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin. Neoplasia. 3:2001;360-367.
    • (2001) Neoplasia , vol.3 , pp. 360-367
    • Zellweger, T.1    Miyake, H.2    July, L.V.3    Akbari, M.4    Kiyama, S.5    Gleave, M.E.6
  • 45
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins - Suppressors of apoptosis
    • Deveraux Q.L., Reed J.C. IAP family proteins - suppressors of apoptosis. Genes Dev. 13:1999;239-252.
    • (1999) Genes Dev. , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 46
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri D.C. Validating survivin as a cancer therapeutic target. Nat. Rev. Cancer. 3:2003;46-54.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 47
    • 0342657718 scopus 로고    scopus 로고
    • A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
    • Olie R.A., Simoes-Wust A.P., Baumann B., et al. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res. 60:2000;2805-2809.
    • (2000) Cancer Res. , vol.60 , pp. 2805-2809
    • Olie, R.A.1    Simoes-Wust, A.P.2    Baumann, B.3
  • 48
    • 0032768772 scopus 로고    scopus 로고
    • Heat shock proteins as cellular lifeguards
    • Jaattela M. Heat shock proteins as cellular lifeguards. Ann. Med. 31:1999;261-271.
    • (1999) Ann. Med. , vol.31 , pp. 261-271
    • Jaattela, M.1


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